Abstract：
:Breast cancers in BRCA1 gene mutation carriers often have specific histologic features: grade III tumors with pushing margins. Our purpose was to compare the mammographic and histologic features of breast cancers in carriers with those in age-matched sporadic controls. The features of breast cancers in 27 BRCA1 carriers found during annual surveillance were compared to those in 107 age-matched sporadic controls. The carriers had no (classic) spiculated mammographic lesions, a high percentage of well-defined masses and hardly any masses with microcalcifications, whereas the controls had significantly fewer well-defined ones and only in 27% spiculated lesions on the mammogram. The well-defined mammographic tumors correlated in 83% of the carriers and in 70% of the controls with histologic circumscribed tumor margins. Spiculated mammographic lesions in the controls were in 90% grade I or II tumors. DCIS with or without infiltration was seen in 22% of the carriers and in 45% of the controls. In conclusion, breast cancers diagnosed in BRCA1 carriers do not have classic malignant mammographic features. A minority of the young sporadic controls show the classic malignant lesion on the mammogram. Both carriers and controls generally show a good correlation between their mammographic- and histologic tumor pattern.
journal_name
Eur Radioljournal_title
European radiologyauthors
Kaas R,Kroger R,Peterse JL,Hart AA,Muller SHdoi
10.1007/s00330-006-0385-0subject
Has Abstractpub_date
2006-12-01 00:00:00pages
2842-8issue
12eissn
0938-7994issn
1432-1084journal_volume
16pub_type
杂志文章abstract：OBJECTIVE:Nearly all reported parathyroid cancers are >15 mm at presentation. The objective was to identify ultrasound criteria of malignancy in parathyroid lesions of >15 mm in size. MATERIALS AND METHODS:This study was approved by a local ethics committee. A retrospective review of patients identified from a databas...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-011-2141-3
更新日期：2011-09-01 00:00:00
abstract：:To overcome the limitations of the classical volume scoring method for quantifying coronary calcifications, including accuracy, variability between examinations, and dependency on plaque density and acquisition parameters, a mesh-based volume measurement method has been developed. It was evaluated and compared with th...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-008-1181-9
更新日期：2009-03-01 00:00:00
abstract：OBJECTIVE:To design clear guidelines for the staging and follow-up of patients with uterine cervical cancer, and to provide the radiologist with a framework for use in multidisciplinary conferences. METHODS:Guidelines for uterine cervical cancer staging and follow-up were defined by the female imaging subcommittee of ...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-010-1998-x
更新日期：2011-05-01 00:00:00
abstract：OBJECTIVES:To assess whether contralateral parenchymal enhancement reproduces as an independent biomarker for patient survival in an independent patient cohort from a different cancer institution. METHODS:This is a HIPAA-compliant IRB approved retrospective study. Patients with ER-positive/HER2-negative operable invas...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-018-5470-7
更新日期：2018-11-01 00:00:00
abstract：:Axillary management in patients with breast cancer has become much less invasive with the introduction of sentinel lymph node biopsy (SLNB). However, over 70 % of SLNBs are negative, questioning the generic use of this invasive procedure. Emerging evidence indicates that breast cancer patients with a low axillary burd...
journal_title：European radiology
pub_type： 杂志文章,评审
doi：10.1007/s00330-013-3009-5
更新日期：2014-02-01 00:00:00
abstract：:The objective of this study was to optimize ankle joint MR imaging in volunteers at 1.5 Tesla (T) and 3.0 T, and to compare these optimized sequences concerning image quality and performance in assessing cartilage, ligament and tendon pathology in fresh human cadaver specimens. Initially our clinical ankle protocol co...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-006-0446-4
更新日期：2007-06-01 00:00:00
abstract：OBJECTIVES:Pre-therapeutic prediction of outcome is important for clinicians and patients in determining whether selective internal radiation therapy (SIRT) is indicated for hepatic metastases of colorectal cancer (CRC). METHODS:Pre-therapeutic characteristics of 100 patients with colorectal liver metastases (CRLM) tr...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-015-3658-7
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVES:To evaluate a whole body (WB) continuous-table-movement (CTM) MR protocol for the assessment of multiple myeloma (MM) in comparison to a step-by-step WB protocol. METHODS:Eighteen patients with MM were examined at 1.5T using a WB CTM protocol (axial T2-w fs BLADE, T1-w GRE sequence) and a step-by-step WB pr...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-010-1865-9
更新日期：2010-12-01 00:00:00
abstract：:Intraventricular tumours represent a diverse group of lesions, some of them infrequent, with a wide variety of radiological features. Determination of their precise aetiology or origin can be difficult. Nevertheless, considering patient's age, location within the ventricles, and some specific radiological features, th...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s003300051044
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVES:To evaluate the safety and efficacy of iopentol 350 mg I/ml (Imagopaque/Ivépaque, Nycomed Imaging AS, Oslo, Norway), a monomeric non-ionic contrast medium for computed tomography, in a large population. To identify predictive factors for patient safety. MATERIALS AND METHODS:One thousand eight hundred and t...
journal_title：European radiology
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1007/pl00006874
更新日期：1997-01-01 00:00:00
abstract：OBJECTIVES:To demonstrate the feasibility of using chemical exchange saturation transfer (CEST) imaging to detect Parkinson's disease (PD) in patients at 3 Tesla. METHODS:Twenty-seven PD patients (17 men and 10 women; age range, 54-77 years) and 22 age-matched normal controls (13 men and 9 women; age range, 55-73 year...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-014-3241-7
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVES:Most existing models that are in use to model hepatic function through assessment of hepatic gadoxetic acid enhancement kinetics do not consider quantitative measures of gadoxetic excretion. We developed a model that allows a simultaneous quantitation of uptake and excretion of liver specific contrast agents...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-018-5500-5
更新日期：2019-01-01 00:00:00
abstract：INTRODUCTION:The aim of the study was to extract anthropometric measures from CT by deep learning and to evaluate their prognostic value in patients with non-small-cell lung cancer (NSCLC). METHODS:A convolutional neural network was trained to perform automatic segmentation of subcutaneous adipose tissue (SAT), viscer...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-019-06630-w
更新日期：2020-06-01 00:00:00
abstract：OBJECTIVES:To assess whether extracellular volume (ECV) fraction with equilibrium contrast-enhanced multidetector computed tomography (MDCT) predicts outcomes for unresectable pancreatic adenocarcinoma patients treated with chemotherapy METHODS: Sixty-seven patients (42 men, 25 women; mean age, 67.5 years; range, 45-83...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-018-5570-4
更新日期：2019-01-01 00:00:00
abstract：:Both multislice computed tomography (CT) and magnetic resonance imaging (MRI) are emerging as methods to detect coronary artery stenoses and assess cardiac function and morphology. Non-cardiac structures are also amenable to assessment by these non-invasive tests. We investigated the rate of significant and insignific...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-006-0570-1
更新日期：2007-08-01 00:00:00
abstract：:The purpose was to evaluate the accuracy of multidetector CT (MDCT) on a 16-row CT scanner in local staging of endometrial carcinoma and more specifically in the assessment of the depth of myometrial invasion and presence of cervical infiltration. This prospective study includes 21 women with newly diagnosed endometri...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-007-0839-z
更新日期：2008-05-01 00:00:00
abstract：:The peritoneum is the largest and most complexly arranged serous membrane in the body. The potential peritoneal spaces, the peritoneal reflections forming peritoneal ligaments, mesenteries, omenta and the natural flow of peritoneal fluid determine the route of spread of intraperitoneal fluid and, consequently, disease...
journal_title：European radiology
pub_type： 杂志文章,评审
doi：10.1007/s003300050485
更新日期：1998-01-01 00:00:00
abstract：:The appearances of knee injuries on MR imaging are less well documented in children than adults. Some patterns of injury are shared by both groups of patients, e. g. meniscal damage. The frequency of specific injuries may differ, e. g. anterior cruciate ligament (ACL) tear. Congenital abnormality, coexistent pathology...
journal_title：European radiology
pub_type： 杂志文章,评审
doi：10.1007/s003300050284
更新日期：1997-01-01 00:00:00
abstract：:The aim of this study was to assess the interobserver variations in diagnosis of pulmonary embolism (PE) with cine technique and to compare the diagnostic accuracy of pulmonary arteriograms to final-outcome diagnosis. One hundred and seventy patients with clinical suspicion of acute PE were examined with ECG, laborato...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s003300050667
更新日期：1999-01-01 00:00:00
abstract：:The differentiation of hemangioma from other hepatic neoplasms using MRI usually relies on the evaluation of heavily T2-weighted images. The aim of this study was to assess the value of T2-relaxation times calculated from moderately T2-weighted turbo spin-echo (TSE) sequence in characterization of focal hepatic lesion...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-002-1366-6
更新日期：2002-09-01 00:00:00
abstract：OBJECTIVES:To evaluate the diagnostic performance of shear-wave elastography (SWE) for breast cancer and to determine whether the integration of SWE into BI-RADS with subcategories of category 4 improves the diagnostic performance. METHODS:A total of 389 breast masses (malignant 120, benign 269) in 324 women who under...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-013-2873-3
更新日期：2013-10-01 00:00:00
abstract：OBJECTIVE:To determine the possible influence of segmentation margin on each step (feature reproducibility, selection, and classification) of the machine learning (ML)-based high-dimensional quantitative computed tomography (CT) texture analysis (qCT-TA) of renal clear cell carcinomas (RcCCs). MATERIALS AND METHODS:Fo...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-019-6003-8
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:To determine the diagnostic accuracy of diffusion-weighted (DW) magnetic resonance (MR) imaging in the preoperative assessment of myometrial invasion by endometrial cancer. MATERIALS AND METHODS:In this prospective study, 47 patients with histologically confirmed endometrial cancer underwent preoperative MR ...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-009-1597-x
更新日期：2010-03-01 00:00:00
abstract：:The technique of thrombolysis is now well established, becoming employed increasingly often in disease of the peripheral vasculature, both arterial and venous, in addition to its important role in the treatment of coronary artery thrombosis. This is a general review of its applications in peripheral vascular disease c...
journal_title：European radiology
pub_type： 杂志文章,评审
doi：10.1007/s003300000705
更新日期：2001-01-01 00:00:00
abstract：:Diagnosis of myocardial viability after infarction focuses on the prediction of functional improvement of dysfunctional myocardium after revascularization therapy. Magnetic resonance imaging provides different approaches for the detection of myocardial viability. Measurement of end-diastolic wall thickness is easy to ...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-002-1701-y
更新日期：2003-01-01 00:00:00
abstract：:In western European countries most blunt chest traumas are associated with motor vehicle and sport-related accidents. In Switzerland, 39 of 10,000 inhabitants were involved and severely injured in road accidents in 1998. Fifty two percent of them suffered from blunt chest trauma. According to the Swiss Federal Office ...
journal_title：European radiology
pub_type： 杂志文章,评审
doi：10.1007/s003300000435
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVES:Evaluation of enhancement characteristics of histopathologically confirmed focal nodular hyperplasias (FNHs) and hepatocellular adenomas (HCAs) with gadoxetic acid-enhanced MRI. METHODS:Sixty-eight patients with 115 histopathologically proven lesions (FNHs, n=44; HCAs, n=71) examined with gadoxetic acid-enh...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-014-3144-7
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVES:To compare 0.15 mmol/kg gadobutrol for late gadolinium enhancement (LGE) imaging of chronic myocardial infarction with a relaxivity-adjusted dose of gadoterate meglumine (Gd-DOTA). METHODS:Seventeen patients with suspected chronic myocardial infarction underwent LGE imaging at 1.5 T, acquiring an inversion-...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-012-2563-6
更新日期：2013-01-01 00:00:00
abstract：:Placenta percreta is a potentially life-threatening complication of pregnancy, which is increasing in incidence. Ante-natal diagnosis with ultrasound and magnetic resonance imaging aids the obstetric team in planning further management. We present a case of placenta percreta with imaging and a brief review of the lite...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-006-0498-5
更新日期：2007-06-01 00:00:00
abstract：OBJECTIVES:To identify and evaluate profiles of US and CT features associated with acute appendicitis. METHODS:Consecutive patients presenting with acute abdominal pain at the emergency department were invited to participate in this study. All patients underwent US and CT. Imaging features known to be associated with ...
journal_title：European radiology
pub_type： 临床试验,杂志文章
doi：10.1007/s00330-009-1706-x
更新日期：2010-07-01 00:00:00
