Association of pancreatic autoantibodies and human leukocyte antigen haplotypes with resolution of diabetes mellitus after therapy for hepatitis C virus infection in patients with HIV infection: case report and review of literature.

Abstract:

:Diabetes mellitus (DM) is a well known complication of interferon therapy for chronic hepatitis C virus (HCV) infection, but resolution of interferon-induced DM was rarely reported. In HIV and HCV co-infected patients, only two cases of incident DM during interferon therapy were reported and both cases required permanent insulin treatment. We report the first case of HIV/HCV co-infected patient who developed diabetic ketoacidosis during treatment for chronic HCV infection with complete resolution of DM after treatment cessation. Review of reported cases indicates that pancreatic autoantibodies and human leukocyte antigen haplotypes may predict the outcome of interferon-induced diabetes.

authors

Lo YC,Chang SY,Sheng WH,Hung CC,Chang SC

doi

10.1097/MEG.0b013e328317f4c8

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

478-81

issue

4

eissn

0954-691X

issn

1473-5687

pii

00042737-200904000-00016

journal_volume

21

pub_type

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