Functional assessment of immune markers of graft rejection: a comprehensive study in live-related donor renal transplantation.

abstract：:The number of nonrenal solid-organ transplants increased substantially in the last few decades. Many of these patients develop renal failure and receive kidney transplantation. The aim of this study was to evaluate patient and kidney allograft survival in primary, repeat, and kidney-after-nonrenal organ transplantatio...

journal_title：Clinical transplantation

authors： El-Husseini A,Aghil A,Ramirez J,Sawaya B,Rajagopalan N,Baz M,Mei X,Davenport DL,Gedaly R

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:The benefits of pancreas transplantation are often difficult to measure. Here, we sought to determine the difference in quality of life for diabetic patients with and without a functional pancreas transplant alone (PTA). METHODS:Pancreas transplant alone cases from 1993 to 2015 were considered. An IRB-appro...

journal_title：Clinical transplantation

authors： Scalea JR,Pettinato L,Fiscella B,Bartosic A,Piedmonte A,Paran J,Todi N,Siskind EJ,Bartlett ST

更新日期：2018-02-01 00:00:00

abstract：:Endoscopy with histopathological assessment is an established practice to confirm gastrointestinal graft-versus-host disease (GI-GVHD). However, the clinical relevance of this approach in children is incompletely evaluated. In a retrospective cohort study, we investigated the frequency of treatment changes in response...

journal_title：Clinical transplantation

authors： Mårtensson T,Mellgren K,Toporski J,Arvidson J,Szakos A,Casswall TH,Gustafsson B

更新日期：2020-07-01 00:00:00

abstract：:The practice of uncontrolled donation after cardiac death (uDCD) has been met with tepid interest within the United States transplant community. Hesitancy stems largely from fears of eroding public trust due to complex ethical issues involving consent. Beyond ethical concerns, uDCD creates unique logistic challenges t...

journal_title：Clinical transplantation

authors： Choudhury RA,Prins K,Moore HB,Yoeli D,Kam A,Nydam TL

更新日期：2019-03-01 00:00:00

abstract：:Whole pancreas and islet cell transplantation are both reliant upon the procurement and preservation of a high quality donor pancreas for a successful outcome. In the climate of a reducing donor pool it is imperative that donor optimization, meticulous surgical retrieval and evidence based methods of preservation are ...

journal_title：Clinical transplantation

authors： Ridgway D,Manas D,Shaw J,White S

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Invasive fungal infections (IFI) are associated with significant morbidity and mortality in lung transplant recipients (LTRs). However, data outlining use of echinocandins in prophylaxis and therapy of LTRs are limited. METHOD:A single-center retrospective cohort study on all LTRs from January-2010 to Decem...

journal_title：Clinical transplantation

authors： Al Jishi Y,Rotstein C,Kumar D,Humar A,Singer LG,Keshavjee S,Husain S

更新日期：2018-12-01 00:00:00

abstract：:Daclizumab (DAC) is a molecularly engineered humanized IgGa monoclonal Ab directed against the alpha chain of the interleukin-2 receptor (IL2R). Inhibiting the amplification of the immune response by blocking IL2R can reduce the frequency of acute rejection without the attendant risk of infection. The purpose of this ...

journal_title：Clinical transplantation

authors： Rasaiah SB,Light JA,Sasaki TM,Currier CB

更新日期：2000-08-01 00:00:00

abstract：:Aboriginals experience high rates of end-stage renal disease (ESRD) and are less likely to receive a kidney transplant from a living donor. We hypothesized that higher rates of hypertension and diabetes in Aboriginal communities would result in fewer potential living donors coming forward and more exclusions for medic...

journal_title：Clinical transplantation

authors： Dunsmore S,Karpinski M,Young A,Storsley L

更新日期：2011-11-01 00:00:00

abstract：:Flow cytometry crossmatch (FCXM) is a more sensitive technique than classical complement-dependent cytotoxicity (CDC) for the detection of donor-directed antibody before renal transplantation. Nevertheless, the role of FCXM in predicting long-term survival of kidney grafts is still unclear. The purpose of our study wa...

journal_title：Clinical transplantation

authors： Rebibou JM,Bittencourt MC,Saint-Hillier Y,Chabod J,Dupont I,Bittard H,Chalopin JM,Hervé P,Tiberghien P

更新日期：2004-10-01 00:00:00

abstract：:Kidney outcomes in early post-liver transplantation (LT) are crucial for long-term prognosis, but difficult to predict. Among 203 adult LT patients, we studied the value of plasma neutrophil gelatinase-associated lipocalin (NGAL) measured pre-LT for predicting acute kidney injury (AKI), kidney-replacement therapy with...

journal_title：Clinical transplantation

authors： Aberg F,Lempinen M,Hollmén M,Nordin A,Mäkisalo H,Isoniemi H

更新日期：2014-08-01 00:00:00

abstract：:Vascular complications remain a significant source of morbidity after pancreatic transplantation. We describe a pseudoaneurysm of the superior mesenteric artery (SMA) with an arteriovenous fistula (AVF) involving the SMA and the superior mesenteric vein (SMV) discovered and treated surgically in the second week after ...

journal_title：Clinical transplantation

authors： Khan TF,Ciancio G,Burke GW 3rd,Sfakianakis GN,Miller J

更新日期：1999-06-01 00:00:00

abstract：:Sauropus androgymus (SA), a vegetable of the Euphorbiaceae family, is a common food source in Malaysia. In Taiwan, over 30 patients have developed progressive respiratory failure after consuming the extract from raw SA leaves as a means of losing weight. Symptoms consistent with a severe obstructive ventilatory defect...

journal_title：Clinical transplantation

authors： Luh SP,Lee YC,Chang YL,Wu HD,Kuo SH,Chu SH

更新日期：1999-12-01 00:00:00

abstract：:Acute renal failure (ARF) is a common and severe complication after liver transplantation (LT). The aim of this study was to ascertain the impact of ARF requiring dialysis in the outcome of LT and to analyze the risk factors leading to this event in the early post-operative period. From October 1988 to December 1994, ...

journal_title：Clinical transplantation

authors： Bilbao I,Charco R,Balsells J,Lazaro JL,Hidalgo E,Llopart L,Murio E,Margarit C

更新日期：1998-04-01 00:00:00

abstract：:The present AST-IDCOP guidelines update information on BK polyomavirus (BKPyV) infection, replication, and disease, which impact kidney transplantation (KT), but rarely non-kidney solid organ transplantation (SOT). As pretransplant risk factors in KT donors and recipients presently do not translate into clinically val...

journal_title：Clinical transplantation

authors： Hirsch HH,Randhawa PS,AST Infectious Diseases Community of Practice.

更新日期：2019-09-01 00:00:00

abstract：:After cardiac transplant, there is often development of restrictive cardiac physiology. Little is known about the factors that contribute to this physiology and its correlation with pathology. Heart retransplantation provides a valuable opportunity to further understand this relationship. In this study, we investigate...

journal_title：Clinical transplantation

authors： Kobashigawa JA,Itagaki BK,Razi RR,Patel JK,Chai W,Kawano MA,Goldstein Z,Kittleson MM,Fishbein MC

更新日期：2013-11-01 00:00:00

abstract：:We sought to determine the incidence, risk factors, and consequences of acute rejection (AR) after conversion from a calcineurin inhibitor (CNI) to a proliferation signal inhibitor (PSI) in maintenance heart transplantation. Relevant clinical data were retrospectively obtained for 284 long-term heart transplant recipi...

journal_title：Clinical transplantation

authors： González-Vílchez F,Vázquez de Prada JA,Paniagua MJ,Almenar L,Mirabet S,Gómez-Bueno M,Díaz-Molina B,Arizón JM,Delgado J,Pérez-Villa F,Crespo-Leiro MG,Martínez-Dolz L,Roig E,Segovia J,Lambert JL,Lopez-Granados A,Escribano P

更新日期：2013-11-01 00:00:00

abstract：:Experimental models suggest that endothelin-1 (ET-1) has a significant role in the pathogenesis of cyclosporin A (CyA)-induced hypertension. However, its serum levels evaluated in different studies, including patients who received solid organ transplants, exhibited controversial results. Our study population consisted...

journal_title：Clinical transplantation

authors： Cauduro RL,Costa C,Lhulier F,Garcia RG,Cabral RD,Gonçalves LF,Manfro RC

更新日期：2005-08-01 00:00:00

abstract：AIMS:To evaluate the effect of donor liver resident mesenchymal cells, M2 macrophages on liver graft outcome after living donor liver transplantation. MATERIALS AND METHODS:Seventy donor biopsies were included in the study. Outcomes at day 3, 7, 30, and 180 postliver transplantation were assessed. Mesenchymal stem cel...

journal_title：Clinical transplantation

authors： Nigam N,Bihari C,Lal D,Rastogi A,Kumar S,Pamecha V,Kaur S,Kumar A,Sarin SK

更新日期：2018-03-01 00:00:00

abstract：INTRODUCTION:Thrombosis of the pancreas after transplantation is the most common cause of relaparotomy and resultant graft loss. There is currently no standard protocol consistently proven to prevent thrombosis following transplantation. Our objective was to determine whether our protocol of post-operative low-dose int...

journal_title：Clinical transplantation

authors： Aboalsamh G,Anderson P,Al-Abbassi A,McAlister V,Luke PP,Sener A

更新日期：2016-09-01 00:00:00

abstract：:Functioning nephron mass is a determinant of the graft function of kidney transplant recipients. The graft kidney volume and its weight have been reported to be surrogates of the nephron mass. To investigate the impact of the ratios of the surrogates to recipient body surface area (BSA) and body weight on the graft fu...

journal_title：Clinical transplantation

authors： Lee JH,Won JH,Oh CK

更新日期：2011-11-01 00:00:00

abstract：:Steroid-resistant acute rejection (SR-AR) and ductopenic rejection (DR) after liver transplantation are infrequent, but difficult to manage. We performed a retrospective review of patients with SR-AR or DR treated with sirolimus-based therapy. Since 2002, we have treated five patients with SR-AR and eight patients wit...

journal_title：Clinical transplantation

authors： Lladó L,Fabregat J,Castellote J,Ramos E,Torras J,Serrano T,Figueras J,Rafecas A

更新日期：2009-01-01 00:00:00

abstract：:A lack of research exploring post-transplant process optimization to reduce readmissions and increasing readmission rates at our center from 2009 to 2013 led to this study, aimed at assessing the effect of patient and process factors on 30-d readmission rates after kidney transplantation. This was a retrospective case...

journal_title：Clinical transplantation

authors： Covert KL,Fleming JN,Staino C,Casale JP,Boyle KM,Pilch NA,Meadows HB,Mardis CR,McGillicuddy JW,Nadig S,Bratton CF,Chavin KD,Baliga PK,Taber DJ

更新日期：2016-07-01 00:00:00

abstract：:Autoantibodies are frequently detected after liver transplantation (LT), but their role is unclear. This study was designed to address three points: autoantibody prevalence pre-LT and over time up to five yr after LT, identification of possible predictors of autoantibody formation, and correlation between autoantibodi...

journal_title：Clinical transplantation

authors： Foschi A,Zavaglia CA,Fanti D,Mazzarelli C,Perricone G,Vangeli M,Viganò R,Belli LS

更新日期：2015-02-01 00:00:00

abstract：:Post-transplant bone disease is common in solid organ recipients; however, there is limited information on their pre-transplant bone status. We aimed to compare bone mineral density (BMD) in different categories of patients with end-stage organ failure awaiting transplantation (Tx) in Norway. Overall 291 adult patient...

journal_title：Clinical transplantation

authors： Dolgos S,Hartmann A,Isaksen GA,Simonsen S,Bjørtuft Ø,Boberg KM,Bollerslev J

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder characterized by premature mortal cardiovascular complications. Liver transplantation (LT) is the only curative treatment option. In this study, the long-term clinical follow-up data of 8 patients who underwent LT with a diagnosis o...

journal_title：Clinical transplantation

authors： Gulsoy Kirnap N,Kirnap M,Bascil Tutuncu N,Moray G,Haberal M

更新日期：2019-12-01 00:00:00

abstract：:The exact mechanism of acute and chronic allograft rejection still remains unclear. The chemokine SDF-1 as mediator of allograft rejection has been under intensive investigation in liver, cardiac and bone marrow transplantation, whereas in renal transplantation, there are no reports about SDF-1 to date. This study was...

journal_title：Clinical transplantation

authors： Hoffmann U,Banas B,Krüger B,Banas M,Bergler T,Böger C,Kammerl M,Obed A,Rümmele P,Segerer S,Riegger GA,Krämer BK

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Clearance of hepatitis C virus (HCV) under antiviral therapy, including direct-acting antivirals (DAAs), has been associated with higher risk of rejection. Whether patients who are not on immunosuppression (IS) during DAA therapy are at higher risk of rejection is unknown. METHODS:Four transplant recipients...

journal_title：Clinical transplantation

authors： Campos-Varela I,Agudelo EZ,Terrault NA

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:With the growing numbers of liver transplant recipients, it is increasingly important to understand the risks of de novo malignancy after liver transplantation. AIM:To characterize the incidence of de novo malignancy after liver transplantation compared with a control non-transplant population. METHODS:We ...

journal_title：Clinical transplantation

authors： Chatrath H,Berman K,Vuppalanchi R,Slaven J,Kwo P,Tector AJ,Chalasani N,Ghabril M

更新日期：2013-07-01 00:00:00

abstract：INTRODUCTION:The average age of patients undergoing liver transplantation (LT) is consistently increasing. The aim of this case-control study is to evaluate survival and outcome of patients ≥65 yr compared to younger patients undergoing LT. MATERIALS AND METHODS:From 10/00 to 4/08 we performed 330 primary LT, 31 (9.4%...

journal_title：Clinical transplantation

authors： Montalti R,Rompianesi G,Di Benedetto F,Ballarin R,Gerring RC,Busani S,De Pietri L,De Ruvo N,Iemmolo RM,Guerrini GP,Smerieri N,Gerunda GE

更新日期：2010-09-01 00:00:00

abstract：:Flow cytometric assay (FCA) was used to detect a cytomegalovirus (CMV) specific antigen (pp65) in CMV-infected fibroblast cells and in leukocytes of kidney recipients. FCA distinguished clearly between the infected and non-infected fibroblast cells. Regarding transplant patients, the FCA was positive when the number o...

journal_title：Clinical transplantation

authors： Essa S,Pacsa AS,Al-Attiyah R,El-Shazly A,Raghupathy R,Said T

更新日期：2000-04-01 00:00:00