Relationship between metabolic syndrome components and vascular properties in Japanese type 2 diabetic patients without cardiovascular disease or nephropathy.

Abstract:

:To investigate the effect of metabolic syndrome (MS) components on early atherosclerosis markers, i.e., urinary albumin excretion rate (UAE), pulse wave velocity (PWV), and carotid intima-media thickness (IMT), we studied 536 Japanese patients with type 2 diabetes without cardiovascular disease or nephropathy. The MS definition by ATP III was employed. UAE, PWV, and IMT increased significantly with increasing the number of components even before fulfilling the diagnosis of MS. UAE was significantly influenced by high blood pressure, high triglycerides, and low HDL cholesterol. PWV was significantly increased by high blood pressure. IMT was significantly increased by high blood pressure and abdominal obesity. Multiple regression analysis, including MS components and putative risk factors, indicated that the number of MS components, age and glycosylated HbA1C were independent determinants of UAE, PWV, and IMT. LDL cholesterol and male gender were independent determinants of IMT. In conclusion, UAE, PWV, and IMT increased according to increasing the number of MS in type 2 diabetic patients without cardiovascular disease or diabetic nephropathy. The current observation considering the modifiable factors may help to identify patients who are at high risk of experiencing cardiovascular disease.

authors

Yokoyama H,Kuramitsu M,Kanno S,Tada J,Yokota Y,Kamikawa F

doi

10.1016/j.diabres.2006.06.015

subject

Has Abstract

pub_date

2007-02-01 00:00:00

pages

200-6

issue

2

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(06)00245-2

journal_volume

75

pub_type

杂志文章
  • Ethnicity, race, and clinically significant macular edema in the Veterans Affairs Diabetes Trial (VADT).

    abstract:OBJECTIVE:To determine risk factors in clinically significant macular edema (CSME) and if increased CSME in minorities is due to ethnicity or other factors in the Veterans Affairs Diabetes Trial (VADT). METHODS:CSME prevalence based on 7-field stereo fundus photographs in 1268 patients with type 2 diabetes was related...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2009.08.001

    authors: Emanuele N,Moritz T,Klein R,Davis MD,Glander K,Khanna A,Thottapurathu L,Bahn G,Duckworth W,Abraira C,Veterans Affairs Diabetes Trial Study Group.

    更新日期:2009-11-01 00:00:00

  • Sphingosine-1-phosphate induced vasoconstriction is increased in the isolated perfused kidneys of diabetic rats.

    abstract::We observed that in isolated perfused rat kidneys, sphingosine-1-phosphate produces S1P(2) receptor-mediated vasoconstriction, and this response increased in kidneys of diabetic rats. These results suggest that the antagonists of S1P(2) receptor may have potential as drugs to control diabetes-induced vascular complica...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2011.06.023

    authors: Bautista-Pérez R,Arellano A,Franco M,Osorio H,Coronel I

    更新日期:2011-10-01 00:00:00

  • Optimal range of HbA1c for the prediction of future diabetes: a 4-year longitudinal study.

    abstract:AIM:A glycated hemoglobin (HbA1c) range of 5.7-6.4% has been included as a category of increased risk for diabetes. We evaluated whether or not it is reasonable to apply this HbA1c range to Koreans. METHODS:A retrospective analysis was conducted among subjects who participated in comprehensive health check-ups annuall...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2011.05.028

    authors: Bae JC,Rhee EJ,Lee WY,Park SE,Park CY,Oh KW,Park SW,Kim SW

    更新日期:2011-08-01 00:00:00

  • Beta cell function and response to treatment in Nigerians with Type 2 diabetes mellitus.

    abstract::There are scant data from African populations on the association between beta-cell function and response to treatment with oral hypoglycaemic agents in Type 2 diabetes mellitus (T2DM). Fasting plasma C-peptide (FCP) and glucagon-stimulated C-peptide (GSCP) levels were measured in 116 Nigerians with T2DM at a universit...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2004.12.006

    authors: Oli JM,Adeyemo AA,Okafor GO,Ofoegbu EN,Onyenekwe B,Chukwuka CJ,Chen G,Chen Y,Doumatey AP,Aje TO,Rotimi CN

    更新日期:2005-08-01 00:00:00

  • Cardiovascular autonomic neuropathy, autonomic symptoms and diabetic complications in 674 type 2 diabetes.

    abstract:AIMS:To determine the relationships between cardiovascular autonomic neuropathy (CAN) and autonomic symptoms, clinical parameters and diabetic complications in type 2 diabetes (T2DM). METHODS:The results of autonomic symptoms, clinical parameters, diabetes complications and cardiovascular reflex (CVR) tests of 674 T2D...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2008.08.012

    authors: Chen HT,Lin HD,Won JG,Lee CH,Wu SC,Lin JD,Juan LY,Ho LT,Tang KT

    更新日期:2008-11-01 00:00:00

  • Serum lipoprotein (a) levels in patients with diabetic foot lesions.

    abstract::Our aim was to see the levels of lipoprotein (a) (Lp (a)) in patients with gangrenous or non-gangrenous diabetic foot lesions. Twenty-two patients with gangrenous foot lesions, 11 with non-gangrenous foot lesions and 10 healthy subjects were included in the study. All the patients had similar glycemic control and dura...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2005.06.005

    authors: Unlühizarci K,Muhtaroğlu S,Kabak S,Bayram F,Keleştimur F

    更新日期:2006-02-01 00:00:00

  • The impact of initial antidiabetic agent and use of monitoring agents on prescription costs in newly treated type 2 diabetes: A retrospective cohort analysis.

    abstract:AIMS:To measure the costs associated with the use of antidiabetic agents, monitoring materials and cardiovascular disease (CVD) agents in the management of newly treated type 2 diabetes, and to investigate the factors associated with these costs. METHODS:A population-based retrospective cohort study was conducted usin...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2015.12.020

    authors: Grimes RT,Bennett K,Canavan R,Tilson L,Henman MC

    更新日期:2016-03-01 00:00:00

  • Mortality trends and cause of death in patients with new-onset type 2 diabetes and controls: A 24-year follow-up prospective cohort study.

    abstract:AIMS:Our aim was to assess causes of death and temporal changes in excess mortality among patients with new-onset type 2 diabetes in Skaraborg, Sweden. METHODS:Patients from the Skaraborg Diabetes Register with prospectively registered new-onset type 2 diabetes 1991-2004 were included. Five individual controls matched...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2018.01.038

    authors: Andersson T,Hjerpe P,Carlsson AC,Pivodic A,Wändell P,Manhem K,Bengtsson Boström K

    更新日期:2018-04-01 00:00:00

  • Adherence to postpartum diabetes mellitus screening, do associated pregnancy complications make a difference?

    abstract:AIMS:We aimed to investigate the impact of Gestational Diabetes Mellitus (GDM) complications on compliance with postpartum Diabetes screening. METHODS:A retrospective cohort study was conducted comparing screening rates of women with and without GDM associated complications who delivered at the Soroka University Medic...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2019.107972

    authors: Rotem R,Salem-Yaniv S,Sandler-Rahat H,Yohay D,Sade S,Yahav L,Weintraub AY

    更新日期:2020-01-01 00:00:00

  • The assessment and management of albuminuria in primary care.

    abstract:BACKGROUND:While CKD is a common finding in patients with type 2 diabetes, the clinical response to its identification is often problematic. This study aims to determine the frequency of albuminuria in patients with type 2 diabetes in the primary care setting and examine the factors which influence its management. MET...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2007.10.024

    authors: Thomas MC

    更新日期:2008-04-01 00:00:00

  • Factors predicting the need for insulin therapy in patients with gestational diabetes mellitus.

    abstract:AIM:To determine the possible factors predicting the insulin requirement in pregnancies complicated by gestational diabetes mellitus (GDM). METHOD:A total of 294 patients with GDM diagnosed by the 100-g/3-h oral glucose tolerance test (OGTT) were studied. The following factors were analyzed: maternal age, nulliparity,...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2009.12.023

    authors: Sapienza AD,Francisco RP,Trindade TC,Zugaib M

    更新日期:2010-04-01 00:00:00

  • Premature loss of muscle mass and function in type 2 diabetes.

    abstract:INTRODUCTION:Muscle mass and function are among the most relevant factors that contribute to an optimal quality of life, and are strong predictors of mortality in the elderly. Loss of lean tissues and deterioration of muscle function have been described as one of the many complications of type 2 diabetes mellitus (DM2)...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2016.04.011

    authors: Guerrero N,Bunout D,Hirsch S,Barrera G,Leiva L,Henríquez S,De la Maza MP

    更新日期:2016-07-01 00:00:00

  • Peripheral vascular reactions to smoking--profound vasoconstriction by atherosclerosis.

    abstract::Analyses of direct effects of smoking on peripheral arteries were done using thermography, blood fluorometry and echography on 97 habitual smoker-diabetics without triopathy. There were found to be four types of thermographic changes following smoking, which varied according to the degree of atherosclerosis of the art...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(98)00084-9

    authors: Fushimi H,Kubo M,Inoue T,Yamada Y,Matsuyama Y,Kameyama M

    更新日期:1998-10-01 00:00:00

  • Nutritional assessment of older adults with diabetes mellitus.

    abstract:AIMS:We aimed to screen the nutritional status of older adults with diabetes mellitus, seeking to outline the needs of this population group considering their socioeconomic status. METHODS:Cross-sectional study of 246 diabetic people aged 65-94 years in Northeastern Brazil. Semi-structured questionnaires were used to ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2019.107819

    authors: Saintrain MVL,Sandrin RLESP,Bezerra CB,Lima AOP,Nobre MA,Braga DRA

    更新日期:2019-09-01 00:00:00

  • Complete remission of diabetic nephropathy in a type 1 diabetic patient with near-nephrotic range proteinuria and reduced renal function.

    abstract::There is scant knowledge on the changes in renal histological findings in type 1 diabetic patients those initially had nephrotic proteinuria and decreased renal function and later had complete remission of diabetic nephropathy by multifactorial treatment (MFT). A 44-year-old Japanese type 1 diabetic woman (duration of...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2008.10.019

    authors: Haraguchi K,Hara S,Ubara Y,Tanaka S,Nukui I,Shimura H,Ohashi K,Kobayashi T

    更新日期:2009-03-01 00:00:00

  • Predicting long-term glycemic control of post-educational type II diabetic patients by evaluating serum 1,5-anhydroglucitol levels.

    abstract::1,5-Anhydroglucitol (1.5-AG) is known to closely reflect diabetic control within several days. The possibility of predicting long-term glycemic control after an educational hospitalization of type II diabetic patients was investigated by examining the relationship between changes in serum 1,5-AG levels after a short-t...

    journal_title:Diabetes research and clinical practice

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0168-8227(96)01340-x

    authors: Sone H,Okuda Y,Yamaoka T,Kawakami Y,Odawara M,Matsushima T,Kawai K,Yamashita K

    更新日期:1996-10-01 00:00:00

  • Leukocyte telomere length correlates with glucose control in adults with recently diagnosed type 2 diabetes.

    abstract:AIMS:We investigated leukocyte relative telomere length (TL) in patients with type 2 diabetes (T2D) diagnosed for no longer than five years and its association with clinical and biochemical variables. METHODS:Peripheral blood leukocyte relative TL was investigated in 108 patients with T2D (87 women, 21 men) and 125 (3...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2017.10.020

    authors: Rosa ECCC,Dos Santos RRC,Fernandes LFA,Neves FAR,Coelho MS,Amato AA

    更新日期:2018-01-01 00:00:00

  • Clinical characteristics of Japanese youth-onset type 2 diabetes with ketonuria.

    abstract::The study analyzed the clinical background and eating habits of Japanese youth-onset type 2 diabetes. Thirty-six patients with type 2 diabetes (22 males, 14 females) with onset in less than 20-year-old were studied. All patients were negative for anti-glutamic acid decarboxylase (GAD) antibody and islet cell antibody....

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2005.03.037

    authors: Matsui J,Tamasawa N,Tanabe J,Kasai N,Murakami H,Matsuki K,Suda T

    更新日期:2005-12-01 00:00:00

  • Beta(3)-adrenergic receptor gene variant is associated with upper body obesity only in obese Japanese-American men but not in women.

    abstract::We investigated gender differences in the relationships between the Trp64Arg variant of the beta(3)-adrenergic receptor (AR) gene in obesity and insulin resistance in nondiabetic subjects. In 476 nondiabetic Japanese-Americans (M/F=204/272), the Trp64Arg variant of the beta(3)-AR gene was examined. The presence or abs...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(01)00284-4

    authors: Kawamura T,Egusa G,Fujikawa R,Okubo M

    更新日期:2001-10-01 00:00:00

  • Increased serum miR-7 is a promising biomarker for type 2 diabetes mellitus and its microvascular complications.

    abstract:AIMS:To investigate the alteration pattern and physiologic state of islet-specific miR-7 in the serum of patients with type 2 diabetes mellitus (T2DM) and T2DM-associated microvascular complications (T2DMC) and to evaluate its clinical significance. METHODS:The levels of serum miR-7 were firstly examined and compared ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2017.06.005

    authors: Wan S,Wang J,Wang J,Wu J,Song J,Zhang CY,Zhang C,Wang C,Wang JJ

    更新日期:2017-08-01 00:00:00

  • An immunopotentiator of beta-1,6;1,3 D-glucan prevents diabetes and insulitis in BB rats.

    abstract::The preventive effect of an immunopotentiator, beta-1,6;1,3 D-glucan, on the development of diabetes and insulitis was studied in BB rats. The intravenous administration of 1 mg kg-1 week-1 of beta-1,6;1,3 D-glucan from the age of 4 weeks decreased the cumulative incidence of diabetes from 43.3% (13/30) to 6.7% (2/30)...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(92)90152-h

    authors: Kida K,Inoue T,Kaino Y,Goto Y,Ikeuchi M,Ito T,Matsuda H,Elliott RB

    更新日期:1992-08-01 00:00:00

  • Serum insulin is a risk marker for coronary heart disease mortality in men but not in women.

    abstract::Serum insulin 1 h post-glucose load is examined in this prospective study of 2971 Caucasoid subjects aged > 20 years in 1966 and followed to 1989. The serum insulin levels as a continuous variable show no significant linear association with coronary heart disease (CHD) deaths in either sex after accounting for age by ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(94)90139-2

    authors: Welborn TA,Knuiman MW,Ward N,Whittall DE

    更新日期:1994-11-01 00:00:00

  • A report on the diagnosis of intermediate hyperglycemia in Korea: A pooled analysis of four community-based cohort studies.

    abstract::Many studies show poor agreement between fasting plasma glucose (FPG)-based and 2-h postchallenge glucose (2-h PG)-based criteria to assess glucose metabolism. We examined the rate of agreement between FPG- and 2-h PG-based criteria in the diagnosis of intermediate hyperglycemia in four representative cohort studies i...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.diabres.2008.01.022

    authors: Oh JY,Lim S,Kim DJ,Kim NH,Kim DJ,Moon SD,Jang HC,Cho YM,Song KH,Ahn CW,Sung YA,Park JY,Shin C,Lee HK,Park KS,Committee of the Korean Diabetes Association on the Diagnosis and Classification of Diabetes Mellitus.

    更新日期:2008-06-01 00:00:00

  • Chronic calcific pancreatitis of the tropics (CCPT): spectrum and correlates of exocrine and endocrine pancreatic dysfunction.

    abstract::The exocrine and endocrine pathophysiology of chronic calcific pancreatitis of the tropics (CCPT) remains elusive. The objective of this study was to evaluate the spectrum and correlates of the exocrine and endocrine pancreatic dysfunction in CCPT. Thirty-seven consecutive patients with a clinico-radiological diagnosi...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(94)01021-q

    authors: Sidhu SS,Shah P,Prasanna BM,Srikanta SS,Tandon RK

    更新日期:1995-02-01 00:00:00

  • Gestational diabetes mellitus among Sub-Saharan African and Surinamese women in the Netherlands.

    abstract:AIM:We assessed the association between ethnicity and the risk of gestational diabetes mellitus (GDM) in the Netherlands. METHODS:A cohort of 7815 women with known GDM status and ethnicity, including women of Sub-Saharan African ethnicity who are currently not identified as high-risk in guidelines. We compared GDM rat...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2020.108367

    authors: Rademaker D,van Schaijik CI,Oostvogels AJJM,van Rijn BB,Evers I,DeVries JH,Agyemang C,Vrijkotte TGM,Painter RC

    更新日期:2020-10-01 00:00:00

  • Microalbuminuria and associated clinical features among Brazilians with insulin dependent diabetes mellitus.

    abstract::With the objective to determine the frequency of microalbuminuria, macroalbuminuria and the associated clinic and metabolic features among insulin dependent diabetes mellitus (IDDM) Brazilian patients attending at a general University Hospital, a total of 50 outpatients, aged 21.9 +/- 7 years with IDDM duration of 6.8...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(97)01368-5

    authors: Gomes MB,Lucchetti MR,Gazzola H,Dimetz T,Gonçalves MF,Neves R,Matos H

    更新日期:1997-03-01 00:00:00

  • Stroke in the patient with diabetes (Part 2) - Prevention and the effects of glucose lowering therapies.

    abstract::There is a higher incidence of stroke in both the type 2 diabetic and the non-diabetic insulin resistant patient which is accompanied by higher morbidity and mortality. Stroke primary prevention can be achieved by controlling atrial fibrillation and hypertension, and the utilization of statins and anticoagulant therap...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,评审

    doi:10.1016/j.diabres.2020.108199

    authors: Bell DSH,Goncalves E

    更新日期:2020-06-01 00:00:00

  • Where is Malaysia in the midst of the Asian epidemic of diabetes mellitus?

    abstract::Population studies all over the world have clearly showed that the prevalence of Type 2 diabetes mellitus (DM) is escalating at phenomenal scale and very likely we are heading towards epidemic proportions. In 1985, the estimated population of diabetic individuals in the world was 30 million but by 1995 this figure soa...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(00)00175-3

    authors: Zaini A

    更新日期:2000-10-01 00:00:00

  • Effects of medicinal food plants on impaired glucose tolerance: A systematic review of randomized controlled trials.

    abstract:BACKGROUND:The objective of this systematic review was to assess available scientific data on the efficacy and safety of medicinal food plants for the treatment of impaired glucose tolerance. METHODS:We included randomized controlled trials (RCTs) with a minimum follow-up period of 6weeks. The diagnosis was determined...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,评审

    doi:10.1016/j.diabres.2017.05.024

    authors: Demmers A,Korthout H,van Etten-Jamaludin FS,Kortekaas F,Maaskant JM

    更新日期:2017-09-01 00:00:00

  • Does working memory training improve dietary self-care in type 2 diabetes mellitus? Results of a double blind randomised controlled trial.

    abstract:AIMS:Controlling food intake despite adequate knowledge remains a struggle for many people with type 2 diabetes. The present study investigated whether working memory training can reduce food intake and improve glycaemic control. It also examined training effects on cognition, food cravings, and dietary self-efficacy a...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.diabres.2018.07.005

    authors: Whitelock V,Nouwen A,Houben K,van den Akker O,Rosenthal M,Higgs S

    更新日期:2018-09-01 00:00:00