Abstract:
:Prostacyclin is a powerful inhibitor of platelet aggregation and induces relaxation of vascular smooth muscle. We have studied the coronary effects of high local concentrations of prostacyclin in 17 patients during the early stages of acute myocardial infarction. We infused graded concentrations of intracoronary prostacyclin and compared the effects to those of intracoronary isosorbide dinitrate before and after an intracoronary infusion of streptokinase. Considerable dilation of the infarct-related stenosis may follow local infusions of prostacyclin in some patients. In general, however, dilation of the infarct-related stenosis or coronary recanalization did not result from infusion of prostacyclin.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Hackett D,Davies G,Maseri Adoi
10.1016/0167-5273(90)90247-3subject
Has Abstractpub_date
1990-01-01 00:00:00pages
53-7issue
1eissn
0167-5273issn
1874-1754pii
0167-5273(90)90247-3journal_volume
26pub_type
杂志文章abstract:BACKGROUND:Endothelial progenitor cells (EPCs) circulate in the adult peripheral blood and contribute to neovascularization. EPCs are considered to be included in CD34 positive mononuclear cells (CD34+ MNCs). Kinetics of circulating EPCs in congestive heart failure (CHF) has not been fully investigated. METHODS:We det...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2006.07.191
更新日期:2007-07-31 00:00:00
abstract::There has been some debate on usefulness of the exercise test in risk stratification after myocardial infarction in the thrombolytic era. This was assessed in 295 patients of whom 184 were treated with thrombolysis. Each had an exercise test using a modified Naughton protocol within 14 days of acute myocardial infarct...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(94)90128-7
更新日期:1994-11-01 00:00:00
abstract:BACKGROUND:Empagliflozin is reported to reduce cardiovascular mortality and the rate of hospitalization for heart failure in type 2 diabetic patients with prior cardiovascular events. The mechanisms underlying the cardiac effects of this sodium/glucose transporter 2 (SGT2) inhibitor have not yet been clarified, though ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2017.05.032
更新日期:2017-09-15 00:00:00
abstract::Congestive heart failure due to thyrotoxicosis without preexisting heart disease is rare. Indeed, the very existence of a thyrotoxic heart disease has been much discussed. We describe a 44-year-old woman in whom thyrotoxicosis was found to be the sole cause of congestive heart failure. ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(88)90065-4
更新日期:1988-03-01 00:00:00
abstract:OBJECTIVES:Atrial electrical remodeling is considered to play an important role in the appearance of atrial fibrillation. The effect of atrial natriuretic peptide (ANP) on atrial electrical remodeling was evaluated in a canine atrial stimulation model. METHODS:In 15 beagle dogs, electrodes for pacing and recording wer...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2006.12.005
更新日期:2008-01-11 00:00:00
abstract:BACKGROUND:It is unclear whether ischemic stroke patients with known atrial fibrillation (KAF) had different outcomes than those with atrial fibrillation diagnosed after stroke (AFDAS). We aimed to explore the characteristics and outcomes in ischemic stroke patients with KAF or AFDAS. METHODS:Consecutive patients hosp...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2017.11.047
更新日期:2018-06-15 00:00:00
abstract:OBJECTIVE:Oxidative stress seems to play a role in impairing flow-mediated dilation (FMD) in patients with peripheral artery disease (PAD) but the underlying mechanism is still undefined. We evaluated whether NOX2, the catalytic core of NADPH oxidase, the most important producer of reactive oxidant species (ROS), is im...
journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2012.01.069
更新日期:2013-04-30 00:00:00
abstract::The hearts of human embryos, ranging from 3.6 to 25 mM crown-rump length, have been studied in view of the problem of the possible contribution of the atrioventricular endocardial cushions to septation. Serial sections and graphic reconstructions were used. It is concluded that the cushions do not materially contribut...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(85)90261-x
更新日期:1985-05-01 00:00:00
abstract:UNLABELLED:To determine the clinical value of several parameters derived by application of the proximal isovelocity surface area method in the assessment of mitral regurgitation (MR), 28 consecutive patients with angiographic diagnosis of MR underwent color Doppler echocardiography within 48 h of cardiac catheterizatio...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(98)00355-6
更新日期:1999-02-28 00:00:00
abstract::A 15-month-old boy with atrial fibrillation was found to have gross cardiomegaly on a chest radiography; further evaluation by echocardiography showed a giant right atrial aneurysm which is in the form of a cyst like lesion. The patient underwent successful surgical reduction of the right atrium converting his heart r...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2006.02.038
更新日期:2006-10-10 00:00:00
abstract:BACKGROUND:Chronic cocaine use may lead to premature atherosclerosis, however, the prevalence of and risk factors for coronary artery disease in asymptomatic cocaine users have not been reported. METHODS:Between August 2007 and June 2010, 385 African American chronic cocaine users aged 25 to 54 years were consecutivel...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2011.01.032
更新日期:2012-07-12 00:00:00
abstract::To investigate the morbidity after coronary artery bypass grafting, one hundred and seventy-eight patients were retrospectively studied with a minimum follow-up period of one year. Although there was no difference in the incidence and distribution of pain in hospital, seventy percent of patients who had an internal ma...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(91)90124-8
更新日期:1991-01-01 00:00:00
abstract::Low energy level irradiation (LLLI) has been found to modulate biological processes. The effect of LLLI on the development of acute myocardial infarction (MI) was investigated following chronic ligation of the left anterior descending (LAD) coronary artery in laboratory rats. The hearts of 22 rats were laser irradiate...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(01)00503-4
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:Despite the increasing number of reports on lipomatous hypertrophy of interatrial septum, a standardization of measurement of the dimensions of the interatrial septum (IAS) in the different phases of cardiac cycle has not been reported. Moreover, no data on modification of thickness with age and in specific ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(95)02403-j
更新日期:1995-08-01 00:00:00
abstract::Hormone replacement therapy (HRT) was given for many years in order to relieve menopausal symptoms and was used for as long as symptom control was necessary. The Heart and Estrogen/Progestin Replacement Study (HERS) and Women's Health Initiative (WHI) studies showed that HRT should not be given for primary or secondar...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2005.04.002
更新日期:2006-03-08 00:00:00
abstract::A 33-year-old woman presented with an atypical arrhythmia. The electrophysiologic study revealed dual atrioventricular nodal pathways. The difference in conductivity of these tracts enabled simultaneous atrioventricular conduction with a double ventricular response to a single atrial impulse. This disturbance is uncom...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(90)90036-5
更新日期:1990-02-01 00:00:00
abstract:BACKGROUND:Cardiac damage is a major complication of chronic starvation. The aim of this study was to evaluate the changes of left ventricular function in patients with anorexia nervosa by means of pulsed tissue Doppler imaging. METHODS:A total of 20 females (age 22.4+/-4.3 years) with overt anorexia nervosa, 20 match...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2004.03.006
更新日期:2005-05-11 00:00:00
abstract:BACKGROUND:In the SURVIVE trial, including 1327 acute heart failure patients, no statistically significant difference between levosimendan and dobutamine in the 180-day all-cause mortality was seen. Country-specific differences in outcome were, however, present. In the Finnish sub-population in fact, mortality was sign...
journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2016.04.064
更新日期:2016-07-15 00:00:00
abstract:BACKGROUND:Heparin is an important medication in the treatment of patients with unstable angina pectoris. We designed an observational study to compare the effects of standard heparin (SH) with low molecular weight heparin (LMWH) on vascular endothelial growth factor (VEGF) levels in patients undergoing coronary artery...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2003.03.022
更新日期:2004-04-01 00:00:00
abstract::Cardiac pacing from either endocardial or transesophageal sites has proven useful in termination of sustained supraventricular tachycardia in children. In two patients we demonstrated the efficacy of external pacing in the termination of sustained supraventricular tachycardia. The ease and apparent safety of the techn...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(90)90056-b
更新日期:1990-08-01 00:00:00
abstract:BACKGROUND:Alterations in coronary vasomotor tone may participate in the pathogenesis of acute myocardial infarction (AMI). Vascular ATP-sensitive K(+) (KATP) channels, formed by Kir6.x/SUR2B, are key regulators of coronary tone and mutations in cardiac (Kir6.2/SUR2A) KATP channels result in heart disease. Here we expl...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2013.04.210
更新日期:2013-10-09 00:00:00
abstract:INTRODUCTION:Sports activity has been associated with the development of atrial arrhythmias. Atrial fibrillation (AF) is frequently observed after successful ablation for atrial flutter. Sports activity as a risk factor for AF development after flutter ablation has not been studied. METHODS:We analyzed outcome in 137 ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2005.02.043
更新日期:2006-02-08 00:00:00
abstract::Prolonged strenuous endurance exercise (SEE) such as marathon running has recently been associated with potential deleterious cardiac effects, particularly increased risk of atrial fibrillation (AF). This topic is medically important due to the increasing number of participants in SEE events lasting several hours, inc...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2015.06.014
更新日期:2015-10-15 00:00:00
abstract:AIM:To describe various factors associated with the very long-term prognosis for patients with a very small or an unconfirmed acute myocardial infarction (AMI).
METHODS:Patients below 76 years of age, hospitalized due to suspected AMI who either developed a very small AMI (enzyme elevation journal_title:International journal of cardiology pub_type: 杂志文章 doi:10.1016/s0167-5273(01)00383-7 更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Cardiac myxomas (CMs) are a major primary heart tumor which often causes unexpected symptoms or sudden death. Among CMs, biatrial myxomas are even rare. This study was designed to investigate the clinical characteristics and surgical treatment of 5 cases with biatrial myxoma, to summarize the treatment exper...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.11.171
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Pulmonary arterial hypertension (PAH) in systemic sclerosis (SS) identifies a poor prognosis subset of patients. Recent studies suggested a "metabolic theory" on the development of pulmonary arterial hypertension. On this basis we performed a metabolomic study in order to evaluate whether differences in pulm...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2017.04.024
更新日期:2017-08-15 00:00:00
abstract:BACKGROUND:We were to evaluate the effect of Valsalva maneuver with comparison to preload reduction by nitroglycerin (NTG) to predict intraventricular obstruction (IVO) during dobutamine stress echocardiography (DSE) in patients with hypertension. METHODS:A total of 38 hypertensive patients (mean age 66.0±9.9 years; 3...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2009.03.069
更新日期:2010-10-29 00:00:00
abstract::Coronary artery bypass grafting without cardiopulmonary bypass (CPB) is now an accepted technique of myocardial revascularization in a special subset of patients. This paper presents our total experience in 1761 cases operated on since September 1981 until April 1997 out of a total of 9164 patients revascularized with...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(97)00219-2
更新日期:1997-12-01 00:00:00
abstract:BACKGROUND:Study aimed to describe the extent and the temporal profile of cardiac remodeling after atrial septal defect closure in the adult. METHODS:Prospective and longitudinal echocardiographic assessment of right and left heart size before and after (1 day-1 week/1/4/12 months) surgical or catheter-based atrial se...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2005.05.042
更新日期:2006-04-14 00:00:00
abstract::The effects of high dose captopril, within the therapeutic range, on autonomic activity are unknown in those with normal cardiovascular function. Thus the study aims were to assess the effects of high dose captopril on autonomic function in mice. Autonomic activity was measured using heart rate variability (HRV). ECG ...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2008.03.082
更新日期:2009-08-14 00:00:00