Survey of extended-spectrum beta-lactamases in Escherichia coli isolates from a Portuguese hospital and characterisation of a novel class 1 integron (In60A) carrying the blaCTX-M-9 gene.

Abstract:

:Between November 2001 and November 2004, 231 Escherichia coli isolates resistant to beta-lactam antibiotics were identified. In 14 isolates, bla(TEM-24) (2 isolates), bla(TEM-52) (5 isolates) and bla(TEM-26) (7 isolates) were identified. In 145 E. coli isolates with the same M13 fingerprinting profile and the same resistance phenotype, the bla(CTX-M-15) gene was found in association with an insertion sequence ISEcp1. The bla(CTX-M-2) gene was identified in one E. coli isolate (290HSM), and in other E. coli isolate (246HSM) the bla(CTX-M-9) gene was contained in a new complex sul1-type class 1 integron (named In60A). This is the first report of three cefotaximases (CTX-M-15, CTX-M-2 and CTX-M-9) in E. coli isolates from a Portuguese hospital.

authors

Brizio A,Vasco S,Gonçalves AR,Lito LM,Cristino JM,Salgado MJ,Duarte A

doi

10.1016/j.ijantimicag.2006.08.002

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

320-4

issue

4

eissn

0924-8579

issn

1872-7913

pii

S0924-8579(06)00293-7

journal_volume

28

pub_type

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