Abstract:
:Entrapped cells of P. diminuta were used for the production of 7-aminocephalosporanic acid (7-ACA), a key intermediate required for the production of most of the clinically used cephalosporin derivatives, i.e., semisynthetic cephalosporins. The repeated batch production of 7-ACA with entrapped cells of P. diminuta in different carriers were carried out for six cycles at optimal conditions. It was found that 33% , 38%, and 47% of activity was lost with chitosan, gelatin, and agar, respectively as immobilizing supports after the sixth cycle of operation.
journal_name
Appl Biochem Biotechnoljournal_title
Applied biochemistry and biotechnologyauthors
Nigam VK,Kundu S,Ghosh Pdoi
10.1007/s12010-007-9214-4subject
Has Abstractpub_date
2007-04-01 00:00:00pages
119-26issue
1eissn
0273-2289issn
1559-0291pii
ABAB:141:1:119journal_volume
141pub_type
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