Expression of MCP-1 in the hippocampus of SHRSP with ischemia-related delayed neuronal death.

abstract：:This study explores primarily the role of the activity of monoamine oxidase B (MAOB) in the regulation of glutamic acid decarboxylase(67) (GAD(67)) expression in distinct layers of main olfactory bulb (OlfB), which links the limbic system. Moreover, the response of GAD(67) was investigated to amphetamine perturbation ...

journal_title：Cellular and molecular neurobiology

authors： Yin HS,Chen K,Shih JC,Tien TW

更新日期：2010-05-01 00:00:00

abstract：:Alpha-synuclein (alpha-SYN) is one of the major components of intracellular fibrillary aggregates in the brains of a subset of neurodegenerative disorders. Although alpha-SYN expression has been found in developing mouse brain, a detailed distribution during mouse-embryonic development has not been made. Here we descr...

journal_title：Cellular and molecular neurobiology

authors： Zhong SC,Luo X,Chen XS,Cai QY,Liu J,Chen XH,Yao ZX

更新日期：2010-04-01 00:00:00

abstract：:Overexpression of suppressor of cytokine signalling 2 (SOCS2) has been shown to promote hippocampal neurogenesis in vivo and promote neurite outgrowth of neurons in vitro. In the adult mouse brain, SOCS2 is most highly expressed in the hippocampal CA3 region and at lower levels in the dentate gyrus, an expression patt...

journal_title：Cellular and molecular neurobiology

authors： Basrai HS,Turbic A,Christie KJ,Turnley AM

更新日期：2017-07-01 00:00:00

abstract：:Spinal cord injury (SCI) remains a formidable challenge in the clinic. In the current study, we examined the effects of the TLX gene on the proliferation and neuronal differentiation of dermal multipotent stem cells (DMSCs) in vitro and the potential of these cells to improve SCI in rats in vivo. DMSCs were stably tra...

journal_title：Cellular and molecular neurobiology

authors： Wang T,Ren X,Xiong J,Zhang L,Qu J,Xu W

更新日期：2011-04-01 00:00:00

abstract：:1. The HCS2 (Helix command specific 2) gene expressed in giant command neurons for withdrawal behavior of the terrestrial snail Helix lucorum encodes a unique hybrid precursor protein that contains a Ca-binding (EF-hand motif) protein and four small peptides (CNP1-CNP4) with similar Tyr-Pro-Arg-X aminoacid sequence at...

journal_title：Cellular and molecular neurobiology

authors： Ivanova JL,Leonova OG,Popenko VI,Ierusalimsky VN,Korshunova TA,Boguslavsky DV,Malyshev AY,Balaban PM,Belyavsky AV

更新日期：2006-03-01 00:00:00

abstract：:Alzheimer disease is a complex neurodegenerative disorder. It is the common form of dementia in elderly people. The etiology of this disease is multifactorial, pathologically it is accompanied with accumulation of amyloid beta and neurofibrillary tangles. Accumulation of amyloid beta and mitochondrial dysfunction lead...

journal_title：Cellular and molecular neurobiology

authors： Sajjad N,Wani A,Sharma A,Ali R,Hassan S,Hamid R,Habib H,Ganai BA

更新日期：2019-04-01 00:00:00

abstract：:The effects of the divalent cations Ca and Mg on the properties of ACh-activated channels at the frog neuromuscular junction were studied using a two-microelectrode voltage clamp. The divalent cation concentration was varied from 2 to 40 mM in solutions containing 50% normal Na. The reversal potential was determined b...

journal_title：Cellular and molecular neurobiology

authors： Lewis CA

更新日期：1984-09-01 00:00:00

abstract：:The aim of this review was to give a general aspect of the sensorial function of the striatum related to pain modulation, which was intensively studied in our laboratory. We analyse the effect of electrical and chemical stimulation of the striatum on the orofacial pain, especially that produced by tooth pulp stimulati...

journal_title：Cellular and molecular neurobiology

authors： Barceló AC,Filippini B,Pazo JH

更新日期：2012-01-01 00:00:00

abstract：:Acute encephalopathy is a generic term for acute brain dysfunction occurring after infection. Acute encephalopathy induced by influenza virus results in high mortality, and most cases of influenza-associated encephalopathy (IAE) result in brain edema. Administration of diclofenac sodium (DCF), a non-steroidal anti-inf...

journal_title：Cellular and molecular neurobiology

authors： Asai H,Kakita H,Aoyama M,Nagaya Y,Saitoh S,Asai K

更新日期：2013-04-01 00:00:00

abstract：:We have screened new drugs with a view to developing effective drugs against glutamate-induced excitotoxicity. In the present work, we show effects of a new drug, 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride against glutamate-induced excitotoxicity in primary rat glial cultures. Pretreatment of glial cells...

journal_title：Cellular and molecular neurobiology

authors： Kim EA,Hahn HG,Kim KS,Kim TU,Choi SY,Cho SW

更新日期：2010-07-01 00:00:00

abstract：:Organotellurium compounds have been synthesized since 1840, but pharmacological and toxicological studies about them are still incipient. Therefore, the objective of this study was to verify the effect of acute administration of the organochalcogen 3-butyl-1-phenyl-2-(phenyltelluro)oct-en-1-one on some parameters of o...

journal_title：Cellular and molecular neurobiology

authors： Funchal C,Carvalho CA,Gemelli T,Centeno AS,Guerra RB,Salvador M,Dani C,Coitinho A,Gomez R

更新日期：2010-10-01 00:00:00

abstract：:We demonstrated synchronous oscillation of intracellular Ca2+ in cultured-mouse mid-brain neurons. This synchronous oscillation was thought to result from spontaneous and synchronous neural bursts in a synaptic neural network. We also examined the role of endogenous dopamine in neural networks showing synchronous osci...

journal_title：Cellular and molecular neurobiology

authors： Yasumoto F,Negishi T,Ishii Y,Kyuwa S,Kuroda Y,Yoshikawa Y

更新日期：2004-02-01 00:00:00

abstract：:In rats, variations in the levels of neuromodulatory molecules and in the expression of their receptors are observed during pregnancy and postpartum. These changes may contribute to the development and management of maternal behavior. The frequency of licking the pups is used to evaluate maternal care, having mothers ...

journal_title：Cellular and molecular neurobiology

authors： de Moura AC,da Silva IR,Reinaldo G,Dani C,Elsner VR,Giovenardi M

更新日期：2016-10-01 00:00:00

abstract：:1. 125I-Endothelin (ET)-1 binding to the rat anterior pituitary gland was saturable and single, with a Kd of 71 pM and a Bmax of 120 fmol/mg. 2. When 1.0 microM BQ-123 (ETA antagonist) was added to the incubation buffer, the binding parameters were 8.3 pM and 8.0 fmol/mg, whereas 10 nM sarafotoxin S6c (ETB agonist) ex...

journal_title：Cellular and molecular neurobiology

authors： Himeno A,Shigematsu K,Taguchi T,Niwa M

更新日期：1998-08-01 00:00:00

abstract：:Shengmai (SM) formula, a classical traditional Chinese medicine formula, is composed of Panax ginseng (Pg), Ophiopogon japonicus (Oj), and Schisandra Chinesis (Sc). SM has been clinically used to treat heart failure and ischemic heart disease. Although SM formula has been reported to be potential for fighting against ...

journal_title：Cellular and molecular neurobiology

authors： Zhang W,Zhi D,Ren H,Wang D,Wang X,Zhang Z,Fei D,Zhu H,Li H

更新日期：2016-11-01 00:00:00

abstract：:1. RNA interference (RNAi) is a multicomponent machinery that operates in a sequence-specific manner to repress the expression of genes in most eukaryotic cells. 2. Here we wanted to investigate in a murine neuroblastoma cell line (NBP2) (a) if replacement of the loop of the short hairpin RNA (shRNA) with a hammerhead...

journal_title：Cellular and molecular neurobiology

authors： Nahreini P,Hanson AJ,Andreatta CP,Koustas WT,Prasad KN

更新日期：2004-12-01 00:00:00

abstract：:Depression is a major psychiatric disorder affecting nearly 21% of the world population and imposes a substantial health burden on society. Although significant progress has been made in depression research, the common molecular mechanism of antidepressants is still far from clearly understood. The neuroprotective eff...

journal_title：Cellular and molecular neurobiology

authors： Zheng M,Liu C,Pan F,Shi D,Ma F,Zhang Y,Zhang Y

更新日期：2011-04-01 00:00:00

abstract：:1. Alpha-synuclein is known to play an important role in the pathogenesis of Parkinson's disease (PD). The pathogenicity of alpha-synuclein is related to its ability to form intraneuronal inclusions. The inclusions, which are found in brains of patients with PD and diffuse Lewy body disease consist partially of C-term...

journal_title：Cellular and molecular neurobiology

authors： Zach S,Bueler H,Hengerer B,Gillardon F

更新日期：2007-06-01 00:00:00

abstract：:Mental retardation, which occurs in phenylketonuric patients, is associated with increased levels of phenylalanine, increased oxidative stress, and an imbalance of amino acids in the brain. Recent studies have shown that oxidative stress plays a role in the pathogenesis of phenylketonuria. In this work, we aimed to co...

journal_title：Cellular and molecular neurobiology

authors： Kumru B,Kaplan DS,Oztürk Hismi B,Celik H

更新日期：2018-07-01 00:00:00

abstract：:The original version of this article unfortunately contained a typo in co-author name. ...

journal_title：Cellular and molecular neurobiology

authors： Narayan A,Hunkele A,Xu J,Bassoni DL,Pasternak GW,Pan YX

更新日期：2020-10-31 00:00:00

abstract：:Cannabinoid (CB) ligands have demonstrated neuroprotective properties. In this study we compared the effects of a diverse set of CB ligands against β amyloid-mediated neuronal toxicity and activated microglial-conditioned media-based neurotoxicity in vitro, and compared this with a capacity to directly alter β amyloid...

journal_title：Cellular and molecular neurobiology

authors： Janefjord E,Mååg JL,Harvey BS,Smid SD

更新日期：2014-01-01 00:00:00

abstract：:As a novel cell cycle inhibitor, PHB2 controls the G1/S transition in cycling cells in a complex manner. Its aberrant expression is closely related to cell carcinogenesis. While its expression and role in peripheral nervous system lesion and repair were still unknown. Here, we performed an acute sciatic nerve crush (S...

journal_title：Cellular and molecular neurobiology

authors： Long L,Huang Y,Wu H,Luan W,Zhang Q,Wen H,Ding T,Wang Y

更新日期：2013-07-01 00:00:00

abstract：:In spinal cord synaptosomes, the spider toxin PhTx3-4 inhibited capsaicin-stimulated release of glutamate in both calcium-dependent and -independent manners. In contrast, the conus toxins, ω-conotoxin MVIIA and xconotoxin MVIIC, only inhibited calcium-dependent glutamate release. PhTx3-4, but not ω-conotoxin MVIIA or ...

journal_title：Cellular and molecular neurobiology

authors： Gonçaves JM,Ferreira J,Prado MA,Cordeiro MN,Richardson M,Pinheiro AC,Silva MA,Junior CJ,Souza AH,Gomez MV

更新日期：2011-03-01 00:00:00

abstract：:Podoplanin (PDPN) is a mucin-type transmembrane sialoglycoprotein expressed in multiple tissues in adult animals, including the brain, lungs, kidney, and lymphoid organs. Studies of this molecule have demonstrated its great importance in tumor metastasis, platelet aggregation, and lymphatic vessel formation. However, ...

journal_title：Cellular and molecular neurobiology

authors： Song Y,Shen J,Lin Y,Shen J,Wu X,Yan Y,Zhou L,Zhang H,Zhou Y,Cao M,Liu Y

更新日期：2014-08-01 00:00:00

abstract：:We provide a comprehensive review of the available evidence on the pathophysiological implications of genetic variants in the human trace amine-associated receptor (TAAR) superfamily. Genes coding for trace amine-associated receptors (taars) represent a multigene family of G-protein-coupled receptors, clustered to a s...

journal_title：Cellular and molecular neurobiology

authors： Rutigliano G,Zucchi R

更新日期：2020-03-01 00:00:00

abstract：:One of the plausible ways to prevent the reactive oxygen species (ROS)-mediated cellular injury is dietary or pharmaceutical augmentation of endogenous antioxidant defense capacity. In this study, we investigated the neuroprotective effect of fucoidan on H(2)O(2)-induced apoptosis in PC12 cells and the possible signal...

journal_title：Cellular and molecular neurobiology

authors： Gao Y,Dong C,Yin J,Shen J,Tian J,Li C

更新日期：2012-05-01 00:00:00

abstract：:Endothelins have been implicated in the regulation of cell proliferation, differentiation, and apoptosis, but the mechanisms of these complex events are not yet fully understood. Although the nuclear factor-kappaB (NF-kappaB) was shown to play a prominent role in the above processes, its participation in endothelin re...

journal_title：Cellular and molecular neurobiology

authors： Mangelus M,Galron R,Naor Z,Sokolovsky M

更新日期：2001-12-01 00:00:00

abstract：:The allelic variant of apolipoprotein (Apo) E4 is a known risk factor for the development of most common late onset form of Alzheimer's disease (AD). As aging is associated with reduced circulating level of gonadal steroid hormones, hormone replacement therapies have been used for the possible treatment of AD. Both es...

journal_title：Cellular and molecular neurobiology

authors： Singh S,Thakur MK

更新日期：2011-04-01 00:00:00

abstract：:Membrane responses to cyclic adenosine monophosphate (cAMP) injections have been studied by means of voltage clamp, Ca-indicator dye, and ion substitution techniques in identified neurons from the abdominal ganglion of Limax maximus. The ventral abdominal giant cell (AGC) displayed a response consisting of a decrease ...

journal_title：Cellular and molecular neurobiology

authors： Hockberger P,Connor JA

更新日期：1984-12-01 00:00:00

abstract：:Glioblastoma is the most malignant primary brain tumor and is very resistant to treatment; hence, it has a poor prognosis. Neurotensin receptor type 1 (NTSR1) plays a key role in cancer malignancy and has potential therapeutic applications. However, the presence and function of neurotensin (NTS) receptors in glioblast...

journal_title：Cellular and molecular neurobiology

authors： Ayala-Sarmiento AE,Martinez-Fong D,Segovia J

更新日期：2015-08-01 00:00:00