Abstract:
:Optical coherence tomography (OCT) is a well-established image modality in ophthalmology and used daily in the clinic. Automatic evaluation of such datasets requires an accurate segmentation of the retinal cell layers. However, due to the naturally low signal to noise ratio and the resulting bad image quality, this task remains challenging. We propose an automatic graph-based multi-surface segmentation algorithm that internally uses soft constraints to add prior information from a learned model. This improves the accuracy of the segmentation and increase the robustness to noise. Furthermore, we show that the graph size can be greatly reduced by applying a smart segmentation scheme. This allows the segmentation to be computed in seconds instead of minutes, without deteriorating the segmentation accuracy, making it ideal for a clinical setup. An extensive evaluation on 20 OCT datasets of healthy eyes was performed and showed a mean unsigned segmentation error of 3.05 ±0.54 μm over all datasets when compared to the average observer, which is lower than the inter-observer variability. Similar performance was measured for the task of drusen segmentation, demonstrating the usefulness of using soft constraints as a tool to deal with pathologies.
journal_name
IEEE Trans Med Imagingjournal_title
IEEE transactions on medical imagingauthors
Dufour PA,Ceklic L,Abdillahi H,Schröder S,De Dzanet S,Wolf-Schnurrbusch U,Kowal Jdoi
10.1109/TMI.2012.2225152subject
Has Abstractpub_date
2013-03-01 00:00:00pages
531-43issue
3eissn
0278-0062issn
1558-254Xjournal_volume
32pub_type
杂志文章abstract::Almost all magnetic resonance electrical impedance tomography (MREIT) reconstruction algorithms proposed to date assume isotropic conductivity in order to simplify the image reconstruction. However, it is well known that most of biological tissues have anisotropic conductivity values. In this study, four novel anisotr...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2011.2171192
更新日期:2012-03-01 00:00:00
abstract::Computed tomography (CT) has become the new reference standard for quantification of emphysema. The most popular measure of emphysema derived from CT is the pixel index (PI), which expresses the fraction of the lung volume with abnormally low intensity values. As PI is calculated from a single, fixed threshold on inte...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2006.871545
更新日期:2006-04-01 00:00:00
abstract::We describe the efficient algebraic reconstruction (EAR) method, which applies to cone-beam tomographic reconstruction problems with a circular symmetry. Three independant steps/stages are presented, which use two symmetries and a factorization of the point spread functions (PSFs), each reducing computing times and ev...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2005.861707
更新日期:2006-02-01 00:00:00
abstract::Radio-frequency current density imaging (RF-CDI) is an imaging technique that noninvasively measures current density distribution at the Larmor frequency utilizing magnetic resonance imaging (MRI). Previously implemented RF-CDI techniques were only able to image a single slice transverse to the static magnetic field B...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2008.2012161
更新日期:2009-07-01 00:00:00
abstract::In positron emission tomography (PET) image reconstruction, the Bayesian framework with various regularization terms has been implemented to constrain the radio tracer distribution. Varying the regularizing weight of a maximum a posteriori (MAP) algorithm specifies a lower bound of the tradeoff between variance and sp...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2018.2803681
更新日期:2018-06-01 00:00:00
abstract::Tomographic reconstruction from positron emission tomography (PET) data is an ill-posed problem that requires regularization. An attractive approach is to impose an l(1) -regularization constraint, which favors sparse solutions in the wavelet domain. This can be achieved quite efficiently thanks to the iterative algor...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2008.923698
更新日期:2008-01-01 00:00:00
abstract::Visual estimation of coronary obstruction severity from angiograms suffers from poor inter- and intraobserver reproducibility and is often inaccurate. In spite of the widely recognized limitations of visual analysis, automated methods have not found widespread clinical use, in part because they too frequently fail to ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.370412
更新日期:1995-01-01 00:00:00
abstract::We describe a matched subspace detection algorithm to assist in the detection of small tumors in dynamic positron emission tomography (PET) images. The algorithm is designed to differentiate tumors from background using the time activity curves (TACs) that characterize the uptake of PET tracers. TACs are modeled using...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2008.929105
更新日期:2009-02-01 00:00:00
abstract::Three-dimensional (3-D) reconstructions of coronary bypass grafts performed from X-ray angiographic images may become increasingly important for the investigation of damaging mechanical stresses imposed to these vessels by the cyclic movement of the heart. Contrary to what we had experienced with coronary arteries, ap...
journal_title:IEEE transactions on medical imaging
pub_type: 信件
doi:10.1109/42.875203
更新日期:2000-07-01 00:00:00
abstract::The classification of 3 common breast lesions, fibroadenomas, cysts, and cancers, was achieved using computerized image analysis of tumor shape in conjunction with patient age. The process involved the digitization of 69 mammographic images using a video camera and a commercial frame grabber on a PC-based computer sys...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.251116
更新日期:1993-01-01 00:00:00
abstract::A system for digital flashing tomosynthesis (DFTS) consists of four ECG-gated simultaneously flashed X-ray tubes, a 14-in image intensifier, a unit for digital subtraction angiography (DSA), a PC-hosted transputer network for three-dimensional (3-D) reconstruction as well as for quantitative coronary angiography and v...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.232261
更新日期:1993-01-01 00:00:00
abstract::An n-dimensional (n-D) filtered backprojection image reconstruction algorithm has been developed and used in the reconstruction of 4-D spectral-spatial magnetic resonance imaging (MRI) data. The algorithm uses n-1 successive stages of 2-D filtered backprojection to reconstruct an n-D image. This approach results in a ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.387718
更新日期:1995-01-01 00:00:00
abstract::When more than two elemental materials are present in a given object, material quantification may not be robust and accurate when the routine two-material decomposition scheme in current dual energy CT imaging is employed. In this work, we present an innovative scheme to accomplish accurate three-material decompositio...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2020.2990347
更新日期:2020-11-01 00:00:00
abstract::An algorithm is developed for electrical impedance tomography (EIT) of finite cylinders with general cross-sectional boundaries and translationally uniform conductivity distributions. The electrodes for data collection are assumed to be placed around a cross-sectional plane; therefore, the axial variation of the bound...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.52982
更新日期:1990-01-01 00:00:00
abstract::The three-dimensional cardiac electrical imaging (3DCEI) technique was previously developed to estimate the initiation site(s) of cardiac activation and activation sequence from the noninvasively measured body surface potential maps (BSPMs). The aim of this study was to develop and evaluate the capability of 3DCEI in ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2012.2202914
更新日期:2012-09-01 00:00:00
abstract::Cardiac resynchronization therapy (CRT) has been shown to improve cardiovascular function in specific patients suffering from heart failure. This procedure still needs to be optimized to overcome the high rate of implanted patients that do not respond to this therapy. We propose in this work a better characterization ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2014.2311694
更新日期:2014-06-01 00:00:00
abstract::A fully automated approach to segmentation of the left and right cardiac ventricles from magnetic resonance (MR) images is reported. A novel multistage hybrid appearance model methodology is presented in which a hybrid active shape model/active appearance model (AAM) stage helps avoid local minima of the matching func...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.925294
更新日期:2001-05-01 00:00:00
abstract::Image reconstruction in low-count PET is particularly challenging because gammas from natural radioactivity in Lu-based crystals cause high random fractions that lower the measurement signal-to-noise-ratio (SNR). In model-based image reconstruction (MBIR), using more iterations of an unregularized method may increase ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2020.2998480
更新日期:2020-11-01 00:00:00
abstract::Mammographic risk scoring has commonly been automated by extracting a set of handcrafted features from mammograms, and relating the responses directly or indirectly to breast cancer risk. We present a method that learns a feature hierarchy from unlabeled data. When the learned features are used as the input to a simpl...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2016.2532122
更新日期:2016-05-01 00:00:00
abstract::Diffusion tensor magnetic resonance imaging (DT-MRI) is capable of providing quantitative insights into tissue microstructure in the brain. An important piece of information offered by DT-MRI is the directional preference of diffusing water molecules within a voxel. Building upon this local directional information, DT...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2008.915663
更新日期:2008-06-01 00:00:00
abstract::In this paper, we show how a dense surface point distribution model of the human face can be computed and demonstrate the usefulness of the high-dimensional shape-space for expressing the shape changes associated with growth and aging. We show how average growth trajectories for the human face can be computed in the a...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2003.814784
更新日期:2003-06-01 00:00:00
abstract::Image interpolation is an important operation that is widely used in medical imaging, image processing, and computer graphics. A variety of interpolation methods are available in the literature. However, their systematic evaluation is lacking. In a previous paper, we presented a framework for the task-independent comp...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.759116
更新日期:1999-02-01 00:00:00
abstract::A good statistical model of speckle formation is useful for designing a good adaptive filter for speckle reduction In ultrasound B-scan images. Previously, statistical models have been used, but they failed to account for the log compression of the echo envelope employed by clinical ultrasound systems. Log-compression...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.544498
更新日期:1996-01-01 00:00:00
abstract::This paper addresses the implementation of image processing and computer vision techniques to automate tracer flow extraction in images obtained by the photochromic dye technique. This task is important in modeled arterial blood flow studies. Currently, it is performed via manual application of B-spline curve fitting....
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.585762
更新日期:1997-06-01 00:00:00
abstract::Fan-beam collimators are used in single photon emission computed tomography to improve the sensitivity for imaging of small organs. The disadvantage of fan-beam collimation is the truncation of projection data surrounding the organ of interest or, in those cases of imaging large patients, of the organ itself producing...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.310886
更新日期:1994-01-01 00:00:00
abstract::Elevated umbilical artery pulsatility is a widely used biomarker for placental pathology leading to intra-uterine growth restriction and, in severe cases, still-birth. It has been hypothesized that placental pathology modifies umbilical artery pulsatility by altering the degree to which the pulse pressure wave, which ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2020.3004511
更新日期:2020-11-01 00:00:00
abstract::Since the invention of diffusion magnetic resonance imaging (dMRI), currently the only established method for studying white matter connectivity in a clinical environment, there has been a great deal of interest in the effects of various pathologies on the connectivity of the brain. As methods for in vivo tractography...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2007.905826
更新日期:2007-11-01 00:00:00
abstract::We propose a joint information approach for automatic analysis of 2D echocardiography (echo) data. The approach combines a priori images, their segmentations and patient diagnostic information within a unified framework to determine various clinical parameters, such as cardiac chamber volumes, and cardiac disease labe...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2016.2593900
更新日期:2017-01-01 00:00:00
abstract::Segmentation-based scores play an important role in the evaluation of computational tools in medical image analysis. These scores evaluate the quality of various tasks, such as image registration and segmentation, by measuring the similarity between two binary label maps. Commonly these measurements blend two aspects ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2012.2216281
更新日期:2012-12-01 00:00:00
abstract::Several techniques based on the three-dimensional (3-D) discrete cosine transform (DCT) have been proposed for volumetric data coding. These techniques fail to provide lossless coding coupled with quality and resolution scalability, which is a significant drawback for medical applications. This paper gives an overview...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/tmi.2003.809582
更新日期:2003-03-01 00:00:00