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Oxazolidinone susceptibility patterns for 2005: International Report from the Zyvox Annual Appraisal of Potency and Spectrum Study.

Abstract：

:The international (non-USA) ZAAPS Program has accumulated 4 years of linezolid resistance surveillance results tracking infections caused by organisms with evolving resistance profiles. The major organism groups monitored were: Staphylococcus aureus and coagulase-negative staphylococci (including methicillin [oxacillin]-resistant strains), enterococci (including vancomycin-resistant [VRE] strains), Streptococcus pneumoniae (including multidrug-resistant [MDR] strains), viridans group streptococci and beta-haemolytic streptococci (4209 isolates overall). No linezolid-resistant strains were detected from the 16 monitored nations participating in 2005, consistent with previously reported 2002-2004 results. Linezolid remains highly active against Gram-positive strains including MRSA (MIC(90), 2mg/L). With MDR in Gram-positive organisms increasing in prevalence, continued surveillance of linezolid appears to be prudent practice as linezolid becomes more widely prescribed for these difficult-to-treat infections.

journal_name

Int J Antimicrob Agents

journal_title

International journal of antimicrobial agents

authors

Ross JE,Fritsche TR,Sader HS,Jones RN

doi

10.1016/j.ijantimicag.2006.09.025

subject

Has Abstract

pub_date

2007-03-01 00:00:00

pages

295-301

issue

3

eissn

0924-8579

issn

1872-7913

pii

S0924-8579(06)00470-5

journal_volume

29

pub_type

杂志文章

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