Abstract:
:The purpose was to evaluate low-dose CT colonography without cathartic cleansing in terms of image quality, polyp visualization and patient acceptance. Sixty-one patients scheduled for colonoscopy started a low-fiber diet, lactulose and amidotrizoic-acid for fecal tagging 2 days prior to the CT scan (standard dose, 5.8-8.2 mSv). The original raw data of 51 patients were modified and reconstructed at simulated 2.3 and 0.7 mSv levels. Two observers evaluated the standard dose scan regarding image quality and polyps. A third evaluated the presence of polyps at all three mSv levels in a blinded prospective way. All observers were blinded to the reference standard: colonoscopy. At three times patients were given questionnaires relating to their experiences and preference. Image quality was sufficient in all patients, but significantly lower in the cecum, sigmoid and rectum. The two observers correctly identified respectively 10/15 (67%) and 9/15 (60%) polyps > or =10 mm, with 5 and 8 false-positive lesions (standard dose scan). Dose reduction down to 0.7 mSv was not associated with significant changes in diagnostic value (polyps > or =10 mm). Eighty percent of patients preferred CT colonography and 13% preferred colonoscopy (P<0.001). CT colonography without cleansing is preferred to colonoscopy and shows sufficient image quality and moderate sensitivity, without impaired diagnostic value at dose-levels as low as 0.7 mSv.
journal_name
Eur Radioljournal_title
European radiologyauthors
Florie J,van Gelder RE,Schutter MP,van Randen A,Venema HW,de Jager S,van der Hulst VP,Prent A,Bipat S,Bossuyt PM,Baak LC,Stoker Jdoi
10.1007/s00330-007-0668-0subject
Has Abstractpub_date
2007-12-01 00:00:00pages
3112-22issue
12eissn
0938-7994issn
1432-1084journal_volume
17pub_type
杂志文章abstract::Ultrasound (US) of the paediatric chest has become an established imaging tool that may supplement plain film findings helping to reduce or tailor other ionizing (sectional) imaging in a variety of paediatric conditions such as sequestration or pneumonia. US has been shown to offer valuable imaging alternatives, both ...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-007-0754-3
更新日期:2008-02-01 00:00:00
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journal_title:European radiology
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journal_title:European radiology
pub_type: 杂志文章
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更新日期:2001-01-01 00:00:00