Abstract:
:Patients with coronary artery disease (CAD) can present with spontaneous ventricular arrhythmias occurring outside the context of an acute coronary syndrome with no apparent identifiable reversible cause. In addition to secondary prevention medications, implantable cardiac defibrillator (ICD) remains the main therapeutic intervention to reduce the risk of subsequent mortality and morbidity. Investigations prior to ICD implantation may identify the presence of angiographically significant epicardial coronary stenoses in previously asymptomatic patients, alongside other arrhythmic substrates such as myocardial scar and impaired left ventricular systolic function. So does coronary revascularisation in these patients reduce the occurrence of appropriate ICD shocks in the long run? In this article we comprehensively review the literature to answer the primary question of whether coronary revascularisation reduces recurrent ventricular arrhythmia burden among patients with CAD receiving an ICD, with focus on those presenting with ventricular arrhythmias outside the context of acute coronary syndrome. With growing evidence of the adverse prognostic impact of appropriate ICD discharges and an ever-increasing number of ICD implants world-wide, we believe that this question is of paramount importance. We summarise the available evidence to draw conclusions about the appropriate management strategy and also highlight areas of uncertainty that require attention in future research.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Viswanathan K,Qureshi AC,Tayebjee MHdoi
10.1016/j.ijcard.2012.04.100subject
Has Abstractpub_date
2013-06-20 00:00:00pages
304-9issue
2eissn
0167-5273issn
1874-1754pii
S0167-5273(12)00521-9journal_volume
166pub_type
杂志文章,评审abstract::Today, drug-eluting metal stents are considered the gold standard for interventional treatment of coronary artery disease. While providing inhibition of neointimal hyperplasia, drug-eluting metal stents have many limitations such as the risk of late and very late stent thrombosis, restriction of vascular vasomotion an...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2016.04.027
更新日期:2016-07-15 00:00:00
abstract::To assess whether derivation of an effective mitral prosthetic valve area using the continuity equation provides an improved functional assessment of the Bjork-Shiley mitral prosthesis over the pressure half-time method, Doppler echocardiographic studies were performed in 43 patients 12 +/- 7 months following the valv...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(94)90214-3
更新日期:1994-03-01 00:00:00
abstract::Pulmonary arterial hypertension (PAH) associated with congenital heart disease (CHD) due to systemic to pulmonary shunting is associated with a high risk of morbidity and mortality. In this study we evaluated 4 years treatment effect of bosentan on exercise capacity and quality of life and survival rates in 64 adult p...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2011.06.064
更新日期:2013-03-20 00:00:00
abstract::We studied haemodynamic changes during dobutamine stress echocardiography in 69 patients (mean age 58 years, 6 female, 63 male) referred for investigation of chest pain. We used a standard protocol of 3 min stages using infusion rates of 5, 10, 20, 30 and 40 micrograms/kg/min. Heart rate rose from 74 (13) to 123 (21) ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(96)02846-x
更新日期:1997-01-03 00:00:00
abstract::Myocardial bridging is present when a segment of a major epicardial coronary artery, the 'tunnelled artery', runs intramurally through the myocardium. With each systole, the coronary artery is compressed. The pathophysiology of myocardial bridging is incompletely understood. With each systole, the coronary artery is c...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2009.03.106
更新日期:2012-01-26 00:00:00
abstract:OBJECTIVE:Because the lipoprotein effects of statin and fibric acid derivatives therapies differ, we studied the effects of these therapies in patients with hyperlipidemia on lipoproteins, vasomotor function, and plaque stability. METHODS:We administered simvastatin, 20 mg daily, to 27 patients with hypercholesterolem...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ijcard.2003.09.007
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:To study the joint prevalence of elevated blood pressure and raised total cholesterol in adult individuals and to estimate the multifactorial cardiovascular risk associated with this clustering. MATERIAL AND METHODS:Data were obtained through pooling of databases from large cross-sectional representative pop...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2005.08.037
更新日期:2006-06-16 00:00:00
abstract:BACKGROUND:FFR-guided coronary intervention is recommended for patients with intermediate stenoses. However, concerns exist with this approach in anatomically prognostic disease. METHODS:In this prospective, multicentre study, we consecutively enrolled patients found to have FFR negative lesions in anatomically signif...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2018.06.013
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:Few data are available about safety of second generation drug eluting stents in an all-comer ST elevation myocardial infarction (STEMI) population. We sought to investigate the predictors and clinical implications of 1-year stent thrombosis (ST) in patients with STEMI, included in the EXAMINATION trial. MET...
journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2013.03.036
更新日期:2013-10-03 00:00:00
abstract::We studied hypertrophic patterns in the electrocardiograms of 60 Nigerian hypertensives. Thirty were in heart failure and 30 without failure (matched for age and sex). Combined left ventricular and left atrial hypertrophy was the commonest finding occurring in 58.3%, followed by left ventricular hypertrophy alone in 3...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(91)90129-d
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to assess stressechocardiography (SE) for risk stratification of asymptomatic type 2 diabetic patients (DM2) without known coronary artery disease CAD. METHODS:A total of 211 consecutive, asymptomatic DM2 patients underwent exercise (n=177) or dobutamine (n=34) SE and were foll...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2007.07.085
更新日期:2009-01-09 00:00:00
abstract:BACKGROUND:Activated monocytes/macrophages, neutrophils, endothelial cells and smooth muscle cells participate in the restenosis processes. Monocytes/macrophages and neutrophils are activated by lipopolysaccharide (LPS) via CD14. Endothelial cells and smooth muscle cells are also stimulated by soluble CD14 (sCD14)-LPS ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2003.05.007
更新日期:2004-03-01 00:00:00
abstract::Cardiac catheterisation using the Sones technique was planned as a day case procedure in 855 of 1662 consecutive patients admitted for cardiac catheterisation. Of these, 810 (95%) were discharged the same day. Forty-five (5%) needed overnight hospitalization, 34 for reasons connected with the procedure and 11 for othe...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(89)90034-x
更新日期:1989-07-01 00:00:00
abstract::In this article the authors deal with the intricate relationship between acute brain injuries and stress cardiomyopathies. The complexity of heart–brain relationship raises some questions about the occurrence of Takotsubo cardiomyopathy in young patients with acute brain ischemia and vice versa. ...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2009.05.003
更新日期:2010-11-19 00:00:00
abstract:BACKGROUND:Ghrelin, was observed to have treatment-potential for severe chronic heart failure (CHF) and cardiac cachexia based on anti-cachectic and cardio-protective effects. METHODS:We performed two studies to assess the effects of human ghrelin on food intake, body weight and body composition, as well as heart func...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2008.06.094
更新日期:2009-11-12 00:00:00
abstract:BACKGROUND:In Marfan syndrome, the mitral valve prolapse, ranging from nonclassic to classic form on the basis of the leaflet thickness, is a common condition characterized by a highly variable structural abnormality. We investigated the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) I/D and a...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2006.12.015
更新日期:2008-01-24 00:00:00
abstract:BACKGROUND:Cardiovascular diseases represent the leading cause of death in Italy and one of the most frequent cause of disability in the elderly. The aim of the study was to investigate the influence of age and sex of patient on the utilisation of cardiac procedure and interventions in Italy. METHODS:Retrospective ana...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2004.03.032
更新日期:2005-05-25 00:00:00
abstract:BACKGROUND:Patients with Fabry disease (FD) develop progressive left ventricular hypertrophy (LVH). In screening studies in patients with LVH, the prevalence of FD ranges from 0 to 12%. This variability is attributable to different factors like diverging inclusion and exclusion criteria, the evaluation of selected popu...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.ijcard.2012.06.069
更新日期:2013-09-10 00:00:00
abstract::In this study, the effect of celiprolol (beta-1-antagonist with beta-2-agonistic activity) on hemodynamic and electrocardiographic parameters of patients with congestive heart failure due to ischemic (iCMP) and non-ischemic (niCMP) origin should be evaluated. Sixteen patients were included into the study, nine with iC...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章
doi:10.1016/s0167-5273(98)00377-5
更新日期:1999-03-15 00:00:00
abstract:BACKGROUND:Empagliflozin is reported to reduce cardiovascular mortality and the rate of hospitalization for heart failure in type 2 diabetic patients with prior cardiovascular events. The mechanisms underlying the cardiac effects of this sodium/glucose transporter 2 (SGT2) inhibitor have not yet been clarified, though ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2017.05.032
更新日期:2017-09-15 00:00:00
abstract::Takayasu's disease is an unusual arteritis that affects young females. Stroke is a common presenting symptom usually due to sudden occlusion of one or more thoracic aortic arch arteries. The author recommends prophylactic bypass of involved aortic arch arteries to prevent strokes. Abdominal aortic involvement causes s...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(00)00179-0
更新日期:2000-08-31 00:00:00
abstract:AIM:To assess clinical characteristics, use of resources and costs of patients at very high risk (VHR) of cardiovascular (CV) events. Further, to assess how VHR patients are treated with statins (rate of prescription, dosages, adherence). METHODS AND RESULTS:A record linkage analysis was carried out of patient demogra...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2017.02.108
更新日期:2017-11-01 00:00:00
abstract::We report a case of spontaneous resolution of neoaneurysm of the coronary artery complicating paclitaxel-eluting TAXUS stent implantation in the proximal left anterior descending artery in a 56-year-old female. ...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2006.01.056
更新日期:2006-09-20 00:00:00
abstract::The present study has examined the role of diltiazem as a protective agent in a canine model of norepinephrine cardiotoxicity. Effects of diltiazem, 20 micrograms/kg/min x 5 min pretreatment followed by 10 micrograms/kg/min x 90 min, or saline infusion were examined at baseline and 1 h after infusion of norepinephrine...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(92)90105-c
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:Patients who have had a prior myocardial infarction (MI) are at increased risk for adverse outcomes after subsequent percutaneous coronary intervention (PCI). OBJECTIVE:The objective of this study is to examine the efficacy and safety of cangrelor, a potent intravenous P2Y12 inhibitor, in patients with prio...
journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2017.10.006
更新日期:2018-01-01 00:00:00
abstract::We studied the prognostic relevance of inducible ventricular tachycardia in 32 patients with dilated cardiomyopathy and spontaneous nonsustained asymptomatic ventricular tachycardia. Programmed ventricular stimulation included basic drive cycle lengths of 600, 500, 430, 370, 330 and 300 msec at single, double, and tri...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(90)90224-s
更新日期:1990-11-01 00:00:00
abstract:OBJECTIVE:The use of implantable cardiac monitors (ICM) is highly useful in syncope workup. Latest-generation devices can detect asymptomatic episodes of atrial fibrillation. The main objective of this study was to determine the incidence of subclinical atrial fibrillation (AF) detected in a patient population undergoi...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2020.05.078
更新日期:2020-10-01 00:00:00
abstract::After a documented decline in the incidence of acute rheumatic fever in the United States during the past three decades, an apparent resurgence has occurred in the mid-1980s. Although standards of living have continued to improve with concomitant decrease in crowding and easier accessibility to medical care, the preci...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/0167-5273(88)90003-4
更新日期:1988-10-01 00:00:00
abstract::Matrix metalloproteinases are involved in the development of acute coronary syndromes, but they are not reliable clinical markers of the occurrence or the outcome of this syndrome. Many limitations in their assessment account for such failure. Functional genetic polymorphisms, as alternatives to plasma levels, might b...
journal_title:International journal of cardiology
pub_type: 评论,信件
doi:10.1016/j.ijcard.2008.04.005
更新日期:2009-05-29 00:00:00
abstract:BACKGROUND/OBJECTIVES:In the last two decades, in Brazil, there has been a decreasing trend of consumption of in natura or minimally processed food, while intake of ultra-processed food has markedly increased. We estimated the contribution of dietary intake in trends from coronary heart disease mortality (CHDM), cardio...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.04.176
更新日期:2016-08-15 00:00:00