Abstract:
:Intense sounds were delivered to 11 subjects with normal hearing both before and during administration of standard doses of four nonsteroidal anti-inflammatory drugs. After four days of aspirin treatment (3.9 g daily), the subjects' resting hearing levels raised by about 10 dB. Administration of intense sounds that had previously been shown to produce about 12 dB of temporary hearing loss added increments of 10 to 15 dB to the aspirin-induced hearing loss. That is, the total temporary hearing loss produced by aspirin plus exposure to intense sound was about 10 to 15 dB greater than that produced by exposure to the intense sound alone. A similar effect was observed for sodium salicylate. After similar administrations of sulindac (400 mg per day) and diflunisal (750 mg per day), there was no corresponding increase in the sound-induced hearing loss. Under certain reasonable assumptions about underlying mechanisms, these findings suggest that persons taking moderate doses of aspirin or sodium salicylate may be at increased risk of noise-induced hearing loss.
journal_name
Am J Otolaryngoljournal_title
American journal of otolaryngologyauthors
McFadden D,Plattsmier HS,Pasanen EGdoi
10.1016/s0196-0709(84)80033-2subject
Has Abstractpub_date
1984-07-01 00:00:00pages
235-41issue
4eissn
0196-0709issn
1532-818Xpii
S0196-0709(84)80033-2journal_volume
5pub_type
杂志文章abstract:PURPOSE:To evaluate the efficacy of the neoadjuvant chemotherapy and radiation therapy in treatment of patients with advanced hypopharyngeal cancer, which is notorious for its poor prognosis and severe surgical morbidity with functional deficits. MATERIALS AND METHODS:Medical records of 62 patients with squamous cell ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(98)90064-3
更新日期:1998-01-01 00:00:00
abstract::A 37-year old man had laryngeal myxoma arising from the lingual surface of the epiglottis. Laryngeal myxoma appears to be rare, as the authors' review of the literature failed to reveal any cases reported in the past two decades. ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(86)80036-9
更新日期:1986-01-01 00:00:00
abstract::It is imperative that surgeons should have some knowledge and understanding of the beliefs of Jehovah's Witnesses to respect the patient's wishes and effectively minimize and manage blood loss. The objective of this review was to provide a management strategy for Jehovah's Witness patients undergoing otolaryngology, h...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/j.amjoto.2007.08.006
更新日期:2008-07-01 00:00:00
abstract:PURPOSE:Bone conduction hearing devices are a well-established treatment option for conductive or mixed hearing losses as well as single-sided deafness. The Osia® 2 System is an active osseointegrated device where a surgically implanted titanium fixture supports a newly developed piezoelectric actuator that is placed u...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102818
更新日期:2021-01-01 00:00:00
abstract::This article reviews the functions of the enzyme Na+,K+-ATPase in epithelial tissues and discusses early and recent biochemical, physiologic and morphologic studies of the enzyme in the inner ear. The purpose of the investigation was to learn whether a relationship between perturbations in activity of the enzyme and M...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(82)80010-0
更新日期:1982-09-01 00:00:00
abstract:BACKGROUND:Primary non-Hodgkin lymphomas (NHLs) of the sinonasal tract comprise a rare entity that constitutes 1.5% of all NHLs and 2.2% of extranodal lymphomas in the whites. Clinical diagnosis may be very challenging because of the variety and low specificity of the presenting symptoms and signs. METHODS-RESULTS:We ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2005.09.019
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:The clinical use of aminoglycoside antibiotics is limited in most countries because of auditory toxicity side effects. However, their use is common in developing countries because they are inexpensive and convenient. Salvia miltiorrhiza extracts are used clinically in China for their antioxidant properties. W...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2013.08.022
更新日期:2014-03-01 00:00:00
abstract::Recent technological advances and developments in surgical technique have made the craniocervical junction (CCJ) accessible through the transnasal surgical corridor. Endoscopic endonasal transclival and transodontoid approaches have been previously described in the literature. Traditionally, these approaches entail a ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2014.12.005
更新日期:2015-05-01 00:00:00
abstract::The delivery of nutrients to the tissues and the removal of waste products from the tissues is made possible by forcing a stream of blood through an arborizing network of microscopic blood vessels that comprise the microcirculation. The rapidity of the flow stream and, therefore, the rate of nutrient delivery to the t...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/s0196-0709(88)80035-8
更新日期:1988-11-01 00:00:00
abstract::Ectopic thyroid is a rare developmental anomaly. It can be found anywhere between the foramen cecum and the normal position of the thyroid gland. Massive bleeding from an ectopic lingual thyroid is unusual and occasionally fatal. We present a case of a 22-year-old woman who had a large mass at the base of the tongue f...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1053/ajot.2002.123432
更新日期:2002-05-01 00:00:00
abstract:PURPOSE:Conflicting locations of the spinal accessory nerve (SAN) with respect to the internal jugular vein (IJV) are reported in the literature and anatomy texts. The objective of this study is to analyze this anatomic relationship specifically at the level of the posterior belly of the digastric muscle where it is en...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2013.05.008
更新日期:2013-09-01 00:00:00
abstract:PURPOSE:Our study goal was to identify clinical factors associated with, and that might predict, treatment outcome for patients with an isolated cervical recurrence of squamous cell carcinoma in the previously treated neck (ICR-PTN). MATERIALS AND METHODS:We reviewed all patients with noncutaneous head and neck squamo...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1053/ajot.2000.18871
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:The receptor activator for nuclear factor-κB ligand (RANKL) and osteoprotegerin (OPG) are the key factors controlling the osteoclast and osteoblast action in the bone. PURPOSE:The study objective was to investigate the expression level of RANKL and OPG in cholesteatoma and granulation tissue, and to assess ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2009.06.004
更新日期:2010-11-01 00:00:00
abstract::Primary middle ear neoplasms are rare, and commonly cause conductive hearing loss. When aural masses result in sensorineural hearing loss, malignant etiologies are often suspected. Fibroepithelial polyps are benign lesions commonly found in the skin and genitourinary tract and are not commonly identified as primary le...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2015.01.021
更新日期:2015-05-01 00:00:00
abstract:PURPOSE:The aim of the study was to present a consecutive series of neonatal dacryocele with endonasal cyst diagnosed and treated in our institution and to compare our management regimen and outcome with those reported in the literature. METHODS:The study was conducted at a university-affiliated teaching hospital. Stu...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2009.11.009
更新日期:2011-03-01 00:00:00
abstract:INTRODUCTION:Sir Charles Bell is renowned and revered as an outstanding surgeon, anatomist, clinician and teacher and his many contributions to various medical fields have been amply described. What are less well-known are his contributions to the field of laryngology. METHODS:Selected clinical and physiological publi...
journal_title:American journal of otolaryngology
pub_type: 传,历史文章,杂志文章,评审
doi:10.1016/j.amjoto.2017.04.011
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:Several methods have been reported for inferior turbinate (IT) reduction. We describe office-based interstitial IT reduction using bipolar cautery and evaluate long-term efficacy. METHODS:Sixty patients with allergic and nonallergic rhinitis unresponsive to medical treatment underwent office IT reduction be...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102449
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of adding platelet rich plasma (PRP) or Hyaluronic acid (HA) to fat graft myringoplasty (FGM) for medium sized central tympanic membrane (TM) perforations. METHODS:This is a retrospective study conducted on 69 patients with medium sized central TM perforations. In 21 patients, PRP was...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2018.08.004
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:The aim of the study was to evaluate the efficacy of low-dose dexamethasone sodium phosphate (5 mg) on the prophylaxis of nausea and vomiting after tympanomastoid surgery. Tropisetron hydrochloride (2 mg) and saline were used as controls. MATERIALS AND METHODS:One hundred twenty patients (n = 40 in each of 3 g...
journal_title:American journal of otolaryngology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1053/ajot.2002.126319
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVES:Analyze postoperative complications after free flap surgery based on PGY training level. METHODS:Data on free flap surgeries of the head and neck performed from 2005 to 2013 was collected from the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database. Cases identifying ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2017.06.001
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:We aimed to evaluate the possible changes in the middle ears of patients with rheumatoid arthritis (RA) and to measure their hearing functions by eleven different test frequencies including standard and high frequencies. MATERIALS AND METHODS:The study group was comprised of 74 patients with RA. The control gr...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2004.06.001
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:CT temporal bone scans are often performed to aid in surgical planning and management of cholesteatomas. With improvements in the resolution of CT scans today, it is now possible to obtain more information from these scans than before. The aim of this study is to compare findings on high resolution CT (HRCT) ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.amjoto.2014.02.015
更新日期:2014-07-01 00:00:00
abstract:PURPOSE:This study was developed to test the hypothesis that intensive biofeedback and relaxation training may favorably affect chronic tinnitus. PATIENTS AND METHODS:Seven subjects with chronic tinnitus of moderate to severe intensity engaged in an intensive 5-month program of weekly, individual 90 minute sessions. A...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/0196-0709(92)90075-5
更新日期:1992-11-01 00:00:00
abstract:PURPOSE:A case-control study was done to confirm the higher prevalence of sensorineural hearing loss (SNHL) among sickle cell patients (HbSS) from southern Brazil. PATIENTS AND METHODS:Twenty-eight patients and 28 matched normal controls were studied. Besides complete anamneses and physical otolaryngological examinati...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(00)85001-2
更新日期:2000-03-01 00:00:00
abstract::Zygomatic hemangioma is an extremely rare, benign, slow-growing tumor occurring mostly in adult women. The radiologic findings are diagnostic. Total excision of the tumor with primary reconstruction of the defect is the preferred treatment modality. We present a case of zygomatic hemangioma and a brief review of the l...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/s0196-0709(02)32429-3
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the vestibular functions and dual-task performances of individuals with noise induced hearing loss. MATERIALS AND METHODS:Fifty individuals with noise induced hearing loss and 25 healthy individuals were included in the study. Individuals with noise induced hearing loss we...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102665
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:The endoscopic brow lift technique relies on brow mobilization and often soft fixation to the underlying calvarium. While the endoscopic brow lift has been used safely, there are anecdotal reports of cerebrospinal fluid leak. We sought to measure calvarial thickness to improve the safety of cranial fixatio...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2013.03.014
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:The main limitation of fine-needle aspiration (FNA) is its limited distinction between neoplastic and benign lesions. We summarize our experience with thyroid nodules that were defined as follicular lesions by comparing the clinical and cytological features of the thyroid follicular lesions that were examine...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(03)00030-9
更新日期:2003-07-01 00:00:00
abstract:PURPOSE:To determine the role of endoscopic surgery in decreasing intraoperative bleeding, morbidity, and hospitalization period of juvenile nasopharyngeal angiofibroma resection and to describe combined endoscopic transnasal and transoral approaches. PATIENTS AND METHODS:Twelve cases of juvenile nasopharyngeal angiof...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(02)32402-5
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:To investigate the combined use of a nanocarbon (NC) suspension and low-dose 99mTc-MIBI for parathyroid localization during surgery in patients with secondary hyperparathyroidism (sHPT). METHODS:Between March 2010 and September 2015, 40 patients with sHPT were enrolled in this study and were randomized to re...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.amjoto.2017.12.008
更新日期:2018-01-01 00:00:00