Epstein-Barr virus and cancers of the head and neck.

Abstract:

:Denis Burkitt pioneered the association of viruses and cancer in humans with his observations of lymphomatous tumors in children in equatorial Africa. The Epstein-Barr virus (EBV), a human B lymphotrophic herpes virus, is strongly associated with undifferentiated carcinoma of the nasopharynx and African-type Burkitt's lymphoma. More recently, an association of this virus with other epithelial neoplasms, lymphomas, and immunodeficiency-related malignant and nonmalignant conditions has been reported. Since many of these tumors are rare, much of the information is based on sporadic reports and relatively small series of patients. The purpose of this report is to review the literature and examine the growing association of EBV with various head and neck malignancies.

journal_name

Am J Otolaryngol

authors

Goldenberg D,Golz A,Netzer A,Rosenblatt E,Rachmiel A,Goldenberg RF,Joachims HZ

doi

10.1053/ajot.2001.23429

subject

Has Abstract

pub_date

2001-05-01 00:00:00

pages

197-205

issue

3

eissn

0196-0709

issn

1532-818X

pii

S0196-0709(01)69170-1

journal_volume

22

pub_type

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