Abstract：
:The first schizogony of Eimeria bovis takes place in lymphatic endothelial cells of the ileum, resulting in the formation of macroschizonts within 2-3 weeks. In this study, we analyse early cellular immune responses to infected host cells on the basis of peripheral blood mononuclear cell (PBMC) adhesion on and transmigration through infected bovine umbilical vein endothelial cell (BUVEC) monolayers. Adhesion of PBMC was upregulated by an E. bovis infection. Most marked effects were observed 1 day p.i.; thereafter, PBMC adhesion declined reaching control levels from day 8 p.i. onward. CD8(+) T cells adhered more frequently to infected BUVEC (42%) than CD4(+) T cells (25%). About one third of attached PBMC were represented by gammadelta-TCR(+) T cells. Adhesion of T cells was not restricted to parasitised host cells, but occurred almost equally on non-infected BUVEC within the same monolayer. Furthermore, we found moderately enhanced levels of PBMC transmigration through infected BUVEC monolayers, in particular on day 2 p.i. The data presented here suggest that E. bovis infection of BUVEC induces endothelial cell-derived proinflammatory reactions, which appear suitable for the initiation of both adaptive and innate immune responses.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Taubert A,Zahner H,Hermosilla Cdoi
10.1007/s00436-007-0517-8subject
Has Abstractpub_date
2007-08-01 00:00:00pages
591-8issue
3eissn
0932-0113issn
1432-1955journal_volume
101pub_type
杂志文章abstract：:Biosynthesized nanoparticles have been achieved using environmentally acceptable plant extract and eco-friendly reducing and capping agents. The present study was based on assessments of the larvicidal activities to determine the efficacies of synthesized silver nanoparticles (AgNPs) using aqueous leaf extract of Vinc...
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journal_title：Parasitology research
pub_type： 杂志文章
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journal_title：Parasitology research
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更新日期：2009-10-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章,随机对照试验
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更新日期：2007-02-01 00:00:00
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更新日期：2015-08-01 00:00:00
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更新日期：2003-08-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
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更新日期：2013-07-01 00:00:00
abstract：:Microsporidia is a group of spore-forming microorganisms with zoonotic potential. This study aimed to compare intestinal microsporidia infections in cat owners and non-pet owners. In total, 210 fecal samples were collected from indoor cats, cat owners, and non-pet owners. DNA extraction was performed and the small sub...
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更新日期：2020-06-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
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更新日期：2008-04-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-006-0356-z
更新日期：2007-04-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00531092
更新日期：1987-01-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00932242
更新日期：1993-01-01 00:00:00
abstract：:A free-living soil amoeba Thecamoeba quadrilineata (Carter, 1856) Lepşi, 1960 (Amoebozoa: Thecamoebidae) was isolated from endozoic conditions for the first time. Presence of amoebae was detected after 4 days following inoculation of the gut of the earthworm Lumbricus terrestris on agar plate with Escherichia coli. On...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-019-06207-y
更新日期：2019-03-01 00:00:00
