Abstract:
:To assess both sensitivity and specificity of digital chest radiography alone and in conjunction with dual-exposure dual-energy chest radiography for the detection and classification of pulmonary nodules. One hundred patients with a total of 149 lung nodules (3-45 mm; median, 11 mm) confirmed by CT were included in this study. Dual-exposure dual-energy chest radiographies of each patient were obtained using a CsI detector system. Experienced board-certified chest radiologists from four different medical centers in Europe reviewed standard chest radiographs alone and in conjunction with dual-energy images blinded and in random order. The reviewers rated the probability of presence, calcification and malignancy of all lung nodules on a five-point rating scale. Lesions detected were identified by applying a specific coordinate system to enable precise verification by the study leader. A receiver-operating characteristic (ROC) analysis was performed. In addition to the 149 true-positive CT proven lesions, 236 false-positive lung nodules were described in digital chest radiographies in conjunction with dual-energy chest radiographies. The cumulative sensitivity of chest radiography in conjunction with dual energy was 43%, specificity was 55%. For digital radiography alone, sensitivity was 35% and specifity was 83%. For the dual energy system, positive predictive value was 58%, and negative predictive value was 66% compared to the digital radiography with a positive predictive value of 59% and a negative predictive value of 65%. Areas under the curve in a ROC analysis resulted in 0.631 (95% confidence interval =0.61 to 0.65) for radiography with dual energy and 0.602 (95% confidence interval =0.58 to 0.63) for digital radiography alone. This difference was not statistically significant. For the detection of lesion calcification or the determination of malignancy, ROC analysis also failed to show significant differences. CsI-based flat-panel dual-exposure dual-energy imaging added to standard chest radiography did not show statistically significant improvement for the detection of pulmonary nodules, nor the identification of calcifications, nor the determination of malignancy.
journal_name
Eur Radioljournal_title
European radiologyauthors
Rühl R,Wozniak MM,Werk M,Laurent F,Mager G,Montaudon M,Pattermann A,Scherrer A,Tasu JP,Pech M,Ricke Jdoi
10.1007/s00330-008-0945-6subject
Has Abstractpub_date
2008-09-01 00:00:00pages
1831-9issue
9eissn
0938-7994issn
1432-1084journal_volume
18pub_type
临床试验,杂志文章,多中心研究abstract:OBJECTIVES:To review the role of imaging in the diagnosis of recurrent disease in previously treated non-small cell lung cancer (NSCLC) and discuss the imaging pitfalls. METHODS:A comprehensive review of published literature on CT and PET imaging of NSCLC recurrence was performed. Diagnostic and prognostic values are ...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-011-2299-8
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVES:Osteoporotic vertebral fractures are responsible for acute pain and disability that may persist for more than 2 months. We wanted to identify predicting factors for mid-term outcome after vertebroplasty. METHODS:We included consecutive patients who underwent vertebroplasty for fragility fractures with persi...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-017-5274-1
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVES:In chemotherapy monitoring, an estimation of the change in tumour size is an important criterion for the assessment of treatment success. This requires a comparison between corresponding lesions in the baseline and follow-up computed tomography (CT) examinations. We evaluate the clinical benefits of an autom...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-012-2545-8
更新日期:2012-12-01 00:00:00
abstract::Our objective was to study Gd-EOB-DTPA for the characterization of focal liver lesions by means of dynamic MR imaging. A double-blind and randomized dose-ranging phase-2 clinical trial was performed in 31 patients (liver metastases n = 23, hepatocellular carcinoma n = 4, and hemangioma n = 4) at a field strength of 1....
journal_title:European radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s003300050150
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVES:To assess the accuracy and efficiency of a threshold-based, semi-automated cardiac MRI segmentation algorithm in comparison with conventional contour-based segmentation and aortic flow measurements. METHODS:Short-axis cine images of 148 patients (55 ± 18 years, 81 men) were used to evaluate left ventricular...
journal_title:European radiology
pub_type: 杂志文章
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更新日期:2016-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00330-006-0562-1
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVE:To investigate comparative effectiveness of drug-eluting bead transarterial chemoembolization (DEB-TACE) versus Yttrium-90 (90Y)-radioembolization for hepatocellular carcinoma (HCC). METHODS:Studies comparing conventional (c)TACE versus 90Y-radioembolization or DEB-TACE for HCC treatment were identified usin...
journal_title:European radiology
pub_type: 杂志文章,meta分析
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更新日期:2017-05-01 00:00:00
abstract::Axillary management in patients with breast cancer has become much less invasive with the introduction of sentinel lymph node biopsy (SLNB). However, over 70 % of SLNBs are negative, questioning the generic use of this invasive procedure. Emerging evidence indicates that breast cancer patients with a low axillary burd...
journal_title:European radiology
pub_type: 杂志文章,评审
doi:10.1007/s00330-013-3009-5
更新日期:2014-02-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-002-1584-y
更新日期:2002-12-01 00:00:00
abstract::Vertebral fractures are the hallmark of osteoporosis and are associated with increased morbility and mortality. Because a majority of vertebral fractures often occur in absence of specific trauma and are asymptomatic, their identification is radiographic. The two most widely used methods to determine the severity of v...
journal_title:European radiology
pub_type: 杂志文章,评审
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更新日期:2008-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2016-08-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003309900272
更新日期:2000-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2005-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3353-0
更新日期:2014-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s003300000755
更新日期:2001-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2018-08-01 00:00:00
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更新日期:2017-10-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章,随机对照试验
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更新日期:2008-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00330-014-3281-z
更新日期:2014-10-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
doi:10.1007/s00330-009-1508-1
更新日期:2009-12-01 00:00:00
abstract::Accessory ossicles and sesamoid bones are frequent findings in routine radiographs of the ankle and foot. They are commonly considered fortuitous and unrelated to the patient's complaint; however, they may eventually cause painful syndromes or degenerative changes in response to overuse and trauma. They may also suffe...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-003-2011-8
更新日期:2003-12-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-014-3544-8
更新日期:2015-06-01 00:00:00
abstract::Lesion area measurement in multiple sclerosis (MS) is one of the key points in evaluating the natural history and in monitoring the efficacy of treatments. This study was performed to check the intra- and inter-observer agreement variability of a locally developed Growing Region Segmentation Software (GRES), comparing...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300100978
更新日期:2002-04-01 00:00:00
abstract:OBJECTIVES:To evaluate a deep convolutional neural network (dCNN) for detection, highlighting, and classification of ultrasound (US) breast lesions mimicking human decision-making according to the Breast Imaging Reporting and Data System (BI-RADS). METHODS AND MATERIALS:One thousand nineteen breast ultrasound images f...
journal_title:European radiology
pub_type: 杂志文章
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更新日期:2019-10-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
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更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:To determine the value of perfusion computed tomography (CT-p) in the quantitative assessment of tumour-related neoangiogenesis processes in patients with hepatocellular carcinoma (HCC). MATERIALS AND METHODS:Fifty-two biopsy proven HCC lesions were examined with dynamic CT investigations during injection of...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-011-2307-z
更新日期:2012-04-01 00:00:00
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journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-010-1745-3
更新日期:2010-08-01 00:00:00