Objective evaluation of odor loss in COVID-19 and other suspected cases.

Abstract:

INTRODUCTION:COVID-19 is a pandemic disease known with one of the symptoms is sudden onset anosmia. This symptom sometimes may be the only sign of the disease, therefore it must be research widely. OBJECTIVE:We aim to evaluate odor dysfunction in COVID-19 patients objectively and safely without any risk of transmitting the disease. METHODS:The odor threshold test was performed on 105 patients hospitalized at the XXXX Training and Research Hospital on the COVID-19 pandemic service before any treatment began. Odor threshold was tested using a modification of the Connecticut Chemosensory Clinical Research Center olfactory function test. COVID-19 signs and symptoms, PCR test results, thorax computed tomography (CT) findings, and length of hospital stay were recorded. Odor tests were scored between 0-8, 0-1 anosmia, 2-3 severely hyposmia, 4 moderate hyposmia, 5 mild hyposmia, 6 and above normosmia. RESULTS:Forty-one (39%) of the 105 patients were diagnosed with COVID-19 after the PCR results. Patients with an odor threshold score < 5 were classified as "Smell-Impaired Group", patients with an odor threshold score ≥ 5 were placed in "Smell Intact Group". The incidence of female patients in smell-impaired group was significantly higher (p ˂ 0.05). The proportion of patients who were PCR-positive for COVID-19 in smell-impaired group was significantly higher (p ˂ 0.05) than in smell intact group. Among patients with an odor threshold score from 0 to 1 (anosmic; n = 15), 12 (80%) demonstrated PCR positivity (p < 0.0001). CONCLUSION:Anosmia can be predictive for coronavirus disease. Odor threshold test can be helpful for diagnosis.

journal_name

Am J Otolaryngol

authors

Seden N,Yiğit E,Yiğit Ö,Kaygısız İ

doi

10.1016/j.amjoto.2020.102761

subject

Has Abstract

pub_date

2021-01-01 00:00:00

pages

102761

issue

1

eissn

0196-0709

issn

1532-818X

pii

S0196-0709(20)30455-5

journal_volume

42

pub_type

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