Tumour volume doubling time of molecular breast cancer subtypes assessed by serial breast ultrasound.

Abstract:

OBJECTIVES:The aim of our study was to evaluate the tumour volume doubling time (TVDT) of molecular breast cancer subtypes by serial ultrasound (US). METHODS:Sixty-six patients (mean age, 50 years; range, 29-78 years) with invasive breast cancer underwent initial and follow-up breast US examinations (at least three months apart) with no intervention. TVDT was determined using the tumours' greatest dimensions in two orthogonal planes. The results were compared with clinical, imaging, and tumour variables and molecular subtypes (oestrogen receptor [ER]-positive, human epidermal growth factor receptor 2 [HER2]-positive, and triple negative) using a multiple linear regression analysis. RESULTS:TVDT exhibited a wide range (46-825 days; median, 141 days) with an overall mean of 193 ± 141 days and mean values of 241 ± 166 days for ER-positive tumours (n = 37), 162 ± 60 days for HER2-positive tumours (n = 12), and 103 ± 43 days for triple-negative tumours (n = 17) (P < 0.0001). In a multivariate regression analysis, compared to other features, only the different molecular breast cancer subtypes showed significant difference in TVDT (P < 0.0001). CONCLUSIONS:TVDT differed significantly among the three molecular breast cancer subtypes, with the triple-negative tumours showing the fastest growth. KEY POINTS:Knowledge of tumour volume doubling time provides clues for improving screening. TVDT assessed by serial US differed significantly between breast cancer subtypes. Triple-negative tumours had 2.4-fold shorter TVDT compared to ER-positive tumours. Tumours classified as BI-RADS 3 had shorter TVDT than BI-RADS 4.

journal_name

Eur Radiol

journal_title

European radiology

authors

Ryu EB,Chang JM,Seo M,Kim SA,Lim JH,Moon WK

doi

10.1007/s00330-014-3256-0

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

2227-35

issue

9

eissn

0938-7994

issn

1432-1084

journal_volume

24

pub_type

杂志文章
  • CT-guided core-needle biopsy in the diagnosis of mediastinal lymphoma.

    abstract::The advent of radiologic guidance techniques for percutaneous biopsy has changed the approach to the routine diagnosis of mediastinal lymphoma. The aim of the present study was to evaluate the diagnostic accuracy of CT-guided percutaneous core-needle biopsy (PCNB) in the clinical management of patients with mediastina...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300050991

    authors: Sklair-Levy M,Polliack A,Shaham D,Applbaum YH,Gillis S,Ben-Yehuda D,Sherman Y,Libson E

    更新日期:2000-01-01 00:00:00

  • Lumbar muscle volume in postmenopausal women with osteoporotic compression fractures: quantitative measurement using MRI.

    abstract:OBJECTIVE:To investigate the relationship between paraspinal and psoas muscle volumes and acute osteoporotic or low-bone-mass compression fractures of the lumbar spine in postmenopausal women. METHODS:Patient data were retrieved retrospectively for postmenopausal women with L-spine magnetic resonance imaging (MRI) and...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-019-06034-w

    authors: Huang CWC,Tseng IJ,Yang SW,Lin YK,Chan WP

    更新日期:2019-09-01 00:00:00

  • Radial scars diagnosed at stereotactic core-needle biopsy: surgical biopsy findings.

    abstract::We retrospectively reviewed surgical biopsy findings of lesions diagnosed as radial scars (RS) at stereotactic core-needle biopsy (SCNB). RS was diagnosed in 52 of 1415 (3.7%) consecutive mammographically detected lesions that underwent 14-gauge automated SCNB. Subsequent surgical biopsy findings were available for 43...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-006-0196-3

    authors: López-Medina A,Cintora E,Múgica B,Operé E,Vela AC,Ibañez T

    更新日期:2006-08-01 00:00:00

  • Automatic exposure control in CT: the effect of patient size, anatomical region and prescribed modulation strength on tube current and image quality.

    abstract:OBJECTIVES:To study the effect of patient size, body region and modulation strength on tube current and image quality on CT examinations that use automatic tube current modulation (ATCM). METHODS:Ten physical anthropomorphic phantoms that simulate an individual as neonate, 1-, 5-, 10-year-old and adult at various body...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-014-3309-4

    authors: Papadakis AE,Perisinakis K,Damilakis J

    更新日期:2014-10-01 00:00:00

  • Nomogram including pretherapeutic parameters for prediction of survival after SIRT of hepatic metastases from colorectal cancer.

    abstract:OBJECTIVES:Pre-therapeutic prediction of outcome is important for clinicians and patients in determining whether selective internal radiation therapy (SIRT) is indicated for hepatic metastases of colorectal cancer (CRC). METHODS:Pre-therapeutic characteristics of 100 patients with colorectal liver metastases (CRLM) tr...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-015-3658-7

    authors: Fendler WP,Ilhan H,Paprottka PM,Jakobs TF,Heinemann V,Bartenstein P,Khalaf F,Ezziddin S,Hacker M,Haug AR

    更新日期:2015-09-01 00:00:00

  • Effect of radiation dose level on the detectability of pulmonary nodules in chest tomosynthesis.

    abstract:OBJECTIVE:To investigate the detectability of pulmonary nodules in chest tomosynthesis at reduced radiation dose levels. METHODS:Eighty-six patients were included in the study and were examined with tomosynthesis and computed tomography (CT). Artificial noise was added to simulate that the tomosynthesis images were ac...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-014-3182-1

    authors: Asplund SA,Johnsson ÅA,Vikgren J,Svalkvist A,Flinck A,Boijsen M,Fisichella VA,Månsson LG,Båth M

    更新日期:2014-07-01 00:00:00

  • Repeat biopsy of patients with acquired resistance to EGFR TKIs: implications of biopsy-related factors on T790M mutation detection.

    abstract:OBJECTIVES:To find predictors of non-diagnostic repeat biopsy specimen acquisition for mutational analysis and detection of epidermal growth factor receptor (EGFR) T790M mutation. METHODS:We retrospectively reviewed 90 non-small cell lung cancer patients harbouring EGFR mutations who underwent repeat cone-beam CT-guid...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-017-5006-6

    authors: Kim H,Chae KJ,Yoon SH,Kim M,Keam B,Kim TM,Kim DW,Goo JM,Park CM

    更新日期:2018-02-01 00:00:00

  • Varicocele: strategies in diagnosis and treatment.

    abstract::Varicocele can be very easily diagnosed by physical examination and subsequently treated when it is painful or associated with testicular hypotrophy. However, palpability of the spermatic vein and reflux in low grade or even questionable varicoceles can be difficult to assess without imaging modalities. This can be a ...

    journal_title:European radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s003300050706

    authors: Cornud F,Belin X,Amar E,Delafontaine D,Hélénon O,Moreau JF

    更新日期:1999-01-01 00:00:00

  • Musculoskeletal imaging with a prototype photon-counting detector.

    abstract:OBJECTIVE:To test a digital imaging X-ray device based on the direct capture of X-ray photons with pixel detectors, which are coupled with photon-counting readout electronics. METHODS:The chip consists of a matrix of 256 × 256 pixels with a pixel pitch of 55 μm. A monolithic image of 11.2 cm × 7 cm was obtained by the...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-011-2246-8

    authors: Gruber M,Homolka P,Chmeissani M,Uffmann M,Pretterklieber M,Kainberger F

    更新日期:2012-01-01 00:00:00

  • Aneurysmal bone cyst of the cervical spine (2008:7b).

    abstract::Aneurysmal bone cysts (ABC) are rare, benign, but locally destructive bone tumors. They occur in the spine in 14% of cases, but only 2% are found in the cervical spine. This case report presents a 16-year-old female with an expansive aneurysmatic bone cyst with extensive bone destruction and instability in the cervica...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-008-0944-7

    authors: Pennekamp W,Peters S,Schinkel C,Kuhnen C,Nicolas V,Muhr G,Frangen TM

    更新日期:2008-10-01 00:00:00

  • En bloc excision of nonpalpable breast lesions using the advanced breast biopsy instrumentation system: an alternative to needle guided surgery?

    abstract::This study was prospectively conducted to evaluate the clinical potential of the advanced breast biopsy instrumentation (ABBI) system as an alternative to needle localization and open surgery in the management of nonpalpable breast lesions (NPBL). One hundred and eighty-six consecutive patients were referred for manag...

    journal_title:European radiology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s003300000736

    authors: Lifrange E,Dondelinger RF,Fridman V,Colin C

    更新日期:2001-01-01 00:00:00

  • The use of imaging in COVID-19-results of a global survey by the International Society of Radiology.

    abstract:OBJECTIVES:This survey conducted by the International Society of Radiology and supported by the European Society of Radiology aimed to collect information regarding radiology departments' current practices in the management of patients with COVID-19. METHODS:Responses from 50 radiology departments involved in the mana...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-020-07252-3

    authors: Blažić I,Brkljačić B,Frija G

    更新日期:2020-09-17 00:00:00

  • Gastrointestinal infection in the immunocompromised (AIDS) patient.

    abstract::In the past two decades acquired immunodeficiency syndrome (AIDS) has become one of the most devastating illnesses in human history. As the epidemic continues to spread increasingly, AIDS patients are no longer confined to a few specialized AIDS hospitals and are now seen in general hospitals and clinics everywhere. R...

    journal_title:European radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00330-003-2065-7

    authors: Reeders JW,Yee J,Gore RM,Miller FH,Megibow AJ

    更新日期:2004-03-01 00:00:00

  • Blood-ocular barrier damage: use of contrast-enhanced MRI.

    abstract::The blood-ocular barrier (BOB) shares similar neuroepithelial origin, microanatomy and functions with the blood-brain barrier. There are many natural (e. g. diabetes, hypertension) or iatrogenic (chemotherapy, retinal photocoagulation) conditions which can cause a BOB breakdown, resulting in visual acuity impairment o...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300050121

    authors: Manfré L,Midiri M,Giuffré G,Mangiameli A,Cardella G,Ponte F,De Maria M,Lagalla R

    更新日期:1997-01-01 00:00:00

  • Feasibility of prospectively ECG-triggered high-pitch coronary CT angiography with 30 mL iodinated contrast agent at 70 kVp: initial experience.

    abstract:OBJECTIVES:To evaluate the feasibility, image quality and radiation dose of prospectively ECG-triggered high-pitch coronary CT angiography (CCTA) with 30 mL contrast agent at 70 kVp. METHODS:Fifty-eight patients with suspected coronary artery disease, a body mass index (BMI) of less than 25 kg/m(2), sinus rhythm and a...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-014-3157-2

    authors: Zhang LJ,Qi L,Wang J,Tang CX,Zhou CS,Ji XM,Spearman JV,De Cecco CN,Meinel FG,Schoepf UJ,Lu GM

    更新日期:2014-07-01 00:00:00

  • Predicting patterns of glioma recurrence using diffusion tensor imaging.

    abstract::Although multimodality therapy for high-grade gliomas is making some improvement in outcome, most patients will still die from their disease within a short time. We need tools that allow treatments to be tailored to an individual. In this study we used diffusion tensor imaging (DTI), a technique sensitive to subtle di...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-006-0561-2

    authors: Price SJ,Jena R,Burnet NG,Carpenter TA,Pickard JD,Gillard JH

    更新日期:2007-07-01 00:00:00

  • Everyman's prostate phantom: kiwi-fruit substitute for human prostates at magnetic resonance imaging, diffusion-weighted imaging and magnetic resonance spectroscopy.

    abstract:OBJECTIVES:To apply an easy-to-assemble phantom substitute for human prostates in T2-weighted magnetic resonance imaging (T2WI), diffusion-weighted imaging (DWI) and 3D magnetic resonance spectroscopy (MRS). METHODS:Kiwi fruit were fixed with gel hot and cold compress packs on two plastic nursery pots, separated by a ...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-016-4706-7

    authors: Mueller-Lisse UG,Murer S,Mueller-Lisse UL,Kuhn M,Scheidler J,Scherr M

    更新日期:2017-08-01 00:00:00

  • Comparison of neutral oral contrast versus positive oral contrast medium in abdominal multidetector CT.

    abstract::To determine whether neutral contrast agents with water-equivalent intraluminal attenuation can improve delineation of the bowel wall and increase overall image quality for a non-selected patient population, a neutral oral contrast agent (3% mannitol) was administered to 100 patients referred for abdominal multidetect...

    journal_title:European radiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00330-008-0958-1

    authors: Berther R,Patak MA,Eckhardt B,Erturk SM,Zollikofer CL

    更新日期:2008-09-01 00:00:00

  • Dynamic MR imaging of osteoid osteomas: correlation of semiquantitative and quantitative perfusion parameters with patient symptoms and treatment outcome.

    abstract:OBJECTIVE:To evaluate the relationship between multiple MR perfusion parameters and symptoms of patients with osteoid osteomas after percutaneous laser therapy. METHODS:MR perfusion studies of 20 patients diagnosed with an osteoid osteoma, treated with CT-guided percutaneous laser therapy, were retrospectively evaluat...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-013-2867-1

    authors: Teixeira PA,Chanson A,Beaumont M,Lecocq S,Louis M,Marie B,Sirveaux F,Blum A

    更新日期:2013-09-01 00:00:00

  • Radiological and clinical predictors of long-term outcome in rotator cuff calcific tendinitis.

    abstract:OBJECTIVES:Knowledge on the epidemiology and long-term course of rotator cuff calcific tendinitis (RCCT) is scarce. We assessed demographics, radiological characteristics, and their association with long-term outcomes in a large patient group. METHODS:Baseline demographics, radiological characteristics and treatment w...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-016-4224-7

    authors: de Witte PB,van Adrichem RA,Selten JW,Nagels J,Reijnierse M,Nelissen RG

    更新日期:2016-10-01 00:00:00

  • MR-guided vacuum-assisted breast biopsy of MRI-only lesions: a single center experience.

    abstract:PURPOSE:The purpose of this study was to compare three different biopsy devices on false-negative and underestimation rates in MR-guided, vacuum-assisted breast biopsy (VABB) of MRI-only lesions. METHODS:This retrospective, single-center study was IRB-approved. Informed consent was waived. 467 consecutive patients und...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-016-4267-9

    authors: Spick C,Schernthaner M,Pinker K,Kapetas P,Bernathova M,Polanec SH,Bickel H,Wengert GJ,Rudas M,Helbich TH,Baltzer PA

    更新日期:2016-11-01 00:00:00

  • Short tau inversion recovery and proton density-weighted fat suppressed sequences for the evaluation of osteoarthritis of the knee with a 1.0 T dedicated extremity MRI: development of a time-efficient sequence protocol.

    abstract::Aim of this study was to develop a time-efficient sequence protocol for a 1.0 T dedicated MR system to be used for whole-organ scoring of osteoarthritis (OA). Thirty-four knees were examined using a protocol that included fat suppressed fast spin echo proton density weighted sequences (PDFS) in three planes plus a cor...

    journal_title:European radiology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00330-004-2608-6

    authors: Roemer FW,Guermazi A,Lynch JA,Peterfy CG,Nevitt MC,Webb N,Li J,Mohr A,Genant HK,Felson DT

    更新日期:2005-05-01 00:00:00

  • Multiparametric computer-aided differential diagnosis of Alzheimer's disease and frontotemporal dementia using structural and advanced MRI.

    abstract:OBJECTIVES:To investigate the added diagnostic value of arterial spin labelling (ASL) and diffusion tensor imaging (DTI) to structural MRI for computer-aided classification of Alzheimer's disease (AD), frontotemporal dementia (FTD), and controls. METHODS:This retrospective study used MRI data from 24 early-onset AD an...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-016-4691-x

    authors: Bron EE,Smits M,Papma JM,Steketee RME,Meijboom R,de Groot M,van Swieten JC,Niessen WJ,Klein S

    更新日期:2017-08-01 00:00:00

  • Interstitial photodynamic laser therapy in interventional oncology.

    abstract::Photodynamic therapy (PDT) is a well-investigated locoregional cancer treatment in which a systemically administered photosensitizer is activated locally by illuminating the diseased tissue with light of a suitable wavelength. PDT offers various treatment strategies in oncology, especially palliative ones. This articl...

    journal_title:European radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00330-004-2290-8

    authors: Vogl TJ,Eichler K,Mack MG,Zangos S,Herzog C,Thalhammer A,Engelmann K

    更新日期:2004-06-01 00:00:00

  • Assessment of intracardiac flow and vorticity in the right heart of patients after repair of tetralogy of Fallot by flow-sensitive 4D MRI.

    abstract:OBJECTIVES:To comprehensively and quantitatively analyse flow and vorticity in the right heart of patients after repair of tetralogy of Fallot (rTOF) compared with healthy volunteers. METHODS:Time-resolved flow-sensitive 4D MRI was acquired in 24 rTOF patients and 12 volunteers. Qualitative flow evaluation was based o...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-015-4186-1

    authors: Hirtler D,Garcia J,Barker AJ,Geiger J

    更新日期:2016-10-01 00:00:00

  • Expiratory CT in cigarette smokers: correlation between areas of decreased lung attenuation, pulmonary function tests and smoking history.

    abstract::The aim of this study was to determine the correlation between cigarette-smoke-related bronchial disease and air trapping as assessed by expiratory high-resolution CT (HRCT) scans. Thirty healthy subjects (11 non-smokers, 7 ex-smokers for > 2 years, 12 current smokers; age range 35-55 years) with a smoking history bet...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300050558

    authors: Verschakelen JA,Scheinbaum K,Bogaert J,Demedts M,Lacquet LL,Baert AL

    更新日期:1998-01-01 00:00:00

  • Preoperative T staging of gastric carcinoma obtained by MDCT vessel probe reconstructions and correlations with histological findings.

    abstract::This study aims to evaluate the diagnostic accuracy of 16-row multidetector CT (MDCT) and vessel probe reconstructions in the T staging of gastric carcinoma. Fifty-three patients (39 men, 14 women, mean age 57.5) with an endoscopic diagnosis of gastric adenocarcinoma underwent CT examination. A hypotonic drug was admi...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-009-1482-7

    authors: Moschetta M,Stabile Ianora AA,Anglani A,Marzullo A,Scardapane A,Angelelli G

    更新日期:2010-01-01 00:00:00

  • Polyp measurement based on CT colonography and colonoscopy: variability and systematic differences.

    abstract:OBJECTIVE:To assess the variability and systematic differences in polyp measurements on optical colonoscopy and CT colonography. MATERIALS:Gastroenterologists measured 51 polyps by visual estimation, forceps comparison and linear probe. CT colonography observers randomly assessed polyp size two-dimensionally (abdomina...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-009-1683-0

    authors: de Vries AH,Bipat S,Dekker E,Liedenbaum MH,Florie J,Fockens P,van der Kraan R,Mathus-Vliegen EM,Reitsma JB,Truyen R,Vos FM,Zwinderman AH,Stoker J

    更新日期:2010-06-01 00:00:00

  • The accuracy of teleradiologists in diagnosing COVID-19 based on a French multicentric emergency cohort.

    abstract:OBJECTIVES:To evaluate the accuracy of diagnoses of COVID-19 based on chest CT as well as inter-observer agreement between teleradiologists during on-call duty and senior radiologists in suspected COVID-19 patients. MATERIALS AND METHODS:From March 13, 2020, to April 14, 2020, consecutive suspected COVID-19 adult pati...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-020-07345-z

    authors: Nivet H,Crombé A,Schuster P,Ayoub T,Pourriol L,Favard N,Chazot A,Alonzo-Lacroix F,Youssof E,Ben Cheikh A,Balique J,Porta B,Petitpierre F,Bouquet G,Mastier C,Bratan F,Bergerot JF,Thomson V,Banaste N,Gorincour G

    更新日期:2020-10-29 00:00:00

  • Pitfalls and problems to be solved in the diagnostic CT/MRI Liver Imaging Reporting and Data System (LI-RADS).

    abstract::The 2017 Core of the computed tomography (CT)/magnetic resonance imaging (MRI) Liver Imaging Reporting and Data System (LI-RADS) provides clear definitions and concise explanations of the CT/MRI diagnostic algorithm. Nevertheless, there remain some practical and controversial issues that radiologists should be aware o...

    journal_title:European radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00330-018-5641-6

    authors: Kim YY,Choi JY,Sirlin CB,An C,Kim MJ

    更新日期:2019-03-01 00:00:00