Abstract:
:There are no non-invasive methods to assess the real tumor size in rectal cancer prior to surgery, especially following radio/chemotherapy. Magnetic resonance imaging is gaining increasing acceptance as the primary modality at many centers for evaluation of pelvic malignancies including rectal cancers. The aim of this study was to evaluate if the tumor size as assessed by stereological or metric means on MRI correlates to the corresponding pathologic findings. To our knowledge, no such previous work has been reported in the literature. From the Cancer Register Center, 18 patients in the age range of 39-90 years with rectal cancer who had complete preoperative MR with subsequent giant section pathological examinations of the resected bowel were included. The tumor size was measured on MR and histopathologic specimen using both a stereologic and a metric mode. The measured parameters included the maximum transverse area occupied by the tumor, thickness, width, and the length of tumor and the volume of the tumor measured in two different fashions by the product of area and length (al) or the product of thickness, width, and length (twl). The depth of tumor infiltration (T) and presence of local lymph node metastases (N) were also separately evaluated on the histopathologic specimen. There were 1, 4, 12, and 1 patients with tumor stages T1, T2, T3, and T4, respectively. The mean thickness, width, length, area, and volumes, al and twl, were 1.62, 2.8, and 4.78 cm, and 4.72 cm2, 26.29 cm3, and 20.07 cm3, respectively. Regression curves were drawn for above-mentioned parameters. They showed some correlation with square correlation coefficient measuring between 0.38 and 0.82. The best correlation was seen for area (0.75) and volume measured by the product of area and length of the tumor (0.82). With the formula proposed from this material, we assume that rectal tumors can be measured on MR images using a metric model, especially area and the volume (the product of area and length), and then extrapolated to what we would expect from pathology, hence providing us with a tool where we could measure tumor response after neoadjuvant therapy.
journal_name
Eur Radioljournal_title
European radiologyauthors
Torkzad M,Lindholm J,Martling A,Blomqvist Ldoi
10.1007/s00330-003-1898-4subject
Has Abstractpub_date
2003-10-01 00:00:00pages
2271-7issue
10eissn
0938-7994issn
1432-1084journal_volume
13pub_type
杂志文章abstract::The objective of this paper is to quantify the fatty degeneration (infiltration) of rotator cuff muscles with a new spectroscopic FLASH (SPLASH) sequence. Before planned surgery (reconstruction or muscle transfer), 20 patients (13 men, 7 women; 35-75 years) with different stages of rotator cuff disease underwent an MR...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2410-5
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVE:To compare the performance of synthetic mammography (SM) and digital mammography (DM) with digital breast tomosynthesis (DBT) or alone for the evaluation of microcalcifications. METHODS:This retrospective study includes 198 mammography cases, all with DM, SM, and DBT images, from January to October 2013. Thr...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5585-x
更新日期:2019-01-01 00:00:00
abstract::The aim of this study was to determine whether the intrarenal resistive index (RI) can be used for the diagnosis of acute obstruction in patients with renal colic and to determine whether the index is time-related. Seventy patients referred to the Emergency Department with acute renal colic and without known associate...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050568
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVES:Investigate the effect of a novel Bayesian penalised likelihood (BPL) reconstruction algorithm on analysis of pulmonary nodules examined with 18F-FDG PET/CT, and to determine its effect on small, sub-10-mm nodules. METHODS:18F-FDG PET/CTs performed for nodule evaluation in 104 patients (121 nodules) were re...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-3832-y
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVES:To assess if the administration of gadoxetate disodium (Gd-EOB-DTPA) significantly affects hepatic magnetic resonance elastography (MRE) measurements in the delayed hepatobiliary phase (DHBP). METHODS:A total of 47 patients (15 females, 32 males; age range 23-78 years, mean 54.28 years) were assigned to sta...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5616-7
更新日期:2019-02-01 00:00:00
abstract::Although spatial resolution of current MR angiography is excellent, temporal resolution has remained unsatisfactory. We evaluated clinical applicability of 2D thick-slice, contrast-enhanced subtraction MR angiography (2D-MR digital subtraction angiography) with sub-second temporal resolution in cerebrovascular occlusi...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000584
更新日期:2000-01-01 00:00:00
abstract::Lymphoma is a spectrum of malignant neoplasms of the lymphoid system. The appearances radiologically are diverse with almost all organs susceptible to involvement. The condition is challenging as it can mimic the appearance of almost all other neoplasms. This review highlights in a general way the diversity of the rad...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-002-1632-7
更新日期:2003-05-01 00:00:00
abstract::The aim of this study was to assess radiomorphologic and clinical features of tracheal rupture due to blunt chest trauma. From 1992 until 1998 the radiomorphologic and clinical key findings of all consecutive tracheal ruptures were retrospectively analyzed. The study included ten patients (7 men and 3 women; mean age ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050080
更新日期:2000-01-01 00:00:00
abstract::Imaging methods assist in the pre-treatment planning of laryngeal and hypopharyngeal neoplasms, by better defining the local extension of infiltrating tumours and by detecting subclinical neck adenopathies. Imaging has also an important role in excluding or detecting distant metastasis. Furthermore, there is evidence ...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-006-0301-7
更新日期:2006-11-01 00:00:00
abstract::Developmental nasal midline masses in children are rare lesions. Neuroimaging is essential to characterise these lesions, to determine the exact location of the lesion and most importantly to exclude a possible intracranial extension or connection. Our objective was to evaluate CT and MRI in the diagnosis of developme...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-003-2008-3
更新日期:2004-02-01 00:00:00
abstract::Sacral insufficiency fractures develop over a period of time and show time-dependent changes. We report on 15 CT examinations of 5 patients with early-stage insufficiency fractures of the sacrum. In 4 patients only irregular sclerosis without distinct fracture lines was present in 7 of 8 fractures. Of these 4 patients...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/BF00187667
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:To determine the diagnostic accuracy of diffusion-weighted (DW) magnetic resonance (MR) imaging in the preoperative assessment of myometrial invasion by endometrial cancer. MATERIALS AND METHODS:In this prospective study, 47 patients with histologically confirmed endometrial cancer underwent preoperative MR ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-009-1597-x
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVES:To compare [(18)F]FDG PET/MRI with PET/CT for the assessment of bone lesions in oncologic patients. METHODS:This prospective study included 67 patients with solid tumours scheduled for PET/CT with [(18)F]FDG who also underwent a whole-body PET/MRI scan. The datasets (PET/CT, PET/MRI) were rated by two reade...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3229-3
更新日期:2014-08-01 00:00:00
abstract::Adenocarcinoma is the most common malignant pancreatic tumor, affecting the head of the pancreas in 60-70% of cases. By the time of diagnosis, at least 80% of tumors are unresectable. Helical computed tomography (CT) is very effective in detecting and staging adenocarcinoma, with a sensitivity of up to 90% for detecti...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-006-0435-7
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:To investigate the impact of automated attenuation-based tube potential selection on image quality and exposure parameters in polytrauma patients undergoing contrast-enhanced thoraco-abdominal CT. METHODS:One hundred patients were examined on a 16-slice device at 120 kV with 190 ref.mAs and automated mA modu...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3197-7
更新日期:2014-07-01 00:00:00
abstract::The value of 31P-magnetic resonance spectroscopy (MRS) as a possible tool to distinguish viable from non-viable tissue after myocardial infarction was analysed in humans. Fifteen patients 3 weeks after anterior myocardial infarction were studied with breath-hold cine MRI and 3D-CSI MRS (1.5 T system). 31P-spectra were...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000316
更新日期:2000-01-01 00:00:00
abstract::The aim of this study was to revisit anal anatomy, to explain surgical terminology in perianal complications of Crohn disease, and to show the MR imaging findings of perianal fistulas and abscesses. To this end more than 200 patients were studied using surface coils (Helmholtz; phased array) at 1.0 and 1.5 T. Transver...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050248
更新日期:1997-01-01 00:00:00
abstract::The aim of our study was to assess whether contrast-enhanced CT colonography is a feasible alternative to both conventional colonoscopy and liver ultrasonography in the follow-up program of colorectal cancer patients. Thirty-five patients, surgically treated for colorectal cancer, underwent a follow-up program that in...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1696-4
更新日期:2003-04-01 00:00:00
abstract::The aim of this study was to assess the efficacy of a superparamagnetic iron oxide, ferumoxides, in the detection and characterization of focal nodular hyperplasia (FNH) on MR conventional spin-echo (SE), fast spin-echo (FSE) and gradient-echo (GRE) images. Fourteen adults with 27 FNHs were evaluated at 1.5 T before a...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050879
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVES:To develop a model for differentiating the predominant subtype-based prognostic groups of lung adenocarcinoma using CT radiomic features, and to validate its performance in comparison with radiologists' assessments. METHODS:A total of 993 patients presenting with invasive lung adenocarcinoma between March 2...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-06805-w
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:To develop a fully automated AI system to quantitatively assess the disease severity and disease progression of COVID-19 using thick-section chest CT images. METHODS:In this retrospective study, an AI system was developed to automatically segment and quantify the COVID-19-infected lung regions on thick-secti...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07042-x
更新日期:2020-12-01 00:00:00
abstract::Cardiac angiosarcoma is a rare tumour entity with a poor prognosis. Early detection is difficult but important for the further course of the disease. We report on a young patient with a tumour of unknown origin and dignity of the right atrium. Magnetic resonance imaging, CT and echocardiography were sufficient in loca...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1478-z
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVES:To evaluate the impact of model-based iterative reconstruction (MBIR) on image quality and low-contrast lesion detection compared with filtered back projection (FBP) in abdominal computed tomography (CT) of simulated medium and large patients at different tube voltages. METHODS:A phantom with 45 hypoattenua...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-4825-9
更新日期:2017-12-01 00:00:00
abstract::The peritoneum is a mesothelial lining of the abdominal cavity (parietal) and intraperitoneal viscera (visceral). The cavity contains a small amount of fluid, which circulates from cephalad to caudal to cephalad, influenced by negative pressure under the diaphragm during exhalation, gravity, and bowel peristalsis. Per...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300100998
更新日期:2001-01-01 00:00:00
abstract::The arrival of new surgical transplantation techniques, such as split living donor or auxiliary liver transplantation, have increased the incidence of vascular and biliary complications. The causes, symptoms, and diagnostic modalities of arterial, portal caval, and biliary complications are detailed. Interventional te...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-003-2196-x
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:As stents for treating intracranial atherosclerotic stenosis may develop in-stent re-stenosis (ISR) in up to 30%, follow-up imaging is mandatory. Residual stenosis (RS) is not rare. We evaluated an optimised Flat Detector CT protocol with intravenous contrast material application (i.v. FD-CTA) for non-invasiv...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-1931-3
更新日期:2011-02-01 00:00:00
abstract::The appearances of knee injuries on MR imaging are less well documented in children than adults. Some patterns of injury are shared by both groups of patients, e. g. meniscal damage. The frequency of specific injuries may differ, e. g. anterior cruciate ligament (ACL) tear. Congenital abnormality, coexistent pathology...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300050284
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVES:To study linear and volumetric adrenal measurements, their reproducibility, and correlations between total adrenal volume (TAV) and adrenal micronodularity, age, gender, body mass index (BMI), visceral (VAAT) and subcutaneous adipose tissue volume (SAAT), presence of diabetes, chronic alcoholic abuse and chr...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-4063-y
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVES:To prospectively assess reproducibility, safety, and efficacy of microwave ablation (MWA) in the treatment of unresectable primary and secondary pulmonary tumors. METHODS:Patients with unresectable primary and metastatic lung tumors up to 4 cm were enrolled in a multicenter prospective clinical trial and un...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07299-2
更新日期:2020-09-30 00:00:00
abstract::Noonan's syndrome is a rare congenital disorder that may be associated with abnormalities in the lymphatic drainage. In this case of a 21-year-old man CT after bipedal lymphangiography confirmed the diagnosis of intestinal lymphangiectasy causing protein-losing enteropathy in Noonan's syndrome by showing contrast-enha...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000384
更新日期:2000-01-01 00:00:00