Diagnostic value of serum gamma-glutamyl transpeptidase activity in liver diseases in children.

abstract：:We evaluated nutritional status, pulmonary impairment, nutritional intake, and fat absorption in 73 cystic fibrosis (CF) patients to identify the primary factor(s) influencing growth. In general, the growth pattern in our patients was satisfactory since 60/73 were not underweight. When caloric intake is greater than o...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Costantini D,Padoan R,Curcio L,Giunta A

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:The newborn colon is devoid of microflora, in that bacterial colonization is established after birth. Short chain fatty acids, products of bacterial fermentation, are the major energy source for colonocytes. Because it is not known whether colonocytes in the newborn can metabolize butyrate, this was examined...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Krishnan S,Ramakrishna BS

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVES:Infant colic (IC), with an estimated prevalence of 5% to 25%, has a high impact on health care costs. Furthermore, reported negative sequelae are disturbed parent-infant interaction, increased susceptibility to abdominal pain, and even child abuse. Its etiology remains unknown, leading to a wide variety in i...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Steutel NF,Benninga MA,Langendam MW,de Kruijff I,Tabbers MM

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:Midgut volvulus with malrotation is typical in newborns. We present our experience to emphasize the importance of suspecting midgut volvulus as a cause of abdominal pain also beyond infancy, particularly in relation to malrotation, and the relevance of ultrasonographic (US) signs in its diagnosis. METHODS:A...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Esposito F,Vitale V,Noviello D,Di Serafino M,Vallone G,Salvatore M,Oresta P

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:To evaluate the effect of a therapeutic regimen of 7 days versus 14 days on the clinical manifestations of Helicobacter pylori gastritis in children. METHODS:Ninety children (age 2-19 years) who had abdominal pain and/or recurrent vomiting were determined to have H. pylori gastritis by endoscopy, histology,...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Shamaly H,Berkowitz D,Rosenthal E,Naveh Y

更新日期：2000-02-01 00:00:00

abstract：:A 24-month-old female child experienced watery diarrhea, growth failure, and abdominal pain from age 3 months. Hypergastrinemia, hypochlorhydria, and fundic gastritis were documented. A secretin stimulation test was normal but protein meal stimulation revealed an abnormal serum gastrin response. Antral biopsies reveal...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Euler AR,Lechago J,Byrne W,France GL

更新日期：1984-03-01 00:00:00

abstract：OBJECTIVES:Data on the outcomes of children with perianal Crohn disease (pCD) are limited, although its presence is often used for justifying early use of biologics. We aimed to assess whether pCD in children is associated with more severe outcomes as found in adults. METHODS:Data were extracted from the ImageKids dat...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Assa A,Amitai M,Greer ML,Castro DA,Kuint RC,Martínez-León M,Herman-Sucharska I,Coppenrath E,Anupindi S,Towbin A,Moote D,Konen O,Pratt LT,Griffiths A,Turner D,ImageKids Study Group.

更新日期：2017-09-01 00:00:00

abstract：:A prolonged but transient neonatal jaundice due to unconjugated hyperbilirubinemia was observed in two unrelated babies who were siblings of patients with Crigler--Najjar disease (Arias type I). The bilirubin-UDP-glucuronyl transferase activity measured in the liver of both patients, at the age of 6 and 7 months, resp...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Odièvre M,Luzeau R,Alagille D

更新日期：1982-01-01 00:00:00

abstract：:It appears that neonates, especially those with very low birthweights, may be at especially high risk of developing cholestasis associated with total parenteral nutrition (TPN). Within 2 weeks of starting intravenous alimentation, it would appear highly desirable to be able to start at least small enteral feedings to ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Merritt RJ

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Earlier studies report the excessive faecal excretions of bile acids and dietary residues in cystic fibrosis (CF). However, few of these investigated large groups of patients using modern pancreatin preparations and little data exists reporting carbohydrate excretion. We therefore aimed to characterise the g...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Walters MP,Littlewood JM

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Hepatic lesions have been described in Alagille syndrome (ALGS) in isolated case reports, and most of these have been reported to be hepatocellular carcinoma. OBJECTIVES:The aim of the present study was to determine the frequency, imaging, and histopathologic characteristics of hepatic lesions in children w...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Alhammad A,Kamath BM,Chami R,Ng VL,Chavhan GB

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVES:Infectious diarrhea, a leading cause of morbidity and deaths, is less prevalent in breastfed infants compared with infants fed infant formula. The dominant human milk oligosaccharide (HMO), α-1,2-fucosyllactose (2'-FL), has structural homology to bacterial adhesion sites in the intestine and may in part expl...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Cilieborg MS,Sangild PT,Jensen ML,Østergaard MV,Christensen L,Rasmussen SO,Mørbak AL,Jørgensen CB,Bering SB

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to describe the prevalence of childhood constipation, stool characteristics, and their relationship with toilet training and age of introduction of cow's milk. METHODS:A total of 4231 children born in 2004, from a birth cohort study, were assessed at 12, 24, and 48 months of...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Mota DM,Barros AJ,Santos I,Matijasevich A

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Shwachman's syndrome is the second most common cause of inherited/congenital pancreatic insufficiency after cystic fibrosis. The main associated features are usually cyclic neutropenia, metaphyseal dysostosis, and growth retardation. Other organs or functions may be involved in this syndrome, showing a wide ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Cipolli M,D'Orazio C,Delmarco A,Marchesini C,Miano A,Mastella G

更新日期：1999-09-01 00:00:00

abstract：:Pediatric gastrointestinal endoscopy has been established as safe and effective for diagnosis and management of many pediatric gastrointestinal diseases. Nevertheless, certain patient and procedure factors should be recognized that increase the risk of intra- and/or postprocedural adverse events (AEs). AEs associated ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Lightdale JR,Liu QY,Sahn B,Troendle DM,Thomson M,Fishman DS,NASPGHAN Endoscopy and Procedures Committee.

更新日期：2019-04-01 00:00:00

abstract：:Hepatitis C virus (HCV) is an RNA virus that affects >180 million individuals worldwide with a high propensity for chronic infection. Children with HCV infection differ from adults in several ways including some modes of transmission, rates of clearance, progression of fibrosis, and the duration of potential chronic i...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Mack CL,Gonzalez-Peralta RP,Gupta N,Leung D,Narkewicz MR,Roberts EA,Rosenthal P,Schwarz KB,North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:Polyethylene glycol (PEG) is a frequently used laxative agent. It is unknown, however, whether PEG affects the absorptive capacity of the intestine. Reduced lipid (dietary fat and cholesterol) absorption induced by long-term PEG treatment could negatively affect growth in children. We tested whether PEG acce...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： van der Wulp MY,Cuperus FJ,Stellaard F,van Dijk TH,Dekker J,Rings EH,Groen AK,Verkade HJ

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:Low γ-glutamyl transpeptidase (GGT) level is an important marker for progressive familial intrahepatic cholestasis, yet the cutoff level and clinical application is not well defined. This study aimed to evaluate the role of GGT as a screening marker among diverse etiologies of infantile cholestasis. METHODS...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Lu FT,Wu JF,Hsu HY,Ni YH,Chang MH,Chao CI,Chen HL

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND AIM:Patients with cystic fibrosis (CF) have low levels of n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) in plasma or red blood cells (RBC), as also seen in other chronic and acute liver diseases. The differences may be more pronounced in CF transmembrane conductance regulator protein (CFTR)-reg...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Jørgensen MH,Ott P,Michaelsen KF,Porsgaard T,Jensen F,Lanng S

更新日期：2012-07-01 00:00:00

abstract：:In a double-blind, placebo-controlled, randomized study we measured the effect of 1 mg/kg intravenous metoclopramide on the gastric emptying of a 15 ml/kg 5% glucose meal, using a phenol red dye dilution technique. In a group of nine infants referred for multiple daily episodes of regurgitation, metoclopramide doubled...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hyman PE,Abrams CE,Dubois A

更新日期：1988-03-01 00:00:00

abstract：:Five children between the ages of 10 and 17 years with chronic inflammatory bowel disease with involvement of colon had intolerance to sulfasalazine, and desensitization trials had failed in them. In addition, they were steroid dependent. Therefore treatment was tried with an oral 5-aminosalicylic acid (5-ASA) prepara...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Tolia V,Massoud N,Klotz U

更新日期：1989-04-01 00:00:00

abstract：OBJECTIVES:Congenital hepatic fibrosis (CHF) is an important cause of morbidity and mortality in patients with autosomal recessive polycystic kidney disease (ARPKD). The pathogenesis of CHF remains undefined. Several recent studies suggest that the renin-angiotensin system (RAS) is an important mediator of progressive ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Goto M,Hoxha N,Osman R,Wen J,Wells RG,Dell KM

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To conduct a comprehensive study of postendoscopic adverse events (AEs) in children, categorizing them by the level of intervention required. BACKGROUND:Previous studies of endoscopic AE in children have focused on intraprocedural and short-term outcomes, such as bleeding, perforation, and infection, and may...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kramer RE,Narkewicz MR

更新日期：2016-06-01 00:00:00

abstract：:This cross-sectional study evaluates the relations between the water load test in childhood functional gastrointestinal disorders with food intake and nutritional status. Patients with functional dyspepsia required a lower maximum water intake to produce fullness (n = 11, median = 380 mL) than patients with irritable ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ozaki RK,Soares AC,Speridião Pda G,de Morais MB

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:X-linked inhibitor of apoptosis (xIAP) deficiency is a primary immune deficiency disorder associated with hemophagocytic lymphohistiocytosis. About 17% of xIAP-deficient patients present with very early onset severe colitis with high mortality. We hypothesized that xIAP deficiency leads to defective generatio...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Gurram B,Hammelev E,Syverson G,Haribhai D,Yan K,Simpson P,Salzman N,Verbsky JW

更新日期：2016-08-01 00:00:00

abstract：:Alkaline phosphatase (AP) activity is an accepted marker of epithelial cell differentiation and integrity in intestinal mucosal explant systems. In experiments involving AP it is usually expressed as activity per unit protein in tissue culture. It has been previously demonstrated that during organ culture a considerab...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ashkenazi A,Idar D,Maimon M,Hegesh E,Frank E,Hahn T,Wolman Y,Levin S

更新日期：1984-03-01 00:00:00

abstract：OBJECTIVES:This study was performed to compare the effects of oral midazolam and oral diazepam, administered with intravenous (IV) meperidine, on pre-procedural, procedural, and post-procedural sedation and recovery in children undergoing diagnostic upper endoscopy. The costs of pre-procedure sedation were compared for...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Martinez JL,Sutters KA,Waite S,Davis J,Medina E,Montano N,Merzel D,Marquez C

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Total esophagogastric dissociation (TED) was first described in 1997 by Bianchi as a new surgical procedure to treat severe gastroesophageal reflux disease (GERD) in children with neurological impairment. Recently, TED has been proposed in other conditions, such as esophageal atresia, esotracheal cleft, or c...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Madre C,Serhal L,Michaud L,Bonnevalle M,de Lagausie P,Gottrand F,Bonnard A,Hugot JP

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:The World Health Organization (WHO) recommends exclusive breast-feeding during the first 4 to 6 months of life, but limited information is available regarding the growth performance of infants fed according to the recommendation. The present study used data from the Euro-Growth study to determine the growth ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Haschke F,van't Hof MA

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Animal and human studies have suggested that trans fatty acids might alter some physiological functions and adversely affect the growth and essential fatty acid balance of infants. In this context it is important to know the fatty acid composition, including the levels of trans isomers of oleic, linoleic and...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ratnayake WM,Chardigny JM,Wolff RL,Bayard CC,Sébédio JL,Martine L

更新日期：1997-10-01 00:00:00