Immunoglobulin-coated bacteria in effusions from secretory and chronic suppurative otitis media.

Abstract:

:Samples of middle ear effusions from 10 children with secretory otitis media and from 10 children with chronic suppurative otitis media were subjected to qualitative and quantitative bacteriologic analysis. In addition, secretory immunoglobulin A (SlgA)- and IgG-coated bacteria were evaluated using the immunofluorescence technique. Secretory otitis media effusions harbored few, if any, immunoglobulin-coated bacteria, whereas chronic otitis media effusions as a rule had heavily IgG- and SlgA-coated bacteria. However, those chronic otitis media effusions that were culture positive for Pseudomonas aeruginosa had no immunoglobulin-coated bacteria. The effusions of very young children were completely devoid of SlgA-coated bacteria. This study demonstrates that, based on the immunoglobulin coating of bacteria obtained from the middle ear cleft, one can evaluate immunologic response during otitis media.

journal_name

Am J Otolaryngol

authors

Stenfors LE,Räisänen S

doi

10.1016/0196-0709(91)90147-8

subject

Has Abstract

pub_date

1991-05-01 00:00:00

pages

161-4

issue

3

eissn

0196-0709

issn

1532-818X

pii

0196-0709(91)90147-8

journal_volume

12

pub_type

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