Abstract：
PURPOSE:To determine differences in size of cochlear nerves among subjects with deafness due to connexin 26 (Cx26) mutations, subjects with deafness of unknown origin, and normal hearing subjects by sagittal high-resolution magnetic resonance (HRMR) imaging of the temporal bone. MATERIALS AND METHODS:Cross-sectional and surface areas and volumetric measurements of the cochlear nerve and modiolus were made on HRMR images of the internal auditory canal (IAC) and inner ear in the 3 groups of children (groups 1, 2, and 3). Three-way comparisons of in vivo cochlear nerve measurements on HRMR imaging were made among 17 children with sensorineural hearing loss (SNHL) and no obvious etiology for the hearing loss (group 1), 7 children with profound SNHL due to a Cx26 mutation (group 2), and 10 normal hearing children (group 3). RESULTS:Children with profound SNHL of unknown cause and children with profound SNHL due to a connexin mutation displayed hypoplastic cochlear nerves as compared with normal controls. HRMR imaging of the temporal bone was accurately delineated potential problems with cochlear nerves in 2 of 17 instances where high-resolution computed tomography did not do so. CONCLUSIONS:Accurate and specific measurements of the cochlear nerve and related structures is possible on HRMR imaging of the temporal bone. The size of the cochlear nerve is mildly hypoplastic in children with profound SNHL of unknown causes or children with a deafness-causing Cx26 mutation. HRMR imaging is superior to high-resolution computed tomography in the investigation of profound SNHL in children.
journal_name
Am J Otolaryngoljournal_title
American journal of otolaryngologyauthors
Russo EE,Manolidis S,Morriss MCdoi
10.1016/j.amjoto.2005.09.007subject
Has Abstractpub_date
2006-05-01 00:00:00pages
166-72issue
3eissn
0196-0709issn
1532-818Xpii
S0196-0709(05)00176-6journal_volume
27pub_type
杂志文章abstract：:Type III frontal recess air cell as a cause of frontal sinus pneumocele has not been previously reported in literature. A 31-year-old woman with chronic history of sinusitis presented with pressure in the left eye on blowing the nose. Computed tomography examination of the orbits and paranasal sinuses with coronal and...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.amjoto.2009.01.001
更新日期：2010-05-01 00:00:00
abstract：:Previous studies have shown that propylene glycol causes inflammatory changes and cholesteatoma when applied to chinchilla middle ears. Vitamin A and synthetic analogues are essential for the normal differentiation of epithelial tissues. The purpose of this study was to determine whether the administration of isotreti...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/0196-0709(90)90163-p
更新日期：1990-01-01 00:00:00
abstract：:Sarcomatoid carcinomas of the larynx account for less than 1% of all malignant laryngeal tumors and there is currently no consensus regarding the clinical course or appropriate management of this disease. A case of sarcomatoid carcinoma of the larynx displaying rapid systemic progression after radiotherapy and a brief...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.amjoto.2005.02.017
更新日期：2005-11-01 00:00:00
abstract：PURPOSE:To present a prospective temporal bone fracture database, and study facial and cochleovestibular sequelae and their impact on quality of life. MATERIALS AND METHODS:Prospective study of consecutive cases of 39 patients with 45 temporal bone fractures over 11-month period in a university tertiary referral cente...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2014.12.011
更新日期：2015-05-01 00:00:00
abstract：PURPOSE:The purpose to this study is to identify correlations between pathology and dynamic contrast-enhanced magnetic resonance imaging (MRI) and to assess the utility of this technique in the evaluation of radiation response for head and neck cancer. MATERIALS AND METHODS:MRI was prospectively performed after radiot...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2004.11.011
更新日期：2005-05-01 00:00:00
abstract：OUTCOME OBJECTIVES:METHODS: Case Report, April 2016. RESULTS:A 27-year-old female presented with a three-week history of flu-like symptoms including sore throat, myalgia and insidious nasal congestion. Her hospital course was complicated by pancytopenia, extensive GI bleed of unknown origin and fever. Radiographic stu...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2018.07.017
更新日期：2018-01-01 00:00:00
abstract：:Observations from clinical and research applications of brain stem evoked response audiometry and electrocochleography have suggested that tone bursts of only a few milliseconds' duration can elicit frequency specific responses. Because such brief stimuli are not perceived as being total, the extent to which the audit...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(81)80027-0
更新日期：1981-05-01 00:00:00
abstract：:A newly devised pupillograph that can record the pupillary responses of both eyes simultaneously in a supine subject is described. Three patients with Meniere's disease in the attack and quasiattack stages showed a similar abnormality of pupillary light contraction on the affected side, compared with the unaffected si...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(85)80090-9
更新日期：1985-05-01 00:00:00
abstract：:Two cases of inner ear injury caused by suppressed sneezing are described. One patient experienced vestibular symptoms in the form of reflexogenic vertigo that was relieved by surgical section of the tensor tympani tendon. The other patient had a sudden severe permanent sensorineural hearing loss. It is proposed that ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(85)80027-2
更新日期：1985-11-01 00:00:00
abstract：PURPOSE:This study was performed to evaluate whether cartilage reconstruction of scutal wall defects diminishes retraction pocket and recurrent cholesteatoma, as compared with no cartilage reconstruction of the scutal defect. MATERIALS AND METHODS:A retrospective chart review from 1980 to 1993 was performed on all pat...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(98)90085-0
更新日期：1998-05-01 00:00:00
abstract：:The effectiveness of the auditory brainstem evoked response (ABR) test as a screening test for permanent hearing loss in neonates is examined in 32 published studies including 4,945 infants. Follow-up studies validating initial test failure were available for only 658 infants. Significant differences in methodology ex...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/s0196-0709(85)80050-8
更新日期：1985-03-01 00:00:00
abstract：:Zygomatic hemangioma is an extremely rare, benign, slow-growing tumor occurring mostly in adult women. The radiologic findings are diagnostic. Total excision of the tumor with primary reconstruction of the defect is the preferred treatment modality. We present a case of zygomatic hemangioma and a brief review of the l...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/s0196-0709(02)32429-3
更新日期：2003-05-01 00:00:00
abstract：:Intense sounds were delivered to 11 subjects with normal hearing both before and during administration of standard doses of four nonsteroidal anti-inflammatory drugs. After four days of aspirin treatment (3.9 g daily), the subjects' resting hearing levels raised by about 10 dB. Administration of intense sounds that ha...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(84)80033-2
更新日期：1984-07-01 00:00:00
abstract：OBJECTIVE:The clinical use of aminoglycoside antibiotics is limited in most countries because of auditory toxicity side effects. However, their use is common in developing countries because they are inexpensive and convenient. Salvia miltiorrhiza extracts are used clinically in China for their antioxidant properties. W...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2013.08.022
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:Currently, the first line treatment for Warthin's tumor (WT) is parotidectomy. There is a paucity of data evaluating the safety and efficacy of non-surgical treatments for patients not amenable to surgery. Ultrasound guided ethanol sclerotherapy (UGES) has been successfully used for the management of lymphan...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102813
更新日期：2021-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the added value of diffusion weighted magnetic resonance imaging (DW-MRI) in characterization of salivary gland lesions. STUDY DESIGN:A prospective study was carried out between January 2013, and March 2015. METHODS:The study included 46 patients. The consultant radiologist, who reviewed the sca...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2016.09.002
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:CT temporal bone scans are often performed to aid in surgical planning and management of cholesteatomas. With improvements in the resolution of CT scans today, it is now possible to obtain more information from these scans than before. The aim of this study is to compare findings on high resolution CT (HRCT) ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.amjoto.2014.02.015
更新日期：2014-07-01 00:00:00
abstract：PURPOSE:To assess the effectiveness of Buteyko breathing technique in patients with obstructive Eustachian tube dysfunction (ETD). MATERIALS AND METHODS:Fifty-one patients (77 ears) aged between 21 and 62 years were randomized to Buteyko breathing in conjunction with medical management (nasal steroid) group or medical...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.amjoto.2019.05.018
更新日期：2019-01-01 00:00:00
abstract：:Merkel cell carcinoma is a rare skin tumor that is thought to arise from epithelial cells that have undergone neuroendocrine differentiation. It usually presents in older adults and has a slight male predominance. The most frequent site of occurrence is in the head and neck. It is an aggressive disease that has a high...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2004.11.013
更新日期：2005-05-01 00:00:00
abstract：PURPOSE:This study was developed to test the hypothesis that intensive biofeedback and relaxation training may favorably affect chronic tinnitus. PATIENTS AND METHODS:Seven subjects with chronic tinnitus of moderate to severe intensity engaged in an intensive 5-month program of weekly, individual 90 minute sessions. A...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/0196-0709(92)90075-5
更新日期：1992-11-01 00:00:00
abstract：:A choristoma is a nonneoplastic proliferation of histologically normal tissue that forms at an abnormal site. It is extremely uncommon in the middle ear space. It appears to be a developmental abnormality and may be associated with abnormalities of adjacent structures. It usually occurs with unilateral conductive hear...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/s0196-0709(00)85011-5
更新日期：2000-03-01 00:00:00
abstract：:Ten guinea pigs were irradiated with 30 Gy of x-radiation. Five were killed on the eighth day after irradiation, and the remainder were killed at the sixteenth day after irradiation. At the time of death, examination was made of the ciliary activity and the fine structure of the middle ear mucosa. Serous effusion was ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(87)80008-x
更新日期：1987-07-01 00:00:00
abstract：:The distribution of minimal two-point discrimination values on the tongue and soft palate was investigated in normal subjects using electric stimulation. It was performed using square pulses of 0.35 ms duration, a rate 10 Hz, a voltage between 3.5 and 7.0 with an average of 4.09 using two silver-silver chloride electr...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/0196-0709(89)90110-5
更新日期：1989-09-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to report 2 cases of extramedullary plasmacytoma (EP) with localization to middle ear that were diagnosed and managed in our department. METHODS:The first patient was a 60-year-old man with progressive hearing loss, tinnitus, recurrent episodes of otalgia, and otorrhea in his right e...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.amjoto.2008.07.004
更新日期：2009-09-01 00:00:00
abstract：:Lightning induced damage to the ear is multifaceted. The seventh and eighth cranial nerves, the labyrinthine system, and the tympanic membrane are most commonly injured. A case report demonstrating all these injuries is presented. ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(80)80036-6
更新日期：1980-08-01 00:00:00
abstract：PURPOSE:To demonstrate non-inferiority of eberconazole 1% otic solution to clotrimazole 1% solution, and to compare their safety profiles in the treatment of otomycosis. MATERIALS AND METHODS:Multicenter, randomized, double-blind, active treatment-controlled phase 3 clinical trial. One hundred and ninety patients with...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.amjoto.2018.03.017
更新日期：2018-01-01 00:00:00
abstract：:Metastatic calcification (MC) commonly results secondary to phosphorus and calcium dysregulation in end-stage renal disease (ESRD). Only once before has MC been reported to involve a true vocal cord. A 35-year-old man with ESRD and secondary hyperparathyroidism was evaluated for hoarseness. Three years ago, he underwe...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2008.04.006
更新日期：2009-05-01 00:00:00
abstract：PURPOSE:To investigate the correlation between internet search activity and epistaxis-related Emergency Department visits. MATERIALS AND METHODS:Data from Google Trends were obtained (www.google.com/trends) for the search term "nosebleed" in Erie County, Pennsylvania during a five-year period. All epistaxis-related CP...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2018.07.012
更新日期：2018-01-01 00:00:00
abstract：PURPOSE:In this article, we study the use of the American Academy of Otolaryngology-Head and Neck Surgery recommendations regarding coagulation screening tests before tonsillectomy and adenoidectomy by ear, nose, and throat (ENT) physicians in Israel and offer insights into the reasons for accepting/declining this reco...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2004.02.002
更新日期：2004-07-01 00:00:00
abstract：:The present report describes an original surgical procedure for the mandibular reconstruction of 2 different defects using a single fibular flap. In addition to the habitual osteotomies, we resected a bone fragment from the middle portion of the flap, with care taken to maintain the integrity of the pedicle throughout...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2007.07.003
更新日期：2008-05-01 00:00:00
