Outcomes of antiviral treatment in hepatitis C virus liver transplant patients off immunosuppression in the direct acting antivirals era: A case series.

abstract：BACKGROUND:With the growing numbers of liver transplant recipients, it is increasingly important to understand the risks of de novo malignancy after liver transplantation. AIM:To characterize the incidence of de novo malignancy after liver transplantation compared with a control non-transplant population. METHODS:We ...

journal_title：Clinical transplantation

authors： Chatrath H,Berman K,Vuppalanchi R,Slaven J,Kwo P,Tector AJ,Chalasani N,Ghabril M

更新日期：2013-07-01 00:00:00

abstract：BACKGROUNDS:Recurrent hepatitis C virus (HCV) infection is universal post-transplantation. Fibrosis (F) stage ≥2 at 12 months identifies patients with rapid fibrosis progression. Antiviral therapy (AVT) remains the only option to attenuate fibrosis progression. We hypothesized that CXCL10 levels can distinguish between...

journal_title：Clinical transplantation

authors： Joshi D,Carey I,Foxton M,Al-Freah M,Bruce M,Heaton N,Quaglia A,O'Grady J,Aluvihare V,Agarwal K

更新日期：2014-05-01 00:00:00

abstract：:As many as 50% of liver transplant patients suffer gastrointestinal (GI) disturbances post-transplant. Conversion from mycophenolate mofetil (MMF) to mycophenolate sodium (EC-MPS) alleviates GI symptom burden in renal transplant recipients. We employed a validated patient and physician-reported assessment to evaluate ...

journal_title：Clinical transplantation

authors： Toledo AH,Hendrix L,Buchholz V,Fisher E,Newton K,Smith C,Gerber DA

更新日期：2012-01-01 00:00:00

abstract：:Patients with severe liver disease and accompanying malnutrition may exhibit electrolyte disturbances including the magnesium balance. In 18 patients plasma magnesium (p-Mg) was determined at the start of the liver transplantation and during the anhepatic and reperfusion phases of the operation. The blood loss was 6.9...

journal_title：Clinical transplantation

authors： Skak C,Ejlersen E,Mogensen T,Winkel P,Secher NH

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:We performed a study to identify differences in the urinary microbiome associated with chronic allograft dysfunction (CAD) and compared the urinary microbiome of male and female transplant recipients with CAD. METHODS:This case-control study enrolled 67 patients within the Deterioration of Kidney Allograft ...

journal_title：Clinical transplantation

authors： Wu JF,Muthusamy A,Al-Ghalith GA,Knights D,Guo B,Wu B,Remmel RP,Schladt DP,Alegre ML,Oetting WS,Jacobson PA,Israni AK

更新日期：2018-12-01 00:00:00

abstract：:Approximately 8-11% of all organ donors are classified by Public Health Service (PHS) as increased-risk. The proportion of PHS increased-risk donors is on the rise. At the University of Washington Medical Center, in 2014, the proportion of transplants from PHS increased-risk donors was 28% of liver transplants and 23%...

journal_title：Clinical transplantation

authors： Sibulesky L,Javed I,Reyes JD,Limaye AP

更新日期：2015-09-01 00:00:00

abstract：:In view of the scarcity of organ resources available for transplantation, living donor liver transplantation (LDLT) is gaining growing importance in the treatment of chronically terminal liver diseases. In the period between December 1999 and October 2000, 47 potential living liver donors were evaluated and 24 right h...

journal_title：Clinical transplantation

authors： Walter M,Bronner E,Pascher A,Steinmüller T,Neuhaus P,Klapp BF,Danzer G

更新日期：2002-10-01 00:00:00

abstract：:A lack of research exploring post-transplant process optimization to reduce readmissions and increasing readmission rates at our center from 2009 to 2013 led to this study, aimed at assessing the effect of patient and process factors on 30-d readmission rates after kidney transplantation. This was a retrospective case...

journal_title：Clinical transplantation

authors： Covert KL,Fleming JN,Staino C,Casale JP,Boyle KM,Pilch NA,Meadows HB,Mardis CR,McGillicuddy JW,Nadig S,Bratton CF,Chavin KD,Baliga PK,Taber DJ

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Post-transplant gastrointestinal (GI) side effects can impair a patient's quality of life (QoL). This study investigates the improvement in GI side effects and related QoL changes in recipients of liver transplantation (OLT) after converting patients from mycophenolate mofetil (MMF) to enteric-coated mycophe...

journal_title：Clinical transplantation

authors： Doria C,Ramirez CB,Frank AM,Vaccino S,Fraser N,Marino IR

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Patients on organ transplant waiting lists continue to far exceed donor rates. We seek to understand the barriers preventing people in a Canadian city from donating organs for transplantation. METHODS:One thousand adults were surveyed assessing knowledge, personal involvement, and attitudes about organ dona...

journal_title：Clinical transplantation

authors： Lee E,Midodizi W,Gourishankar S

更新日期：2010-11-01 00:00:00

abstract：:These updated guidelines from the American Society of Transplantation Infectious Diseases Community of Practice address the prevention and management of Clostridium difficile infection in solid organ transplant (SOT) recipients. Clostridioides (formerly Clostridium) difficile infection (CDI) is among the most common h...

journal_title：Clinical transplantation

authors： Mullane KM,Dubberke ER,AST ID Community of Practice.

更新日期：2019-09-01 00:00:00

abstract：:Angiotensin-converting enzyme inhibitor (ACEI) has become recognized as agents that have renoprotective effects in the treatment of progressive renal diseases including post-transplant kidneys. Previously we demonstrated the safety and effectiveness of ACEI treatment on the hypertensive proteinuric post-transplant pat...

journal_title：Clinical transplantation

authors： Namba Y,Moriyama T,Kyo M,Oka K,Kokado Y,Shi Y,Imamura R,Ichimaru N,Okuyama A,Takahara S

更新日期：2004-01-01 00:00:00

abstract：:Criteria for organ acceptance in brain-dead organ donors remain inconsistent, especially when concerning pancreatic transplants. We sought to examine donor-specific predictors of pancreatic graft use and survival to better guide the selection and management of potential donors. A prospective observational study of all...

journal_title：Clinical transplantation

authors： Sally MB,Ellis MK,Hutchens M,Groat T,Swanson E,Patel MS,Niemann CU,Malinoski DJ

更新日期：2019-06-01 00:00:00

abstract：:ABO-incompatible kidney transplantation (ABO-ILKT) has been reported to have a higher rate of early complications and higher medical costs than ABO-compatible kidney transplantation (ABO-CLKT). We aimed to compare the clinical outcomes, complications, and medical costs between ABO-ILKTs and ABO-CLKTs at 2 years post-t...

journal_title：Clinical transplantation

authors： Kakuta Y,Okumi M,Unagami K,Iizuka J,Takagi T,Ishida H,Tanabe K

更新日期：2019-06-01 00:00:00

abstract：:Early measures of graft function are increasingly used to assess efficacy in clinical trials of kidney transplant immunosuppression. This study aimed to assess the variability and quality of reporting of these endpoints in contemporary trials. Data regarding renal function endpoints were extracted from 213 reports fro...

journal_title：Clinical transplantation

authors： Knight SR,Hussain S

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:In adult living-donor liver transplantation (LDLT), the assessment of the graft functional reserve is very important. We evaluated the graft functional reserve by technetium-99m-diethylenetriaminepenta-acetic acid-galactosyl-human serum albumin ((99m)Tc-GSA) liver scintigraphy. PATIENTS AND METHOD:From May ...

journal_title：Clinical transplantation

authors： Iida T,Isaji S,Yagi S,Hori T,Taniguchi K,Ohsawa I,Mizuno S,Usui M,Sakurai H,Yamagiwa K,Yamakado K,Uemoto S

更新日期：2009-03-01 00:00:00

abstract：:Accurate prognostic indicators are lacking for livers with early marginal graft function, making the decision to re-transplant a difficult one. Therefore, we studied 99mTc-labeled DISIDA scanning as a predictor of recovery of marginal grafts. Records of 28 liver transplant recipients with prolonged periods of marginal...

journal_title：Clinical transplantation

authors： Karademir S,Csete ME,Jurim O,Finstad T,Hawkins R,Bussuttil RW,Shaked A

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:One severe side effect of calcineurin inhibitors (CNIs: such as cyclosporine [CsA] and tacrolimus [FK506]) is neurotoxicity. CNIs are substrates for CYP3A5 and P-glycoprotein (P-gp), encoded by ABCB1 gene. In the present study, we hypothesized that genetic variability in CYP3A5 and ABCB1 genes may be associa...

journal_title：Clinical transplantation

authors： Yanagimachi M,Naruto T,Tanoshima R,Kato H,Yokosuka T,Kajiwara R,Fujii H,Tanaka F,Goto H,Yagihashi T,Kosaki K,Yokota S

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:The therapeutic drug monitoring of mycophenolic acid (MPA) has been investigated for renal and heart transplantations; however, its usefulness in lung transplantation is unclear. METHODS:The MPA area under the plasma concentration-time curve (AUC) was calculated in 59 adult lung transplant recipients. The M...

journal_title：Clinical transplantation

authors： Yabuki H,Matsuda Y,Watanabe T,Eba S,Hoshi F,Hirama T,Oishi H,Sado T,Noda M,Sakurada A,Kikuchi M,Yamaguchi H,Mano N,Okada Y

更新日期：2020-12-01 00:00:00

abstract：:The morphological characteristics of a kidney biopsy specimen taken 1 h after reperfusion of blood into the graft (1-h biopsy) during a cadaveric transplant operation were studied. The aim of the 1-h biopsy is to evaluate the pre-transplant risk factors for the delayed graft function, assess the renal function of the ...

journal_title：Clinical transplantation

authors： Oda A,Morozumi K,Uchida K

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Abnormalities of renal function with long-term implications can persist after acute tubular necrosis (ATN), probably because of permanent loss of nephrons. Residual areas of fibrosis are also observed in the renal cortex post-ATN. In this study, we investigate the interstitial alterations post-ATN using hist...

journal_title：Clinical transplantation

authors： Moyses Neto M,Costa RS,Volpini RA,Garcia TM,Rodrigues FF,Coimbra TM

更新日期：2004-04-01 00:00:00

abstract：:Although steroid avoidance and withdrawal in renal transplant recipients (RTR) are actively being evaluated by physicians, the attitudes of recipients toward steroid use have not been systematically studied in the modern era. We conducted a confidential written survey of single-organ adult RTR pertaining to prednisone...

journal_title：Clinical transplantation

authors： Prasad GV,Nash MM,McFarlane PA,Zaltzman JS

更新日期：2003-04-01 00:00:00

abstract：:The donation of organs and tissues for the benefit of another person is an altruistic act and one that is a guaranteed option for the next-of-kin through various national Required Request legislations. At the Washington Hospital Center we have developed an approach that permits organ recovery from non-heart beating do...

journal_title：Clinical transplantation

authors： Kowalski AE,Light JA,Ritchie WO,Sasaki TM,Callender CO,Gage F

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:The pediatric end stage liver disease (PELD) score has been used widely to prioritize children awaiting cadaveric liver transplantation (LTx). To establish the objective parameter for optimal timing of living-related LTx (LRLTx), we have assessed our cases using the PELD score. METHODS:From 1997 to 2002, 24...

journal_title：Clinical transplantation

authors： Kimura T,Hasegawa T,Sasaki T,Shimizu Y,Mushiake S,Fukuzawa M,Okada A

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:There have been no published data on use of the the newer immunosuppressants tacrolimus and mycophenolate mofetil (MMF) in high immunological risk renal transplantation. We therefore undertook a prospective study to systematically assess outcomes using these agents as part of an aggressive immunosuppressive ...

journal_title：Clinical transplantation

authors： Zaltzman JS,Boucher A,Busque S,Halloran PF,Landsberg DN,McAlister VC,Russell D,Shoker A,Shapiro J,Tchervenkov JI,Ferguson R

更新日期：2005-02-01 00:00:00

abstract：INTRODUCTION:A "new" fast track kidney allocation scheme (FTKAS) was implemented in the UK in 2012 for offering of previously declined kidneys. We evaluated the impact of the FTKAS in utilization of declined kidneys and outcome. METHODS:Adult renal transplant centers were surveyed. Overall utilization was evaluated us...

journal_title：Clinical transplantation

authors： White AD,Roberts H,Ecuyer C,Brady K,Pathak S,Clark B,Hostert LH,Attia MS,Wellberry-Smith M,Hudson A,Ahmad N

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:The proportion of prospective living donors disqualified for medical reasons is unknown. The objective of this study is to delineate and quantify specific reasons for exclusion of prospective living donors from kidney donation. METHODS:All adult prospective kidney donors who contacted our transplant program...

journal_title：Clinical transplantation

authors： Lapasia JB,Kong SY,Busque S,Scandling JD,Chertow GM,Tan JC

更新日期：2011-09-01 00:00:00

abstract：:Post-transplant lymphoproliferative disorders (PTLDs) are a heterogeneous set of complications of organ transplantation associated with poor patient prognosis. We analyzed the clinicopathological features of PTLDs in 43 adult and pediatric recipients of solid organ or bone marrow transplantation at a large transplant ...

journal_title：Clinical transplantation

authors： Yoon SO,Yu E,Cho YM,Suh C,Kim KM,Han DJ,Lee SG,Huh J

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Aortoiliac pathology in kidney allograft recipients is not rare but treatment timing is controversial. As most publications on this topic are case reports its difficult to evaluate long-term outcomes of those clinical challenges. Herein we report long-term results of these procedures. METHODS:From 1970 to...

journal_title：Clinical transplantation

authors： Tsivian M,Neri F,Nardo B,Bertelli R,Cavallari G,Fuga G,Faenza A

更新日期：2009-03-01 00:00:00

abstract：:Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is a cell surface protein, which down-regulates the immune response at CTLA-4/CD28/B7 pathway. We aimed to investigate the influence of the -318 C/T, +49 A/G, -1661 A/G and CT60A/G, and CTLA-4 gene polymorphisms on acute rejection of kidney allograft in Turkish patients. The s...

journal_title：Clinical transplantation

authors： Ruhi Ç,Sallakçi N,Yeğin O,Süleymanlar G,Ersoy FF

更新日期：2015-07-01 00:00:00