Abstract:
AIM:To assess clinical characteristics, use of resources and costs of patients at very high risk (VHR) of cardiovascular (CV) events. Further, to assess how VHR patients are treated with statins (rate of prescription, dosages, adherence). METHODS AND RESULTS:A record linkage analysis was carried out of patient demographics, drug prescriptions, hospital discharge, specialty procedures from the ARNO Observatory, including 2,989,512 subjects of Local Health Units well representing the whole Italian country. Accrual lasted from January 1 to December 31, 2011. Among these subjects, 17,126 (0.56%) experienced a CV event, representing the cohort at VHR. Between VHR patients, 4810 (28.1%) individuals represent the diabetic cohort. Mean age of VHR patients was 77±13, females were 43.8%. Statins and/or ezetimibe were prescribed in 59.9% and 68.5% during the first year of follow respectively in VHR and VHR-diabetics. Prescription continuity at 1year was 64.7% in patients at VHR, and 63.4% in VHR diabetics. At 1year, at least one re-hospitalization occurred in 55.0% of patients for a total of 17,631 re-hospitalizations. In VHR diabetics, at least one readmission occurred in 59.6% of patients. Average annual cost for a single VHR patient was €11,644 (drugs: €1007; hospitalizations: €10,097; specialty procedures: €540); the corresponding cost for diabetics was €13,199 (drugs: €1394; hospitalizations: €11,032, specialty procedures €773). CONCLUSIONS:Atherothrombotic events are a relevant cause of hospitalization in the community setting. Prescription rate and continuity of treatment with statins seem to be at least suboptimal. NHS costs are high, with re-hospitalizations being the main cost-driver.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Maggioni AP,Calabria S,Rossi E,Martini N,on the behalf of the ARNO Observatory.doi
10.1016/j.ijcard.2017.02.108subject
Has Abstractpub_date
2017-11-01 00:00:00pages
62-67eissn
0167-5273issn
1874-1754pii
S0167-5273(16)33124-2journal_volume
246pub_type
杂志文章,多中心研究abstract:BACKGROUND:Stroke is the second cause of death worldwide and over than 80% of deaths occurs in developing countries. However, its characteristics in the Democratic Republic of Congo (DRC) are poorly defined. This study aimed to describe the key features of stroke in a hospital population of Kinshasa in DRC and to asses...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2017.04.063
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVES:To evaluate the association between body mass index (BMI) z-score and left atrial (LA) size in childhood and to determine whether LA size differs between healthy weight (HW), overweight (OW) and obese (OB) children. BACKGROUND:LA enlargement is an independent risk factor for adverse cardiovascular outcomes....
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2008.11.157
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abstract:BACKGROUND:Information on the association between γ-glutamyltransferase (GGT) and the incidence of atrial fibrillation (AF) is scarce. We evaluated the association between GGT and AF incidence, and the interaction between GGT and obesity on developing AF in a large population-based cohort. METHODS:We evaluated 266,550...
journal_title:International journal of cardiology
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更新日期:2017-10-15 00:00:00
abstract::Peripartum cardiomyopathy (PPCM) is a rare disorder in which left ventricular dysfunction and symptoms of heart failure occur in the peripartum period in previously healthy women. Incidence of PPCM ranges from 1 in 1300 to 1 in 15,000 pregnancies. The etiology of PPCM is unknown, but viral, autoimmune, and idiopathic ...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
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abstract::Tako-Tsubo cardiomyopathy is characterized by a transient and reversible left ventricular dysfunction possibly due to a catecholamine-mediated myocardial stunning. This form of cardiomyopathy is rarely associated with cardiogenic shock. Here we report on a patient with Tako-Tsubo cardiomyopathy induced low output fail...
journal_title:International journal of cardiology
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更新日期:2010-11-19 00:00:00
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doi:10.1016/s0167-5273(02)00014-1
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journal_title:International journal of cardiology
pub_type: 评论,信件
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更新日期:2009-05-29 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2014.02.037
更新日期:2014-04-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,meta分析
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更新日期:2018-08-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2003-06-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2012.05.108
更新日期:2013-09-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
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更新日期:2009-04-17 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
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更新日期:2010-08-20 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2017.05.041
更新日期:2017-09-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2008.10.007
更新日期:2009-02-20 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2016.04.064
更新日期:2016-07-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2007.11.046
更新日期:2009-04-03 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.06.235
更新日期:2016-10-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2005-03-30 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2016-10-15 00:00:00
abstract:AIMS:To recapitulate progressive human dilated cardiomyopathy (DCM) and heart block in the Lmna R225X mutant mice model and investigate the molecular basis of LMNA mutation induced cardiac conduction disorders (CD); To investigate the potential interventional impact of exercise endurance. METHODS AND RESULTS:A Lmna R2...
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2018-01-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2016-11-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2016.04.068
更新日期:2016-07-15 00:00:00
abstract:OBJECTIVES:Aim of this study was to evaluate different response in platelet reactivity and vessel healing using high-resolution frequency-domain optical coherence tomography (FD-OCT) in patients with femoropopliteal artery disease treated with ZILVER PTX drug eluting stents (DES), and randomly assigned to clopidogrel o...
journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2020-04-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 传,历史文章,杂志文章
doi:10.1016/j.ijcard.2012.06.046
更新日期:2013-07-31 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2007-07-31 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
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更新日期:2013-07-15 00:00:00
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pub_type: 杂志文章
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更新日期:2002-12-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2008.12.175
更新日期:2011-01-21 00:00:00