Volume changes in Alzheimer's disease and mild cognitive impairment: cognitive associations.

Abstract:

OBJECTIVE:To assess the relationship between MRI-derived changes in whole-brain and ventricular volume with change in cognitive scores in Alzheimer's disease (AD), mild cognitive impairment (MCI) and control subjects. MATERIAL AND METHODS:In total 131 control, 231 MCI and 99 AD subjects from the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort with T1-weighted volumetric MRIs from baseline and 12-month follow-up were used to derive volume changes. Mini mental state examination (MMSE), Alzheimer's disease assessment scale (ADAS)-cog and trails test changes were calculated over the same period. RESULTS:Brain atrophy rates and ventricular enlargement differed between subject groups (p < 0.0005) and in MCI and AD were associated with MMSE changes. Both measures were additionally associated with ADAS-cog and trails-B in MCI patients, and ventricular expansion was associated with ADAS-cog in AD patients. Brain atrophy (p < 0.0005) and ventricular expansion rates (p = 0.001) were higher in MCI subjects who progressed to AD within 12 months of follow-up compared with MCI subjects who remained stable. MCI subjects who progressed to AD within 12 months had similar atrophy rates to AD subjects. CONCLUSION:Whole-brain atrophy rates and ventricular enlargement differed between patient groups and healthy controls, and tracked disease progression and psychological decline, demonstrating their relevance as biomarkers.

journal_name

Eur Radiol

journal_title

European radiology

authors

Evans MC,Barnes J,Nielsen C,Kim LG,Clegg SL,Blair M,Leung KK,Douiri A,Boyes RG,Ourselin S,Fox NC,Alzheimer's Disease Neuroimaging Initiative.

doi

10.1007/s00330-009-1581-5

subject

Has Abstract

pub_date

2010-03-01 00:00:00

pages

674-82

issue

3

eissn

0938-7994

issn

1432-1084

journal_volume

20

pub_type

杂志文章
  • Contrast enhancement for the abdomen and pelvis.

    abstract::A "quadraphasic" imaging technique is described for imaging malignancies of the abdomen (liver, kidneys and pancreas). With this technique images are acquired during four different phases relative to the administration of contrast agent: pre-contrast (baseline), during the capillary (arterial, pre-sinusoidal) phase, d...

    journal_title:European radiology

    pub_type: 杂志文章,评审

    doi:10.1007/pl00006899

    authors: Mitchell DG

    更新日期:1997-01-01 00:00:00

  • Comparison of volumetric and functional parameters in simultaneous cardiac PET/MR: feasibility of volumetric assessment with residual activity from prior PET/CT.

    abstract:OBJECTIVE:To compare cardiac left ventricular (LV) parameters in simultaneously acquired hybrid fluorine-18-fluorodeoxyglucose ([18F] FDG) positron emission tomography/magnetic resonance imaging (PET/MRI) in patients with residual tracer activity of upstream PET/CT. METHODS:Twenty-nine patients (23 men, age 58±17 year...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-017-4896-7

    authors: Lücke C,Oppolzer B,Werner P,Foldyna B,Lurz P,Jochimsen T,Brenneis B,Lehmkuhl L,Sattler B,Grothoff M,Barthel H,Sabri O,Gutberlet M

    更新日期:2017-12-01 00:00:00

  • Intramural leiomyoma of the bladder.

    abstract::Mesodermal tumors of the urinary bladder are rare and the majority of them are malignant. We report a case of an intramural leiomyoma of the bladder presenting with symptoms of a mild lower urinary tract infection. The patient was managed with partial cystectomy and the outcome was excellent. ...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300051034

    authors: Sakellariou P,Protopapas A,Kyritsis N,Voulgaris Z,Papaspirou E,Diakomanolis E

    更新日期:2000-01-01 00:00:00

  • Volume estimation of extensor muscles of the lower leg based on MR imaging.

    abstract::Magnetic resonance imaging can be used to measure the muscle volume of a given muscle or muscle group. The purpose of this study was to determine both the intra- and inter-observer variation of the manually outlined volume of the extensor muscles (tibialis anterior, extensor digitorum longus and extensor hallucis long...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-002-1334-1

    authors: Lund H,Christensen L,Savnik A,Boesen J,Danneskiold-Samsøe B,Bliddal H

    更新日期:2002-12-01 00:00:00

  • Functional diagnosis of placenta accreta by intravoxel incoherent motion model diffusion-weighted imaging.

    abstract:OBJECTIVES:To investigate the diagnostic value of intravoxel incoherent motion (IVIM) DWI for placenta accreta by comparing diffusion and perfusion characteristics of placentas with accreta lesions (APs) with those of normal placentas (NPs). METHODS:Twenty-five pregnant women with AP and 24 with NP underwent 3-T magne...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-020-07200-1

    authors: Bao Y,Pang Y,Sun Z,Li Q,Tang D,Xia L

    更新日期:2021-02-01 00:00:00

  • Magnetic resonance imaging of the fetal lung: a pictorial essay.

    abstract::Ultrasound, which is now a widely available and generally accepted, low-cost technique with real-time properties, is the screening investigation of choice in fetal medicine. However, enthusiasm for fetal prenatal magnetic resonance imaging (MRI) is rising, because of the absence of known biological risks, the increasi...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-008-0877-1

    authors: Cannie M,Jani J,De Keyzer F,Van Kerkhove F,Meersschaert J,Lewi L,Deprest J,Dymarkowski S

    更新日期:2008-07-01 00:00:00

  • Value of bone suppression software in chest radiographs for improving image quality and reducing radiation dose.

    abstract:OBJECTIVES:To compare image quality and radiation dose between dual-energy subtraction (DES)-based bone suppression images (D-BSIs) and software-based bone suppression images (S-BSIs). METHODS:Chest radiographs (CXRs) of forty adult patients were obtained with the two X-ray devices, one with DES and one with bone supp...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-020-07596-w

    authors: Hong GS,Do KH,Son AY,Jo KW,Kim KP,Yun J,Lee CW

    更新日期:2021-01-13 00:00:00

  • A New Model for MR Evaluation of Liver Function with Gadoxetic Acid, Including Both Uptake and Excretion.

    abstract:OBJECTIVES:Most existing models that are in use to model hepatic function through assessment of hepatic gadoxetic acid enhancement kinetics do not consider quantitative measures of gadoxetic excretion. We developed a model that allows a simultaneous quantitation of uptake and excretion of liver specific contrast agents...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-018-5500-5

    authors: Truhn D,Kuhl CK,Ciritsis A,Barabasch A,Kraemer NA

    更新日期:2019-01-01 00:00:00

  • Direct magnetic resonance arthrography.

    abstract::Magnetic resonance (MR) arthrography has gained increasing popularity as a diagnostic tool in the assessment of intra-articular derangements. Its role has been studied extensively in the shoulder, but it also has been explored in the hip, elbow, knee, wrist and ankle. This article reviews the current role of direct MR...

    journal_title:European radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00330-004-2449-3

    authors: Elentuck D,Palmer WE

    更新日期:2004-11-01 00:00:00

  • Breast augmentation and reconstructive surgery: MR imaging of implant rupture and malignancy.

    abstract::The purpose of this study was to assess the diagnostic accuracy of MRI in detecting prosthesis integrity and malignancy after breast augmentation and reconstruction. Forty-one implants in 25 patients were analyzed by MRI before surgical removal. Imaging results were compared with ex vivo findings. Magnetic resonance i...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-002-1362-x

    authors: Herborn CU,Marincek B,Erfmann D,Meuli-Simmen C,Wedler V,Bode-Lesniewska B,Kubik-Huch RA

    更新日期:2002-09-01 00:00:00

  • Evaluation of a semiautomatic software tool for left ventricular function analysis with 16-slice computed tomography.

    abstract::The purpose of the study was to evaluate a semiautomatic analysis tool for assessing global left ventricular myocardial function with multislice computed tomography (MSCT). We examined 33 patients with MSCT using 16x0.5 mm detector collimation and magnetic resonance imaging (MRI) on a 1.5-T scanner. MSCT data were ana...

    journal_title:European radiology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00330-005-2817-7

    authors: Dewey M,Müller M,Teige F,Hamm B

    更新日期:2006-01-01 00:00:00

  • Ultrasound features of malignancy in the preoperative diagnosis of parathyroid cancer: a retrospective analysis of parathyroid tumours larger than 15 mm.

    abstract:OBJECTIVE:Nearly all reported parathyroid cancers are >15 mm at presentation. The objective was to identify ultrasound criteria of malignancy in parathyroid lesions of >15 mm in size. MATERIALS AND METHODS:This study was approved by a local ethics committee. A retrospective review of patients identified from a databas...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-011-2141-3

    authors: Sidhu PS,Talat N,Patel P,Mulholland NJ,Schulte KM

    更新日期:2011-09-01 00:00:00

  • Delayed enhancement imaging of myocardial viability: low-dose high-pitch CT versus MRI.

    abstract:OBJECTIVES:To evaluate the accuracy of high-pitch delayed enhancement (DE) CT for the assessment of myocardial viability with MRI as the reference standard. METHODS:Twenty-four patients (mean age 66.9 ± 9.2 years) with coronary artery disease underwent DE imaging with 128-slice dual-source CT (prospective electrocardi...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-011-2149-8

    authors: Goetti R,Feuchtner G,Stolzmann P,Donati OF,Wieser M,Plass A,Frauenfelder T,Leschka S,Alkadhi H

    更新日期:2011-10-01 00:00:00

  • Post-imaging pulmonary nodule mathematical prediction models: are they clinically relevant?

    abstract:OBJECTIVES:Post-imaging mathematical prediction models (MPMs) provide guidance for the management of solid pulmonary nodules by providing a lung cancer risk score from demographic and radiologists-indicated imaging characteristics. We hypothesized calibrating the MPM risk score threshold to a local study cohort would r...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-019-06168-x

    authors: Uthoff J,Koehn N,Larson J,Dilger SKN,Hammond E,Schwartz A,Mullan B,Sanchez R,Hoffman RM,Sieren JC,COPDGene Investigators.

    更新日期:2019-10-01 00:00:00

  • Novel technique for addressing streak artifact in gated dual-source MDCT angiography utilizing ECG-editing.

    abstract::Streak artifact is an important source of image degradation in computed tomographic imaging. In coronary MDCT angiography, streak artifact from pacemaker leads in the SVC can render segments of the right coronary artery uninterpretable. With current technology in clinical practice, there is no effective way to elimina...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-008-1013-y

    authors: Meyer LT,Boll DT

    更新日期:2008-11-01 00:00:00

  • The correlation of mammographic-and histologic patterns of breast cancers in BRCA1 gene mutation carriers, compared to age-matched sporadic controls.

    abstract::Breast cancers in BRCA1 gene mutation carriers often have specific histologic features: grade III tumors with pushing margins. Our purpose was to compare the mammographic and histologic features of breast cancers in carriers with those in age-matched sporadic controls. The features of breast cancers in 27 BRCA1 carrie...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-006-0385-0

    authors: Kaas R,Kroger R,Peterse JL,Hart AA,Muller SH

    更新日期:2006-12-01 00:00:00

  • Quantitative assessment of terminal ileum motility on MR enterography in Crohn disease: a feasibility study in children.

    abstract:OBJECTIVES:Investigate the relationship between quantified terminal ileal (TI) motility and histopathological activity grading, Crohn Disease MRI Index (CDMI) and faecal calprotectin. METHODS:Retrospective review of children with Crohn disease or unclassified inflammatory bowel disease, who underwent MR enterography. ...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-020-07084-1

    authors: Cococcioni L,Fitzke H,Menys A,Gaunt T,Kumar S,Kiparissi F,Rampling D,Palm L,Taylor SA,Watson TA

    更新日期:2021-02-01 00:00:00

  • Proper timing for the evaluation of neonatal brain white matter development: a diffusion tensor imaging study.

    abstract:OBJECTIVE:We aimed to determine the timing for assessing birth status of the developing brain (i.e. brain maturity at birth) by exploring the postnatal age-related changes in neonatal brain white matter (WM). METHODS:The institutional review board approved this study and all informed parental consents were obtained. 1...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-018-5665-y

    authors: Jin C,Li Y,Li X,Wang M,Liu C,Gao J,Sun Q,Qiu D,Zeng L,Zhou X,Li G,Zhang J,Zheng J,Yang J

    更新日期:2019-03-01 00:00:00

  • Significant differences when using MDRD for GFR estimation compared to radionuclide measured clearance.

    abstract:OBJECTIVES:To evaluate Estimated Glomerular Filtration Rate (eGFR), using the Modification of Diet in Renal Disease equation, and compare with radionuclide GFR (rGFR) in a Radiology setting to assess renal function prior to contrast administration. METHODS:Five hundred and sixteen retrospective rGFR studies from a mix...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-011-2157-8

    authors: Craig AJ,Britten A,Heenan SD,Irwin AG

    更新日期:2011-10-01 00:00:00

  • Lymphoma: pictorial review. I.

    abstract::Lymphoma is a spectrum of malignant neoplasms of the lymphoid system. The appearances radiologically are diverse with almost all organs susceptible to involvement. The condition is challenging as it can mimic the appearance of almost all other neoplasms. This review highlights in a general way the diversity of the rad...

    journal_title:European radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00330-002-1632-7

    authors: Halliday T,Baxter G

    更新日期:2003-05-01 00:00:00

  • Differentiation between primary CNS lymphoma and glioblastoma: qualitative and quantitative analysis using arterial spin labeling MR imaging.

    abstract:OBJECTIVES:To evaluate the diagnostic performance of arterial spin labelling perfusion weighted images (ASL-PWIs) to differentiate primary CNS lymphoma (PCNSL) from glioblastoma (GBM). METHODS:ASL-PWIs of pathologically confirmed PCNSL (n = 21) or GBM (n = 93) were analysed. For qualitative analysis, tumours were visu...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-018-5359-5

    authors: You SH,Yun TJ,Choi HJ,Yoo RE,Kang KM,Choi SH,Kim JH,Sohn CH

    更新日期:2018-09-01 00:00:00

  • Using coronary CT angiography for guiding invasive coronary angiography: potential role to reduce intraprocedural radiation exposure.

    abstract:OBJECTIVES:We investigated the potential reduction of patient exposure during invasive coronary angiography (ICA) if the procedure had only been directed to the vessel with at least one ≥ 50% stenosis as described in the CT report. METHODS:Dose reports of 61 patients referred to ICA because of at least one ≥ 50% steno...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-018-5317-2

    authors: Arendt CT,Tischendorf P,Wichmann JL,Messerli M,Jörg L,Ehl N,Gohmann RF,Wildermuth S,Vogl TJ,Bauer RW

    更新日期:2018-07-01 00:00:00

  • Advances in ultrasound.

    abstract::Significant advances have been recently introduced into various fields of technology, taking advantage of the use of new piezoelectric materials and the large diffusion of broadband transducers. Various types of modulation may be applied to the pulse characteristics, using single pulse, multipulse or multiline techniq...

    journal_title:European radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00330-001-1185-1

    authors: Claudon M,Tranquart F,Evans DH,Lefèvre F,Correas M

    更新日期:2002-01-01 00:00:00

  • Assessment of intracardiac flow and vorticity in the right heart of patients after repair of tetralogy of Fallot by flow-sensitive 4D MRI.

    abstract:OBJECTIVES:To comprehensively and quantitatively analyse flow and vorticity in the right heart of patients after repair of tetralogy of Fallot (rTOF) compared with healthy volunteers. METHODS:Time-resolved flow-sensitive 4D MRI was acquired in 24 rTOF patients and 12 volunteers. Qualitative flow evaluation was based o...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-015-4186-1

    authors: Hirtler D,Garcia J,Barker AJ,Geiger J

    更新日期:2016-10-01 00:00:00

  • The MR radiomic signature can predict preoperative lymph node metastasis in patients with esophageal cancer.

    abstract:PURPOSE:To assess the role of the MR radiomic signature in preoperative prediction of lymph node (LN) metastasis in patients with esophageal cancer (EC). PATIENTS AND METHODS:A total of 181 EC patients were enrolled in this study between April 2015 and September 2017. Their LN metastases were pathologically confirmed....

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-018-5583-z

    authors: Qu J,Shen C,Qin J,Wang Z,Liu Z,Guo J,Zhang H,Gao P,Bei T,Wang Y,Liu H,Kamel IR,Tian J,Li H

    更新日期:2019-02-01 00:00:00

  • Effect of hybrid iterative reconstruction technique on quantitative and qualitative image analysis at 256-slice prospective gating cardiac CT.

    abstract:OBJECTIVES:To evaluate the effect of hybrid iterative reconstruction on qualitative and quantitative parameters at 256-slice cardiac CT. METHODS:Prospective cardiac CT images from 20 patients were analysed. Paired image sets were created using 3 reconstructions, i.e. filtered back projection (FBP) and moderate- and hi...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-011-2361-6

    authors: Utsunomiya D,Weigold WG,Weissman G,Taylor AJ

    更新日期:2012-06-01 00:00:00

  • Fine needle aspiration biopsy indications for thyroid nodules: compare a point-based risk stratification system with a pattern-based risk stratification system.

    abstract:OBJECTIVES:We aim to compare the diagnostic performance to assess thyroid nodules and reliability for recommending fine needle aspiration biopsy (FNAB) between American College of Radiology thyroid image reporting and data system (ACR TI-RADS) and American Thyroid Association (ATA) guidelines. METHODS:In total, this r...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-018-5992-z

    authors: Ruan JL,Yang HY,Liu RB,Liang M,Han P,Xu XL,Luo BM

    更新日期:2019-09-01 00:00:00

  • Thread sign in biliary intraductal papillary mucinous neoplasm: a novel specific finding for MRI.

    abstract:OBJECTIVES:To evaluate thread sign of biliary intraductal papillary mucinous neoplasm (B-IPMN) on magnetic resonance imaging (MRI). METHODS:Thread sign was defined as intraductal linear or curvilinear hypointense striations. Two radiologists independently evaluated the presence and location of thread sign on MR cholan...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-015-4158-5

    authors: Hong GS,Byun JH,Kim JH,Kim HJ,Lee SS,Hong SM,Lee MG

    更新日期:2016-09-01 00:00:00

  • Long-term results of percutaneous ethanol injection therapy for hepatocellular carcinoma in cirrhosis: a European experience.

    abstract::The objective of our work was to evaluate the long-term results of percutaneous ethanol injection (PEI) for the treatment of hepatocellular carcinoma (HCC) in patients with liver cirrhosis. A total of 184 cirrhotic patients with HCC underwent PEI as the only anticancer treatment over an 8-year period. Patients were fo...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s003300050194

    authors: Lencioni R,Pinto F,Armillotta N,Bassi AM,Moretti M,Di Giulio M,Marchi S,Uliana M,Della Capanna S,Lencioni M,Bartolozzi C

    更新日期:1997-01-01 00:00:00

  • Congenital anorectal atresia: MR imaging of late post-operative appearances in adult patients with anal incontinence.

    abstract:OBJECTIVES:To describe the MR imaging findings in adults presenting with anal incontinence following pull-through perineoplasty for anorectal atresia. METHODS:15 adults (12 male, 3 female; age 22-52 years) with anal incontinence following a prior perineal pull-through procedure as an infant for anorectal atresia were ...

    journal_title:European radiology

    pub_type: 杂志文章

    doi:10.1007/s00330-013-2949-0

    authors: Gartner L,Peiris C,Marshall M,Taylor SA,Halligan S

    更新日期:2013-12-01 00:00:00