Abstract：
PURPOSE:The purpose of this retrospective cohort study was to determine whether there is a difference in the sensitivity of chest computed tomography (CT) versus 18F-fluorodeoxyglucose positron emission tomography with low-dose nonenhanced CT (18F-FDG PET/CT or PET/CT) in the detection of distant metastases in head and neck cancer, within a tertiary care setting. MATERIALS AND METHODS:Patients with head and neck cancer, and known distant metastases, who underwent both 18F-FDG PET/CT with integrated low-dose nonenhanced CT and diagnostic chest CT prior to initiation of therapy from 2008 to 2017 were included. Two head and neck radiologists, blinded to all patient information and to each other's readings, reviewed the PET/CT or CT chest images for each patient and identified whether distant metastases were present. No radiologist read both modalities for a single patient. Concordance between imaging modalities was quantitatively analyzed using McNemar's test. RESULTS:27 patients were included. McNemar's mid p-value analysis showed no significant difference in the detection of distant metastases (p = .6875). However, PET/CT detected distant metastases in three patients that chest CT did not, while chest CT identified distant metastatic disease in two patients that were negative on PET/CT. CONCLUSIONS:While this study did not identify a statistically significant difference in sensitivity, five patients had distant metastases identified on only one of the two modalities. Use of a single modality would have resulted in inaccurate staging in 7-11% of patients in our study. The use of both modalities offers the greatest accuracy when providing stage-adapted oncologic treatment.
journal_name
Am J Otolaryngoljournal_title
American journal of otolaryngologyauthors
Mur T,Sambhu KM,Mahajan A,Payabvash S,Fernandez J,Edwards HAdoi
10.1016/j.amjoto.2020.102662subject
Has Abstractpub_date
2020-01-01 00:00:00pages
102662issue
6eissn
0196-0709issn
1532-818Xpii
S0196-0709(20)30356-2journal_volume
41pub_type
杂志文章abstract：:Thromboses in Trousseau's syndrome are typically confined to the vascular system of the extremities and viscera. The authors report a case of sequential bilateral internal and external jugular-vein thromboses secondary to this paraneoplastic hypercoagulable state. The etiologies of commonly encountered head and neck v...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(85)80019-3
更新日期：1985-09-01 00:00:00
abstract：BACKGROUND:Primary non-Hodgkin lymphomas (NHLs) of the sinonasal tract comprise a rare entity that constitutes 1.5% of all NHLs and 2.2% of extranodal lymphomas in the whites. Clinical diagnosis may be very challenging because of the variety and low specificity of the presenting symptoms and signs. METHODS-RESULTS:We ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2005.09.019
更新日期：2006-05-01 00:00:00
abstract：PURPOSE:To report our long-term results in surgical management of invasive intralabyrinthine cholesteatoma. MATERIAL AND METHODS:The study is a case series in a tertiary referral center. Retrospective chart review of all mastoid operations performed for chronic ear disease between 1994 and 2019 at University Health Ne...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102407
更新日期：2020-01-01 00:00:00
abstract：:This case is a single submandibular gland mumps viral infection patient without parotid gland involvement who developed complications of meningitis and orchitis. Since spontaneous remission is common in mumps viral infection, missing opportunities for exact diagnosis is frequent. As in this case, single submandibular ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2013.02.004
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to report 2 cases of extramedullary plasmacytoma (EP) with localization to middle ear that were diagnosed and managed in our department. METHODS:The first patient was a 60-year-old man with progressive hearing loss, tinnitus, recurrent episodes of otalgia, and otorrhea in his right e...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.amjoto.2008.07.004
更新日期：2009-09-01 00:00:00
abstract：OBJECTIVE:Syphilis is a sexually transmitted infection with various presentations. Although, oropharyngeal manifestations are known to occur, the purpose of this study is to present the first case series in which the lesions were initially mistaken for human-papillomavirus (HPV)-related oropharyngeal squamous cell carc...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2019.01.005
更新日期：2019-01-01 00:00:00
abstract：:Castleman disease is a rare lymphoproliferative disorder with two primary subtypes that vary in presentation and course. Unicentric Castleman disease (UCD) presents as a solitary mass, most commonly in the mediastinum, and rarely in the head and neck. In contrast to multicentric Castleman disease (MCD), which features...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.amjoto.2012.11.007
更新日期：2013-05-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to determine the immediate effects of intraperitoneal doses of gentamicin (GM) which would result in variable degrees of destruction of crista ampullary hair cells of frogs. This information will serve as a baseline guide to cell regeneration experiments on the damaged vestibular sens...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2004.08.007
更新日期：2005-03-01 00:00:00
abstract：BACKGROUND:Currently described endoscopic techniques for subtotal resections of the maxilla include endoscopic medial maxillectomy and extended endoscopic medial maxillectomy; however, a complete resection of the maxilla is sometimes warranted. We describe a combined transoral and endoscopic technique for total and sub...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2010.07.023
更新日期：2011-09-01 00:00:00
abstract：:Sinus nitric oxide (NO) measurements present a novel and promising approach to help overcome difficulties and confounding variables associated with nasal NO measurements such as the nasal cycle, ostial patency, and individual contribution to total NO production of each sinus. Conflicting results reported on nasal NO m...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2013.01.007
更新日期：2013-07-01 00:00:00
abstract：PURPOSE:The non-invasive diagnosis of acute rhinosinusitis (ARS) remains an unresolved problem of modern otolaryngology. Analog diaphanoscopy of reduced transillumination (shading) could be enhanced by a digital image processing of the maxillary sinuses. By this means, the limited ergonomics of this safe and low-cost m...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102444
更新日期：2020-01-01 00:00:00
abstract：:Acquired tracheal pouch known also as tracheocele is a rare air-filled diverticulum of tracheal pars membranacea. This disease may be due to esophageal or tracheal surgery, orotracheal intubation, or increased intralunimal pressure through a weak area of tracheal wall. When symptomatic and medical therapy is insuffici...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2009.02.011
更新日期：2010-07-01 00:00:00
abstract：:This clinical review presents a survey of the different types of epithelial neoplasms in the parotid gland. The incidence, histopathological classification, grade of malignancy, and staging system are discussed. Diagnostic procedures are reviewed and a scheme for treatment is proposed for the different types of epithe...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/s0196-0709(80)80011-1
更新日期：1980-02-01 00:00:00
abstract：OBJECTIVE:This study aimed to investigate the reliability of temporal bone high-resolution CT (HRCT) in patients with traumatic facial paralysis. METHODS:HRCT with cross-sectional scanning and multi-planar reformation (MPR) was performed on 26 cases with traumatic facial paralysis, and the preoperative imaging manifes...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2017.12.003
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:Determine the outcome of hearing in Meniere's Disease (MD) after antiviral treatment. STUDY DESIGN:Prospective study. SETTING:University Hospital. METHODS:Thirty one new patients with a diagnosis of MD were treated with antiviral drugs during 2012. Acyclovir or valacyclovir was used depending on insurance ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2014.03.016
更新日期：2015-05-01 00:00:00
abstract：:A regional random pattern flap is described which may be used to cover the mastoid area in cases in which the inferior auricle and adjacent tissue have been removed by trauma or surgery. The viability of this vascularized tissue offers a distinct advantage over skin grafting when protection of exposed facial nerve and...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(88)80032-2
更新日期：1988-09-01 00:00:00
abstract：OUTCOME OBJECTIVES:METHODS: Case Report, April 2016. RESULTS:A 27-year-old female presented with a three-week history of flu-like symptoms including sore throat, myalgia and insidious nasal congestion. Her hospital course was complicated by pancytopenia, extensive GI bleed of unknown origin and fever. Radiographic stu...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2018.07.017
更新日期：2018-01-01 00:00:00
abstract：INTRODUCTION:Blindly administered bilateral (B/L) superior laryngeal nerve (SLN) blocks, have been used to decrease the perioperative stress response of endoscopic laryngosurgeries. Use of ultrasound (USG) for giving these blocks is more likely to be successful, with fewer complications. We evaluated the efficacy of US...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.amjoto.2018.09.004
更新日期：2019-01-01 00:00:00
abstract：PURPOSE:Determine correlation of malignancy rates between fine needle aspiration (FNA) biopsy and surgical specimen in an urban academic environment. METHODS:Retrospective review at an academic medical center of fine needle aspiration biopsies and surgical specimens in a head and neck otolaryngology practice between 2...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2013.12.014
更新日期：2014-05-01 00:00:00
abstract：BACKGROUND:The receptor activator for nuclear factor-κB ligand (RANKL) and osteoprotegerin (OPG) are the key factors controlling the osteoclast and osteoblast action in the bone. PURPOSE:The study objective was to investigate the expression level of RANKL and OPG in cholesteatoma and granulation tissue, and to assess ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2009.06.004
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVES:Rare diseases are often poorly understood, and this study sought to investigate the incidence of a rare disease entity, basaloid squamous cell carcinoma (BSCC) of the oral cavity (OC) at a tertiary care medical center and to assess its clinical outcomes. METHODS:The aim of this study was to collect data in ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102645
更新日期：2020-01-01 00:00:00
abstract：PURPOSE:Chronic tonsillitis (TC) is among the most common bacterial diseases in pediatric otolaryngology. We aimed to evaluate the expression of glycogen synthase kinase 3β (GSK-3β) in a cohort of children with chronic tonsillitis (TC), and the correlation between GSK-3β activity index and inflammatory profiles of TC. ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2018.03.005
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVES:In the literature, diabetes mellitus was mentioned as one of the etiologic factors of olfactory disorder. However, association between olfactory dysfunction and complications of type 2 diabetes mellitus is unclear. The aim of this study was to determine if there is any correlation between olfactory dysfuncti...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2019.102365
更新日期：2020-01-01 00:00:00
abstract：:We aimed to investigate the relationship between peripheral vertigo and inflammation by using the neutrophil-to-lymphocyte ratio (NLR) as an inflammatory marker. We recruited 103 patients with peripheral vertigo (71 women, 32 men; mean age, 39.8 ± 14.7 years) who presented to the Otolaryngology Department of Dumlupina...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2014.08.004
更新日期：2014-11-01 00:00:00
abstract：OBJECTIVES:A case of pediatric otogenic lateral sinus thrombosis is reported, followed by a substantive literature review. DESIGN:104 patients were reviewed, culled from published case reports from 1993 to 2011 on the PubMed database. METHODS:All full text case reports on the PubMed database from 1993 to 2011 with pa...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2012.09.011
更新日期：2013-03-01 00:00:00
abstract：:The effectiveness of the auditory brainstem evoked response (ABR) test as a screening test for permanent hearing loss in neonates is examined in 32 published studies including 4,945 infants. Follow-up studies validating initial test failure were available for only 658 infants. Significant differences in methodology ex...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/s0196-0709(85)80050-8
更新日期：1985-03-01 00:00:00
abstract：PURPOSE:To review rates of post-tonsillectomy hemorrhage (PTH) at a quaternary medical center, including the impact of narcotic versus nonsteroidal anti-inflammatory drug (NSAID) postoperative pain management. MATERIALS AND METHODS:A retrospective review was performed of tonsillectomies conducted at a single instituti...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.amjoto.2018.03.028
更新日期：2018-01-01 00:00:00
abstract：:The first case of the endoscopic intranasal excision of chondromyxoid fibroma as an outgrowth of the ethmoid bone is reported. This case appears to represent the second reported type of recurrence of CMF in the head and neck area and the second type of CMF originating in the ethmoid. ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/0196-0709(95)90105-1
更新日期：1995-05-01 00:00:00
abstract：OBJECTIVES/HYPOTHESIS:The aim of the study was to introduce and study the role of standardized views for ultrasound of the major salivary glands in resident learning and retention. STUDY DESIGN:Methods description and prospective case series. METHODS:Five otolaryngology residents and two patient models were recruited...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102734
更新日期：2020-01-01 00:00:00
abstract：:The characteristics of response of 98 vestibular nuclei neurons were investigated in the barbiturate anesthetized cat. All type I and type II neurons (tonic and kinetic) responded to stimulation of the horizontal canals with step and impulse accelerations. Seventy-seven (79 per cent) neurons of all types demonstrated ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(80)80019-6
更新日期：1980-11-01 00:00:00
