Primary nasal non-Hodgkin lymphomas presented initially as benign disease.

Abstract:

BACKGROUND:Primary non-Hodgkin lymphomas (NHLs) of the sinonasal tract comprise a rare entity that constitutes 1.5% of all NHLs and 2.2% of extranodal lymphomas in the whites. Clinical diagnosis may be very challenging because of the variety and low specificity of the presenting symptoms and signs. METHODS-RESULTS:We present three cases of NHLs, initially diagnosed as benign diseases. All three cases have been eventually correctly diagnosed and treated in our hospital between January 2000 and December 2003. The patients have been under close follow-up from 11 to 36 months after the initial treatment. One of them remains without clinical or radiological evidence of recurrence, whereas the two others died 11 and 16 months after the initial diagnosis. CONCLUSION:It is important to underline that atypical or persistent symptoms of rhinosinusitis may represent the initial expression of a more serious condition such as deep fungal infection, vasculitis, lymphoma, or other malignancy.

journal_name

Am J Otolaryngol

authors

Kyrmizakis DE,Hajiioannou JK,Koutsopoulos AV,Papadaki E,Papadakis D,Bizakis J,Velegrakis G

doi

10.1016/j.amjoto.2005.09.019

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

217-20

issue

3

eissn

0196-0709

issn

1532-818X

pii

S0196-0709(05)00178-X

journal_volume

27

pub_type

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