Abstract:
:Although multimodality therapy for high-grade gliomas is making some improvement in outcome, most patients will still die from their disease within a short time. We need tools that allow treatments to be tailored to an individual. In this study we used diffusion tensor imaging (DTI), a technique sensitive to subtle disruption of white-matter tracts due to tumour infiltration, to see if it can be used to predict patterns of glioma recurrence. In this study we imaged 26 patients with gliomas using DTI. Patients were imaged after 2 years or on symptomatic tumour recurrence. The diffusion tensor was split into its isotropic (p) and anisotropic (q) components, and these were plotted on T(2)-weighted images to show the pattern of DTI abnormality. This was compared to the pattern of recurrence. Three DTI patterns could be identified: (a) a diffuse pattern of abnormality where p exceeded q in all directions and was associated with diffuse increase in tumour size; (b) a localised pattern of abnormality where the tumour recurred in one particular direction; and (c) a pattern of minimal abnormality seen in some patients with or without evidence of recurrence. Diffusion tensor imaging is able to predict patterns of tumour recurrence and may allow better individualisation of tumour management and stratification for randomised controlled trials.
journal_name
Eur Radioljournal_title
European radiologyauthors
Price SJ,Jena R,Burnet NG,Carpenter TA,Pickard JD,Gillard JHdoi
10.1007/s00330-006-0561-2subject
Has Abstractpub_date
2007-07-01 00:00:00pages
1675-84issue
7eissn
0938-7994issn
1432-1084journal_volume
17pub_type
杂志文章abstract:OBJECTIVES:Cerebral blood flow (CBF) estimates from arterial spin labelling (ASL) show unexplained variability in older populations. We studied the impact of variation of haematocrit (Hct) on CBF estimates in a tri-ethnic elderly population. MATERIALS AND METHODS:Approval for the study was obtained from the Fulham Res...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06096-w
更新日期:2019-10-01 00:00:00
abstract::The aim of our study was to investigate local therapeutic effects and long-term results of combined transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) in the treatment of large hepatocellular carcinoma (HCC). Eight-six patients (67 males and 19 females, age range 48-75 years, mean...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050409
更新日期:1998-01-01 00:00:00
abstract::Magnetic resonance angiography (MRA) has become an imaging modality which comprises various techniques based on two concepts: methods relying on the natural flow effects, the time-of-flight and phase-contrast technique, either in two- or three-dimensional acquisition mode, and the more recently developed contrast-enha...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300050834
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVES:To develop and prospectively validate a novel weighted quantitative scoring system based on CT findings, namely, the renal cyst index (RCI), aimed at preoperatively predicting the pathological features of cystic renal masses (CRMs). METHODS:The RCI was based on four critical features of CRMs: the cyst wall,...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5722-6
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVES:To evaluate the accuracy and reproducibility of semi-quantitative visual assessment of hepatic tumor burden (HTB) on MRI and to investigate its prognostic value in predicting overall survival (OS) in neuroendocrine liver metastases (NELMs) treated with transarterial chemoembolization (TACE). METHODS:Three i...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06246-0
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:To evaluate the accuracy of diagnoses of COVID-19 based on chest CT as well as inter-observer agreement between teleradiologists during on-call duty and senior radiologists in suspected COVID-19 patients. MATERIALS AND METHODS:From March 13, 2020, to April 14, 2020, consecutive suspected COVID-19 adult pati...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07345-z
更新日期:2020-10-29 00:00:00
abstract:OBJECTIVES:Knowledge on the epidemiology and long-term course of rotator cuff calcific tendinitis (RCCT) is scarce. We assessed demographics, radiological characteristics, and their association with long-term outcomes in a large patient group. METHODS:Baseline demographics, radiological characteristics and treatment w...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4224-7
更新日期:2016-10-01 00:00:00
abstract::This review provides an overview of structural magnetic resonance imaging and computed tomography findings of direct and indirect alcohol-related toxic effects on the brain. In addition to ethanol-related changes to the brain, this article will also describe imaging findings in the acute setting of methanol and ethyle...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-009-1668-z
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:Despite 90 % of glioblastoma (GBM) recurrences occurring in the peritumoral brain zone (PBZ), its contribution in patient survival is poorly understood. The current study leverages computerized texture (i.e. radiomic) analysis to evaluate the efficacy of PBZ features from pre-operative MRI in predicting long-...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4637-3
更新日期:2017-10-01 00:00:00
abstract::The aim of this study was to revisit anal anatomy, to explain surgical terminology in perianal complications of Crohn disease, and to show the MR imaging findings of perianal fistulas and abscesses. To this end more than 200 patients were studied using surface coils (Helmholtz; phased array) at 1.0 and 1.5 T. Transver...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050248
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVES:The purpose of our study was to assess whether there is a potential additional value of real-time virtual sonography (RVS) to second-look ultrasound (US) examination and biopsy for breast lesions identified on MRI alone. METHODS:A retrospective review of the records of 70 consecutive patients (78 lesions) w...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-015-3892-z
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:It is controversial to adopt non-invasive diagnostic criteria of hepatocellular carcinoma (HCC) in subcentimeter lesions. This study was aimed to define the optimal noninvasive diagnostic criteria of subcentimeter HCC and to evaluate the effect on tumor staging. METHODS:We included 110 treatment-naïve patien...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07329-z
更新日期:2020-10-12 00:00:00
abstract:OBJECTIVES:Radiographs are often performed to assess pelvic and hip parameters, but results depend upon correct pelvis positioning. Three-dimensional (3D) reconstruction from biplanar-radiographs should provide parameters that are less sensitive to pelvic orientation, but this remained to be evaluated. METHODS:Compute...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4452-x
更新日期:2017-03-01 00:00:00
abstract:PURPOSE:To evaluate the inter-/intra-observer agreement of BI-RADS-based subjective visual estimation of the amount of fibroglandular tissue (FGT) with magnetic resonance imaging (MRI), and to investigate whether FGT assessment benefits from an automated, observer-independent, quantitative MRI measurement by comparing ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-016-4274-x
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVES:To evaluate an image-navigated isotropic high-resolution 3D late gadolinium enhancement (LGE) prototype sequence with compressed sensing and Dixon water-fat separation in a clinical routine setting. MATERIAL AND METHODS:Forty consecutive patients scheduled for cardiac MRI were enrolled prospectively and exa...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-020-07517-x
更新日期:2020-12-02 00:00:00
abstract:OBJECTIVES:To evaluate post-ablation MRI for the detection of incompletely treated spinal osseous metastases (SOM) after cryoablation and to propose a post-ablation imaging classification. METHODS:After IRB consent, all patients treated with cryoablation of SOM between 2011 and 2017 having at least 1-year minimum foll...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06040-y
更新日期:2019-10-01 00:00:00
abstract::Bronchioloalveolar carcinoma (BAC) is a polymorphic lung cancer the incidence of which is rising. The presence of intratumoral radiolucencies is an important feature of bronchioloalveolar carcinoma. The aim of this study was to present pictorially the spectrum of intratumoral radiolucencies visible in BAC. In 57 BACs ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050627
更新日期:1999-01-01 00:00:00
abstract::To determine whether neutral contrast agents with water-equivalent intraluminal attenuation can improve delineation of the bowel wall and increase overall image quality for a non-selected patient population, a neutral oral contrast agent (3% mannitol) was administered to 100 patients referred for abdominal multidetect...
journal_title:European radiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00330-008-0958-1
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVES:To evaluate the feasibility, image quality and radiation dose of prospectively ECG-triggered high-pitch coronary CT angiography (CCTA) with 30 mL contrast agent at 70 kVp. METHODS:Fifty-eight patients with suspected coronary artery disease, a body mass index (BMI) of less than 25 kg/m(2), sinus rhythm and a...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3157-2
更新日期:2014-07-01 00:00:00
abstract::The magnetic resonance (MR) guidance of endovascular interventions is probably one of the greatest challenges of clinical MR research. MR angiography is not only an imaging tool for the vasculature but can also simultaneously depict high tissue contrast, including the differentiation of the vascular wall and perivascu...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-007-0818-4
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:To assess the relationship between MRI-derived changes in whole-brain and ventricular volume with change in cognitive scores in Alzheimer's disease (AD), mild cognitive impairment (MCI) and control subjects. MATERIAL AND METHODS:In total 131 control, 231 MCI and 99 AD subjects from the Alzheimer's Disease Ne...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-009-1581-5
更新日期:2010-03-01 00:00:00
abstract::The peritoneum is a mesothelial lining of the abdominal cavity (parietal) and intraperitoneal viscera (visceral). The cavity contains a small amount of fluid, which circulates from cephalad to caudal to cephalad, influenced by negative pressure under the diaphragm during exhalation, gravity, and bowel peristalsis. Per...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s003300100998
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:To design clear guidelines for the staging and follow-up of patients with uterine cervical cancer, and to provide the radiologist with a framework for use in multidisciplinary conferences. METHODS:Guidelines for uterine cervical cancer staging and follow-up were defined by the female imaging subcommittee of ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-1998-x
更新日期:2011-05-01 00:00:00
abstract::Many disease processes manifest either primarily or secondarily by cranial nerve deficits. Neurologists, ENT surgeons, ophthalmologists and maxillo-facial surgeons are often confronted with patients with symptoms and signs of cranial nerve dysfunction. Seeking the cause of this dysfunction is a common indication for i...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-006-0575-9
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVES:In dual-source CT, dual-energy (DE) performance is affected by various X-ray tube voltage combinations with and without tin filter (Sn). The purpose of this study was to assess the utility of the 80/150 Sn kV voltage combination in terms of image artefact and radiation dose for DECT gout protocol, compared w...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-018-5622-9
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to evaluate the effect of bilateral salpingo-oophorectomy (BSO) on background parenchymal enhancement (BPE) and the amount of fibroglandular tissue (FGT) seen on breast MRI. METHODS:Retrospective review identified 21 BRCA mutation carriers who underwent breast MRI before and a...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-013-2993-9
更新日期:2014-01-01 00:00:00
abstract::The aim of this study was to assess cross-sectional imaging features and the value of CT and MRI in primary hemangiopericytoma of bone. In five patients with histologically proven primary osseous hemangiopericytoma CT and MR scans were evaluated retrospectively. Both CT and MRI were available in four patients each. In...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300101027
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:To assess the accuracy, the duration and factors that influence the duration of MRI-guided liver or soft-tissue biopsies. METHODS:Nineteen liver biopsies and 19 soft-tissue biopsies performed using 1.5T-MRI guidance were retrospectively analysed. Diagnostic performance and complications were assessed. Interv...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-011-2297-x
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:To assess severity and factors of pain during high-intensity focused ultrasound (HIFU) ablation of benign thyroid nodules. METHODS:128 patients who underwent a HIFU ablation for a benign thyroid nodule were analysed. All patients received a bolus of intravenous pethidine and diazepam before treatment. After ...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-5200-6
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVES:To explore and evaluate the feasibility of radiomics in stratifying nasopharyngeal carcinoma (NPC) into distinct survival subgroups through multi-modalities MRI. METHODS:A total of 658 patients (training cohort: 424; validation cohort: 234) with non-metastatic NPC were enrolled in the retrospective analysis...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-019-06075-1
更新日期:2019-10-01 00:00:00