Abstract：
:Ten guinea pigs were irradiated with 30 Gy of x-radiation. Five were killed on the eighth day after irradiation, and the remainder were killed at the sixteenth day after irradiation. At the time of death, examination was made of the ciliary activity and the fine structure of the middle ear mucosa. Serous effusion was found in each tympanic cavity of all animals. It was shown also that the guinea pig, when irradiated with 30 Gy of x-radiation, exhibits pathologic abnormalities similar to those in humans with otitis media with effusion: degeneration of cilia or ciliated cells and changes in the vascular system (capillary injury and increased capillary permeability). Functional examinations showed that x-ray irradiation has delayed effects on ciliary activity, and the effects are much greater at the sixteenth day than at the eighth day. We speculate that the accumulation of effusion can be, at least partially, a consequence of ciliary dysfunction. The induction of sterile effusion by the use of x-ray irradiation provides a unique animal model for chronic otitis media with effusion of the serous type.
journal_name
Am J Otolaryngoljournal_title
American journal of otolaryngologyauthors
Ohashi Y,Nakai Y,Ikeoka H,Esaki Y,Koshimo H,Onoyama Ydoi
10.1016/s0196-0709(87)80008-xsubject
Has Abstractpub_date
1987-07-01 00:00:00pages
223-35issue
4eissn
0196-0709issn
1532-818Xpii
S0196-0709(87)80008-Xjournal_volume
8pub_type
杂志文章abstract：:Aging is associated with changes in voice and/or laryngeal protective reflexes in humans. To assess the role of the laryngeal muscles in this change, we have examined in vitro thyroarytenoid (vocalis) muscles excised from the larynxes of young and old baboons. Contractile properties, fatigue characteristics, and resti...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(87)80029-7
更新日期：1987-03-01 00:00:00
abstract：:The technique of intraoperative evoked electromyography is described in detail. Direct intraoperative stimulation of the exposed facial nerve identified the sites of nerve impulse conduction blocks in 16 of 18 patients who needed decompression for Bell' s palsy. In order to determine the site of impulse conduction blo...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(82)80066-5
更新日期：1982-07-01 00:00:00
abstract：PURPOSE:The dizziness handicap inventory (DHI) is widely used to evaluate self-perceived handicap due to dizziness, and is known to correlate with vestibular function tests in chronic dizziness. However, whether DHI reflects subjective symptoms during the acute phase has not been studied. This study aims to investigate...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.amjoto.2015.07.011
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:The goals of successful reconstructive surgery are to restore function and cosmesis; however, limitation of resources can become an important consideration in low-middle income countries. METHODS:We describe our experience using the submental island flap in two cases during a short-term surgical camp in Eas...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2016.09.012
更新日期：2017-01-01 00:00:00
abstract：:The effectiveness of the auditory brainstem evoked response (ABR) test as a screening test for permanent hearing loss in neonates is examined in 32 published studies including 4,945 infants. Follow-up studies validating initial test failure were available for only 658 infants. Significant differences in methodology ex...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/s0196-0709(85)80050-8
更新日期：1985-03-01 00:00:00
abstract：PURPOSE:Lymph node density(LND) has been shown to be a better prognosticator than conventional nodal classification to predict prognosis for squamous cell carcinoma(SCC) of the oral cavity. However, studies focusing on subsites of oral cancer are meager. The role of LND for buccal SCC was evaluated in this study. METH...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2017.05.001
更新日期：2017-01-01 00:00:00
abstract：:Sarcoidosis is a systemic chronic granulomatous disease of unknown etiology. Although it most commonly affects African-Americans, Scandinavians, and the Irish, individuals of all races and ethnicities are susceptible. The otolaryngologist will most frequently encounter sarcoidosis involving the sinonasal region; howev...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1053/ajot.2002.28783
更新日期：2002-01-01 00:00:00
abstract：:We report the use of potassium titanyl phosphate laser-assisted tympanoplasty in amputations of the malleus and incus in 2 patients with cholesteatoma medial to those ossicles that had not destroyed the ossicular chain continuity. In both cases, the laser successfully removed portions of the ossicles to allow removal ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1053/ajot.2001.28081
更新日期：2001-11-01 00:00:00
abstract：:Leiomyosarcoma of the paranasal sinuses is uncommon and has an aggressive clinical behavior. Only 28 cases have been described in the literature, and, of these, only 3 patients treated with surgery had a disease-free survival. In this report, we describe the clinical history of a 57-year-old woman with a leiomyosarcom...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1053/ajot.2002.30628
更新日期：2002-03-01 00:00:00
abstract：:In vitro studies of B-cells immortalized by Epstein-Barr Virus (EBV) have shown that B-cell leukemia/lymphoma-2 (bcl-2) protein expression is upregulated by the EBV-latency-associated antigen, latent membrane protein 1 (LMP1). The same phenomenon has also been observed in epithelial cells in vitro. However, such corre...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1053/ajot.2001.28071
更新日期：2001-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the added value of diffusion weighted magnetic resonance imaging (DW-MRI) in characterization of salivary gland lesions. STUDY DESIGN:A prospective study was carried out between January 2013, and March 2015. METHODS:The study included 46 patients. The consultant radiologist, who reviewed the sca...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2016.09.002
更新日期：2017-01-01 00:00:00
abstract：:Cervical necrotizing fasciitis is a rapidly progressive and devastating infection that is usually caused by a polymicrobial infection including group A Streptococcus and anaerobes. We present a case of a newly diagnosed diabetic man who underwent transoral drainage of a Klebsiella pneumoniae paraglottic abscess, which...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2012.05.009
更新日期：2012-11-01 00:00:00
abstract：:A 61-year-old woman presented with painful ophthalmoplegia, Tolosa-Hunt syndrome. The patient had undergone a placement of dental implant 5 months before the presentation and had a local maxillary sinusitis 1 month later. She had not been aware of any preceding head trauma or infection. On examination, the patient sho...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2011.08.002
更新日期：2012-05-01 00:00:00
abstract：PURPOSE:Squamous cell carcinoma is a common entity among adult head and neck cancer patients, with many requiring reconstruction post resection. Conversely, this entity is rare among children with major reconstruction even more unique. This case and the concomitant review of literature highlight the intricacies of pedi...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2014.07.004
更新日期：2014-11-01 00:00:00
abstract：PURPOSE:The aim of our study was to determine whether the combination of intratympanic (IT) corticosteroid with melatonin could be associated with decreased tinnitus in patients with unilateral acute idiopathic tinnitus developed within 3months. MATERIALS AND METHODS:We evaluated this hypothesis through a prospective,...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.amjoto.2014.06.009
更新日期：2014-09-01 00:00:00
abstract：PURPOSE:The objective of this study is to determine the results of functional endoscopic sinus surgeries (FESS) for chronic rhinosinusitis with polyps and assess the association between surgery and specific quality of life outcomes. MATERIALS AND METHODS:A prospective study was performed in a tertiary referral center....
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2014.09.003
更新日期：2015-01-01 00:00:00
abstract：:Meniere's disease is a peripheral audiovestibular disorder characterized by vertigo, hearing loss, tinnitus, and aural fullness. Management of these symptoms includes medical and surgical treatment. Many patients with Meniere's disease can be managed using nonablative therapy, such as intratympanic steroids and endoly...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.amjoto.2020.102817
更新日期：2021-01-01 00:00:00
abstract：PURPOSE:This study presents our experience with 728 patients treated in our department for well-differentiated thyroid carcinoma between 1954-1994. MATERIALS AND METHODS:The retrospective evaluation of the prognostic implications of the clinical and pathological findings was performed. Age, sex, histological variants,...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(96)90074-5
更新日期：1996-11-01 00:00:00
abstract：PURPOSE:The standard treatment for patients with early glottic carcinoma in Israel has been radiotherapy. In recent years, encouraging results with laryngo-microscopic carbon dioxide laser surgery as a treatment for early glottic carcinoma has changed our treatment strategy. We conducted a retrospective study to invest...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1053/ajot.2003.2
更新日期：2003-01-01 00:00:00
abstract：PURPOSE:To report the result of transcanal tympanoplasty using Lyodura as a graft. MATERIALS AND METHODS:One hundred thirty-seven patients with chronic suppurative otitis media with a dry perforation were considered for tympanoplasty. The transcanal permeatal approach was adopted. Lyodura as a ready-made graft was use...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(99)90000-5
更新日期：1999-07-01 00:00:00
abstract：:A regional random pattern flap is described which may be used to cover the mastoid area in cases in which the inferior auricle and adjacent tissue have been removed by trauma or surgery. The viability of this vascularized tissue offers a distinct advantage over skin grafting when protection of exposed facial nerve and...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(88)80032-2
更新日期：1988-09-01 00:00:00
abstract：OBJECTIVE:To investigate whether the racial/ethnical disparity of nasopharyngeal carcinoma exists among the four major ethical groups in the United States named Asians, Caucasians, African Americans and Hispanics between the years of 1973 to 2013 using the Surveillance, Epidemiology, and End Result (SEER) database. ME...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2019.102288
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Cervical lymphadenopathy could be a manifestation of occult nasopharyngeal carcinoma (NPC). Epstein-Barr virus (EBV) is frequently detected in NPC, and its malignant transformation is associated through the action of the oncoprotein latent membrane protein-1 (LMP-1). PURPOSE:The aim of this study was to inv...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2008.02.013
更新日期：2009-03-01 00:00:00
abstract：OBJECTIVE:The objective of the study was to review the diagnosis and treatment of primary immunodeficiency disease (PID) and the role of otolaryngologists in the management of PID. METHODS:A search was conducted of PubMed and the Web sites of organizations for PID patients for literature pertaining to the diagnosis an...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.amjoto.2010.05.001
更新日期：2011-07-01 00:00:00
abstract：:Samples of middle ear effusions from 10 children with secretory otitis media and from 10 children with chronic suppurative otitis media were subjected to qualitative and quantitative bacteriologic analysis. In addition, secretory immunoglobulin A (SlgA)- and IgG-coated bacteria were evaluated using the immunofluoresce...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/0196-0709(91)90147-8
更新日期：1991-05-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to determine the immediate effects of intraperitoneal doses of gentamicin (GM) which would result in variable degrees of destruction of crista ampullary hair cells of frogs. This information will serve as a baseline guide to cell regeneration experiments on the damaged vestibular sens...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2004.08.007
更新日期：2005-03-01 00:00:00
abstract：PURPOSE:Facial nerve monitoring is often used to predict postoperative facial function after acoustic neuroma tumor removal. In this study, three methods of predicting facial nerve function were compared. These methods used various parameters of the evoked electromyographic monitoring. MATERIALS AND METHODS:Thirty-fou...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(98)90103-x
更新日期：1998-03-01 00:00:00
abstract：:Melanotic neuroectodermal tumor of infancy is a rare condition that is most commonly found within the head and neck regions. We present a 4-month-old boy with a melanotic neuroectodermal tumor of infancy of his maxilla. Because of the fairly high recurrence rate, the operating microscope was used after surgical excisi...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1053/ajot.2001.20696
更新日期：2001-01-01 00:00:00
abstract：:Rupture of the carotid artery has been one of the most feared postoperative complications in head and neck cancer patients. Traditional management of carotid artery rupture has been disappointing, and morbidity and mortality have been high. Experience with carotid artery rupture at the authors' institution over the pa...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(86)80009-6
更新日期：1986-05-01 00:00:00
abstract：PURPOSE:The authors conducted a prospective, comparative clinical trial for the purpose of additional effect of lipoprostaglandin E 1 (lipo-PGE 1 ) on sudden hearing loss. MATERIALS AND METHODS:With the approval of the institute ethics committee, a total of 128 consecutive patients with diagnoses of sudden hearing los...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.amjoto.2005.01.009
更新日期：2005-07-01 00:00:00
