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Integrated imaging of non-small cell lung cancer recurrence: CT and PET-CT findings, possible pitfalls and risk of recurrence criteria.

Abstract：

OBJECTIVES:To review the role of imaging in the diagnosis of recurrent disease in previously treated non-small cell lung cancer (NSCLC) and discuss the imaging pitfalls. METHODS:A comprehensive review of published literature on CT and PET imaging of NSCLC recurrence was performed. Diagnostic and prognostic values are discussed. Representative imaging examples are illustrated. RESULTS:Up to 30% of NSCLC recurrences present as loco-regional, involving treated hemithorax and ipsilateral lymph nodes, while 70% present as metachronous distant metastases. CT and PET-CT play an important role in the early detection of recurrence; indications for imaging vary depending on pathological features. CONCLUSION:Imaging plays a central role in the identification of recurrence and may predict prognosis. KEY POINTS:Lung cancer recurs after surgery in 30% to 75% of patients. CT and PET-CT are crucial in identification of loco-regional recurrence. Knowledge of potential pitfalls is essential, especially for parenchymal or nodal recurrence. CT can diagnose metastases but further examinations (PET-CT, MRI) are often needed. Morphological and functional imaging criteria may help in predicting recurrence.

journal_name

Eur Radiol

journal_title

European radiology

authors

Caulo A,Mirsadraee S,Maggi F,Leccisotti L,van Beek EJ,Bonomo L

doi

10.1007/s00330-011-2299-8

subject

Has Abstract

pub_date

2012-03-01 00:00:00

pages

588-606

issue

3

eissn

0938-7994

issn

1432-1084

journal_volume

22

pub_type

杂志文章,评审

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