Abstract:
:The potential for low dose computed tomography (LDCT) to act as an effective tool in screening for lung cancer is currently the subject of several randomised control trials. It has recently been given prominence by interim results released by the North American National Lung Screening Trial (NLST). Several other trials assessing LDCT as a screening tool are currently underway in Europe, and are due to report their final results in the next few years. These include the NELSON, DLSCT, DANTE, ITALUNG, MILD and LUSI trials. Although slow to instigate a trial of its own, the UK Lung Screen (UKLS) trial will shortly commence. The knowledge gained from the newer trials has mostly reinforced and refined previous concepts that have formed the basis of existing nodule management guidelines. This article takes the opportunity to summarise the main aspects and initial results of the trials presently underway, assess the status of current collaborative efforts and the scope for future collaboration, and analyse observations from these studies that may usefully inform the management of the indeterminate pulmonary nodule. Key Points • Low dose CT screening for lung cancer is promising. • The effect of LDCT screening on mortality is still uncertain. • Several European randomised controlled trials for LDCT are underway. • The trials vary in methodology but most compare LDCT to no screening. • Preliminary results have reinforced existing nodule management concepts.
journal_name
Eur Radioljournal_title
European radiologyauthors
Nair A,Hansell DMdoi
10.1007/s00330-011-2219-ysubject
Has Abstractpub_date
2011-12-01 00:00:00pages
2445-54issue
12eissn
0938-7994issn
1432-1084journal_volume
21pub_type
杂志文章,评审abstract::We performed a bibliometric search to evaluate number and scientific "weight" of papers written by European radiologists, as compared with colleagues from other countries, to measure the contribution of European researchers to radiology journals, and to correlate bibliometric parameters with some socio-economic factor...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1640-7
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVES:To determine whether changes in ADC of bone metastases secondary to prostate carcinoma are significantly different in responders compared with progressors on chemotherapy. METHODS:Twenty-six patients with known bone metastases secondary to prostate carcinoma underwent diffusion-weighted MRI of the lumbar sp...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-011-2173-8
更新日期:2011-10-01 00:00:00
abstract::Fat necrosis of the breast is a well-known complication following trauma, surgery, or radiotherapy. The present paper describes a rare case of fat necrosis after heparin-induced thrombocytopenia. The mammographic, sonographic, and MR evaluation and pathologic correlation after a 1-year follow-up period are reported. ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050090
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:We investigated the potential reduction of patient exposure during invasive coronary angiography (ICA) if the procedure had only been directed to the vessel with at least one ≥ 50% stenosis as described in the CT report. METHODS:Dose reports of 61 patients referred to ICA because of at least one ≥ 50% steno...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5317-2
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVES:To determine whether positioning of the arm in adduction and internal rotation would improve the confidence in the diagnosis of Bankart lesions in first time shoulder dislocators. METHODS:Eleven patients were imaged on an open bore MRI within 1-6 days of traumatic shoulder dislocation with the arm adducted ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2655-3
更新日期:2013-03-01 00:00:00
abstract:UNLABELLED:Magnetic resonance (MR) imaging has been definitively established as the reference standard in the evaluation of joints in the body. Similarly, magnetic resonance arthrography has emerged as a technique that has been proven to increase significantly the diagnostic performance if compared with conventional MR...
journal_title:European radiology
pub_type: 社论
doi:10.1007/s00330-015-3945-3
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:To investigate the value of histogram analysis of diffusion kurtosis imaging (DKI) maps in the evaluation of glioma grading. METHODS:A total of 39 glioma patients who underwent preoperative magnetic resonance imaging (MRI) were classified into low-grade (13 cases) and high-grade (26 cases) glioma groups. Par...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-5108-1
更新日期:2018-04-01 00:00:00
abstract::To determine whether neutral contrast agents with water-equivalent intraluminal attenuation can improve delineation of the bowel wall and increase overall image quality for a non-selected patient population, a neutral oral contrast agent (3% mannitol) was administered to 100 patients referred for abdominal multidetect...
journal_title:European radiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00330-008-0958-1
更新日期:2008-09-01 00:00:00
abstract::An unusual case of myositis ossificans traumatica lesion located in the paraspinal region is reported. Despite the contiguity of the lesion with the cervical vertebrae and ominous appearance of the biopsy material, the history of antecedent trauma and computed tomography findings allowed preoperative accurate diagnosi...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050728
更新日期:1999-01-01 00:00:00
abstract::The purpose of our animal study was to evaluate a new computed tomography (CT) subtraction technique for visualization of perfusion defects within the lung parenchyma in subsegmental pulmonary embolism (PE). Seven healthy pigs were entered into a prospective trial. Acute PE was artificially induced by fresh clot mater...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-005-2718-9
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVE:To assess the radiation dose received by the radiologist when performing wire localisation for axillary radio-isotope sentinel node imaging-guided biopsy in patients with impalpable breast cancers treated with breast-preserving excision. When wire placement follows radio-isotope sentinel node imaging (RSNI) t...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-009-1594-0
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVES:To determine if radiomic features, alone or combined with clinical data, are associated with residual tumour (RT) at surgery, and predict the risk of disease progression within 12 months (PD12) in ovarian cancer (OC) patients. METHODS:This retrospective study enrolled 101 patients according to the following...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5389-z
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVES:To characterize interhemispheric functional and anatomical connectivity and their relationships with impulsive behaviour in codeine-containing cough syrup (CCS)-dependent male adolescents and young adults. METHODS:We compared volumes of corpus callosum (CC) and its five subregion and voxel-mirrored homotopi...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4465-5
更新日期:2017-03-01 00:00:00
abstract::This study aimed to assess the feasibility of quantification of bronchial dimensions at MDCT using dedicated software (BronCare). We evaluated the reliability of the software to segment the airways and defined criteria ensuring accurate measurements. BronCare was applied on two successive examinations in 10 mild asthm...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-006-0496-7
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVES:The aim of our study was to evaluate the tumour volume doubling time (TVDT) of molecular breast cancer subtypes by serial ultrasound (US). METHODS:Sixty-six patients (mean age, 50 years; range, 29-78 years) with invasive breast cancer underwent initial and follow-up breast US examinations (at least three mo...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3256-0
更新日期:2014-09-01 00:00:00
abstract::The aim of the study was to document MRI findings in masticator structures in patients with trismus developing after radiotherapy for nasopharyngeal carcinoma (NPC). MRI neck examinations were reviewed in 35 patients with marked trismus, defined as an interincisal gap of 25 mm or less, post-radiotherapy for NPC. Patie...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-009-1445-z
更新日期:2009-11-01 00:00:00
abstract::At present, medical applications applying World Wide Web (WWW) technology are mainly used to view static images and to retrieve some information. The Java platform is a relative new way of computing, especially designed for network computing and distributed applications which enables interactive connection between use...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000432
更新日期:2000-01-01 00:00:00
abstract::The purpose of this study was to evaluate the scope of sub-millimeter collimation reconstruction parameters using 16-row computer tomography and ECG triggering on image quality in virtual bronchoscopy. Thirty-two patients (5 women, 27 men, mean age 66.6+/-1.4) who had been admitted for coronary artery bypass graft sur...
journal_title:European radiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00330-004-2325-1
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVES:To investigate the hepatobiliary enhancement patterns of gadoxetic acid (Gd-EOB-DTPA) MRI and the temporal evolution of focal nodular hyperplasia (FNH)-like lesions in pediatric cancer survivors. METHODS:We retrospectively included pediatric cancer survivors who had new liver lesions detected during surveil...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07157-1
更新日期:2021-01-01 00:00:00
abstract::This study was designed to compare the incidence of mechanical, thrombotic and infective complications in transjugular (IJV) and axillosubclavian (SCV) central venous catheters (CVC) in patients with hematological malignancy. In a prospective observational trial, 131 consecutive patients were classified into two group...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-005-2641-0
更新日期:2005-06-01 00:00:00
abstract::The aim of this study was to test the influence of observer experience on the accuracy for interpreting helical CT for acute pulmonary embolism (PE) and to identify sources of observer errors. Three observers of different expertise blindly assessed 147 helical CT scans for suspected PE (true status regarding absence o...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050526
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVES:To describe the spectrum of brainstem malformations associated to mutations in the tubulin genes taking advantage of magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI). METHODS:Fifteen patients (six males; median age, 1.25 years; range, 1 month to 31 years) with mutations in the tubulin gen...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5610-0
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:The apparent diffusion coefficient (ADC) is increasingly used as a quantitative biomarker in oncological imaging. ADC calculation is based on raw diffusion-weighted imaging (DWI) data, and multiple post-processing methods (PPMs) have been proposed for this purpose. We investigated whether PPM has an impact on...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4403-6
更新日期:2017-03-01 00:00:00
abstract::The goal of this study was 3-month clinical outcome in nonanticoagulated patients with clinically suspected acute pulmonary embolism (PE) following a negative spiral CT. During a 6-month period 305 patients underwent spiral CT, of whom only 8 also had a lung scintigraphy. In patients with a final CT report read as not...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300000539
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVES:Core biopsy underestimates invasion in more than 20% of patients with preoperatively diagnosed ductal carcinoma in situ (DCIS) without evidence of invasion (pure DCIS). The aim of the current study was to evaluate the efficacy of preoperative magnetic resonance imaging (MRI) to discriminate between patients ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2394-5
更新日期:2012-07-01 00:00:00
abstract::The purpose was to compare the diagnostic accuracy of ferumoxides-enhanced MR imaging and gadolinium-enhanced dynamic MR imaging using three-dimensional (3D) volume interpolated breath-hold examination (VIBE) for the detection of hepatocellular carcinoma (HCC). Forty-nine patients with 61 HCCs, who underwent ferumoxid...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-004-2508-9
更新日期:2005-01-01 00:00:00
abstract::To assess both sensitivity and specificity of digital chest radiography alone and in conjunction with dual-exposure dual-energy chest radiography for the detection and classification of pulmonary nodules. One hundred patients with a total of 149 lung nodules (3-45 mm; median, 11 mm) confirmed by CT were included in th...
journal_title:European radiology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1007/s00330-008-0945-6
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVES:To evaluate diagnostic performance of follow-up MRI for detection of local recurrence of rectal cancer after transanal endoscopic microsurgery (TEM). METHODS:Between January 2006 and February 2014, 81 patients who underwent TEM were included. Two expert readers (R1 and R2), independently evaluated T2-weight...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-4853-5
更新日期:2017-12-01 00:00:00
abstract::The aim of this study was to analyze the precision of tibial cartilage morphometry, by using a fast, coronal water-excitation sequence with high spatial resolution, to compare the reproducibility of 3D thickness vs volume estimates, and to test the technique in patients with severe osteoarthritis. The tibiae of 8 heal...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050047
更新日期:2000-01-01 00:00:00
abstract::Endometriosis is a common gynaecological condition of unknown aetiology that primarily affects women of reproductive age. The accepted first-line imaging modality is pelvic ultrasound. However, magnetic resonance imaging (MRI) is increasingly performed as an additional investigation in complex cases and for surgical p...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4673-z
更新日期:2017-07-01 00:00:00