Abstract:
OBJECTIVE:To investigate the combined use of a nanocarbon (NC) suspension and low-dose 99mTc-MIBI for parathyroid localization during surgery in patients with secondary hyperparathyroidism (sHPT). METHODS:Between March 2010 and September 2015, 40 patients with sHPT were enrolled in this study and were randomized to receive either low-dose 99mTc-MIBI+NC (group I) or low-dose 99mTc-MIBI (group II). Pre- and post-operative serum levels of intact PTH (iPTH), calcium and phosphorus between groups were compared and the intra-operative radioactive counts of the parathyroid glands were measured. RESULTS:The post-operative iPTH level was significantly lower in patients of group I (24.2±31ng/L) than in those of group II (106±155ng/L) (P=0.03) while there were no significant differences in intra-operative parathyroid gland radioactive counts between the groups. The duration of the surgical procedure was shorter for patients of group I than patients of group II. There were no serious intra-operative or post-operative complications. CONCLUSION:The combined use of an NC suspension and 99mTc-MIBI for patients with sHPT is strongly recommended for the localization of parathyroid glands during surgery and is likely to improve clinical outcomes for patients.
journal_name
Am J Otolaryngoljournal_title
American journal of otolaryngologyauthors
Chen J,Zhou Q,Feng J,Wang Jdoi
10.1016/j.amjoto.2017.12.008subject
Has Abstractpub_date
2018-01-01 00:00:00pages
138-141issue
2eissn
0196-0709issn
1532-818Xpii
S0196-0709(17)30670-1journal_volume
39pub_type
杂志文章,随机对照试验abstract::Aminoglycoside antibiotics are frequently employed in the treatment of serious infections caused by aerobic gram negative bacilli. The use of these potent antibacterial agents is limited by the risks of ototoxicity and nephrotoxicity. Aminoglycosides are excreted by glomerular filtration at a rate proportional to the ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
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abstract:OBJECTIVE:This study was designed for better understanding of the role of different methods of nasal endoscopy in the assessment of adenoid hypertrophy and comparing them with lateral neck radiography and patients' symptoms. SUBJECTS AND METHOD:From August 2007 until January 2009, in the otolaryngology ward of a terti...
journal_title:American journal of otolaryngology
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abstract:PURPOSE:Auditory neuropathy is characterized by congenital sensorineural hearing loss associated with absent or impaired auditory brainstem evoked responses and preservation of outer hair cell activity. This study describes the recent experience of our tertiary pediatric center with auditory neuropathy (AN). METHODS:T...
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journal_title:American journal of otolaryngology
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abstract::Pyriform sinus fistula is a rare branchial anomaly that manifests as recurrent cervical infection resulting from contamination of the fistula internal orifice in the pyriform sinus. Although open neck surgery to resect the fistula has been recommended as a definitive treatment, identifying the fistula within the scar ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
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更新日期:2015-07-01 00:00:00
abstract:PURPOSE:Determine the clinical efficacy of comprehensive neurotologic testing in patients presenting with complaints of hearing loss, tinnitus and/or dizziness. METHODS:This is a retrospective analysis of 1170 consecutive charts of patients who presented between 1980 and 2013 with neurotologic complaints. Demographic ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2018.09.009
更新日期:2019-01-01 00:00:00
abstract::Opioid analgesics play an important part in the interdisciplinary management of head and neck cancer patients. Acute pain during the initial treatment period and chronic pain after treatment may be undertreated by head and neck surgeons because of unwarranted fear of the opioid side effects and toxicities. Properly us...
journal_title:American journal of otolaryngology
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journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2017.03.009
更新日期:2017-01-01 00:00:00
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journal_title:American journal of otolaryngology
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journal_title:American journal of otolaryngology
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更新日期:2006-05-01 00:00:00
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journal_title:American journal of otolaryngology
pub_type: 杂志文章
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更新日期:2020-01-01 00:00:00
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journal_title:American journal of otolaryngology
pub_type: 杂志文章
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journal_title:American journal of otolaryngology
pub_type: 杂志文章
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更新日期:2020-01-01 00:00:00
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journal_title:American journal of otolaryngology
pub_type: 杂志文章
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更新日期:2012-05-01 00:00:00
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journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2018.12.012
更新日期:2019-01-01 00:00:00
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journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2008.05.003
更新日期:2009-07-01 00:00:00
abstract:PURPOSE:Our study goal was to identify clinical factors associated with, and that might predict, treatment outcome for patients with an isolated cervical recurrence of squamous cell carcinoma in the previously treated neck (ICR-PTN). MATERIALS AND METHODS:We reviewed all patients with noncutaneous head and neck squamo...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1053/ajot.2000.18871
更新日期:2000-11-01 00:00:00
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pub_type: 杂志文章
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journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2012.05.009
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journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
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journal_title:American journal of otolaryngology
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doi:10.1053/ajot.2001.28071
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journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/0196-0709(95)90006-3
更新日期:1995-01-01 00:00:00
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journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2009.11.009
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:Few studies in the past decade have focused on antimicrobial resistance of bacteria in pediatric rhinosinusitis. This study aimed to characterize organisms cultured from pediatric chronic rhinosinusitis, as well as current resistance patterns of pathogens. MATERIALS AND METHODS:The study was conducted from Jan...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2008.11.014
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:The aim of this article is to present the development of brown tumors in the jaws as a definite feature of hyperparathyroidism (HPT), whether primary or secondary. PATIENTS AND METHODS:The study included 2 cases of primary HPT and 3 cases of secondary HPT associated with brown tumors in the jaws. The patients ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/j.amjoto.2005.11.004
更新日期:2006-07-01 00:00:00
abstract:PURPOSE:Due to the COVID-19 pandemic, aerosol-generating procedures (AGPs) such as flexible endoscopic evaluation of swallowing (FEES) have been deemed high-risk and in some cases restricted, indicating the need for additional personal protective equipment. The aim of this study was to erect and study a protective barr...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102888
更新日期:2021-01-04 00:00:00
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更新日期:2021-01-01 00:00:00
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journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2012.08.005
更新日期:2013-01-01 00:00:00
abstract::Intralabyrinthine schwannomas are rare tumors of the distal ends of the cochlear and vestibular nerve. Their presence can be debilitating secondary to symptoms of hearing loss, vertigo, tinnitus, and imbalance. Currently, treatment to restore hearing in those who have become profoundly deaf is not attempted. Additiona...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2013.11.002
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:A murine model of squamous cell carcinoma (SCC) was used to determine the role of arachidonic acid (AA) metabolites in the growth of SCC of the head and neck. MATERIALS AND METHODS:C3H/HeJ mice bearing SCC (SCC VII) were treated with cyclooxygenase inhibitors (piroxicam and nabumetone) or a 5-lipoxygenase inhi...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(97)90041-7
更新日期:1997-01-01 00:00:00