Abstract：
:Exposure to PM10 is associated with cardiovascular effects. We evaluated the effects of PM10 on E-Selectin expression and monocytic cell adhesion in human umbilical vein endothelial cells (HUVECs). HUVEC were exposed to PM10 (5-40 microg/cm2) for 6 h, following which surface E-Selectin expression was detected by fluorescence microscopy and flow cytometry. The effects of total particles, particles treated with polymixin-B to block the effects of endotoxin, and both soluble and insoluble fractions of particles, were assessed. Incubation with PM10 lead to a concentration-related increase of E-Selectin expression (>seven-fold increase at 40 microg/cm2). Particles pre-treated with polymixin-B inhibited E-Selectin expression to a level slightly higher than untreated particles. An increase in fluorescence was also observed with the insoluble fraction, while the soluble fraction had no significant effect. HUVEC exposed to PM10 were also evaluated for adhesivity of monocytic cells (U937). PM10 strongly increased the adhesion of U937 cells to HUVEC. In conclusion, PM10 induces endothelial cell activation, evidenced by enhanced E-Selectin expression. This activation is manifested functionally as an increase in monocytic cell adhesion. Insoluble components as well as endotoxins appear to be responsible for this activity.
journal_name
Environ Resjournal_title
Environmental researchauthors
Alfaro-Moreno E,López-Marure R,Montiel-Dávalos A,Symonds P,Osornio-Vargas AR,Rosas I,Clifford Murray Jdoi
10.1016/j.envres.2006.05.004subject
Has Abstractpub_date
2007-02-01 00:00:00pages
221-8issue
2eissn
0013-9351issn
1096-0953pii
S0013-9351(06)00108-3journal_volume
103pub_type
杂志文章abstract：:The relationship of inorganic arsenic exposure through drinking water and total urinary arsenic excretion in a nonoccupationally exposed population was evaluated in a cross-sectional study in three mayor cities of Chile (Antofagasta, Santiago, and Temuco). A total of 756 individuals in three population strata (elderly...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2005.02.007
更新日期：2005-06-01 00:00:00
abstract：OBJECTIVES:Our objective was to examine the relationship between residential proximity to agricultural fumigant use and neurodevelopment in 7-year old children. METHODS:Participants were living in the agricultural Salinas Valley, California and enrolled in the Center for the Health Assessment of Mothers and Children O...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.06.036
更新日期：2017-10-01 00:00:00
abstract：:The growing human population concentrated in urban areas lead to the increase of road traffic and artificial areas, consequently enhancing air pollution and urban heat island effects, among others. These environmental changes affect citizen's health, causing a high number of premature deaths, with considerable social ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.10.006
更新日期：2018-01-01 00:00:00
abstract：:Exposure to inorganic fluoride (F) has been implicated in cardiovascular and kidney dysfunction mainly in adult populations. However, limited epidemiological information from susceptible populations, such as children, is available. In this study we evaluated the relationship of F exposure with some vascular and kidney...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2018.10.028
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Long-term exposure to ambient fine particulate matter (≤ 2.5 μg/m3 in aerodynamic diameter; PM2.5) is significantly associated with increased risk of premature mortality. Our goal was to provide an updated meta-analysis of all-cause and cause-specific mortality associated with exposure to PM2.5 and to better...
journal_title：Environmental research
pub_type： 杂志文章,meta分析
doi：10.1016/j.envres.2018.06.021
更新日期：2018-10-01 00:00:00
abstract：:Large areas of mainland China have been suffering frequently from heavy haze pollution during the past years, which feature high concentrations of fine particulate matter (PM2.5, particulate matters with aerodynamic diameters less than 2.5 μm) and low visibility. Moreover, these areas manifested strong regional comple...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109368
更新日期：2020-05-01 00:00:00
abstract：:Adult male inbred Wistar rats were given a subtoxic dose of cadmium (25 ppm) orally for 4 weeks prior to and during immunization with sheep erythrocytes (E). The control group received tap water during the experimental period. No difference in the antibody response to E was found between the two groups. Mononuclear pe...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(83)90019-1
更新日期：1983-08-01 00:00:00
abstract：:Paraquat is known to produce hyperglycemia in rodents, although the mechanisms responsible for the hyperglycemic effect of paraquat are not clearly understood. In this study we report the effects of paraquat (25 mg/kg iv) on plasma glucose, cortisol, catecholamines, and insulin in dogs. Paraquat caused a significant i...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(83)90169-x
更新日期：1983-02-01 00:00:00
abstract：:The human exposome affects child development and health later in life, but its personal external levels, variability, and correlations are largely unknown. We characterized the personal external exposome of pregnant women and children in eight European cities. Panel studies included 167 pregnant women and 183 children...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.04.015
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND:Prenatal exposure to perfluoralkyl substances (PFASs) has been reported to be associated with immunosuppression in early childhood, but with contradictory findings related to atopic and lung diseases. AIM:We aimed to determine if prenatal exposure to PFASs is associated with asthma or other allergic disease...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.10.012
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Both traffic-related noise and air pollution have been associated with cardiovascular disease (CVD). Spatial correlations between these environmental stressors may entail mutual confounding in epidemiological studies investigating their long-term effects. Few studies have investigated their correlation - non...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2010.10.013
更新日期：2011-01-01 00:00:00
abstract：:Increasing the number of applications of rare earth elements (REEs) has led to increased release of these metals into the environment. Removal of REEs from e-wastes is very important considering the increasing demand for these elements, the limited resource availability of them as well as the significant environmental...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110171
更新日期：2020-12-01 00:00:00
abstract：:The TiO2 based photocatalyst has great potential for the disinfection/inactivation of harmful pathogens (such as E.coli in aqueous media) along with its well-known usefulness on various chemical pollutants. The disinfection property of TiO2 is primarily attributed to surface generation of reactive oxygen species (ROS)...
journal_title：Environmental research
pub_type： 杂志文章,评审
doi：10.1016/j.envres.2017.01.018
更新日期：2017-04-01 00:00:00
abstract：:The Amazon rainforest has sustained human existence for more than 10,000 years. Part of this has been the way that the forest controls regional climate including precipitation important for the ecosystem as well as agroforestry and farming. In addition, the Amazon also affects the global weather systems, so cutting do...
journal_title：Environmental research
pub_type： 杂志文章,评审
doi：10.1016/j.envres.2019.108887
更新日期：2020-02-01 00:00:00
abstract：:The effects of methylmercury administration on adenosine 3',5'-cyclic monophosphate (cAMP)-dependent protein kinase (protein kinase A) and protein kinase C were investigated by determining their second messenger bindings ([3H]cAMP binding for protein kinase A and [3H]PDBu for protein kinase C) and enzymatic activities...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1993.1146
更新日期：1993-11-01 00:00:00
abstract：:Recent data show that arsenic may play a role in obesity-related diseases. However, urinary arsenic studies report an inverse association between arsenic level and body mass index (BMI). We explored whether toenail arsenic, a long-term exposure measure, was associated with BMI in 74 welders with known arsenic exposure...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2014.03.010
更新日期：2014-05-01 00:00:00
abstract：:The toxicity of isopropyl alcohol (IPA) on the nasal mucosa in the guinea pig was experimentally studied, with special reference to the recovery process of the organ. The results showed that 400 ppm of IPA has an acute effect on the nasal mucosa and the recovery from such degeneration can occur in 2 weeks. When functi...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(88)80056-2
更新日期：1988-06-01 00:00:00
abstract：:The burden of organophosphate (OP) pesticides in pregnant women from Tarragona (n = 157), a Mediterranean area of intense agricultural activity, has been assessed from the study of hydroxylated organic metabolites in urine samples in the three trimesters of pregnancy. 2-Diethylamino-6-methylpyrimidin-4-ol (DEAMPY), a ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.109003
更新日期：2020-03-01 00:00:00
abstract：:Trees are considered producers of allergenic pollen. The aims of this work were to characterize the aerobiology of the Platanus, Acer, Salix, Quercus, Betula and Populus pollen, linking it with monthly emergency hospital admissions and to identify the different reactivity levels in sensitized patients. This informatio...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2008.11.008
更新日期：2009-04-01 00:00:00
abstract：:Heat waves are anticipated to worsen with climate change. India, an understudied area with >15% of the world's population, commonly experiences temperature extremes and already resembles potential future climates of more temperate regions. Registry data from local municipal corporations and government offices were col...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.108546
更新日期：2019-09-01 00:00:00
abstract：:Calcium and phosphorus were mainly responsible for reducing the gastrointestinal absorption of lead in human subjects. The effect of calcium was greater than phosphorus, and their combined effect was more than additive. Increasing weights of calcium and phosphorus progressively reduced lead absorption. The relationshi...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(83)90179-2
更新日期：1983-02-01 00:00:00
abstract：:An attempt has been made to study the biochemical properties of lung alkaline phosphatase so that it may serve as a model for measuring the toxicity of air pollutants, especially metals. Lung was shown to be a better source of this enzyme in comparison to other organs in rats. The optimum pH, metal requirements, subst...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(87)80053-1
更新日期：1987-06-01 00:00:00
abstract：:Ambient air pollution is the leading environmental risk factor for disease globally. Air pollutants can increase the risk of some respiratory infections, but their effects on tuberculosis (TB) are unclear. In this systematic literature review, we aimed to assess epidemiological studies on the association between outdo...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2018.12.011
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:Summer temperatures are expected to increase and heat waves will occur more frequently, be longer, and be more intense as a result of global warming. A growing body of evidence indicates that increasing temperature and heatwaves are associated with excess mortality and therefore global heating may become a m...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109848
更新日期：2020-09-01 00:00:00
abstract：:The cytotoxic activity of the DQ-12 standard dust on the external structure of peritoneal macrophages, after intraperitoneal introduction, was investigated, vs nontreated macrophages, and kept in in vitro cultures for 3, 6, and 24 hr. The alterations related to the external structure were investigated by scanning elec...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(83)90002-6
更新日期：1983-08-01 00:00:00
abstract：:The influence of anthropogenic pollution, particularly with polycyclic aromatic hydrocarbons (PAHs) on soil toxicity and spread of antibiotic resistance genes (ARGs) is extremely important nowadays. We studied 20 soil samples from a technogenically polluted site, municipal solid wastes (MSW) landfills, and rural settl...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2021.110715
更新日期：2021-01-11 00:00:00
abstract：:The spread of pharmaceutically active chemicals (PACs), such as antibiotics and estrogenic hormones from animal manures can pose threats to the ecologic environment. In this work, animal manure samples were collected from 71 concentrated animal feedlots in Northern China and investigated for 24 antibiotics and 4 estro...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.110463
更新日期：2020-11-13 00:00:00
abstract：:Radon (222Rn) concentrations in 26 ground water wells of two distinct lithologies in the Piedmont of Virginia were measured to assess variation in ground water radon concentrations (GWRC), to evaluate differences in concentrations related to well characteristics, lithology, and spatial distributions, and to assess the...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2006.02.002
更新日期：2006-07-01 00:00:00
abstract：:Chlorinated solvents (CS)-contaminated groundwater poses serious risks to the environment and public health. Microorganisms play a vital role in efficient remediation of CS. In this study, the microbial community (bacterial and archaeal) composition of three CS-contaminated groundwater wells located at an abandoned ch...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109457
更新日期：2020-06-01 00:00:00
abstract：:Fish consumption from the Great Lakes and the St. Lawrence River has been decreasing over the last years due to advisories and increased awareness of the presence of several contaminants. Methylmercury (MeHg), a well-established neurotoxicant even at low levels of exposure, bioaccumulates to differing degrees in vario...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2003.12.007
更新日期：2004-07-01 00:00:00
