Burden of community-onset bloodstream infection: a population-based assessment.


:Although community-onset bloodstream infection (BSI) is recognized to be a major cause of morbidity and mortality, there is a paucity of population-based studies defining its overall burden. We conducted population-based laboratory surveillance for all community-onset BSI in the Calgary Health Region during 2000-2004. A total of 4467 episodes of community-onset BSI were identified for an overall annual incidence of 81.6/100,000. The three species, Escherichia coli, Staphylococcus aureus, and Streptococcus pneumoniae were responsible for the majority of community-onset BSI; they occurred at annual rates of 25.8, 13.5, and 10.1/100,000, respectively. Overall 3445/4467 (77%) episodes resulted in hospital admission representing 0.7% of all admissions to major acute care hospitals. The subsequent hospital length of stay was a median of 9 (interquartile range, 5-15) days; the total days of acute hospitalization attributable to community-onset BSI was 51,146 days or 934 days/100,000 annually. Four hundred and sixty patients died in hospital for a case-fatality rate of 13%. Community-onset BSI is common and has a major patient and societal impact. These data support further efforts to reduce the burden of community-onset BSI.


Epidemiol Infect


Laupland KB,Gregson DB,Flemons WW,Hawkins D,Ross T,Church DL




Has Abstract


2007-08-01 00:00:00














  • High prevalence of hepatitis C (HCV) in the emergency department (ED) of a London hospital: should we be screening for HCV in ED attendees?

    abstract::An unlinked anonymous study was conducted to estimate the prevalence of hepatitis C virus (HCV) infection in emergency department (ED) attendees at a London Hospital. Nine hundred and ninety-seven samples collected over a 12-day period were tested for HCV antibody (Ab) and reactive samples were further tested for HCV ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Orkin C,Leach E,Flanagan S,Wallis E,Ruf M,Foster GR,Tong CY

    更新日期:2015-10-01 00:00:00

  • Assessment of neonatal tetanus elimination in an African setting by lot quality assurance cluster sampling (LQA-CS).

    abstract::Neonatal tetanus (NT) elimination, < 1 case per 1,000 live births (LB), was assessed at district level in Zimbabwe using a combined lot quality assurance-cluster sampling survey (LQA-CS). Three of the highest risk districts were selected. NT was considered eliminated if fewer than a specified number of NT deaths (prox...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Cotter B,Bremer V,Stroh G,Msambichaka K,Mabuzane E,Munyoro M,Shirehwa F,Biellik R,Birmingham M

    更新日期:2003-04-01 00:00:00

  • Molecular identification of pathogenicity genes and ERIC types in Vibrio cholerae O1 epidemic strains from Mozambique.

    abstract::The phenotypic and genotypic profiles of the V. cholerae strains causing the Mozambican 1997-8 epidemic were characterized to provide a reference for comparison with other epidemic strains. A total of 75 strains of V. cholerae O1 isolated in different provinces, were analysed. Strains were characterized by PCR for det...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Folgosa E,Mastrandrea S,Cappuccinelli P,Uzzau S,Rappelli P,Brian MJ,Colombo MM

    更新日期:2001-08-01 00:00:00

  • Genetic relationships between foot-and-mouth disease type Asia 1 viruses.

    abstract::The sequence of 165 nucleotides at the 3' end of the 1D (VP1) gene of foot-and-mouth disease (FMD) virus was determined for 44 type Asia 1 strains isolated from throughout Asia between 1954-92. Analysis of the relationships between the virus genomes showed epidemiological links not previously evident. The possible ori...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Ansell DM,Samuel AR,Carpenter WC,Knowles NJ

    更新日期:1994-02-01 00:00:00

  • Rotavirus detection by dot blot hybridization assay using a non-radioactive synthetic oligodeoxynucleotide probe.

    abstract::A synthetic oligodeoxynucleotide of 40 nucleotides corresponding to nucleotides 33-72 of the gene coding for the viral protein VP7 of rotavirus, was used as a nucleic acid probe to develop a non-radioactive hybridization method for rotavirus detection. The probe was labelled at the 3' end with biotin-7-dATP. The sensi...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Fernández J,Sandino A,Yudelevich A,Avendaño LF,Venegas A,Hinrichsen V,Spencer E

    更新日期:1992-02-01 00:00:00

  • Serological diagnosis of leishmaniasis: on detecting infection as well as disease.

    abstract::Serological tests are very frequently used in epidemiological surveys of leishmaniasis and other parasitoses. Their sensitivity and specificity are generally defined with respect to parasitism and disease, rather than infection. The reason is that known positives are those individuals most likely to yield parasites, o...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Dye C,Vidor E,Dereure J

    更新日期:1993-06-01 00:00:00

  • Dynamics of Salmonella transmission on a British pig grower-finisher farm: a stochastic model.

    abstract::Previous modelling studies have estimated that between 1% and 10% of human salmonella infections are attributable to pig meat consumption. In response to this food safety threat the British pig industry have initiated a salmonella monitoring programme. It is anticipated that this programme will contribute to achieving...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Hill AA,Snary EL,Arnold ME,Alban L,Cook AJ

    更新日期:2008-03-01 00:00:00

  • A re-evaluation of the impact of temperature and climate change on foodborne illness.

    abstract::The effects of temperature on reported cases of a number of foodborne illnesses in England and Wales were investigated. We also explored whether the impact of temperature had changed over time. Food poisoning, campylobacteriosis, salmonellosis, Salmonella Typhimurium infections and Salmonella Enteritidis infections we...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Lake IR,Gillespie IA,Bentham G,Nichols GL,Lane C,Adak GK,Threlfall EJ

    更新日期:2009-11-01 00:00:00

  • Molecular epidemiology of recent United Kingdom isolates of Neisseria meningitidis serogroup C.

    abstract::The genomes of 34 recent United Kingdom isolates of Neisseria meningitidis serogroup C were examined by restriction enzyme digestion and by conventional and pulsed-field gel electrophoresis (PFGE). Strains were assigned to groups on the basis of the Dice similarity coefficient; strains with values of > 92% were consid...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Yakubu DE,Abadi FJ,Pennington TH

    更新日期:1994-08-01 00:00:00

  • Application of ribotyping and IS200 fingerprinting to distinguish the five Salmonella serotype O6,7:c:1,5 groups: Choleraesuis sensu stricto, Choleraesuis var. Kunzendorf, Choleraesuis var. Decatur, Paratyphi C, and Typhisuis.

    abstract::Sixty-seven strains of the five described Salmonella serotypes having antigens 6,7:c:1,5, that is S. enterica serotype Choleraesuis sensu stricto, Choleraesuis var. Kunzendorf, Choleraesuis var. Decatur, Paratyphi C, and Typhisuis, were examined for 16S rrn profile ribotype, presence of IS200 and phenotypic characters...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Uzzau S,Hovi M,Stocker BA

    更新日期:1999-08-01 00:00:00

  • High intensities of population movement were associated with high incidence of COVID-19 during the pandemic.

    abstract::Increased population movements and increased mobility made it possible for severe acute respiratory syndrome coronavirus 2, which is mainly spread by respiratory droplets, to spread faster and more easily. This study tracked and analysed the development of the coronavirus 2019 (COVID-19) outbreak in the top 100 cities...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Yang H,Chen D,Jiang Q,Yuan Z

    更新日期:2020-08-03 00:00:00

  • Bancroftian filariasis in Pondicherry, south India: 2. Epidemiological evaluation of the effect of vector control.

    abstract::This article examines the evaluation of a bancroftian filariasis control programme undertaken in Pondicherry from 1981-5. Integrated vector management was applied in one half of the town, and routine operations under the national programme (larviciding and chemotherapy) continued in the comparison area. The programme ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Subramanian S,Pani SP,Das PK,Rajagopalan PK

    更新日期:1989-12-01 00:00:00

  • Prevalence of the genes for shigella enterotoxins 1 and 2 among clinical isolates of shigella in Israel.

    abstract::Two enterotoxins, shigella enterotoxin 1 (SHET1) and shigella enterotoxin 2 (SHET2) have been recently characterized and are believed to play a role in the clinical manifestation of shigellosis. One hundred and twenty-one isolates of Shigella spp. of 13 different serotypes and variants and 10 isolates of enteroinvasiv...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Yavzori M,Cohen D,Orr N

    更新日期:2002-06-01 00:00:00

  • A beef-associated outbreak of Salmonella Typhimurium DT104 in The Netherlands with implications for national and international policy.

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    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Kivi M,Hofhuis A,Notermans DW,Wannet WJ,Heck ME,Van De Giessen AW,Van Duynhoven YT,Stenvers OF,Bosman A,Van Pelt W

    更新日期:2007-08-01 00:00:00

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    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Donald FE,Slack RC,Colman G

    更新日期:1991-06-01 00:00:00

  • The source of Yersinia spp. in pasteurized milk: an investigation at a dairy.

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    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Greenwood MH,Hooper WL,Rodhouse JC

    更新日期:1990-06-01 00:00:00

  • Maternal antibody to hepatitis B core antigen detected in dried neonatal blood spot samples.

    abstract::Despite Department of Health recommendations, universal antenatal testing for hepatitis B virus (HBV) is not performed throughout Scotland. We describe the evaluation of an assay to document past or present infection with HBV, by identifying maternal antibody in routine Guthrie dried neonatal blood spot samples taken ...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Tappin DM,Greer K,Cameron S,Kennedy R,Brown AJ,Girdwood RW

    更新日期:1998-10-01 00:00:00

  • Indirect protection obtained by Haemophilus influenzae type b vaccination: analysis in a structured population model.

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    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Leino T,Takala T,Auranen K,Mäkelä PH,Takala AK

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  • Pathogen burden and cortisol profiles over the day.

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    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Steptoe A,Gylfe A,Shamaei-Tousi A,Bergstrom S,Henderson B

    更新日期:2009-12-01 00:00:00

  • A comparison of gastroenteritis in a general practice-based study and a community-based study.

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    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: de Wit MA,Kortbeek LM,Koopmans MP,de Jager CJ,Wannet WJ,Bartelds AI,van Duynhoven YT

    更新日期:2001-12-01 00:00:00

  • The effect of distance on observed mortality, childhood pneumonia and vaccine efficacy in rural Gambia.

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    pub_type: 杂志文章


    authors: Zaman SM,Cox J,Enwere GC,Bottomley C,Greenwood BM,Cutts FT

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  • An outbreak of viral gastroenteritis associated with adequately prepared oysters.

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    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Chalmers JW,McMillan JH

    更新日期:1995-08-01 00:00:00

  • Widespread Legionella pneumophila contamination of dental stations in a dental school without apparent human infection.

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    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Oppenheim BA,Sefton AM,Gill ON,Tyler JE,O'Mahony MC,Richards JM,Dennis PJ,Harrison TG

    更新日期:1987-08-01 00:00:00

  • Host-microflora interaction in systemic lupus erythematosus (SLE): colonization resistance of the indigenous bacteria of the intestinal tract.

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    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Apperloo-Renkema HZ,Bootsma H,Mulder BI,Kallenberg CG,van der Waaij D

    更新日期:1994-04-01 00:00:00

  • Most Campylobacter subtypes from sporadic infections can be found in retail poultry products and food animals.

    abstract::The subtypes of Campylobacter isolates from human infections in two Danish counties were compared to isolates from retail food samples and faecal samples from chickens, pigs and cattle. During a 1-year period, 1285 Campylobacter isolates from these sources were typed by two methods: 'Penner' heat-stable serotyping and...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Nielsen EM,Fussing V,Engberg J,Nielsen NL,Neimann J

    更新日期:2006-08-01 00:00:00

  • The speciation and subtyping of campylobacter isolates from sewage plants and waste water from a connected poultry abattoir using molecular techniques.

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    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Koenraad PM,Ayling R,Hazeleger WC,Rombouts FM,Newell DG

    更新日期:1995-12-01 00:00:00

  • Measles, mumps, rubella and VZV: importance of serological testing of vaccine-preventable diseases in young adults living with HIV in Germany.

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    journal_title:Epidemiology and infection

    pub_type: 杂志文章,多中心研究


    authors: Schwarze-Zander C,Draenert R,Lehmann C,Stecher M,Boesecke C,Sammet S,Wasmuth JC,Seybold U,Gillor D,Wieland U,Kümmerle T,Strassburg CP,Mankertz A,Eis-Hübinger AM,Jäger G,Fätkenheuer G,Bogner JR,Rockstroh JK,Vehreschild

    更新日期:2017-01-01 00:00:00

  • Assessment of areas at increased risk for poliovirus circulation in Ecuador.

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    journal_title:Epidemiology and infection

    pub_type: 杂志文章,多中心研究


    authors: Dayan GH,Rodríguez R,Vinjé J,Vásconez N,Cáceres V,Gregoricus N,Sobsey M,Landaverde M

    更新日期:2004-10-01 00:00:00

  • Impact of respiratory virus infection in patients with chronic chest disease.

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    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Wiselka MJ,Kent J,Cookson JB,Nicholson KG

    更新日期:1993-10-01 00:00:00

  • Bartonella clarridgeiae and Bartonella vinsonii subsp. berkhoffii exposure in captive wild canids in Brazil.

    abstract::SUMMARY Wild canids are potential hosts for numerous species of Bartonella, yet little research has been done to quantify their infection rates in South America. We sought to investigate Bartonella seroprevalence in captive wild canids from 19 zoos in São Paulo and Mato Grosso states, Brazil. Blood samples were collec...

    journal_title:Epidemiology and infection

    pub_type: 杂志文章


    authors: Fleischman DA,Chomel BB,Kasten RW,André MR,Gonçalves LR,Machado RZ

    更新日期:2015-02-01 00:00:00