Influence of viral hepatitis on HIV infection.

abstract：BACKGROUND/AIMS:The independent role of soft drink consumption in non-alcoholic fatty liver disease (NAFLD) patients remains unclear. We aimed to assess the association between consumption of soft drinks and fatty liver in patients with or without metabolic syndrome. METHODS:We recruited 31 patients (age: 43+/-12 year...

journal_title：Journal of hepatology

authors： Abid A,Taha O,Nseir W,Farah R,Grosovski M,Assy N

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND & AIMS:The accuracy of creatinine-based estimated GFR (eGFR) in assessing the prevalence of chronic kidney disease (CKD) and associated mortality after liver transplantation (LTx) is unknown. Using measured GFR (mGFR) by iothalamate clearance, we determined the prevalence of the entire spectrum of renal dysf...

journal_title：Journal of hepatology

authors： Allen AM,Kim WR,Therneau TM,Larson JJ,Heimbach JK,Rule AD

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND/AIMS:The hypothesis that chronic alcohol ingestion potentiates iron-associated liver injury was investigated in the 'carbonyl iron-overload rat model'. METHODS:Newborn male and female Wistar-Furth rats (seven per group) were used to investigate iron-alcohol interaction over a 26-week period. Groups 1 and 2 ...

journal_title：Journal of hepatology

authors： Olynyk J,Hall P,Reed W,Williams P,Kerr R,Mackinnon M

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND/AIMS:Whether GB virus C and hepatitis G virus participate in fulminant hepatic failure is controversial. We studied the prevalence of the viral RNA in 48 patients. There were possible routes of infection, including blood transfusion, in 22 patients (group 1), and no risk factors in the other 26 (group 2). M...

journal_title：Journal of hepatology

authors： Tanaka M,Nishiguchi S,Tanaka T,Enomoto M,Fukuda K,Takeda T,Nakajima S,Shiomi S,Kuroki T,Monna T,Yano Y,Otani S

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND/AIMS:The pathogenesis of post-transplantation bone loss is poorly understood, although glucocorticoid therapy is believed to play an important role. In the present study we have measured plasma parathyroid hormone concentrations in the first few months after orthotopic liver transplantation, in order to exam...

journal_title：Journal of hepatology

authors： Compston JE,Greer S,Skingle SJ,Stirling DM,Price C,Friend PJ,Alexander G

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND & AIMS:Low levels of toll-like receptor 3 (TLR3) in patients with hepatocellular carcinoma (HCC) are associated with poor prognosis, primarily owing to the loss of inflammatory signaling and subsequent lack of immune cell recruitment to the liver. Herein, we explore the role of TLR3-triggered apoptosis in HC...

journal_title：Journal of hepatology

authors： Bonnin M,Fares N,Testoni B,Estornes Y,Weber K,Vanbervliet B,Lefrançois L,Garcia A,Kfoury A,Pez F,Coste I,Saintigny P,Viari A,Lang K,Guey B,Hervieu V,Bancel B,Bartoch B,Durantel D,Renno T,Merle P,Lebecque S

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND & AIMS:Aceruloplasminemia is a rare autosomal recessive neurodegenerative disease associated with brain and liver iron accumulation which typically presents with movement disorders, retinal degeneration, and diabetes mellitus. Ceruloplasmin is a multi-copper ferroxidase that is secreted into plasma and facil...

journal_title：Journal of hepatology

authors： Finkenstedt A,Wolf E,Höfner E,Gasser BI,Bösch S,Bakry R,Creus M,Kremser C,Schocke M,Theurl M,Moser P,Schranz M,Bonn G,Poewe W,Vogel W,Janecke AR,Zoller H

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND/AIM:The aim of this study was to assess the pathology and pathogenic mechanisms involved in the occlusion of transjugular intrahepatic portosystemic stent-shunts. METHODS:Thirty-four patients with transjugular intrahepatic portosystemic stent-shunt who had at least two portographic assessments of shunt func...

journal_title：Journal of hepatology

authors： Jalan R,Harrison DJ,Redhead DN,Hayes PC

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND & AIMS:Recently, we have shown that micro-metastases, in the hypoxic transition zone surrounding lesions generated by radiofrequency ablation (RFA), display strongly accelerated outgrowth. CD95 is best known for its ability to induce apoptosis but can also promote tumorigenesis in apoptosis-resistant tumor c...

journal_title：Journal of hepatology

authors： Nijkamp MW,Hoogwater FJ,Steller EJ,Westendorp BF,van der Meulen TA,Leenders MW,Borel Rinkes IH,Kranenburg O

更新日期：2010-12-01 00:00:00

abstract：:The case for using emergency liver transplantation in acute liver failure was made two decades ago by a series of single centre experiences. The development of models identifying a poor prognosis assisted the selection of patients for liver transplantation but none of these delivers both high sensitivity and specifici...

journal_title：Journal of hepatology

authors： O'Grady J

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND & AIMS:To compare the management and the virological and serological efficacy of treatments for chronic hepatitis B (CHB) in HIV positive and negative patients. METHODS:Two hundred and forty-six HIV positive and 205 HIV negative consecutive patients with past or present CHB, seen in October 2008 in particip...

journal_title：Journal of hepatology

authors： Piroth L,Pol S,Lacombe K,Miailhes P,Rami A,Rey D,Loustau-Ratti V,Morlat P,Goderel I,Sene D,Rosenthal E,Carrat F,Cacoub P,GERMIVIC Study Group.

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND & AIMS:Mutations in ABCB11 can cause deficiency of the bile salt export pump (BSEP), leading to cholestasis and end-stage liver disease. Owing to the rarity of the disease, the associations between genotype and natural history, or outcomes following surgical biliary diversion (SBD), remain elusive. We aimed ...

journal_title：Journal of hepatology

authors： van Wessel DBE,Thompson RJ,Gonzales E,Jankowska I,Sokal E,Grammatikopoulos T,Kadaristiana A,Jacquemin E,Spraul A,Lipiński P,Czubkowski P,Rock N,Shagrani M,Broering D,Algoufi T,Mazhar N,Nicastro E,Kelly DA,Nebbia G,A

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND & AIMS:Non-alcoholic steatohepatitis (NASH) is a leading cause of chronic liver disease in Western countries. It is unclear how infiltrating leukocytes affect NASH-development. Our study aims to investigate the role of the homing/receptor, pair mucosal addressin cell adhesion molecule-1 (MAdCAM-1)/β7-Integri...

journal_title：Journal of hepatology

authors： Drescher HK,Schippers A,Clahsen T,Sahin H,Noels H,Hornef M,Wagner N,Trautwein C,Streetz KL,Kroy DC

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND/AIMS:Gadolinium chloride inactivates Kupffer cells and alleviates alcohol-induced liver lesions. We investigated the mechanism of gadolinium chloride protection after oral ethanol feeding. METHODS:Rats were maintained ethanol-intoxicated for 6 weeks by feeding ethanol in a low-carbohydrate/high-fat liquid d...

journal_title：Journal of hepatology

authors： Järveläinen HA,Fang C,Ingelman-Sundberg M,Lukkari TA,Sippel H,Lindros KO

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND/AIMS:Patients infected with hepatitis C virus (HCV) genotype 2 or 3 usually respond better to interferon (IFN) treatment than those infected with genotype 1. In this study, we investigated whether the non-structural 5A protein (NS5A) of HCV genotypes 1 and 2 (1b-NS5A and 2a-NS5A, respectively) exerted differ...

journal_title：Journal of hepatology

authors： Tsai YH,Kuang WF,Lu TY,Kao JH,Lai MY,Liu CJ,Chen PJ,Hwang LH

更新日期：2008-12-01 00:00:00

abstract：:Because of global epidemics of obesity and type 2 diabetes, the prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing both in Europe and the United States, becoming one of the most frequent causes of chronic liver disease and predictably, one of the leading causes of liver transplantation both for end-...

journal_title：Journal of hepatology

authors： Pais R,Barritt AS 4th,Calmus Y,Scatton O,Runge T,Lebray P,Poynard T,Ratziu V,Conti F

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND/AIMS:Terlipressin is a long-acting vasopressin analogue that has been proved useful in the treatment of variceal haemorrhage. This study investigates the time profile of the haemodynamic effects of terlipressin on portal hypertension as well as the efficacy in decreasing portal-pressure and collateral blood ...

journal_title：Journal of hepatology

authors： Escorsell A,Bandi JC,Moitinho E,Feu F,García-Pagan JC,Bosch J,Rodés J

更新日期：1997-03-01 00:00:00

abstract：:The results of a 3-year, placebo-controlled trial of prednisolone treatment in primary biliary cirrhosis (PBC) are presented. The active (n = 19) and placebo (n = 17) arms were initially well matched for age, menopausal status and disease severity. At 3 years hepatic symptoms were relatively improved in the prednisolo...

journal_title：Journal of hepatology

authors： Mitchison HC,Palmer JM,Bassendine MF,Watson AJ,Record CO,James OF

更新日期：1992-07-01 00:00:00

abstract：:Portal vein thrombosis is not uncommon in candidates for transplantation. Partial thrombosis is more common than complete thrombosis. Despite careful screening at evaluation, a number of patients are still found with previously unrecognized thrombosis per-operatively. The objective is to recanalize the portal vein or,...

journal_title：Journal of hepatology

authors： Francoz C,Valla D,Durand F

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND & AIMS:In developed countries, hepatitis E is usually associated with travelling to endemic areas, but a growing number of sporadic cases are also seen in patients with no travel history. The aim of this study was to assess the impact and the molecular epidemiology of hepatitis E in Italy. METHODS:Between J...

journal_title：Journal of hepatology

authors： Romanò L,Paladini S,Tagliacarne C,Canuti M,Bianchi S,Zanetti AR

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND & AIMS:Biliary atresia (BA) is a pediatric inflammatory disease of the biliary system which leads to cirrhosis and the need for liver transplantation. One theory regarding etiology is that bile duct injury is due to virus-induced autoreactive T cell-mediated inflammation. Regulatory T cell (Treg) abnormaliti...

journal_title：Journal of hepatology

authors： Tucker RM,Feldman AG,Fenner EK,Mack CL

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND & AIMS:Genetic variants of patatin-like phospholipase domain-containing 3 (PNPLA3) and diabetes are associated with liver disease severity, in patients with chronic hepatitis C (CHC) infection. We aimed at exploring their interaction in determining hepatitis C virus (HCV)-related liver fibrosis. METHODS:The...

journal_title：Journal of hepatology

authors： Huang CF,Dai CY,Yeh ML,Huang CI,Tai CM,Hsieh MH,Liang PC,Lin YH,Hsieh MY,Yang HL,Huang JF,Lin ZY,Chen SC,Yu ML,Chuang WL

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND/AIMS:Combinations of beta-blockers and vasodilators have been assessed for their ability to lower portal pressure and so prevent variceal haemorrhage. However, reservations have been raised particularly with respect to renal function and perfusion after the use of these medicines in patients with chronic liv...

journal_title：Journal of hepatology

authors： Forrest EH,Bouchier IA,Hayes PC

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND & AIMS:Living donor liver transplantation (LDLT) provides a timely alternative to deceased donor liver transplantation (DDLT) for patients with hepatitis C virus-related (HCV-related) diseases in the circumstances of severe organ dearth. However, the patient and graft outcomes, and recurrence of HCV after LD...

journal_title：Journal of hepatology

authors： Hu A,Liang W,Zheng Z,Guo Z,He X

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND/AIMS:Lipid peroxidation has been found to be associated with Ito cell activation. Ito cells are the principal collagen-producing cells and the main storage sites of retinoids. However, the relationship between retinoids and hepatic fibrosis is complex. The aim of this study was to elucidate the role of retin...

journal_title：Journal of hepatology

authors： Mizobuchi Y,Shimizu I,Yasuda M,Hori H,Shono M,Ito S

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND/AIMS:Bio-artificial liver support systems for treatment of hepatic failure require maintained expression of hepatocyte function in vitro. We studied cultures of human hepatocyte cell-lines proliferating within alginate beads, investigating the hypothesis that 3-dimensional cohesive colonies of hepatocyte cel...

journal_title：Journal of hepatology

authors： Khalil M,Shariat-Panahi A,Tootle R,Ryder T,McCloskey P,Roberts E,Hodgson H,Selden C

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND/AIMS:The liver is the main source of circulating insulin-like growth factor binding proteins. In man, the cellular origin of insulin-like growth factor binding proteins has remained obscure. METHODS:Human hepatocytes isolated from surgical specimens were purified and cultured using a collagen gel immobiliza...

journal_title：Journal of hepatology

authors： Scharf JG,Schmidt-Sandte W,Pahernik SA,Koebe HG,Hartmann H

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND & AIMS:Hepatocellular carcinoma (HCC) is a common cancer worldwide and remains a major clinical challenge. Ketoconazole, a traditional antifungal agent, has attracted considerable attention as a therapeutic option for cancer treatment. However, its mechanism of action is still not clearly defined. We aimed t...

journal_title：Journal of hepatology

authors： Chen Y,Chen HN,Wang K,Zhang L,Huang Z,Liu J,Zhang Z,Luo M,Lei Y,Peng Y,Zhou ZG,Wei Y,Huang C

更新日期：2019-01-01 00:00:00

abstract：:Chronic hepatitis C is common in Saudi Arabia and most often presents in an advanced stage. To assess the response of patients to interferon, a randomized placebo-controlled double-blind study was undertaken. All but 1 patient had cirrhosis or fibrosis before interferon. After a 24-week observation period patients rec...

journal_title：Journal of hepatology

authors： Sieck JO,Ellis ME,Alfurayh O,Ali MA,Ali HA,Ayub A,al-Fadda M,Zafar M,Halim M,Bernvil SS

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND/AIMS:Partial hepatectomy results in activation of genes in the residual liver tissue which serve to restore glucose homeostasis and regenerate liver mass. Expression of insulin-like growth factor binding protein-1 (IGFBP-1) is up-regulated following partial hepatectomy and IGFBP-1 can modulate both the metab...

journal_title：Journal of hepatology

authors： Liu YY,Rajkumar K,Murphy LJ

更新日期：1999-04-01 00:00:00