Psychosocial outcome of living donors after living donor liver transplantation: a pilot study.

Abstract:

:In view of the scarcity of organ resources available for transplantation, living donor liver transplantation (LDLT) is gaining growing importance in the treatment of chronically terminal liver diseases. In the period between December 1999 and October 2000, 47 potential living liver donors were evaluated and 24 right hepatic lobes and two left lateral segments were transplanted at the Virchow-Klinikum of the Charité Hospital in Berlin. The present study looks into biomedical and psychosocial parameters of 23 donors before and 6 months after LDLT. Our aims were to investigate the development of psychosocial parameters after donation and the relationship between psychosocial findings and post-operative complications. Most donors showed an improved quality of life (QoL) after LDLT when compared with pre-operative results. Twenty-six percent of donors show high values for 'tiredness', 'fatigue' and 'limb pain' following donation. The post-operative complications had no influence on the psychosocial outcome. In this pilot study the resection of the right hepatic lobe amounts to a safe operation for donors and holds promise of a good psychosocial outcome for most donors, irrespective of donation-related complications. The pronounced complaints appears to indicate psychological tension and distress in some donors following donation.

journal_name

Clin Transplant

journal_title

Clinical transplantation

authors

Walter M,Bronner E,Pascher A,Steinmüller T,Neuhaus P,Klapp BF,Danzer G

doi

10.1034/j.1399-0012.2002.02002.x

subject

Has Abstract

pub_date

2002-10-01 00:00:00

pages

339-44

issue

5

eissn

0902-0063

issn

1399-0012

pii

2o002

journal_volume

16

pub_type

杂志文章
  • New onset diabetes mellitus post-kidney transplantation.

    abstract::The study explores the prevalence of unrecognized diabetes mellitus (DM), the incidence and risk factors new onset diabetes mellitus (NODM) and determines whether patient survival differs between patients with transient (NODM that resolves) compared with those with fixed NODM. This is a single center review of solitar...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2006.00529.x

    authors: Kiberd M,Panek R,Kiberd BA

    更新日期:2006-09-01 00:00:00

  • Hyperhomocysteinemia and transplant coronary artery disease in cardiac transplant recipients.

    abstract:BACKGROUND:In cardiac transplant recipients, long-term survival may be limited by transplant coronary artery disease (TxCAD). Hyperhomocysteinemia (Hhcy) has been associated with vascular disease and is common in transplant recipients. The objective of this study was to determine the relationship between fasting homocy...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1034/j.1399-0012.2001.150407.x

    authors: Miner SE,Cole DE,Evrovski J,Verma A,Daly PA,Ross HJ

    更新日期:2001-08-01 00:00:00

  • Quality of life assessment in renal transplant: review and future directions.

    abstract::We performed a systematic search of the literature using the MEDLINE (through 2006) database to identify the patient-reported outcome measures of quality of life (QOL) used most often in the renal transplant literature. After applying limits and reviewing references, we identified 338 renal transplant articles with a ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/j.1399-0012.2007.00784.x

    authors: Butt Z,Yount SE,Caicedo JC,Abecassis MM,Cella D

    更新日期:2008-05-01 00:00:00

  • Short-term outcomes of en bloc combined heart and liver transplantation in the failing Fontan.

    abstract::Patients with failing Fontan physiology and liver cirrhosis are being considered for combined heart and liver transplantation. We performed a retrospective review of our experience with en bloc combined heart and liver transplantation in Fontan patients > 10 years old from 2006 to 18 per Institutional Review Board app...

    journal_title:Clinical transplantation

    pub_type: 临床试验,杂志文章

    doi:10.1111/ctr.13540

    authors: Vaikunth SS,Concepcion W,Daugherty T,Fowler M,Lutchman G,Maeda K,Rosenthal DN,Teuteberg J,Woo YJ,Lui GK

    更新日期:2019-06-01 00:00:00

  • Reversal of accelerated renal allograft rejection with FK 506.

    abstract::Although FK 506 has been shown to effectively reverse refractory renal allograft rejection, its ability to reverse accelerated renal allograft rejection as a primary agent has not been specifically addressed. Herein evidence of the ability of FK 506 to reverse accelerated renal allograft rejection is presented. A 16-y...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:

    authors: Woodle ES,Newell KA,Haas M,Bartosh S,Josephson MA,Millis JM,Bruce DS,Piper JB,Aronson AJ,Thistlethwaite JR

    更新日期:1997-08-01 00:00:00

  • Cutaneous cryptococcosis mimicking bacterial cellulitis in a liver transplant recipient: case report and review in solid organ transplant recipients.

    abstract::Cutaneous cryptococcosis is an uncommon manifestation of disseminated cryptococcal disease. We report a liver transplant recipient presenting with onset over 3 days of progressive pain and swelling of the lower extremity and foot with erythema and heat. Cryptococcal cellulitis was documented, but in retrospect the cli...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:

    authors: Singh N,Rihs JD,Gayowski T,Yu VL

    更新日期:1994-08-01 00:00:00

  • Interstitial expression of heat-shock protein 47 correlates with capillary deposition of complement split product C4d in chronic allograft nephropathy.

    abstract:BACKGROUND:Chronic allograft nephropathy (CAN), associated with late-allograft dysfunction is caused by alloantigen-dependent and -independent mechanisms, and eventually leads to interstitial fibrosis (ci). Activation of complement cascade is considered to be a poor prognostic marker of graft survival. This study was d...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2005.00426.x

    authors: Ohba K,Miyata Y,Koga S,Nishikido M,Kanetake H,Nazneen A,Razzaque MS,Taguchi T

    更新日期:2005-12-01 00:00:00

  • Use of G-CSF-stimulated marrow in allogeneic hematopoietic stem cell transplantation settings: a comprehensive review.

    abstract::In recent years, several researchers have unraveled the previously unrecognized effects of granulocyte colony-stimulating factor (G-CSF) on hematopoiesis and the immune cell functions of bone marrow in healthy donors. In human leukocyte antigen-matched or haploidentical transplant settings, available data have establi...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/j.1399-0012.2010.01298.x

    authors: Chang YJ,Huang XJ

    更新日期:2011-01-01 00:00:00

  • Donor polymorphisms in Toll-like receptor-4 influence the development of rejection after renal transplantation.

    abstract:BACKGROUND:Although innate immunity is crucial to host defense against pathogens, the extent to which innate immune mechanisms participate in the rejection of allogenic tissues in humans is unknown. We hypothesize that activation of innate immunity through Toll-like receptors (TLRs) critically regulates the development...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2005.00436.x

    authors: Palmer SM,Burch LH,Mir S,Smith SR,Kuo PC,Herczyk WF,Reinsmoen NL,Schwartz DA

    更新日期:2006-01-01 00:00:00

  • Urinary microbiome associated with chronic allograft dysfunction in kidney transplant recipients.

    abstract:BACKGROUND:We performed a study to identify differences in the urinary microbiome associated with chronic allograft dysfunction (CAD) and compared the urinary microbiome of male and female transplant recipients with CAD. METHODS:This case-control study enrolled 67 patients within the Deterioration of Kidney Allograft ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13436

    authors: Wu JF,Muthusamy A,Al-Ghalith GA,Knights D,Guo B,Wu B,Remmel RP,Schladt DP,Alegre ML,Oetting WS,Jacobson PA,Israni AK

    更新日期:2018-12-01 00:00:00

  • HMGCoA reductase inhibitors and omega-3 fatty acids as adjunctive agents in maintenance immunosuppression after solid organ transplantation.

    abstract::Omega-3 fatty acids have been shown to play a role in preventing development of both acute and chronic rejection. New evidence also suggests that HMGCoA reductase inhibitors may have an immunomodulatory effect and may decrease the incidence of rejection in both animal and human transplant models. Omega-3 fatty acids a...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:

    authors: Katznelson S,Wilkinson AH

    更新日期:1995-06-01 00:00:00

  • Functional assessment of immune markers of graft rejection: a comprehensive study in live-related donor renal transplantation.

    abstract::A better understanding of the immunobiological processes and predictors of graft rejection holds promise for the development of potential therapeutic strategies and also individualization of immunosuppression. The objective of this study is to analyze the clinical relevance of immune parameters such as antidonor antih...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2005.00445.x

    authors: Panigrahi A,Deka R,Bhowmik D,Dash SC,Tiwari SC,Guleria S,Mehta SN,Mehra NK

    更新日期:2006-01-01 00:00:00

  • Association between opioid use and readmission following liver transplantation.

    abstract::The aim of this study was to assess the independent association between pre-transplant prescription opioid use and readmission following liver transplantation. We reviewed the medical records of all patients at a single medical center undergoing primary, single-organ, liver transplantation from 2004 to 2014. We assess...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12806

    authors: Rogal S,Mankaney G,Udawatta V,Good CB,Chinman M,Zickmund S,Bielefeldt K,Jonassaint N,Jazwinski A,Shaikh O,Hughes C,Humar A,DiMartini A,Fine MJ

    更新日期:2016-10-01 00:00:00

  • Analysis of local versus imported expanded criteria donor kidneys: A single-center experience with 497 ECD kidney transplants.

    abstract:BACKGROUND:The value of importing expanded criteria donor (ECD) kidneys is uncertain. METHODS:We retrospectively reviewed our single-center experience with ECD kidney transplants (KT). RESULTS:Over 12.8 years, we performed 497 ECD KTs including 247 local and 250 imported from other donor service areas. The import ECD...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13029

    authors: Khan MA,El-Hennawy H,Farney AC,Rogers J,Orlando G,Reeves-Daniel A,Palanisamy A,Gautreaux M,Iskandar S,Doares W,Kaczmorski S,Stratta RJ

    更新日期:2017-08-01 00:00:00

  • High prevalence of colon adenomas in end-stage kidney disease patients on hemodialysis undergoing renal transplant evaluation.

    abstract::The aim of this study was to determine whether patients with end-stage kidney disease (ESKD) on hemodialysis (HD) undergoing kidney transplant evaluation are at higher risk for colonic neoplasia than the general population. This is a retrospective cohort study of patients with ESKD who underwent a first screening colo...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12684

    authors: Saumoy M,Jesudian AB,Aden B,Serur D,Sundararajan S,Sivananthan G,Gambarin-Gelwan M

    更新日期:2016-03-01 00:00:00

  • Plasma mycophenolic acid concentration and the clinical outcome after lung transplantation.

    abstract:BACKGROUND:The therapeutic drug monitoring of mycophenolic acid (MPA) has been investigated for renal and heart transplantations; however, its usefulness in lung transplantation is unclear. METHODS:The MPA area under the plasma concentration-time curve (AUC) was calculated in 59 adult lung transplant recipients. The M...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.14088

    authors: Yabuki H,Matsuda Y,Watanabe T,Eba S,Hoshi F,Hirama T,Oishi H,Sado T,Noda M,Sakurada A,Kikuchi M,Yamaguchi H,Mano N,Okada Y

    更新日期:2020-12-01 00:00:00

  • Need for tracheostomy after lung transplant predicts decreased mid- and long-term survival.

    abstract:BACKGROUND:Tracheostomy is an important adjunct for lung transplant patients requiring prolonged ventilation. We explored the effects of post-transplant tracheostomy on survival and bronchiolitis obliterans syndrome after lung transplant. METHODS:A retrospective, single center analysis was performed on all lung transp...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13766

    authors: Huddleston SJ,Brown R,Rudser K,Goswami U,Tomic R,Lemke NT,Shaffer AW,Soule M,Hertz M,Shumway S,Kelly R,Loor G

    更新日期:2020-01-01 00:00:00

  • Kidney graft survival in patients with hepatitis C: a single center experience.

    abstract::Hepatitis C virus (HCV) infection is highly prevalent in renal transplant candidates; however, its effect on the transplant outcome is still controversial. The aim of the present study was to determine the effect of HCV infection in the outcome of kidney transplantation in a single transplant center. The study populat...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2007.00679.x

    authors: Arango J,Arbelaez M,Henao J,Mejia G,Arroyave I,Carvajal J,Garcia A,Gutierrez J,Velásquez A,Garcia L,Aguirre C

    更新日期:2008-01-01 00:00:00

  • Pre-transplant alpha-fetoprotein is associated with post-transplant hepatocellular carcinoma recurrence mortality.

    abstract:BACKGROUND:Although liver transplantation may potentially cure hepatocellular carcinoma (HCC), the risk of HCC recurrence is 8%-20% at five years post-transplant. Pre-transplant alpha-fetoprotein (AFP) is a predictor of HCC recurrence, but it is unknown if pre-transplant AFP also predicts survival in patients with recu...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13634

    authors: Mahmud N,John B,Taddei TH,Goldberg DS

    更新日期:2019-07-01 00:00:00

  • Heart transplantation in the early phase of the COVID-19 pandemic: A single-center case series.

    abstract::The infectious disease coronavirus disease 2019 (COVID-19) was declared a pandemic by the World Health Organization in March 2020. The impact of COVID-19 on solid organ transplantations, including heart transplantation, is currently unclear. Many transplant programs have been forced to swiftly re-evaluate and adapt th...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.14042

    authors: Hsu JJ,Al-Saffar F,Ardehali R,Baas AS,Carlson M,Cruz D,Deng M,Fan A,Fraschilla S,Gaynor P,Kamath M,Kubak BM,Schaenman J,Stimpson E,Vucicevic D,Ardehali A,Nsair A

    更新日期:2020-09-01 00:00:00

  • Granulomatous tubulointerstitial nephritis in a renal allograft: three cases report and review of literature.

    abstract::Granulomatous interstitial nephritis (GIN) is a rare histologic diagnosis in renal allografts. We report three cases with GIN. Case 1: a 37-yr-old woman received a kidney from her mother. On follow-up 15 months later, serum creatinine was increased and a graft biopsy showed epithelioid granuloma in the center of massi...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/j.1399-0012.2012.01643.x

    authors: Hotta K,Fukasawa Y,Sasaki H,Seki T,Togashi M,Harada H

    更新日期:2012-07-01 00:00:00

  • Living donor evaluation and exclusion: the Stanford experience.

    abstract:BACKGROUND:The proportion of prospective living donors disqualified for medical reasons is unknown. The objective of this study is to delineate and quantify specific reasons for exclusion of prospective living donors from kidney donation. METHODS:All adult prospective kidney donors who contacted our transplant program...

    journal_title:Clinical transplantation

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1399-0012.2010.01336.x

    authors: Lapasia JB,Kong SY,Busque S,Scandling JD,Chertow GM,Tan JC

    更新日期:2011-09-01 00:00:00

  • Tuberculosis in southern Chinese renal-transplant recipients.

    abstract:OBJECTIVES:To analyze the characteristics of tuberculosis (TB) in Southern Chinese renal transplant recipients, and summarize the corresponding experiences in diagnosis and management. METHOD:Retrospectively study 41 documented post-transplant TB cases out of the 2333 patients who received kidney transplantation in th...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2008.00878.x

    authors: Chen SY,Wang CX,Chen LZ,Fei JG,Deng SX,Qiu J,Li J,Chen GO,Fu HM,Xie CM

    更新日期:2008-11-01 00:00:00

  • Interstitial alterations in renal cortex in acute tubular necrosis (ATN) post-renal transplantation and in patients with ATN not related to renal transplant.

    abstract:BACKGROUND:Abnormalities of renal function with long-term implications can persist after acute tubular necrosis (ATN), probably because of permanent loss of nephrons. Residual areas of fibrosis are also observed in the renal cortex post-ATN. In this study, we investigate the interstitial alterations post-ATN using hist...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1046/j.1399-0012.2003.00140.x

    authors: Moyses Neto M,Costa RS,Volpini RA,Garcia TM,Rodrigues FF,Coimbra TM

    更新日期:2004-04-01 00:00:00

  • The impact of obesity in renal transplantation: an analysis of paired cadaver kidneys.

    abstract:BACKGROUND:Previous studies indicate that obesity is a risk factor in renal transplantation. However, these analyses did not control for variable donor factors that may strongly influence outcome. To control for donor variables such as age, cause of death, procurement techniques, preservation methods, cold ischaemia ti...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1034/j.1399-0012.2002.01080.x

    authors: Yamamoto S,Hanley E,Hahn AB,Isenberg A,Singh TP,Cohen D,Conti DJ

    更新日期:2002-08-01 00:00:00

  • Complications related to totally implantable venous access devices in children and adults following lung transplantation.

    abstract:INTRODUCTION:Totally implantable venous access devices (TIVADs) are the preferred devices for patients with advanced lung disease who require long-term venous access. The primary purpose of this study was to describe the natural history of TIVADs left in place at the time of transplant. METHODS:This multicenter retros...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,多中心研究

    doi:10.1111/ctr.13465

    authors: Cho JK,Acord M,Goldfarb SB,Reddy SN,Goldberg HJ,Courtwright AM

    更新日期:2019-02-01 00:00:00

  • Steroid withdrawal in pancreas transplant recipients.

    abstract:BACKGROUND:Numerous studies of steroid withdrawal have been carried out in kidney and liver transplant recipients, but only a few in pancreas transplant recipients. Yet, pancreas transplant recipients could have significant long-term benefits from steroid withdrawal. METHODS:We performed a retrospective analysis to de...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1034/j.1399-0012.2000.140114.x

    authors: Humar A,Parr E,Drangstveit MB,Kandaswamy R,Gruessner AC,Sutherland DE

    更新日期:2000-02-01 00:00:00

  • Disparity in access to kidney allograft offers among transplant candidates with human immunodeficiency virus.

    abstract:BACKGROUND:Despite a survival benefit from transplantation and acceptable outcomes, patients with human immunodeficiency virus (HIV+) face barriers to kidney transplantation. Little is known about the acceptance or decline of organ offers on their behalf because waitlist registry data do not include HIV serostatus. ME...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13466

    authors: Cohen JB,Locke JE,Shelton B,Reed RD,Mustian M,MacLennan P,Forde KA,Reese PP,Sawinski D

    更新日期:2019-02-01 00:00:00

  • Post-transplant changes of segment 4 after living related liver transplantation.

    abstract::The purpose of this study was to evaluate the outcome of the medial segment of the graft after living related liver transplantation (LRLT). Of the 12 pediatric recipients who underwent LRLT, 2 received whole left liver graft, 1 left lateral segment graft, and 9 extended left lateral segment grafts. The hepatic veins o...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:

    authors: Cheng YF,Chen CL,Haung TL,Lee TY,Chen TY,Chen YS,Liu PP,Chiang YC,Eng HL,Wang CC,Cheung HK,Jawan B,Goto S

    更新日期:1998-10-01 00:00:00

  • Bone fractures and lumbar mineral density after renal transplantation. A long-term cross-sectional study.

    abstract:BACKGROUND:The purpose of this work was to investigate the association of vertebral and peripheral fractures 10 yr after grafting with bone metabolic markers and body mass density (BMD). PATIENTS AND METHODS:One hundred thirty-eight recipients with stable graft function were included in a cross-sectional study. Graft ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12666

    authors: Jiménez S,Marcén R,Vaamonde C,Caballero C,Fernández-Rodríguez A,Villafruela JJ,Galeano C,Teruel JL,Quereda C

    更新日期:2016-02-01 00:00:00