Effectiveness of a three-dimensional dual gradient echo two-point Dixon technique for the characterization of adrenal lesions at 3 Tesla.

Abstract:

OBJECTIVE:To compare the sensitivity, specificity, and diagnostic accuracy of fat-only datasets reconstructed using a two-point Dixon technique, with corresponding opposed-phase (OP) and in-phase (IP) datasets for characterization of adrenal lesions at 3 Tesla (T). METHODS:Fifty-nine patients (21 male, 38 female) with 66 adrenal lesions (49 adenomas, 17 nonadenomas) underwent 3D dual gradient-echo 3-T adrenal MR imaging with reconstruction of OP/IP and fat/water datasets. Sensitivity, specificity, and diagnostic accuracy were compared between OP/IP datasets, using the signal intensity index (SII), and fat/water datasets, using the fat fraction and fat ratio. Four radiologists qualitatively assessed OP/IP and fat-only datasets for reader confidence in lesion characterization and image quality. RESULTS:There were significant differences between adenomas and nonadenomas with regard to mean SII, fat fraction, and fat ratio (P < 0.001). There was no significant difference in mean diagnostic accuracy among different evaluation methods using OP/IP and fat/water datasets. Mean readers' scores for lesion characterization were significantly higher for adenomas than for nonadenomas using OP/IP and fat-only datasets. There was no significant difference between the two datasets regarding mean readers' scores for image quality. CONCLUSION:Fat-only images can readily differentiate adrenal adenomas from nonadenomas, with diagnostic accuracy comparable to OP/IP images.

journal_name

Eur Radiol

journal_title

European radiology

authors

Marin D,Dale BM,Bashir MR,Ziemlewicz TJ,Ringe KI,Boll DT,Merkle EM

doi

10.1007/s00330-011-2244-x

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

259-68

issue

1

eissn

0938-7994

issn

1432-1084

journal_volume

22

pub_type

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