Improvement in hypertension management in England: results from the Health Survey for England 2003.

abstract：OBJECTIVES:Arterial stiffness is associated with excess morbidity and mortality, independently of other cardiovascular risk factors. Age is the main determinant responsible for arterial wall changes leading to arterial stiffening. Environmental and genetic factors may however influence the magnitude of the effects of a...

journal_title：Journal of hypertension

authors： Lajemi M,Labat C,Gautier S,Lacolley P,Safar M,Asmar R,Cambien F,Benetos A

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Widely evaluated regarding the genetic make-up of essential hypertension are the renin-angiotensin-aldosterone system (RAAS) genes polymorphisms, whereas results are often not reproducible. METHOD:We thus focused on a large Fangshan population to explore association of thirteen polymorphisms in five genes o...

journal_title：Journal of hypertension

authors： Niu W,Qi Y,Hou S,Zhai X,Zhou W,Qiu C

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:To compare the anti-hypertensive effect of combination therapy versus a single drug regimen schedule (dose-titration or switching to a different drug class) in type 2 diabetic hypertensive patients with inadequate blood pressure (BP) control on monotherapy. DESIGN:Prospective, randomized, open-fashion, paral...

journal_title：Journal of hypertension

authors： Ruilope LM,de la Sierra A,Moreno E,Fernández R,Garrido J,de la Figuera M,de la Cámara AG,Coca A,Luque-Otero M

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:The pteridine cofactor tetrahydrobiopterin (BH4) has emerged as a critical determinant of endothelial nitric oxide synthase (eNOS) activity. When BH4 availability is limited, eNOS does not produce nitric oxide (NO) but instead generates superoxide. BH4 may reverse endothelial dysfunction due to cardiovascular...

journal_title：Journal of hypertension

authors： Kase H,Hashikabe Y,Uchida K,Nakanishi N,Hattori Y

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Hydroxymethylglutaryl coenzyme A (HMGCoA) reductase inhibitors have beneficial effects beyond their cholesterol-lowering properties. The antioxidant mechanism of HMGCoA reductase inhibitors is not completely understood. OBJECTIVES:To elucidate the antioxidant effect of simvastatin. METHODS:We studied the i...

journal_title：Journal of hypertension

authors： Carneado J,Alvarez de Sotomayor M,Perez-Guerrero C,Jimenez L,Herrera MD,Pamies E,Martin-Sanz MD,Stiefel P,Miranda M,Bravo L,Marhuenda E

更新日期：2002-03-01 00:00:00

abstract：:: Altered blood pressure (BP) is a common phenomenon in acute ischemic stroke (AIS), with high BP being the most frequent scenario. The pathophysiology of BP changes in AIS is complex and only partially understood. The available evidence indicates that extremely high BP during AIS is associated with a poor outcome. Im...

journal_title：Journal of hypertension

authors： Gąsecki D,Coca A,Cunha P,Hering D,Manios E,Lovic D,Zaninelli A,Sierra C,Kwarciany M,Narkiewicz K,Karaszewski B

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:Angiotensin (Ang) II increases reactive oxygen species (ROS), decreases nitric oxide (NO) bioavailability and promotes cardiovascular remodeling. ROS have been identified as critical second messengers of the trophic responses by Ang II. In rats with Ang II-induced hypertension, we investigated the role of ROS...

journal_title：Journal of hypertension

authors： Zhou MS,Jaimes EA,Raij L

更新日期：2005-09-01 00:00:00

abstract：:BMI represents an internal metabolic and physiological environment that plays a key role in development of high blood pressure (BP) for many Americans. African-American women have a higher prevalence of high BP and being overweight than men or other ethnic groups. This study examines the genetic-environmental interact...

journal_title：Journal of hypertension

authors： Taylor J,Sun YV,Chu J,Mosley TH,Kardia SL

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Apoptosis or programmed cell death could be greater than normal in various cardiovascular disorders, particularly in the heart. Apoptosis might contribute to remodeling of blood vessels in hypertension and could participate in regulation of vascular hypertrophy/hyperplasia. OBJECTIVE:To investigate apoptosi...

journal_title：Journal of hypertension

authors： Sharifi AM,Schiffrin EL

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:Despite data from animal models and observational studies that are generally supportive for the soy/isoflavones lowering blood pressure (BP) and improving vascular function, the current findings from clinical trials are still inconclusive. OBJECTIVES:To examine whether soy protein with isoflavones or isofla...

journal_title：Journal of hypertension

authors： Liu ZM,Ho SC,Chen YM,Woo J

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To gauge the effectiveness of a new Doppler test for renal artery stenosis (RAS), based on the pulsatility index of the blood flow velocity spectrum within several interlobar arteries of both kidneys. METHODS:Twenty normotensive volunteers and 49 hypertensive patients were investigated with ultrasound. Patie...

journal_title：Journal of hypertension

authors： Bardelli M,Jensen G,Volkmann R,Aurell M

更新日期：1992-09-01 00:00:00

abstract：OBJECTIVE:To determine the degree to which hypertension is a risk factor for macrovascular and microvascular complications in type 2 diabetes. DESIGN:Observational prospective study. SUBJECTS:Newly diagnosed Type 2 diabetic patients recruited into the UK Prospective Diabetes Study (n = 3648; mean age 52 years), 40% o...

journal_title：Journal of hypertension

authors：

更新日期：1993-03-01 00:00:00

abstract：OBJECTIVES:Polymorphisms in microRNA genes are related to the risk of ischemic stroke, but the association between miR-34b/c polymorphisms and the risk of ischemic stroke has not been reported. METHODS:MiR-34b/c rs2187473 and rs4938723 polymorphisms were genotyped by Snapshot assay among 495 controls and 492 ischemic ...

journal_title：Journal of hypertension

authors： Wei G,Liao C,Jian C,Liang L,Liu J,Tang Y,Wei Y

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:Arterial remodeling aims to maintain a constant circumferential wall stress (sigmac). A failing remodeling process is associated with stroke. Data on the relationship between chronic kidney disease and arterial remodeling are scarce. METHODS:We investigated the association between a lower glomerular filtrati...

journal_title：Journal of hypertension

authors： Hermans MM,Henry RM,Dekker JM,Nijpels G,Heine RJ,Stehouwer CD

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:Recent evidence indicates that reduced sleep duration may be associated with an increased risk of hypertension with possibly stronger effects among women than men. We therefore examined cross-sectional sex-specific associations of sleep duration with hypertension in a large population-based sample from the W...

journal_title：Journal of hypertension

authors： Stranges S,Dorn JM,Cappuccio FP,Donahue RP,Rafalson LB,Hovey KM,Freudenheim JL,Kandala NB,Miller MA,Trevisan M

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:To compare the effects of the angiotensin II receptor antagonist candesartan with the angiotensin-converting enzyme inhibitor enalapril on myocardial fibrosis evaluated by echoreflectivity analysis. METHODS:Hypertensive patients (n = 196) with echocardigraphically documented left ventricular hypertrophy were...

journal_title：Journal of hypertension

authors： Ciulla MM,Paliotti R,Esposito A,Cuspidi C,Muiesan ML,Rosei EA,Magrini F,Zanchetti A

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:Some cases of pseudopheochromocytoma have been described among hypertensive patients with obstructive sleep apnea (OSA). This study examined whether a pathological rise of urinary metanephrines is a common feature in hypertensive OSA patients and, in such a case, whether the ventilation treatment during sleep...

journal_title：Journal of hypertension

authors： Gilardini L,Lombardi C,Redaelli G,Mattaliano P,Fanari P,Cornacchia M,Scacchi M,Mai S,Ferronato P,Parati G,Invitti C

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:The interaction between trophoblasts and maternal endothelium is important for placental vascular modeling. Failure of uterine spiral artery transformation is linked to the etiopathology of preeclampsia. Antihypertensive medications used to control hypertension in early pregnancy can alter placental and circ...

journal_title：Journal of hypertension

authors： Xu B,Charlton F,Makris A,Hennessy A

更新日期：2014-05-01 00:00:00

abstract：:Haemorheological characteristics were measured in a group of 52 patients with essential arterial hypertension (HT), and were compared with those of a group of normotensive subjects. The relationships between the arterial blood pressure (BP), the echocardiographic indices of left ventricular hypertrophy (LVH), and the ...

journal_title：Journal of hypertension

authors： Zannad F,Voisin P,Brunotte F,Bruntz JF,Stoltz JF,Gilgenkrantz JM

更新日期：1988-04-01 00:00:00

abstract：OBJECTIVE:To examine the influence of genetic factors on plasma leptin levels. SUBJECTS AND METHODS:We measured plasma leptin levels, body mass index and body fat distribution in healthy young female monozygotic (n = 19) and dizygotic (n = 14) twins. The twin zygosity was verified by determination of short tandem repe...

journal_title：Journal of hypertension

authors： Narkiewicz K,Szczech R,Winnicki M,Chrostowska M,Pawlowski R,Lysiak-Szydlowska W,Choe I,Kato M,Sivitz WI,Krupa-Wojciechowska B,Somers VK

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the associations of high awake blood pressure (BP), high asleep BP, and nondipping BP, determined by ambulatory BP monitoring (ABPM), with left ventricular hypertrophy (LVH) and geometry. METHODS:Black and white participants (n = 687) in the Coronary Artery Risk Development in Young Adults study...

journal_title：Journal of hypertension

authors： Bello NA,Jaeger BC,Booth JN 3rd,Abdalla M,Anstey DE,Pugliese DN,Lewis CE,Gidding SS,Lloyd-Jones D,Shah SJ,Schwartz JE,Shikany JM,Muntner P,Shimbo D

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:In this cross-sectional study we compared the central aortic systolic pressure (CASP), peripheral brachial systolic pressure (PSP), peripheral brachial diastolic pressure (PDP) and augmentation index (AIx) between normotensive offspring of nonhypertensive parents (ONT) and normotensive offspring with at leas...

journal_title：Journal of hypertension

authors： Othman AS,Othman NI,Rosman A,Nudin SS,Rahman AR

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Patients with essential hypertension exhibit several red blood cell (RBC) ion transport abnormalities, insulin resistance (IR) and increased risk of developing type 2 diabetes. The aims of this study were to assess RBC ion transport activities under basal conditions and to test the in vivo effect of acute hyp...

journal_title：Journal of hypertension

authors： Suchánková G,Vlasáková Z,Zicha J,Vokurková M,Dobesová Z,Pelikánová T

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVES:To determine whether insulin sensitivity is impaired in normotensive offspring of essential hypertensives and to investigate how it relates to disturbed calcium metabolism. DESIGN:In 10 young lean, normotensive subjects with family histories of essential hypertension and in 10 age-matched controls we invest...

journal_title：Journal of hypertension

authors： Ohno Y,Suzuki H,Yamakawa H,Nakamura M,Otsuka K,Saruta T

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:The existence and localization of renin in situ was examined in human arteries under non-pathological conditions. DESIGN:Biochemical and immunohistochemical procedures were adopted to examine the existence of renin in human gastroepiploic arteries using an antibody raised against human recombinant renin or a...

journal_title：Journal of hypertension

authors： Okamura T,Aimi Y,Kimura H,Murakami K,Toda N

更新日期：1992-01-01 00:00:00

abstract：:Several myosin isoforms are expressed in smooth muscle, based upon both heavy and light chain polymorphisms. These myosin isoenzymes reveal distinct detachment rate constants, thus regulating the responsiveness of the VSMC contractile apparatus to Ca2+, as well as its energetical and mechanical behavior. ...

journal_title：Journal of hypertension

authors： Morano IL

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Genome-wide scans from Italy and China suggest a hypertension-susceptible locus between D2S2278 (nucleotides 11,245,080 - 11,245,358) and D2S168 (nucleotides 11,467,214 - 11,467,422) on chromosome 2. METHODS:We performed a large association study of polymorphisms in this region with blood pressure modulatio...

journal_title：Journal of hypertension

authors： Kamide K,Kokubo Y,Yang J,Tanaka C,Hanada H,Takiuchi S,Inamoto N,Banno M,Kawano Y,Okayama A,Tomoike H,Miyata T

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:The physiopathological mechanisms implicated in hypertensive heart disease are multi-factorial, including myocyte hypertrophy, apoptosis and myocardial remodelling. In this process, some hormonal and local growth factors have a regulatory influence. The aim of this study was to evaluate the potential role of ...

journal_title：Journal of hypertension

authors： Fernández-Solà J,Borrisser-Pairó F,Antúnez E,Tobías E

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:To study the interaction between the C(-344)T polymorphism and known determinants (age, body mass and dietary sodium) of blood pressure and plasma aldosterone. DESIGN:Cross-sectional and longitudinal (1980-1995) survey of male workers in southern Italy. SETTING:Medical centre of the Olivetti factories. PAR...

journal_title：Journal of hypertension

authors： Russo P,Siani A,Venezia A,Iacone R,Russo O,Barba G,D'Elia L,Cappuccio FP,Strazzullo P

更新日期：2002-09-01 00:00:00

abstract：CLINICAL STUDIES:In clinical renal transplantation studies, recipients of a renal graft from a donor with a genetic predisposition to hypertension had higher blood pressures and required more antihypertensive treatment than recipients of a renal graft from a normotensive donor. In addition, blood pressure normalization...

journal_title：Journal of hypertension

authors： Rettig R,Schmitt B,Pelzl B,Speck T

更新日期：1993-09-01 00:00:00