Immunisation of a cohort Pacific children living in New Zealand over the first 2 years of life.

abstract：:The combined sheep pox and Peste des Petits ruminants (PPR) vaccine was prepared in lyophilized form containing recommended doses of both vaccine viruses. Safety and immunogenicity of this combined vaccine was evaluated in sheep. Sheep immunized subcutaneously with 1ml of live attenuated vaccine consisting of 10(3)TCI...

journal_title：Vaccine

authors： Chaudhary SS,Pandey KD,Singh RP,Verma PC,Gupta PK

更新日期：2009-04-28 00:00:00

abstract：:Mathematical models of HPV vaccine effectiveness and cost-effectiveness have produced conflicting results. The aim of this study was to use mathematical models to compare and isolate the impact of the assumptions most commonly made when modeling the effectiveness of HPV vaccines. Our results clearly show that differen...

journal_title：Vaccine

authors： Van de Velde N,Brisson M,Boily MC

更新日期：2010-07-26 00:00:00

abstract：:Parainfluenza virus type 1 (PIV1) is a major cause of croup in infants and young children, and a vaccine is needed to prevent the serious disease caused by this virus. In the present study, a live attenuated PIV1 vaccine candidate was generated by modification of the extensively-studied PIV3 cold-passaged (cp) cp45 va...

journal_title：Vaccine

authors： Skiadopoulos MH,Tao T,Surman SR,Collins PL,Murphy BR

更新日期：1999-10-14 00:00:00

abstract：UNLABELLED:Due to the high burden of pneumonia in Indonesia, the inclusion of pneumococcal conjugate vaccine (PCV) into Indonesia's National Immunization Program (NIP) is recommended by World Health Organization. Prior to the introduction of new vaccines, it is imperative to assess the perceptions of the public and med...

journal_title：Vaccine

authors： Harjaningrum AT,Kartasasmita C,Orne-Gliemann J,Jutand MA,Goujon N,Koeck JL

更新日期：2013-03-01 00:00:00

abstract：:We have shown previously that expression library immunization is viable alternative approach to induce protective immunity against Neisseria meningitidis serogroup B. In this study we report that few rounds of library screening allow identification of protective pools of defined antigens. A previously reported protect...

journal_title：Vaccine

authors： Yero D,Pajón R,Pérez Y,Fariñas M,Cobas K,Diaz D,Solis RL,Acosta A,Brookes C,Taylor S,Gorringe A

更新日期：2007-07-09 00:00:00

abstract：BACKGROUND:As part of the U.S. Department of Health and Human Services (HHS) Pandemic Influenza Plan preparedness and response strategy, the National Pre-Pandemic Influenza Vaccine Stockpile (NPIVS) program was established by the Biomedical Advanced Research and Development Authority (BARDA) in 2005 with the goal of bu...

journal_title：Vaccine

authors： Oshansky CM,Zhou J,Gao Y,Schweinle JE,Biscardi K,DeBeauchamp J,Pavetto C,Wollish A,BRITE Study Coordination Team.,Webby RJ,Cioce V,Donis RO,Bright RA

更新日期：2019-01-14 00:00:00

abstract：:Using a fixed dose of antigen, the immune response to detoxified mutants of LT-WT following intranasal (i.n.), subcutaneous (s.c.) and oral (i.g.) immunisation has been studied. When given i.n., both LT-WT and mutant toxin, K63, generated significant levels of toxin-specific IgG in the serum, and the levels of IgA in ...

journal_title：Vaccine

authors： Douce G,Giuliani MM,Giannelli V,Pizza MG,Rappuoli R,Dougan G

更新日期：1998-07-01 00:00:00

abstract：:Defective interfering (DI) virus RNAs result from major deletions in full-length viral RNAs that occur spontaneously during de novo RNA synthesis. These RNAs are packaged into virions that are by definition non-infectious, and are delivered to cells normally targeted by the virion. DI RNAs can only replicate with the ...

journal_title：Vaccine

authors： Mann A,Marriott AC,Balasingam S,Lambkin R,Oxford JS,Dimmock NJ

更新日期：2006-05-15 00:00:00

abstract：:Plasmodium vivax is responsible for an approximate 35 million yearly human cases of malaria. Unfortunately, due to the low mortality rate associated with it and the difficulties of continuously in vitro culturing of this parasite, vaccine development against this human malaria has been largely neglected. In here, the ...

journal_title：Vaccine

authors： de Oliveira CI,Wunderlich G,Levitus G,Soares IS,Rodrigues MM,Tsuji M,del Portillo HA

更新日期：1999-08-06 00:00:00

abstract：BACKGROUND:Few studies report the effectiveness of trivalent inactivated influenza vaccine (TIV) in preventing hospitalisation for influenza-confirmed respiratory infections. Using a prospective surveillance platform, this study reports the first such estimate from a well-defined ethnically diverse population in New Ze...

journal_title：Vaccine

authors： Turner N,Pierse N,Bissielo A,Huang QS,Baker MG,Widdowson MA,Kelly H,SHIVERS investigation team.

更新日期：2014-06-17 00:00:00

abstract：:Three proteins of PE and PPE families of Mycobacterium tuberculosis were evaluated for their ability to induce T cell responses in mice. To enhance immunity induced by protein immunization, we tested the efficacy of adjuvant Ribi (monophosphoryl lipid A+TDM), along with three proteins of the PE/PPE family. Balb/c mice...

journal_title：Vaccine

authors： Chaitra MG,Nayak R,Shaila MS

更新日期：2007-10-10 00:00:00

abstract：:The conventional egg-grown influenza vaccines are trivalent. To test the feasibility of using multivalent influenza virus-like particles (VLPs) as an alternative influenza vaccine, we developed cell-derived influenza VLPs containing the hemagglutinin (HA) of the H1 subtype virus A/PR/8/34 or the H3 subtype virus A/Aic...

journal_title：Vaccine

authors： Quan FS,Steinhauer D,Huang C,Ross TM,Compans RW,Kang SM

更新日期：2008-06-19 00:00:00

abstract：:We have just witnessed the largest and most devastating outbreak of Ebola virus disease, which highlighted the urgent need for development of an efficacious vaccine that could be used to curtail future outbreaks. Prior to 2014, there had been limited impetus worldwide to develop a vaccine since the virus was first dis...

journal_title：Vaccine

authors： Venkatraman N,Silman D,Folegatti PM,Hill AVS

更新日期：2018-08-28 00:00:00

abstract：:A bovine herpesvirus 4 was isolated from the milk cell fraction of a healthy cow and his full genome cloned as a bacterial artificial chromosome. So cloned viral genome was used as a vector platform to deliver in vitro and in vivo an optimized secreted chimeric peptide obtained by the fusion of the bovine viral diarrh...

journal_title：Vaccine

authors： Donofrio G,Sartori C,Franceschi V,Capocefalo A,Cavirani S,Taddei S,Flammini CF

更新日期：2008-11-11 00:00:00

abstract：:During the 2000/2001 influenza season in Japan, children ranging in age from 6 months to 13 years with fever exceeding 37.5 degrees C were recruited. Vaccine efficacy was evaluated by comparing the rates of pre-seasonal vaccination between groups stratified by fever severity. Seven hundred and sixty one patients (33.1...

journal_title：Vaccine

authors： Kamada M,Nagai T,Kumagai T,Igarashi M,Ihara T,Okafuji T,Ochiai H,Sakiyama H,Shimomura K,Suzuki E,Torigoe S,Miyazaki C,Miyata A,Yuri K,Ito Y,Nakayama T,Kase T,Okuno Y

更新日期：2006-04-24 00:00:00

abstract：:The ability of monophosphoryl lipid A (MPL), QS-21 and alum to alter the immunologic response to immunization with respiratory syncytial virus a chimeric FG construct (FG) subunit vaccine was examined in BALB/c mice. FG/MPL, FG/alum, and FG/MPL/QS-21 combinations increased non-neutralizing antibody response, while FG/...

journal_title：Vaccine

authors： Neuzil KM,Johnson JE,Tang YW,Prieels JP,Slaoui M,Gar N,Graham BS

更新日期：1997-04-01 00:00:00

abstract：:SOCS1-1 is crucial for control of immune cell cytokine expression, including those cytokines known to enable memory T-cell formation and homeostasis. In this study, we found that immunization with SOCS1-downregulated bone marrow-derived dendritic cells generated increased antigen-specific CD8(+) T memory cells and ant...

journal_title：Vaccine

authors： Aldrich M,Sanders D,Lapteva N,Huang XF,Chen SY

更新日期：2008-02-20 00:00:00

abstract：:Intranasal (i.n.) immunization of BALB/c mice with chimeric murine rotavirus EDIM (epizootic diarrhea of infant mice) VP6 and attenuated E. coli heat-labile toxin (LT), LT(R192G), stimulated >99% protection against rotavirus shedding after EDIM challenge. Here, we evaluated other potential adjuvants with chimeric VP6 ...

journal_title：Vaccine

authors： Choi AH,McNeal MM,Flint JA,Basu M,Lycke NY,Clements JD,Bean JA,Davis HL,McCluskie MJ,VanCott JL,Ward RL

更新日期：2002-03-15 00:00:00

abstract：:Our development of genetic immunization (unfortunately named 'DNA'-immunization at times) seems to have great promise as a vaccine delivery system. However, one is still left with the often formidable problem of discovering what gene of the pathogen to include in the genetic immunization vector. The is particularly a ...

journal_title：Vaccine

authors： Johnston SA,Barry MA

更新日期：1997-06-01 00:00:00

abstract：:To improve immune responses to influenza vaccine, a trivalent inactivated vaccine containing 60 microg of the HA of each component (A/H3N2, A/H1N1, B) was compared to a licensed vaccine containing 15 microg of the HA of each. More local and systemic reactions were reported by subjects given the high dosage but only lo...

journal_title：Vaccine

authors： Couch RB,Winokur P,Brady R,Belshe R,Chen WH,Cate TR,Sigurdardottir B,Hoeper A,Graham IL,Edelman R,He F,Nino D,Capellan J,Ruben FL

更新日期：2007-11-01 00:00:00

abstract：:The spike peplomer S1 subunit sequence from avian infectious bronchitis virus (IBV) Vic S strain was expressed in a plasmid under the control of the fowl adenovirus (FAV) major late promoter (MLP). Two recombinants were constructed in FAV serotype 8 (FAV 8) by inserting the expression cassette between the SnaBI and Xb...

journal_title：Vaccine

authors： Johnson MA,Pooley C,Ignjatovic J,Tyack SG

更新日期：2003-06-20 00:00:00

abstract：BACKGROUND:Despite being committed to the immunization agenda set by the WHO, Italy is currently experiencing decreasing vaccination rates and increasing incidence of vaccine-preventable diseases. Our aim is to analyze Italian online debates on pediatric immunizations through a content analytic approach in order to qua...

journal_title：Vaccine

authors： Fadda M,Allam A,Schulz PJ

更新日期：2015-12-16 00:00:00

abstract：:Foetal Bovine Serum (FBS) and porcine trypsin are one of the essential raw materials used in the manufacturing of cell culture based viral vaccines. Being from animal origin, these raw materials can potentially contaminate the final product by known or unknown adventitious agents. The issue is more serious in case of ...

journal_title：Vaccine

authors： Vaidya V,Dhere R,Agnihotri S,Muley R,Patil S,Pawar A

更新日期：2018-07-05 00:00:00

abstract：BACKGROUND:Measles supplementary immunization activities (SIAs) are vaccination campaigns that supplement routine vaccination programs with a recommended second dose opportunity to children of different ages regardless of their previous history of measles vaccination. They are conducted every 2-4 years and over a few w...

journal_title：Vaccine

authors： Portnoy A,Jit M,Helleringer S,Verguet S

更新日期：2018-01-02 00:00:00

abstract：:Targeting dendritic cell mannose receptors by mannosylating antigens represents a promising vaccination strategy. Using the model antigen ovalbumin (OVA) expressed recombinantly in bacterial and yeast vectors, we have previously demonstrated fungal mannosylation enhances antigen immunogenicity in the context of CD4(+)...

journal_title：Vaccine

authors： Luong M,Lam JS,Chen J,Levitz SM

更新日期：2007-05-30 00:00:00

abstract：:We have compared two types of plasmids for DNA immunization against HTLV-I envelope glycoproteins. One type of plasmid contains the coding DNA of the complete envelope gene of HTLV-I under the control of the CMV promoter with (CMVenvLTR) or without (CMVenv) the tax/rex genes. The second type contains the coding DNA of...

journal_title：Vaccine

authors： Armand MA,Grange MP,Paulin D,Desgranges C

更新日期：2000-04-28 00:00:00

abstract：:A family of parasite antigens known as Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is believed to play an important role in the binding of infected erythrocytes to host receptors in the micro-vasculature. Available data advocates the existence of a subset of very adhesive (rosetting, auto-agglutinati...

journal_title：Vaccine

authors： Chen Q,Pettersson F,Vogt AM,Schmidt B,Ahuja S,Liljeström P,Wahlgren M

更新日期：2004-07-29 00:00:00

abstract：:A phase II safety and immunogenicity study of an oral-formalin inactivated enterotoxigenic Escherichia coli (ETEC) vaccine containing six colonization factors (CFA/I, CS1, CS2, CS3, CS4, CS5) and 1mg of recombinant cholera toxin B subunit (the CF-BS-ETEC vaccine) was carried out in an urban slum of Dhaka city in Bangl...

journal_title：Vaccine

authors： Qadri F,Ahmed T,Ahmed F,Bradley Sack R,Sack DA,Svennerholm AM

更新日期：2003-06-02 00:00:00

abstract：:The ability of ALVAC- or fowlpox-based simian immunodeficiency virus (SIV) vaccines to boost SIV-specific CD4+ and CD8+ T-cell responses was tested in 10 vaccinia-experienced macaques infected with SIVmac251. The CD8+ T-cell response to the dominant Gag(181-189) CM9 was quantitated in seven Mamu-A*01-positive macaques...

journal_title：Vaccine

authors： Nacsa J,Radaelli A,Edghill-Smith Y,Venzon D,Tsai WP,Morghen Cde G,Panicali D,Tartaglia J,Franchini G

更新日期：2004-01-26 00:00:00

abstract：:Information provided by most influenza vaccine manufacturers do not reflect the recommendations of WHO and/or national public health advisory groups with regard to the use of influenza vaccines in pregnant or lactating women. The majority of vaccines contain precautionary language which could discourage use in pregnan...

journal_title：Vaccine

authors： Proveaux T,Lambach P,Ortiz JR,Hombach J,Halsey NA

更新日期：2016-10-26 00:00:00