Amiodarone-induced torsades de pointes: the possible facilitatory role of digoxin.

Abstract:

:Poorly controlled supraventricular arrhythmias in a hypokalaemic 74 year old woman were treated with oral amiodarone. This caused torsades de pointes, and was preceded by marked prolongation of the QT interval. The induction of torsades de pointes by amiodarone is thought to be an idiosyncratic reaction to amiodarone itself which is facilitated by electrolytic abnormalities. The present case, however, indicates the possibility of a pro-arrhythmic effect secondary to an interaction between amiodarone and digoxin.

journal_name

Int J Cardiol

authors

Bajaj BP,Baig MW,Perrins EJ

doi

10.1016/0167-5273(91)90369-z

subject

Has Abstract

pub_date

1991-11-01 00:00:00

pages

335-7

issue

2

eissn

0167-5273

issn

1874-1754

pii

0167-5273(91)90369-Z

journal_volume

33

pub_type

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