New pieces of the pathogenetic mosaic in inflammatory bowel disease.

abstract：OBJECTIVE:Hepcidin is an endogenous antimicrobial peptide with a key role in iron homoeostasis. Hepcidin is similar to defensin, the deficiency of which is associated with Crohn's disease. To date there has been no validated method to reliably assay serum hepcidin. We studied iron indices in inflammatory bowel disease ...

journal_title：European journal of gastroenterology & hepatology

authors： Arnold J,Sangwaiya A,Bhatkal B,Geoghegan F,Busbridge M

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVES:Although all international guidelines state that there is no indication to perform a faecal occult blood test (FOBT) in symptomatic patients, we believe the test is frequently used as a diagnostic test. The objective of this study was to investigate whether the current guidelines for FOBT use are being follo...

journal_title：European journal of gastroenterology & hepatology

authors： van Rijn AF,Stroobants AK,Deutekom M,Lauppe C,Sturk A,Bossuyt PM,Fockens P,Dekker E

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND AND AIM:Recently, the Inflammatory Bowel Disease-Disability Index (IBD-DI) was developed to assess disability in inflammatory bowel disease (IBD). Our aim was to validate the Portuguese version of IBD-DI according to the COnsensus-based Standards for the selection of the health Measurement INstruments (COSMI...

journal_title：European journal of gastroenterology & hepatology

authors： Soares JB,Pereira R,Costa JM,Arroja B,Gonçalves R

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:Primary porcine hepatocytes are commonly, used in bioartificial liver devices and for in vitro studies of hepatocyte function. Although in vivo isolation of porcine hepatocytes can give high yield and viability, such methods are time-consuming and expensive, requiring specialist surgical facilities. AIM:T...

journal_title：European journal of gastroenterology & hepatology

authors： Nelson LJ,Newsome PN,Howie AF,Hadoke PW,Dabos KJ,Walker SW,Hayes PC,Plevris JN

更新日期：2000-08-01 00:00:00

abstract：AIM:To review the evidence that Helicobacter pylori promotes gastric carcinogenesis, with particular reference to gastric epithelial proliferation. MATERIALS AND METHODS:Gastric epithelial kinetics were reviewed and a series of studies of gastric mucosal proliferation in H. pylori-associated gastritis were performed i...

journal_title：European journal of gastroenterology & hepatology

authors： Lynch DA,Axon AT

更新日期：1995-08-01 00:00:00

abstract：:A hypothesis about the inflammatory etiopathogeny mediated by astroglia of hepatic encephalopathy is being proposed. Three evolutive phases are considered in chronic hepatic encephalopathy: an immediate or nervous phase with ischemia-reperfusion, which is associated with reperfusion injury, edema and oxidative stress;...

journal_title：European journal of gastroenterology & hepatology

authors： Arias JL,Aller MA,Sánchez-Patan F,Arias J

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVES:Alpha-fetoprotein (AFP) and protein induced by vitamin K absence or antagonist-II (PIVKA-II) are used as tumour markers for the diagnosis of hepatocellular carcinoma (HCC). We investigate whether combined liver function marker such as gamma-glutamyl transferase (GGT) and aspartate aminotransferase (AST) with...

journal_title：European journal of gastroenterology & hepatology

authors： Ekmen N,Akalin Ç,Akyildiz M

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Varices are a late complication in primary biliary cirrhosis (PBC). However, patients without clinical jaundice do bleed from varices; whether their prognosis differs is unknown. AIM:Evaluate PBC patients, particularly those with bilirubin

journal_title：European journal of gastroenterology & hepatology

authors： Vlachogiannakos J,Carpenter J,Goulis J,Triantos C,Patch D,Burroughs AK

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:As treatment of steroid-dependent patients with inflammatory bowel disease (IBD) is controversial, we analysed the efficacy and tolerance of 6-mercaptopurine (6-MP) and methotrexate (MTX) added to prednisone in increasing and maintaining the disease remission rate. METHODS:Seventy-two steroid-dependent IBD ...

journal_title：European journal of gastroenterology & hepatology

authors： Maté-Jiménez J,Hermida C,Cantero-Perona J,Moreno-Otero R

更新日期：2000-11-01 00:00:00

abstract：:With the growing popularity and use of herbal remedies in the industrial countries there has been an increasing recognition and reporting of adverse reactions. Drug development represents discovery and characterization of naturally occurring plant metabolites or their synthetic analogues. Therefore, a herbal remedy sh...

journal_title：European journal of gastroenterology & hepatology

authors： Aithal GP

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:The detection of bacterial DNA in serum and ascitic fluid from patients with cirrhosis and ascites is interpreted as molecular evidence of intestinal bacterial translocation and considered sufficient to activate the cellular immune response. In vitro studies on ascitic fluid culture have shown a close relati...

journal_title：European journal of gastroenterology & hepatology

authors： Francés R,Rodríguez E,Muñoz C,Zapater P,De la ML,Ndongo M,Pérez-Mateo M,Such J

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Several studies have reported associations of proton pump inhibitor (PPI) treatment with the incidence of complications and even increased mortality in patients with liver cirrhosis. Up to now, there are no studies on the impact of PPI treatment in patients with hepatocellular carcinoma (HCC). There...

journal_title：European journal of gastroenterology & hepatology

authors： Sturm L,Muller L,Schultheiss M,Binder B,Huber JP,Thimme R,Bettinger D

更新日期：2020-12-14 00:00:00

abstract：:Intraductal papillary mucinous neoplasms (IPMNs), characterized by intraductal papillary growth and thick mucin secretion, have increasingly been recognized. Despite modern preoperative evaluation, major difficulties still remain in distinguishing malignant invasive types from benign IPMNs. Following a PubMed database...

journal_title：European journal of gastroenterology & hepatology

authors： Dongbin L,Fei L,Werner Josefin B,Roland A

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVES:Hepatitis C virus (HCV) is the major cause of cryoglobulinemia. Direct-acting antivirals (DAAs) have markedly changed the therapeutic outcomes in the treatment of patients with HCV. We evaluate the efficacy, safety, immunological, and clinical response of different DAA regimens in HCV-cryoglobulinemia. PATI...

journal_title：European journal of gastroenterology & hepatology

authors： Passerini M,Schiavini M,Magni CF,Landonio S,Niero F,Passerini S,Croci AL,Bolis M,Scalzi V,Gubertini G,Ricci ED,Galli M,Rizzardini G

更新日期：2018-10-01 00:00:00

abstract：:Calprotectin is a promising diagnostic biomarker for spontaneous bacterial peritonitis (SBP) among cirrhotic patients, but published studies report a wide variation of its diagnostic accuracy. We systematically searched six databases for eligible studies (i.e., all original studies that reported ascitic calprotectin a...

journal_title：European journal of gastroenterology & hepatology

authors： Dibas M,Rajab AM,Zaghloul MS,Atiah MJ,Aljundi S,Amir A,Saquib N

更新日期：2020-09-01 00:00:00

abstract：:Arterio-biliary fistula is an uncommon cause of haemobilia. We describe a case of right hepatic artery pseudo-aneurysm causing arterio-biliary fistula and presenting as severe melaena and cholangitis. Gastroduodenoscopy failed to establish the exact source of bleeding and hepatic artery angiography and selective embol...

journal_title：European journal of gastroenterology & hepatology

authors： Rai R,Rose J,Manas D

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:Health expenditure is a marker associated with an advanced healthcare system, which contributes toward the good prognosis of patients. Mortality-to-incidence ratios (MIRs) are one of the predictors that reflect the prognosis of cancer patients. There remains some uncertainty on the correlation of MIRs of live...

journal_title：European journal of gastroenterology & hepatology

authors： Wang CC,Tsai MC,Peng CM,Lee HL,Chen HY,Yang TW,Sung WW,Lin CC

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:The distribution of the intestinal vascular lesions and their relation with the fibrinolysis process are poorly known in Crohn's disease (CD). The mediators of the plasminogen activator system, namely urokinase-type plasminogen activator (u-PA), tissue-type plasminogen activator (t-PA) and plasminogen activa...

journal_title：European journal of gastroenterology & hepatology

authors： Desreumaux P,Huet G,Zerimech F,Gambiez L,Balduyck M,Baron P,Degand P,Cortot A,Colombel JF,Janin A

更新日期：1999-10-01 00:00:00

abstract：:This review summarizes research studies published in recent years that are useful for clinicians considering the enteral route as a means of nutritional support for their patients. In this period, there has been a move away from emphasis on what nutrients are given to a more considered appraisal of how nutrients are p...

journal_title：European journal of gastroenterology & hepatology

authors： Payne-James JJ

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:To study the differences in mortality between terlipressin and somatostatin treatments in cirrhotic patients with esophageal variceal bleeding (EVB) and renal functional impairment (RFI). METHODS:The National Health Insurance Database, part of the Taiwan National Health Insurance Program, was used to enroll ...

journal_title：European journal of gastroenterology & hepatology

authors： Hung TH,Tsai CC,Tseng CW,Tseng KC,Hsieh YH,Tsai CC

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Adalimumab (ADA) is a subcutaneous anti-tumour necrosis factor (anti-TNF) agent, effective in inducing and maintaining remission in Crohn's disease (CD). Unlike Infliximab (IFX), ADA dosing is not weight adjusted and dose frequency is based on clinical response. AIM:To determine whether obesity is a risk fa...

journal_title：European journal of gastroenterology & hepatology

authors： Bhalme M,Sharma A,Keld R,Willert R,Campbell S

更新日期：2013-05-01 00:00:00

abstract：INTRODUCTION:Colorectal cancer (CRC) is one of the most serious health problems worldwide and thus it is important to assess health and economic impacts of preventative CRC screening strategies. METHODS:For this reason, a theoretical model based on Markov chains is proposed to compare these strategies: fecal occult bl...

journal_title：European journal of gastroenterology & hepatology

authors： Wohl P,Bednařík M,Wohl P,Cervenka M,Spičák J

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:Immunoproliferative small intestinal disease (IPSID) represents a spectrum of clinicopathological entities including alpha-chain disease and other types of lymphoplasmacytic proliferations of the lamina propria of the small intestine, presenting with severe malabsorption. IPSID has been described mainly in t...

journal_title：European journal of gastroenterology & hepatology

authors： Economidou I,Manousos ON,Triantafillidis JK,Vaslamatzis MM,Zafiropoulou R,Papadakis T

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Although the number of ulcerative colitis patients has increased rapidly in Japan, few reports have been published regarding their clinical aspects. We investigated the clinical characteristics and chronological change of ulcerative colitis in Japanese patients. METHODS:Patients diagnosed with ulcerative co...

journal_title：European journal of gastroenterology & hepatology

authors： Fujimoto T,Kato J,Nasu J,Kuriyama M,Okada H,Yamamoto H,Mizuno M,Shiratori Y,Japan West Ulcerative Colitis (JWUC) Study Group.

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:Irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) have similar symptoms, and both adversely affect patients' quality of life. The objective of this study was to compare the perceptions of physicians and nurses regarding IBS and IBD. METHODS:The Illness Perception Questionnaire Revised, adap...

journal_title：European journal of gastroenterology & hepatology

authors： Dickman R,Segev M,Levi S,Reicher-Atir R,Steinmetz A,Horev N,Niv Y

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Patients with inflammatory bowel disease (IBD) have a higher risk of developing thromboembolic events (TE) compared with the healthy population. AIM:This study aimed to describe a cohort of IBD patients with a history of TE focusing on recurrence of TE, disease activity and IBD medication at the time of TE ...

journal_title：European journal of gastroenterology & hepatology

authors： Bollen L,Vande Casteele N,Ballet V,van Assche G,Ferrante M,Vermeire S,Gils A

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Data from studies in patients with nonalcoholic steatohepatitis (NASH) suggest an increased hepatic fatty acid oxidation. We have previously shown higher fasting plasma bile acid concentrations in patients with NASH. In-vivo and in-vitro studies suggest that bile acids by binding to peroxisome proliferator-a...

journal_title：European journal of gastroenterology & hepatology

authors： Dasarathy S,Yang Y,McCullough AJ,Marczewski S,Bennett C,Kalhan SC

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To investigate the subclinical cardiac morphological and functional modifications in cirrhotic patients according to the stage of liver disease. PATIENTS AND METHODS:One hundred and thirteen cirrhotic patients underwent standard Doppler echocardiography and were compared with healthy individuals. Left ventri...

journal_title：European journal of gastroenterology & hepatology

authors： Cesari M,Fasolato S,Rosi S,Angeli P

更新日期：2015-06-01 00:00:00

abstract：:A 30-year-old previously healthy woman was diagnosed as having a vasoactive intestinal polypeptide (VIP)-producing tumour of the pancreas. Her medical history was typical for neuroendocrine gastrointestinal tumours, presenting initially with non-specific symptoms but eventually she developed life-threatening manifesta...

journal_title：European journal of gastroenterology & hepatology

authors： Sjöqvist U,Permert J,Löfberg R,Larsson J,Gadaleanu V,Adrian TE

更新日期：1998-11-01 00:00:00

abstract：:Diabetes mellitus (DM) is a well known complication of interferon therapy for chronic hepatitis C virus (HCV) infection, but resolution of interferon-induced DM was rarely reported. In HIV and HCV co-infected patients, only two cases of incident DM during interferon therapy were reported and both cases required perman...

journal_title：European journal of gastroenterology & hepatology

authors： Lo YC,Chang SY,Sheng WH,Hung CC,Chang SC

更新日期：2009-04-01 00:00:00