Abstract:
OBJECTIVE:To assess benefit and harms of adding an eHealth intervention to health education and individual counseling in adolescents with congenital heart disease. DESIGN:Randomized clinical trial. SETTING:Denmark. PATIENTS:A total of 158 adolescents aged 13-16years with no physical activity restrictions after repaired complex congenital heart disease. INTERVENTIONS:PReVaiL consisted of individually tailored eHealth encouragement physical activity for 52weeks. All patients received 45min of group-based health education and 15min of individual counseling involving patients' parents. OUTCOMES:The primary outcome was maximal oxygen uptake (VO2 peak) at 52weeks after randomization. The secondary outcome was physical activity. Exploratory outcomes were generic and disease-specific questionnaires. RESULTS:In the intervention group, 58 patients (72%) completed the final test, but of those, only 46 (57%) fulfilled the compliance criteria of using the eHealth application for at least 2 consecutive weeks. In the control group, 61 patients (79%) completed both exercise tests. Adjusted for baseline values, the difference between the intervention group and the control group in mean VO2 peak at 1year was -0.65ml·kg(-1)·min(-1) (95% CI -2.66 to 1.36). Between-group differences at 1year in physical activity, generic health-related quality of life, and disease-specific quality of life were not statistically significant. CONCLUSIONS:Adding a tailored eHealth intervention to health education and individual counseling did not affect outcomes among adolescents with congenital heart disease. Our results do not support the use of this eHealth intervention in adolescents with complex congenital heart disease. TRIAL REGISTRATION:Clinical trials.gov identifier: NCT01189981.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Klausen SH,Andersen LL,Søndergaard L,Jakobsen JC,Zoffmann V,Dideriksen K,Kruse A,Mikkelsen UR,Wetterslev Jdoi
10.1016/j.ijcard.2016.07.092subject
Has Abstractpub_date
2016-10-15 00:00:00pages
1100-6eissn
0167-5273issn
1874-1754pii
S0167-5273(16)31429-2journal_volume
221pub_type
杂志文章,随机对照试验abstract::A newborn male is described who presented with interruption of aortic arch associated with ventricular septal defect and pulmonary valve stenosis. He underwent total corrective surgery and was discharged with good clinical results. The combination of significant right ventricular outflow obstruction and interruption o...
journal_title:International journal of cardiology
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journal_title:International journal of cardiology
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abstract:BACKGROUND:There is a lack of studies reporting the influence of DOX treatment on chronically exercised animals. This study intended to determine the effect of endurance swimming training on cardiac muscle tolerance to in vivo DOX-induced damage, analyzing the levels of oxidative stress markers, the response of antioxi...
journal_title:International journal of cardiology
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pub_type: 杂志文章,多中心研究
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pub_type: 临床试验,杂志文章
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journal_title:International journal of cardiology
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