Mutualism and pathogenesis in Xenorhabdus and Photorhabdus: two roads to the same destination.

abstract：:The TonB system of Escherichia coli (TonB/ExbB/ExbD) transduces the protonmotive force (pmf) of the cytoplasmic membrane to drive active transport by high-affinity outer membrane transporters. In this study, chromosomally encoded ExbD formed formaldehyde-linked complexes with TonB, ExbB and itself (homodimers) in vivo...

journal_title：Molecular microbiology

authors： Ollis AA,Manning M,Held KG,Postle K

更新日期：2009-08-01 00:00:00

abstract：:In this work, we have studied the in vitro translational features of a bicistronic mRNA of the extremely thermophilic Archaeon Sulfolobus solfataricus, with the aim of determining the nature of the cis-acting signals controlling the recognition of the translation initiation sites in the Archaea. We found that the most...

journal_title：Molecular microbiology

authors： Condò I,Ciammaruconi A,Benelli D,Ruggero D,Londei P

更新日期：1999-10-01 00:00:00

abstract：:Fungi appear to be unique in their requirement for a third soluble translation elongation factor. This factor, designated elongation factor 3 (EF-3), was first described in the yeast Saccharomyces cerevisiae and has subsequently been identified in a wide range of fungal species including Candida albicans and Schizosac...

journal_title：Molecular microbiology

authors： Belfield GP,Tuite MF

更新日期：1993-08-01 00:00:00

abstract：:Entry of Listeria monocytogenes into cultured epithelial cells requires production of internalin, a protein with features characteristic of some Gram-positive bacterial surface proteins, in particular an LPXTG motif preceding a hydrophobic sequence and a few basic residues at its C-terminal end. By immunofluorescence ...

journal_title：Molecular microbiology

authors： Lebrun M,Mengaud J,Ohayon H,Nato F,Cossart P

更新日期：1996-08-01 00:00:00

abstract：:The translocation of the diphtheria toxin catalytic domain from the lumen of early endosomes into the cytosol of eukaryotic cells is an essential step in the intoxication process. We have previously shown that the in vitro translocation of the catalytic domain from the lumen of toxin pre-loaded endosomal vesicles to t...

journal_title：Molecular microbiology

authors： Trujillo C,Taylor-Parker J,Harrison R,Murphy JR

更新日期：2010-05-01 00:00:00

abstract：:The cyanobacterium Synechocystis sp. PCC 6803 expresses four different FtsH protease subunits (FtsH1-4) that assemble into specific homo- and heterocomplexes. The FtsH2/FtsH3 complex is involved in photoprotection but the physiological roles of the other complexes, notably the essential FtsH1/FtsH3 complex, remain unc...

journal_title：Molecular microbiology

authors： Krynická V,Tichý M,Krafl J,Yu J,Kaňa R,Boehm M,Nixon PJ,Komenda J

更新日期：2014-11-01 00:00:00

abstract：:The Rhizobium leguminosarum biovar phaseoli symbiotic plasmid pRP2JI carries a gene, melA, specifying the enzyme tyrosinase, which is responsible for the production of the pigment melanin in these bacteria. Transcription of melA is activated by the nifA gene of Rhizobium and, when the cloned melA gene is transferred t...

journal_title：Molecular microbiology

authors： Hawkins FK,Johnston AW

更新日期：1988-05-01 00:00:00

abstract：:Phospholipid homeostasis of the bacterial membrane is maintained by biochemical regulation of the synthesis enzymes depending on the environment. However, genes encoding phospholipid synthesis enzymes might also be regulated during stress responses, in order for the bacteria to adapt their growth to changing environme...

journal_title：Molecular microbiology

authors： Wahl A,My L,Dumoulin R,Sturgis JN,Bouveret E

更新日期：2011-06-01 00:00:00

abstract：:The suf and isc operons of Escherichia coli have been implicated in Fe-S cluster assembly. However, it has been unclear why E. coli has two systems for Fe-S cluster biosynthesis. We have examined the regulatory characteristics and mutant phenotypes of both operons to discern if the two operons have redundant functions...

journal_title：Molecular microbiology

authors： Outten FW,Djaman O,Storz G

更新日期：2004-05-01 00:00:00

abstract：:Lipochitin Nod signals are produced by rhizobia and are required for the establishment of a nitrogen-fixing symbiosis with a legume host. The nodulation genes encode products required for the synthesis of this signal and are induced in response to plant-produced flavonoid compounds. The addition of chitin and lipo-chi...

journal_title：Molecular microbiology

authors： Loh JT,Stacey G

更新日期：2001-09-01 00:00:00

abstract：:In contrast to most primary metabolism genes, the genes involved in secondary metabolism and certain nutrient utilization pathways are clustered in fungi. Recently a nuclear protein, LaeA, was found to be required for the transcription of several secondary metabolite gene clusters in Aspergillus nidulans. Here we show...

journal_title：Molecular microbiology

authors： Bok JW,Noordermeer D,Kale SP,Keller NP

更新日期：2006-09-01 00:00:00

abstract：:We have cloned a gene encoding a polygalacturonase (PG) in the filamentous fungus Aspergillus niger RH5344. The structural gene comprises 1141 bp coding for 362 amino acids and the open reading frame is disrupted by one intron of 52 bp. Eukaryotic consensus sequences for transcription regulation are found only in devi...

journal_title：Molecular microbiology

authors： Ruttkowski E,Khanh NQ,Wientjes FJ,Gottschalk M

更新日期：1991-06-01 00:00:00

abstract：:Bacteria differ from eukaryotes by having the enzyme DNA gyrase, which catalyses the ATP-dependent negative supercoiling of DNA. Negative supercoils are essential for condensing chromosomes into an interwound (plectonemic) and branched structure known as the nucleoid. Topo-1 removes excess supercoiling in an ATP-indep...

journal_title：Molecular microbiology

authors： Booker BM,Deng S,Higgins NP

更新日期：2010-12-01 00:00:00

abstract：:Cyclic di-GMP (c-di-GMP) controls the transition between sessility and motility in many bacterial species. This regulation is achieved by a variety of mechanisms including alteration of transcription initiation and inhibition of flagellar function. How c-di-GMP inhibits the motility of Vibrio cholerae has not been det...

journal_title：Molecular microbiology

authors： Srivastava D,Hsieh ML,Khataokar A,Neiditch MB,Waters CM

更新日期：2013-12-01 00:00:00

abstract：:Campylobacter jejuni, a prevalent cause of bacterial gastroenteritis, must adapt to different environments to be a successful pathogen. We previously identified a C. jejuni two-component regulatory system (Cj1226/7c) as upregulated during cell infections. Analyses described herein led us to designate the system CprRS ...

journal_title：Molecular microbiology

authors： Svensson SL,Davis LM,MacKichan JK,Allan BJ,Pajaniappan M,Thompson SA,Gaynor EC

更新日期：2009-01-01 00:00:00

abstract：:In the yeast Saccharomyces cerevisiae, PKA and Sch9 exert similar physiological roles in response to nutrient availability. However, their functional redundancy complicates to distinguish properly the target genes for both kinases. In this article, we analysed different phenotypic read-outs. The data unequivocally sho...

journal_title：Molecular microbiology

authors： Roosen J,Engelen K,Marchal K,Mathys J,Griffioen G,Cameroni E,Thevelein JM,De Virgilio C,De Moor B,Winderickx J

更新日期：2005-02-01 00:00:00

abstract：:Bacillus subtilis forms long chains of cells during growth and biofilm formation. Cell separation is mediated by autolysins, whose genes are under the negative control of a heteromeric complex composed of the proteins SinR and SlrR. Formation of the SinR-SlrR complex is governed by a self-reinforcing, double-negative ...

journal_title：Molecular microbiology

authors： Chai Y,Kolter R,Losick R

更新日期：2010-10-01 00:00:00

abstract：:In cyanobacteria and chloroplasts, exposure to HL damages the photosynthetic apparatus, especially the D1 subunit of Photosystem II. To avoid chronic photoinhibition, a PSII repair cycle operates to replace damaged PSII subunits with newly synthesised versions. To determine the sub-cellular location of this process, w...

journal_title：Molecular microbiology

authors： Sacharz J,Bryan SJ,Yu J,Burroughs NJ,Spence EM,Nixon PJ,Mullineaux CW

更新日期：2015-05-01 00:00:00

abstract：:Photoregulation of pigmentation during complementary chromatic acclimation (CCA) is well studied in Fremyella diplosiphon; however, mechanistic insights into the CCA-associated morphological changes are still emerging. F. diplosiphon cells are rectangular under green light (GL), whereas cells are smaller and spherical...

journal_title：Molecular microbiology

authors： Singh SP,Montgomery BL

更新日期：2014-07-01 00:00:00

abstract：:The increase in bacterial resistance to multiple drugs represents a serious and growing health risk. One component of multidrug resistance (MDR) is a group of multidrug transporters that are often regulated at the transcriptional level by repressors and/or activators. Some of these transcription factors are also multi...

journal_title：Molecular microbiology

authors： Schumacher MA,Brennan RG

更新日期：2002-08-01 00:00:00

abstract：:A Rhizobium phaseoli cytochrome mutant, unable to oxidize N,N,N',N'-tetramethyl-p-phenylenediamine (TMPD), was isolated after Mu-dl (Kan lac) mutagenesis of the wild-type strain CE-3. Mutant strain CFN4202 had sixfold less haem-c but similar levels of b type, o and aa3 cytochromes than the wild-type strain. CFN4202 st...

journal_title：Molecular microbiology

authors： Soberón M,Aguilar GR,Sánchez F

更新日期：1993-04-01 00:00:00

abstract：:Crown gall tumorigenesis by Agrobacterium tumefaciens requires the co-ordinate transcriptional induction of a set of pathogenesis genes. At least three classes of environmental stimuli act synergistically to induce these genes: (i) monocyclic aromatic hydrocarbons such as acetosyringone, coniferyl alcohol, and vanilli...

journal_title：Molecular microbiology

authors： Winans SC

更新日期：1991-10-01 00:00:00

abstract：:This study examined the role of P fimbriae in the establishment of bacteriuria. Patients (n = 17) were subjected to intravesical inoculation with an asymptomatic bacteriuria strain, Escherichia coli 83972, or its P-fimbriated (pap+/prs+) transformants. As shown by groupwise analysis, the pap+/prs+ transformants establ...

journal_title：Molecular microbiology

authors： Wullt B,Bergsten G,Connell H,Röllano P,Gebretsadik N,Hull R,Svanborg C

更新日期：2000-11-01 00:00:00

abstract：:Bacteria in terrestrial habitats frequently reside as biofilm communities on surfaces that are unsaturated, i.e. biofilms are covered in water films varying in thickness depending on the environmental conditions. Water availability in these habitats is influenced by the osmolarity of the water (solute stress) and by c...

journal_title：Molecular microbiology

authors： van de Mortel M,Halverson LJ

更新日期：2004-05-01 00:00:00

abstract：:A 2.7 kb fragment of Helicobacter pylori UA802 chromosomal DNA was cloned and sequenced. Three open reading frames (designated ORF1, ORF2 and ORF3, respectively) were predicted from the DNA sequence, of which ORF1 and ORF2 appeared to be located within the same operon. The deduced 611-amino-acid sequence of ORF1, a P-...

journal_title：Molecular microbiology

authors： Ge Z,Hiratsuka K,Taylor DE

更新日期：1995-01-01 00:00:00

abstract：:Type III secretion systems (T3SSs) are protein injection devices essential for the interaction of many Gram-negative bacteria with eukaryotic cells. While Shigella assembles its T3SS when the environmental conditions are appropriate for invasion, secretion is only activated after physical contact with a host cell. Fir...

journal_title：Molecular microbiology

authors： Roehrich AD,Guillossou E,Blocker AJ,Martinez-Argudo I

更新日期：2013-02-01 00:00:00

abstract：:The six biochemical steps of the de novo pyrimidine biosynthesis pathway are conserved in all known organisms. However, in animals and fungi, unlike prokaryotes, at least the first two activities are grouped on a multifunctional enzyme. Here, we report cloning, mapping and transcriptional characterization of some pyri...

journal_title：Molecular microbiology

authors： Aleksenko A,Liu W,Gojkovic Z,Nielsen J,Piskur J

更新日期：1999-08-01 00:00:00

abstract：:In enteric bacteria, proteins of the Hha/YmoA family play a role in the regulation of gene expression in response to environmental factors. Interaction of both Hha and YmoA with H-NS has been reported, and an Hha/H-NS complex has been shown to modulate expression in Escherichia coli of the haemolysin operon of plasmid...

journal_title：Molecular microbiology

authors： Paytubi S,Madrid C,Forns N,Nieto JM,Balsalobre C,Uhlin BE,Juárez A

更新日期：2004-10-01 00:00:00

abstract：:Because the ferric uptake regulator (fur) appears to be an essential gene in Pseudomonas aeruginosa, resistance to manganese was used as an enrichment to isolate strains carrying point mutations in the fur gene in order to assess its role in the co-ordinate expression of siderophores and exotoxin A (ETA). This report ...

journal_title：Molecular microbiology

authors： Barton HA,Johnson Z,Cox CD,Vasil AI,Vasil ML

更新日期：1996-09-01 00:00:00

abstract：:During pathogenesis, Mycobacterium tuberculosis (Mtb) colonizes environments, such as the macrophage or necrotic granuloma, that are acidic and rich in cholesterol and fatty acids. The goal of this study was to examine how acidic pH and available carbon sources interact to regulate Mtb physiology. Here we report that ...

journal_title：Molecular microbiology

authors： Baker JJ,Johnson BK,Abramovitch RB

更新日期：2014-10-01 00:00:00