Abstract：
:Optical coherence tomography (OCT) uses retroreflected light to provide micrometer-resolution, cross-sectional scans of biological tissues. OCT's first application was in ophthalmic imaging where it has proven particularly useful in diagnosing, monitoring, and studying glaucoma. Diagnosing glaucoma is difficult and it often goes undetected until significant damage to the subject's visual field has occurred. As glaucoma progresses, neural tissue dies, the nerve fiber layer thins, and the cup-to-disk ratio increases. Unfortunately, most current measurement techniques are subjective and inherently unreliable, making it difficult to monitor small changes in the nervehead geometry. To our knowledge, this paper presents the first published results on optic nervehead segmentation and geometric characterization from OCT data. We develop complete, autonomous algorithms based on a parabolic model of cup geometry and an extension of the Markov model introduced by Koozekanani, et al. to segment the retinal-nervehead surface, identify the choroid-nervehead boundary, and identify the extent of the optic cup. We present thorough experimental results from both normal and pathological eyes, and compare our results against those of an experienced, expert ophthalmologist, reporting a correlation coefficient for cup diameter above 0.8 and above 0.9 for the disk diameter.
journal_name
IEEE Trans Med Imagingjournal_title
IEEE transactions on medical imagingauthors
Boyer KL,Herzog A,Roberts Cdoi
10.1109/TMI.2006.871417subject
Has Abstractpub_date
2006-05-01 00:00:00pages
553-70issue
5eissn
0278-0062issn
1558-254Xjournal_volume
25pub_type
杂志文章abstract：:Deep tissue injuries are subcutaneous regions of tissue breakdown associated with excessive mechanical pressure for extended period of time. These wounds are currently clinically undetectable in their early stages and result in severe burdens on not only the patients who suffer from them, but the health care system as...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2014.2313082
更新日期：2014-07-01 00:00:00
abstract：:In this paper, we present a novel technique based on nonrigid image registration for myocardial motion estimation using both untagged and 3-D tagged MR images. The novel aspect of our technique is its simultaneous usage of complementary information from both untagged and 3-D tagged MR images. To estimate the motion wi...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2012.2188104
更新日期：2012-06-01 00:00:00
abstract：:An electrical impedance tomography (EIT) system that uses the optimal current method to inject currents and the regularized Newton-Raphson algorithm to reconstruct an image of resistivity distribution is discussed. Iterative methods to derive the optimal current patterns through iterative physical measurements are dev...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.192684
更新日期：1992-01-01 00:00:00
abstract：:Short-echo-time (TE) proton magnetic resonance spectroscopic imaging (MRSI) allows for simultaneously mapping a number of molecules in the brain, and has been recognized as an important tool for studying in vivo biochemistry in various neuroscience and disease applications. However, separation of the metabolite and ma...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2020.3048933
更新日期：2021-01-04 00:00:00
abstract：:Plane-wave-based ultrafast imaging has become the prevalent technique for non-conventional ultrasound imaging. The image quality, especially in terms of the suppression of artifacts, is generally compromised by reducing the number of transmissions for a higher frame rate. We hereby propose a new ultrafast imaging fram...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2017.2736423
更新日期：2018-02-01 00:00:00
abstract：:Magnetic particle imaging allows to determine the spatial distribution of magnetic nanoparticles in vivo. The system matrix in magnetic particle imaging is commonly acquired in a tedious calibration scan and requires to measure the system response at numerous positions in the field-of-view. In this paper, we propose a...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2013.2258029
更新日期：2013-08-01 00:00:00
abstract：:A new, sample independent optimization criterion for minimizing the effect of the imaging gradients, including the directional awareness they create, is defined for diffusion tensor imaging (DTI) experiments. The DTI linear algebraic framework is expanded to a normed space to design optimal diffusion gradient schemes ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2010.2090539
更新日期：2011-03-01 00:00:00
abstract：:An approach for estimating the motion of arteries in digital angiographic image sequences is proposed. Binary skeleton images are registered using an elastic registration algorithm in order to estimate the motion of the corresponding arteries. This algorithm operates recursively on the skeleton images by considering a...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.310876
更新日期：1994-01-01 00:00:00
abstract：:It is well known that the energy dependence of X-ray attenuation can be used to characterize materials. Yet, even with energy discriminating photon counting X-ray detectors, it is still unclear how to best form energy dependent measurements for spectral imaging. Common ideas include binning photon counts based on thei...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2010.2061862
更新日期：2011-01-01 00:00:00
abstract：:Decomposition of water and fat in magnetic resonance imaging (MRI) is important for biomedical research and clinical applications. In this paper, we propose a two-phased approach for the three-point water-fat decomposition problem. Our contribution consists of two components: 1) a background-masked Markov random field...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2011.2125980
更新日期：2011-08-01 00:00:00
abstract：:When more than two elemental materials are present in a given object, material quantification may not be robust and accurate when the routine two-material decomposition scheme in current dual energy CT imaging is employed. In this work, we present an innovative scheme to accomplish accurate three-material decompositio...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2020.2990347
更新日期：2020-11-01 00:00:00
abstract：:We propose an approach that combines an asymmetric fan-beam configuration and a new reconstruction algorithm to enhancing spatial resolution in computed tomography (CT). The asymmetric configuration can be achieved by changing the center of rotation (COR) from the conventional symmetric configuration. It does not, how...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/tmi.2004.840846
更新日期：2005-02-01 00:00:00
abstract：:Conventional ultrasound imaging is based on the scattering of sound from inhomogeneities in the density and the speed of sound and is often used in medicine to resolve pathologic compared to normal tissue. Here we demonstrate a difference-frequency ultrasound (dfUS) imaging method that is based on the interaction of t...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2019.2957280
更新日期：2020-05-01 00:00:00
abstract：:In magnetic resonance imaging (MRI), it is well-known that patient motion plays a significant role in the degradation of image quality. Although the case of translational in-plane motion (x-y-motion) has been studied by several researchers, the effect of rigid, translational out-of-plane motion (z-motion) has not yet ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.414611
更新日期：1995-01-01 00:00:00
abstract：:Active shape models bear a great promise for model-based medical image analysis. Their practical use, though, is undermined due to the need to train such models on large image databases. Automatic building of point distribution models (PDMs) has been successfully addressed and a number of autolandmarking techniques ar...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2008.2004819
更新日期：2008-11-01 00:00:00
abstract：:The quality of magnetic resonance imaging systems has improved to the point that motion is a major limitation in many examinations. Translational motion in the imaging plane causes the phase of the data to be corrupted. An algorithm using computer post-processing is proposed to correct the phase of the data, and hence...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.108589
更新日期：1991-01-01 00:00:00
abstract：:The high-frequency transceiver array based on the microstrip transmission line design is a promising technique for ultrahigh field magnetic resonance imaging (MRI) signal excitation and reception. However, with the increase of radio-frequency (RF) channels, the size of the ground plane in each microstrip coil element ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2009.2033597
更新日期：2010-01-01 00:00:00
abstract：:The hybrid magnetic resonance (MR)/X-ray suite (XMR) is a recently introduced imaging solution that provides new possibilities for guidance of cardiovascular catheterization procedures. We have previously described and validated a technique based on optical tracking to register MR and X-ray images obtained from the sl...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2005.856731
更新日期：2005-11-01 00:00:00
abstract：:A two-stage adaptive vector quantization scheme for radiographic image sequence coding is introduced. Each frame in the sequence is first decomposed into a set of vectors, corresponding to nonoverlapping spatially contiguous block of pixels. A codebook is generated using a training set of vectors drawn from the sequen...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.3938
更新日期：1988-01-01 00:00:00
abstract：:The reconstruction of MR quantitative susceptibility mapping (QSM) from local phase measurements is an ill posed inverse problem and different regularization strategies incorporating a priori information extracted from magnitude and phase images have been proposed. However, the anatomy observed in magnitude and phase ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2016.2544958
更新日期：2016-09-01 00:00:00
abstract：:A robust automated segmentation of abdominal organs can be crucial for computer aided diagnosis and laparoscopic surgery assistance. Many existing methods are specialized to the segmentation of individual organs and struggle to deal with the variability of the shape and position of abdominal organs. We present a gener...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2013.2265805
更新日期：2013-09-01 00:00:00
abstract：:Contrast source inversion-electrical properties tomography (CSI-EPT) is an iterative reconstruction method to retrieve the electrical properties (EPs) of tissues from magnetic resonance data. The method is based on integral representations of the electromagnetic field and has been shown to allow EP reconstructions of ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2018.2816125
更新日期：2018-09-01 00:00:00
abstract：:We present a dynamic atlas composed of neuromelanin-enhanced magnetic resonance brain images of 40 healthy subjects. The performance of this atlas is evaluated on the fully automated segmentation of two paired neuromelanin-rich brainstem healthy structures: the substantia nigra pars compacta and the locus coeruleus. W...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2018.2872852
更新日期：2019-03-01 00:00:00
abstract：:A new type of classifier combining an unsupervised and a supervised model was designed and applied to classification of malignant and benign masses on mammograms. The unsupervised model was based on an adaptive resonance theory (ART2) network which clustered the masses into a number of separate classes. The classes we...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.819327
更新日期：1999-12-01 00:00:00
abstract：:The authors describe a technique to reduce truncation artifacts in chemical shift images taken for in vivo magnetic resonance spectroscopy by using boundary information available from anatomic images. In this approach, high spatial frequency components are extrapolated from the observed data by making use of the bound...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.97578
更新日期：1991-01-01 00:00:00
abstract：:We propose a new spatio-temporal elastic registration algorithm for motion reconstruction from a series of images. The specific application is to estimate displacement fields from two-dimensional ultrasound sequences of the heart. The basic idea is to find a spatio-temporal deformation field that effectively compensat...
journal_title：IEEE transactions on medical imaging
pub_type： 临床试验,杂志文章
doi：10.1109/TMI.2005.852050
更新日期：2005-09-01 00:00:00
abstract：:We compare different possible scanning geometries for prostate photoacoustic tomography (PAT) while considering a realistic reconstruction scenario in which the limited view of the prostate and the directivity effect of the transducer are considered. Simulations and experiments confirm that an intra-operative configur...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2018.2855166
更新日期：2019-01-01 00:00:00
abstract：:Accurate localization of anatomical landmarks is an important step in medical imaging, as it provides useful prior information for subsequent image analysis and acquisition methods. It is particularly useful for initialization of automatic image analysis tools (e.g. segmentation and registration) and detection of scan...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2016.2597270
更新日期：2017-01-01 00:00:00
abstract：:Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of the breast has become an invaluable tool in the clinical work-up of patients suspected of having breast carcinoma. The purpose of this study is to introduce novel features extracted from the kinetics of contrast agent uptake imaged by a short (100 s) vi...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2013.2281984
更新日期：2014-02-01 00:00:00
abstract：:Cell or nucleus detection is a fundamental task in microscopy image analysis and has recently achieved state-of-the-art performance by using deep neural networks. However, training supervised deep models such as convolutional neural networks (CNNs) usually requires sufficient annotated image data, which is prohibitive...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2020.3042789
更新日期：2020-12-07 00:00:00
