Abstract:
:Magnetic resonance imaging (MRI) reconstruction techniques are often validated with signal-to-noise ratio (SNR), contrast-to-noise ratio, and mean-to-standard-deviation ratio measured on example images. We present human and model observers as a novel approach to evaluating reconstructions for low-SNR magnetic resonance (MR) images. We measured human and channelized Hotelling observers in a two-alternative forced-choice signal-known-exactly detection task on synthetic MR images. We compared three reconstructions: magnitude, wavelet-based denoising, and phase-corrected real. Human observers performed approximately equally using all three reconstructions. The model observer showed very close agreement with the humans over the range of images. These results contradict previous predictions in the literature based on SNR. Thus, we propose that human observer studies are important for validating MRI reconstructions. The model's performance indicates that it may provide an alternative to human studies.
journal_name
IEEE Trans Med Imagingjournal_title
IEEE transactions on medical imagingauthors
Tisdall MD,Atkins MSdoi
10.1109/TMI.2006.881374subject
Has Abstractpub_date
2006-11-01 00:00:00pages
1510-7issue
11eissn
0278-0062issn
1558-254Xjournal_volume
25pub_type
杂志文章abstract::Optical coherence tomography (OCT) is a well-established image modality in ophthalmology and used daily in the clinic. Automatic evaluation of such datasets requires an accurate segmentation of the retinal cell layers. However, due to the naturally low signal to noise ratio and the resulting bad image quality, this ta...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2012.2225152
更新日期:2013-03-01 00:00:00
abstract::Conventional ultrasound imaging is based on the scattering of sound from inhomogeneities in the density and the speed of sound and is often used in medicine to resolve pathologic compared to normal tissue. Here we demonstrate a difference-frequency ultrasound (dfUS) imaging method that is based on the interaction of t...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2019.2957280
更新日期:2020-05-01 00:00:00
abstract::Short-echo-time (TE) proton magnetic resonance spectroscopic imaging (MRSI) allows for simultaneously mapping a number of molecules in the brain, and has been recognized as an important tool for studying in vivo biochemistry in various neuroscience and disease applications. However, separation of the metabolite and ma...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2020.3048933
更新日期:2021-01-04 00:00:00
abstract::This editorial introduces the Special Issue on Simulation and Synthesis in Medical Imaging. In this editorial, we define so-far ambiguous terms of simulation and synthesis in medical imaging. We also briefly discuss the synergistic importance of mechanistic (hypothesis-driven) and phenomenological (data-driven) models...
journal_title:IEEE transactions on medical imaging
pub_type: 社论
doi:10.1109/TMI.2018.2800298
更新日期:2018-03-01 00:00:00
abstract::Diffusion tensor imaging is widely used in brain connectivity research. As more and more studies recruit large numbers of subjects, it is important to design registration methods which are not only theoretically rigorous, but also computationally efficient. However, the requirement of reorienting diffusion tensors com...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2013.2274051
更新日期:2014-05-01 00:00:00
abstract::Recently, deep neural networks have been widely and successfully applied in computer vision tasks and have attracted growing interest in medical imaging. One barrier for the application of deep neural networks to medical imaging is the need for large amounts of prior training pairs, which is not always feasible in cli...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2018.2888491
更新日期:2019-07-01 00:00:00
abstract::Active shape models bear a great promise for model-based medical image analysis. Their practical use, though, is undermined due to the need to train such models on large image databases. Automatic building of point distribution models (PDMs) has been successfully addressed and a number of autolandmarking techniques ar...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2008.2004819
更新日期:2008-11-01 00:00:00
abstract::Radiation therapy (RT) has been widely used as a powerful treatment tool to address cancerous tissues because of its ability to control cell growth. Its ionizing radiation damages the DNA of cancerous tissues, leading to cell death. Medical imaging, however, still has limitations regarding the reliability of its asses...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2019.2913766
更新日期:2019-12-01 00:00:00
abstract::Dynamic contrast-enhanced magnetic resonance imaging (MRI) is a promising tool in the evaluation of tumor physiology. From rapidly acquired images and a model for contrast agent pharmacokinetics, physiological parameters are derived. One pharmacokinetic model, the tissue homogeneity model, enables estimation of both b...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2009.2016212
更新日期:2009-09-01 00:00:00
abstract::A major issue in telepathology is the extremely large and growing size of digitized "virtual" slides, which can require several gigabytes of storage and cause significant delays in data transmission for remote image interpretation and interactive visualization by pathologists. Compression can reduce this massive amoun...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2010.2077308
更新日期:2011-02-01 00:00:00
abstract::The aim of this work is the evaluation of the design for a nonconventional PET scanner, the voxel imaging PET (VIP), based on pixelated room-temperature CdTe detectors yielding a true 3-D impact point with a density of 450 channels/cm(3), for a total 6 336 000 channels in a seamless ring shaped volume. The system is s...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2013.2284657
更新日期:2014-02-01 00:00:00
abstract::Image reconstruction in low-count PET is particularly challenging because gammas from natural radioactivity in Lu-based crystals cause high random fractions that lower the measurement signal-to-noise-ratio (SNR). In model-based image reconstruction (MBIR), using more iterations of an unregularized method may increase ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2020.2998480
更新日期:2020-11-01 00:00:00
abstract::A radial search technique is presented for detecting skin tumor borders in clinical dermatology images. First, it includes two rounds of radial search based on the same tumor center. The first-round search is independent, and the second-round search is knowledge-based tracking. Then a rescan with a new center is used ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.896789
更新日期:2000-11-01 00:00:00
abstract::A novel image reconstruction algorithm has been developed and demonstrated for fluorescence-enhanced frequency-domain photon migration (FDPM) tomography from measurements of area illumination with modulated excitation light and area collection of emitted fluorescence light using a gain modulated image-intensified char...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/tmi.2004.839359
更新日期:2005-02-01 00:00:00
abstract::Spatially variant longitudinal aliasing plagues most volumes reconstructed from single-slice helical computed tomography data, and its presence can degrade resolution and distort image structures. We have recently developed a Fourier-based approach to longitudinal interpolation in helical computed tomography that can,...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2002.803104
更新日期:2002-08-01 00:00:00
abstract::It is known that when the maximum likelihood estimator (MLE) algorithm passes a certain point, it produces images that begin to deteriorate. We propose a quantitative criterion with a simple probabilistic interpretation that allows the user to stop the algorithm just before this effect begins. The MLE algorithm search...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.1987.4307849
更新日期:1987-01-01 00:00:00
abstract::Simulations provide a way of generating data where ground truth is known, enabling quantitative testing of image processing methods. In this paper, we present the construction of 20 realistic digital brain phantoms that can be used to simulate medical imaging data. The phantoms are made from 20 normal adults to take i...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2006.883453
更新日期:2006-11-01 00:00:00
abstract::Adolescence is a transitional period between the childhood and adulthood with physical changes, as well as increasing emotional development. Studies have shown that the emotional sensitivity is related to a second period of rapid brain growth. However, there is little focus on the trend of brain development during thi...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2019.2926667
更新日期:2020-02-01 00:00:00
abstract::An n-dimensional (n-D) filtered backprojection image reconstruction algorithm has been developed and used in the reconstruction of 4-D spectral-spatial magnetic resonance imaging (MRI) data. The algorithm uses n-1 successive stages of 2-D filtered backprojection to reconstruct an n-D image. This approach results in a ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.387718
更新日期:1995-01-01 00:00:00
abstract::We present two types of globally convergent relaxed ordered subsets (OS) algorithms for penalized-likelihood image reconstruction in emission tomography: modified block sequential regularized expectation-maximization (BSREM) and relaxed OS separable paraboloidal surrogates (OS-SPS). The global convergence proof of the...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2003.812251
更新日期:2003-05-01 00:00:00
abstract::Ultrafast ultrasound imaging using plane or diverging waves, instead of focused beams, has advanced greatly the development of novel ultrasound imaging methods for evaluating tissue functions beyond anatomical information. However, the sonographic signal-to-noise ratio (SNR) of ultrafast imaging remains limited due to...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2017.2781261
更新日期:2018-04-01 00:00:00
abstract::Computerized detection of clustered microcalcifications (MCs) in mammograms often suffers from the occurrence of false positives (FPs), which can vary greatly from case to case. We investigate how to apply statistical estimation to determine the number of FPs that are present in a detected MC lesion. First, we describ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2017.2654799
更新日期:2017-05-01 00:00:00
abstract::For fully characterizing renal cell carcinoma (RCC), information about the 3D tissue microstructure is essential. Histopathology, which represents the current diagnostic gold standard, is destructive and only provides 2D information. 3D X-ray histology endeavors to overcome these limitations by generating 3D data. In ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2019.2952028
更新日期:2020-05-01 00:00:00
abstract::Identification of anatomical features is a necessary step for medical image analysis. Automatic methods for feature identification using conventional pattern recognition techniques typically classify an object as a member of a predefined class of objects, but do not attempt to recover the exact or approximate shape of...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.293916
更新日期:1994-01-01 00:00:00
abstract::The presence of high-density objects remains an open problem in medical CT imaging. Data of projections passing through objects of high density, such as metal implants, are dominated by noise and are highly affected by beam hardening and scatter. Reconstructed images become less diagnostically conclusive because of pr...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2015.2459764
更新日期:2016-01-01 00:00:00
abstract::Mammographic risk scoring has commonly been automated by extracting a set of handcrafted features from mammograms, and relating the responses directly or indirectly to breast cancer risk. We present a method that learns a feature hierarchy from unlabeled data. When the learned features are used as the input to a simpl...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2016.2532122
更新日期:2016-05-01 00:00:00
abstract::Cerebral ischemic stroke causes injury to brain tissue characterized by a complex cascade of neuronal and vascular events. Imaging during the early stages of its development allows prediction of tissue infarction and penumbra so that optimal intervention can be determined in order to salvage brain function impairment....
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2019.2895779
更新日期:2019-06-01 00:00:00
abstract::In this paper, we present a robust approach to the registration of white matter tractographies extracted from diffusion tensor-magnetic resonance imaging scans. The fibers are projected into a high dimensional feature space based on the sequence of their 3-D coordinates. Adaptive mean-shift clustering is applied to ex...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2009.2029097
更新日期:2010-01-01 00:00:00
abstract::We investigate the effects of initial conditions in the iterative maximum-likelihood (ML) reconstruction of fan-beam transmission projection data with truncation. In an iterative ML reconstruction, the estimate of the transmission reconstructed image in the previous iteration is multiplied by some factors to obtain th...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.611352
更新日期:1997-08-01 00:00:00
abstract::We are presenting data from the largest clinical trial on optical tomographic imaging of finger joints to date. Overall we evaluated 99 fingers of patients affected by rheumatoid arthritis (RA) and 120 fingers from healthy volunteers. Using frequency-domain imaging techniques we show that sensitivities and specificiti...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2011.2135374
更新日期:2011-10-01 00:00:00