Inappropriate use of the faecal occult blood test in a university hospital in the Netherlands.

Abstract:

OBJECTIVES:Although all international guidelines state that there is no indication to perform a faecal occult blood test (FOBT) in symptomatic patients, we believe the test is frequently used as a diagnostic test. The objective of this study was to investigate whether the current guidelines for FOBT use are being followed in the Netherlands. METHODS:The frequency of reasons for ordering a FOBT in 15 hospitals over a time period of 1 year was determined and the consequences of the test result on the diagnostic workup were determined by a retrospective search of electronic hospital charts. RESULTS:In 14 of the 15 hospitals a FOBT was available and totally 2993 FOBTs were performed in 1 year. A total of 201 electronic charts were retrieved. The FOBTs were ordered because of anaemia (41%), suspicion of rectal bleeding (17%), abdominal pain (14%), changed bowel habits (10%) or others (18%). A positive test result was found in 66 (33%) patients and a negative in 133 (66%). Respectively, 38% (25/66) of the patients with a positive and 41% (55/133) of the patients with a negative test result received a gastrointestinal follow-up investigation. In 25/80 investigations, a possible cause of rectal blood loss was detected, of which 13 had a positive FOBT result. CONCLUSION:This study demonstrates that current guidelines on FOBT use are not followed in the Netherlands and that a FOBT is often used as a diagnostic tool instead of a screening tool, thereby causing confusion and unnecessary delays in the diagnostic workup of patients.

authors

van Rijn AF,Stroobants AK,Deutekom M,Lauppe C,Sturk A,Bossuyt PM,Fockens P,Dekker E

doi

10.1097/MEG.0b013e328313bbd3

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

1266-9

issue

11

eissn

0954-691X

issn

1473-5687

pii

00042737-201211000-00004

journal_volume

24

pub_type

杂志文章
  • Determination of hepatitis C virus genotypes circulating in different districts of Punjab (Pakistan).

    abstract:INTRODUCTION:Hepatitis C virus (HCV) is a principal cause of severe liver diseases worldwide and a possible source of significant morbidity and fatality in the long term. Information on the genotype is more significant because it has prognostic value in the response to antiviral therapy. OBJECTIVES:This study aimed to...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,meta分析

    doi:10.1097/MEG.0b013e328362dc3f

    authors: Waqar M,Khan AU,Rehman HU,Idrees M,Wasim M,Ali A,Niaz Z,Ismail Z,Rehman MU,Tariq M,Shah M,Murtaza BN

    更新日期:2014-01-01 00:00:00

  • Key points from the revised Maastricht Consensus Report: the impact on general practice.

    abstract::The Maastricht 2 Consensus Report features evidence-based recommendations for the management of Helicobacter pylori infection. Strongly recommended indications for H. pylori eradication include duodenal and gastric ulcer, mucosa-associated lymphoid tissue lymphoma, atrophic gastritis, post gastric cancer resection, fi...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:

    authors: Bazzoli F

    更新日期:2001-08-01 00:00:00

  • One-week low-dose triple therapy for the eradication of Helicobacter pylori infection.

    abstract:OBJECTIVE:To evaluate the efficacy and safety of two 1-week low-dose triple therapy regimens for the treatment of Helicobacter pylori infection. PATIENTS AND METHODS:Eighty patients with H. pylori infection and peptic ulcer disease (n = 64) or functional dyspepsia (n = 16), with similar demographic and clinical charac...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Labenz J,Stolte M,Rühl GH,Becker T,Tillenburg B,Sollböhmer M,Börsch G

    更新日期:1995-01-01 00:00:00

  • Viridans group streptococci: an underestimated cause of spontaneous bacterial peritonitis in cirrhotic patients with ascites.

    abstract:OBJECTIVES:The objective of the study was to examine the characteristics of spontaneous bacterial peritonitis (SBP) caused by streptococci, in particular viridans group streptococci (VGS), and to investigate a potential association between the long-term administration of norfloxacin and high-level resistance to fluoroq...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200509000-00008

    authors: Bert F,Noussair L,Lambert-Zechovsky N,Valla D

    更新日期:2005-09-01 00:00:00

  • Effect of omeprazole on Helicobacter pylori urease activity in vivo.

    abstract:BACKGROUND:Detection of Helicobacter pylori infection in clinical routine is based either on the direct visualization of the bacterium in gastric biopsies by histology or microbiology or on the demonstration of urease activity in gastric biopsies and by the labelled-urea breath test (UBT). Omeprazole has a strong inhib...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Stoschus B,Domínguez-Muñoz JE,Kalhori N,Sauerbruch T,Malfertheiner P

    更新日期:1996-08-01 00:00:00

  • Helicobacter pylori infection is unlikely to be transmitted between partners: evidence from genotypic study in partners of infected patients.

    abstract:INTRODUCTION:We postulated that the oro-oral route of transmission between spouses could be an important route of transmission of Helicobacter pylori. AIMS:To estimate the prevalence of different genotypes of H. pylori as distinguished by the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200205000-00009

    authors: Luman W,Zhao Y,Ng HS,Ling KL

    更新日期:2002-05-01 00:00:00

  • Short-acting general anaesthesia facilitates therapeutic ERCP in frail elderly patients with benign extra-hepatic biliary disease.

    abstract:AIMS AND OBJECTIVES:To ascertain whether therapeutic endoscopic retrograde cholangiopancreatography (ERCP) for benign biliary disease in frail elderly patients with comorbid conditions can be safely undertaken in a district general hospital, and whether the procedure is facilitated by the use of short-acting general an...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200012040-00014

    authors: Cocking JB,Ferguson A,Mukherjee SK,Giancola G

    更新日期:2000-04-01 00:00:00

  • Acoustic radiation force impulse: a new ultrasonographic technology for the widespread noninvasive diagnosis of liver fibrosis.

    abstract:BACKGROUND/AIMS:As a module of a standard ultrasound imaging device, acoustic radiation force impulse (ARFI) is a new technology for liver stiffness evaluation (LSE). We aimed to evaluate accuracy, feasibility, reproducibility, and training effect of ARFI for liver fibrosis evaluation. METHODS:One hundred and one pati...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 临床试验,杂志文章

    doi:10.1097/MEG.0b013e328339e0a1

    authors: Boursier J,Isselin G,Fouchard-Hubert I,Oberti F,Dib N,Lebigot J,Bertrais S,Gallois Y,Calès P,Aubé C

    更新日期:2010-09-01 00:00:00

  • Serological markers of autoimmunity in children with hepatitis A: relation to acute and fulminant presentation.

    abstract:OBJECTIVES:Hepatitis A virus (HAV) infection tends to be a self-limiting disease without serious sequelae, but fulminant hepatitis, with a high mortality, develops in 0.1-0.2% of the cases. Sometimes, HAV infection precipitates autoimmune hepatitis (AIH). We aimed to assess the frequency and clinical significance of se...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000413

    authors: Abdel-Ghaffar TY,Sira MM,Sira AM,Salem TA,El-Sharawy AA,El Naghi S

    更新日期:2015-10-01 00:00:00

  • Qualitative and quantitative clinical evaluation of the laser-assisted ratio analyser for detection of Helicobacter pylori infection by (13)C-urea breath tests.

    abstract:OBJECTIVES:Currently, the (13)C-urea breath test is the reference method for non-invasive diagnosis of Helicobacter pylori infection and therapy control. Therefore, new technologies have been developed to measure the ratio of (13)CO(2)/(12)CO(2) in breath. The laser-assisted ratio analyser (LARA) device is based on opt...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-200107000-00008

    authors: Braden B,Gelbmann C,Dietrich CF,Caspary WF,Schölmerich J,Lock G

    更新日期:2001-07-01 00:00:00

  • Faecal microbiota transplantation: what's beyond Clostridium difficile infection?

    abstract::Over the last decade, major advancements have been made in our understanding of both the beneficial and detrimental role that microorganisms play in our innate functioning. Research into the intestinal microbiota has moved from the laboratory into our medical clinics and is being put forth as an effective therapy for ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001938

    authors: Tamilarasan AG,Krishnananthan T

    更新日期:2020-11-10 00:00:00

  • Acid-base disturbance in patients with cirrhosis: relation to hemodynamic dysfunction.

    abstract:PURPOSE:Acid-base disturbances were investigated in patients with cirrhosis in relation to hemodynamic derangement to analyze the hyperventilatory effects and the metabolic compensation. METHODS:A total of 66 patients with cirrhosis and 44 controls were investigated during a hemodynamic study. RESULTS:Hyperventilator...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000382

    authors: Henriksen JH,Bendtsen F,Møller S

    更新日期:2015-08-01 00:00:00

  • Role of ursodeoxycholic acid on maternal serum bile acids and perinatal outcomes in intrahepatic cholestasis of pregnancy.

    abstract:AIM:Intrahepatic cholestasis of pregnancy (ICP) is associated with safe maternal outcomes but perinatal outcomes have been variable. We assessed clinical factors and impact of bile acid levels on maternal and neonatal outcomes in ICP. METHODS:Patients with ICP (defined as pruritus with serum bile acids ≥ 10 mmol/l) we...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001954

    authors: Roy A,Premkumar M,Mishra S,Mehtani R,Suri V,Aggarwal N,Singh S,Dhiman RK

    更新日期:2020-10-29 00:00:00

  • Heparanase-2, syndecan-1, and extracellular matrix remodeling in colorectal carcinoma.

    abstract:AIM:To propose a quantitative method to detect heparanase-2 (HPA2) and syndecan-1 (Syn-1) using immunohistochemistry in colorectal (colon and rectal) carcinomas compared with nonneoplastic tissues and evaluate the possible role of these molecules in tumor development and extracellular remodeling. METHODS:Cytoplasmic s...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e3282fc2649

    authors: Peretti T,Waisberg J,Mader AM,de Matos LL,da Costa RB,Conceição GM,Lopes AC,Nader HB,Pinhal MA

    更新日期:2008-08-01 00:00:00

  • Papillary adenoma arising in the left hepatic duct: an unusual tumour in an uncommon location.

    abstract::Bile duct adenomas are rare tumours that arise more frequently in the distal extrahepatic biliary tree. We report the case of a papillary adenoma arising at the junction of the common and left hepatic ducts and review the available literature on this rare entity. A 73-year-old lady presented with a history of mild wei...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:10.1097/meg.0b013e3283392a62

    authors: Morris-Stiff GJ,Senda Y,Verbeke CS,Lodge PA

    更新日期:2010-07-01 00:00:00

  • Sigmoidoscopy and rectal biopsy: a survey of current UK practice.

    abstract:OBJECTIVE:To establish the pattern of practice of sigmoidoscopy and rectal biopsy in the UK, and to estimate the rate of occurrence of important complications. DESIGN:Postal questionnaire enquiring about practice in the previous 2 years. SUBJECTS:Consultant members of the British Society of Gastroenterology. MAIN OU...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-199602000-00011

    authors: Robinson RJ,Stone M,Mayberry JF

    更新日期:1996-02-01 00:00:00

  • Short article: A randomized-controlled study of sitagliptin for treating diabetes mellitus complicated by nonalcoholic fatty liver disease.

    abstract:BACKGROUND:This study aimed to evaluate the efficacy and safety of sitagliptin for treating Chinese patients with type 2 diabetes mellitus (T2DM) with nonalcoholic fatty liver disease (NAFLD). METHODS:In total, 72 Chinese T2DM patients with NAFLD were divided randomly into two groups of 36 patients each group. All 72 ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MEG.0000000000000780

    authors: Deng XL,Ma R,Zhu HX,Zhu J

    更新日期:2017-03-01 00:00:00

  • Deleterious effect of proton pump inhibitors on the disease course of cirrhosis.

    abstract:OBJECTIVES:Proton pump inhibitors(PPIs) are widely prescribed to patients with liver cirrhosis. We hypothesized that long-standing PPI use is associated with spontaneous bacterial peritonitis(SBP) and accelerated development of disease-specific complications and liver-related death. METHODS:A 5-year follow-up observat...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000001499

    authors: Janka T,Tornai T,Borbély B,Tornai D,Altorjay I,Papp M,Vitális Z

    更新日期:2020-02-01 00:00:00

  • Levofloxacin based regimens for the eradication of Helicobacter pylori.

    abstract:BACKGROUND:A 7 day treatment scheme based on rabeprazole/levofloxacin/amoxycillin or tinidazole achieved an eradication rate over 90%. However, the combination of drugs and duration of treatment for the correct use of levofloxacin in the eradication of are still unclear. OBJECTIVE:To compare the efficacy and tolerabil...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00042737-200212000-00004

    authors: Di Caro S,Zocco MA,Cremonini F,Candelli M,Nista EC,Bartolozzi F,Armuzzi A,Cammarota G,Santarelli L,Gasbarrini A

    更新日期:2002-12-01 00:00:00

  • Enteral nutrition.

    abstract::This review summarizes research studies published in recent years that are useful for clinicians considering the enteral route as a means of nutritional support for their patients. In this period, there has been a move away from emphasis on what nutrients are given to a more considered appraisal of how nutrients are p...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:

    authors: Payne-James JJ

    更新日期:1995-06-01 00:00:00

  • Hepcidin and inflammatory bowel disease: dual role in host defence and iron homoeostasis.

    abstract:OBJECTIVE:Hepcidin is an endogenous antimicrobial peptide with a key role in iron homoeostasis. Hepcidin is similar to defensin, the deficiency of which is associated with Crohn's disease. To date there has been no validated method to reliably assay serum hepcidin. We studied iron indices in inflammatory bowel disease ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e32830e2885

    authors: Arnold J,Sangwaiya A,Bhatkal B,Geoghegan F,Busbridge M

    更新日期:2009-04-01 00:00:00

  • Factors affecting abdominal pain during colonoscopy.

    abstract:OBJECTIVE:The actual degree of pain or discomfort experienced during colonoscopy varies between patients. This prospective study was conducted to determine what variables, apart from the endoscopist's skill, are associated with a patient's discomfort during this procedure. DESIGN/METHODS:From December 2003 to Septembe...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/01.meg.0000219097.32811.24

    authors: Park DI,Kim HJ,Park JH,Cho YK,Sohn CI,Jeon WK,Kim BI,Ryu SH,Sung IK

    更新日期:2007-08-01 00:00:00

  • Adjuvant chemotherapy for stage II colon cancer: influence of care structures' characteristics on a controversial clinical practice.

    abstract:BACKGROUND:Adjuvant chemotherapy for stage II colon cancer is a controversial practice and is not recommended by the French Consensus Conference outside of therapeutic trial. OBJECTIVE:To assess, within a well-defined population, the influence of hospital characteristics in this practice. PATIENTS AND METHODS:In the ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MEG.0b013e3282e1c5b7

    authors: Alter E,Phelip JM,Guilhot JN,Matysiak M,Vermorel M,Roblin X

    更新日期:2007-11-01 00:00:00

  • Prevalence of hepatitis B and C and factors for infection and nonimmune in inflammatory bowel disease patients in China.

    abstract:OBJECTIVE:The aims of this study were to investigate the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in inflammatory bowel disease (IBD) patients and the risk factors related to the infection and nonimmune status. METHODS:A retrospective study was carried out at two clinical centers. Th...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MEG.0000000000000838

    authors: Chen D,Luo S,Ben Q,Lu L,Wan X,Wu J

    更新日期:2017-05-01 00:00:00

  • Family history, comorbidity, smoking and other risk factors in microscopic colitis: a case-control study.

    abstract:OBJECTIVES:Data on heredity, risk factors and comorbidity in microscopic colitis, encompassing collagenous colitis (CC) and lymphocytic colitis (LC), are limited. AIM:The aim was to carry out a case-control study of family history, childhood circumstances, educational level, marital status, smoking and comorbidity in ...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0000000000000832

    authors: Wickbom A,Nyhlin N,Montgomery SM,Bohr J,Tysk C

    更新日期:2017-05-01 00:00:00

  • Effect of chronic treatment with nadolol plus isosorbide mononitrate on liver blood flow and liver metabolic activity in cirrhosis.

    abstract:OBJECTIVE:To assess the long-term effect of the addition of long-acting nitrates to beta-blockers on liver blood flow and liver metabolic activity in patients with cirrhosis and portal hypertension. METHODS:Eleven patients with cirrhosis and portal hypertension were investigated by using hepatic vein catheterization a...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/00042737-199911000-00006

    authors: Merkel C,Sacerdoti D,Bolognesi M,Buonamico P,Sticca A,Amodio P,Angeli P,Micotti L,Gatta A

    更新日期:1999-11-01 00:00:00

  • A randomized double-blinded sham-controlled cross-over trial of tined-lead sacral nerve stimulation testing for chronic constipation.

    abstract:OBJECTIVES:Sacral nerve stimulation (SNS) may provide long-term symptom relief to patients suffering from chronic constipation. Patients are currently selected for SNS using a 2-week peripheral nerve evaluation (PNE) comprising stimulation by temporary leads. However, only 40% of test responders receive long-term benef...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MEG.0000000000001379

    authors: Yiannakou Y,Etherson K,Close H,Kasim A,Mercer-Jones M,Plusa S,Maier R,Green S,Cundall J,Knowles C,Mason J

    更新日期:2019-06-01 00:00:00

  • Rifaximin for the prevention of spontaneous bacterial peritonitis and hepatorenal syndrome in cirrhosis: a systematic review and meta-analysis.

    abstract::Prophylactic antibiotics have been recommended in patients with a previous history of spontaneous bacterial peritonitis (SBP). Recently, there has been interest in the use of rifaximin for the prevention of SBP and hepatorenal syndrome (HRS). We conducted a meta-analysis to evaluate this association of rifaximin. We s...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MEG.0000000000000940

    authors: Kamal F,Khan MA,Khan Z,Cholankeril G,Hammad TA,Lee WM,Ahmed A,Waters B,Howden CW,Nair S,Satapathy SK

    更新日期:2017-10-01 00:00:00

  • Elevated hepatic fatty acid oxidation, high plasma fibroblast growth factor 21, and fasting bile acids in nonalcoholic steatohepatitis.

    abstract:BACKGROUND:Data from studies in patients with nonalcoholic steatohepatitis (NASH) suggest an increased hepatic fatty acid oxidation. We have previously shown higher fasting plasma bile acid concentrations in patients with NASH. In-vivo and in-vitro studies suggest that bile acids by binding to peroxisome proliferator-a...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章

    doi:10.1097/MEG.0b013e328345c8c7

    authors: Dasarathy S,Yang Y,McCullough AJ,Marczewski S,Bennett C,Kalhan SC

    更新日期:2011-05-01 00:00:00

  • Aspects of hepatitis C virus infection relating to liver transplantation.

    abstract::End-stage liver disease caused by the hepatitis C virus (HCV) is a major indication for liver transplantation. HCV re-infection after transplantation is almost constant, and recent data confirm that it significantly impairs patient and graft survival. Factors that may influence disease severity and consequent progress...

    journal_title:European journal of gastroenterology & hepatology

    pub_type: 杂志文章,评审

    doi:10.1097/00042737-200604000-00002

    authors: Roche B,Samuel D

    更新日期:2006-04-01 00:00:00