Abstract：
:The membrane phospholipids of the brain contain high levels of polyunsaturated fatty acids (PUFA), particularly arachidonic acid, 20:4n-6 and docosahexaenoic acid, 22:6n-3. These long-chain PUFA are synthesized from their respective essential fatty acid (EFA) precursors, linoleic acid, 18:2n-6 and linolenic acid, 18:3n-3. Although the necessity of n-6 fatty acids for optimum growth has been established, a similar requirement for those of the n-3 family is less clear. The rapid accumulation of the long-chain n-3 PUFA in the brain during prenatal and preweaning development suggests that the provision of n-3 fatty acids to the developing brain may be necessary for normal growth and functional development. The intent of this review is to assess the experimental work which addresses this question, most of which has been conducted on rodents. The emphasis will be on studies which measure behavioral outcomes, and particular attention will be paid to methodological issues which affect the interpretation of these data. An integration of the research findings will be presented and discussed in light of possible implications for therapeutic interventions.
journal_name
Neurosci Biobehav Revjournal_title
Neuroscience and biobehavioral reviewsauthors
Wainwright PEdoi
10.1016/s0149-7634(05)80180-0subject
Has Abstractpub_date
1992-07-01 00:00:00pages
193-205issue
2eissn
0149-7634issn
1873-7528pii
S0149-7634(05)80180-0journal_volume
16pub_type
杂志文章,评审abstract：:Because the presence or absence of memories in the brain cannot be directly observed, scientists must rely on indirect measures and use inferential reasoning to make statements about the status of memories. In humans, memories are often accessed through spoken or written language. In animals, memory is accessed throug...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2004.09.013
更新日期：2004-11-01 00:00:00
abstract：:Here we review the role of brain oscillations in sensory processing. We examine the idea that neural entrainment of intrinsic oscillations underlies the processing of rhythmic stimuli in the context of simple isochronous rhythms as well as in music and speech. This has been a topic of growing interest over recent year...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2017.12.002
更新日期：2018-03-01 00:00:00
abstract：:The cortico-reticular theory of absence epilepsy explains the origin of the bilateral generalized spike-wave discharges (SWDs) characterizing absence seizures via a subcortical pacemaker that is responsible for both normal sleep spindles and pathological SWDs. This pacemaker is the reticular thalamic nucleus (RTN); it...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2006.03.002
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:Asymptomatic carotid stenosis (CS), traditionally considered clinically silent, may be an independent risk factor for a cognitive impairment. METHODS:To determine whether an association exists between asymptomatic CS and cognitive function, we systematically reviewed the literature in the Cochrane Library, ...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2013.05.011
更新日期：2013-09-01 00:00:00
abstract：:Life expectancy in the last century has greatly increased although, in most industrialized countries, this has been paralleled by an increased incidence of neurodegenerative disorders, in addition to cardiovascular and metabolic pathologies. The p66(Shc) gene has emerged as a novel gerontogene affecting health through...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2013.03.005
更新日期：2013-06-01 00:00:00
abstract：:Most models of conduct disorders are based on a biopsychosocial perspective. In such models, genetic and/or neuropsychological determinants are assumed to have a core hierarchical role by conferring vulnerabilities during a child's development. Based on a review of recent literature, I will show that other views are a...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2009.07.011
更新日期：2010-01-01 00:00:00
abstract：:Guidelines for assessing fitness to drive in individuals with neurodegenerative disorders, such as Parkinson's disease (PD), are subjective. It is therefore timely to review the current status of the literature not only for health professionals who are required to assess fitness to drive, but also for the development ...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2008.08.005
更新日期：2009-03-01 00:00:00
abstract：:The objective of the current review is to integrate information from a series of studies, employing a paradigm that evaluates local contextual processing using electrophysiological measures. Collectively these studies provide an overview of how utilization of predictive context changes as a function of stimulus modali...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2015.02.016
更新日期：2015-05-01 00:00:00
abstract：:In ingestive taste reactivity analysis, the rhythmic oral motor responses observed during intraoral infusion of fluids normally ingested by rats are categorized and counted. These rhythmic movements can be likened to spout-licking in several respects. Both are emitted in the same frequency range (5-8 Hz), organized in...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/0149-7634(94)00023-t
更新日期：1995-04-01 00:00:00
abstract：:Two hundred and ten patients with Tourette Syndrome (TS) and/or their parents completed a survey, answering questions about the frequency and disruptiveness of vocal and motor tics, behaviour problems and sleep disturbances. Respondents also rated the impact of TS symptoms on social relationships and level of personal...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/s0149-7634(88)80054-x
更新日期：1988-10-01 00:00:00
abstract：:Cocaine remains one of the most addictive substances of abuse and one of the most difficult to treat. Although increasingly sophisticated experimental and technologic advancements in the last several decades have yielded a large body of clinical and preclinical knowledge on the direct effects of cocaine on the brain, ...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2013.04.007
更新日期：2013-11-01 00:00:00
abstract：:Gray's approach to understanding hippocampal functioning [The Neuropsychology of Anxiety: An Enquiry into the Function of the Septo-hippocampal System, 1982; The Neuropsychology of Anxiety, 2000] departs from the prevailing view of that structure as a substrate for memory. Instead, Gray and McNaughton have proposed th...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2004.02.001
更新日期：2004-05-01 00:00:00
abstract：:Heavy prenatal alcohol exposure causes permanent structural alterations to the brain and can lead to numerous cognitive and behavioral outcomes. Consistent with many of the neuropsychological and behavioral deficits that have been reported, neuroimaging studies reveal a pattern of structural abnormalities associated w...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2006.09.006
更新日期：2007-01-01 00:00:00
abstract：:Tourette syndrome (TS) is a neuropsychiatric disorder involving motor and phonic tics. Inhibitory control is a key issue in TS, and many disruptive or impulsive behaviors might arise from inhibitory deficits. However, conflicting findings regarding TS patients' inhibitory performance in neuropsychological tasks have b...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.neubiorev.2017.05.006
更新日期：2017-09-01 00:00:00
abstract：:Evidence suggests that omega-3 fatty acids are important for a variety of mental health outcomes and have been shown to improve both mood and behaviors. However, there is little consensus on whether omega-3 fatty acids are beneficial for reducing aggressive behaviors. The current study assesses the relationship betwee...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.neubiorev.2016.07.017
更新日期：2016-10-01 00:00:00
abstract：:The present article discusses the distribution of free radical processes in the central nervous system (CNS). Specifically, we discuss the involvement of oxyradicals in the normal metabolism of catecholamine. We also review some proposals related to the possible importance of these compounds in the development of neur...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/0149-7634(94)90001-9
更新日期：1994-01-01 00:00:00
abstract：:We investigated whether genetic differences in various forms of intraspecific aggression and anxiety in four different genetic lines of mice (i.e. wild, outbred Swiss-CD1, inbred DBA/2 and inbred C57/BL6N) may reflect modifications in behavioral strategy. Experiments 1 and 2 used ethologically based paradigms to analy...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(99)00029-9
更新日期：1999-11-01 00:00:00
abstract：:The term 'learned helplessness' refers to a constellation of behavioral changes that follow exposure to stressors that are not controllable by means of behavioral responses, but that fail to occur if the stressor is controllable. This paper discusses the nature of learned helplessness, as well as the role of the dorsa...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2005.03.021
更新日期：2005-01-01 00:00:00
abstract：:The prefrontal cortex (PFC) mediates a range of higher order 'executive functions' that subserve the selection and processing of information in such a way that behavior can be planned, controlled and directed according to shifting environmental demands. Impairment of executive functions typifies many forms of psychopa...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2008.11.005
更新日期：2009-06-01 00:00:00
abstract：:In this paper, we show that differences in dominance and spatial centrality of individuals in a group may arise through self-organisation. Our instrument is a model, called DomWorld, that represents two traits that are often found in animals, namely grouping and competing. In this model individual differences grow und...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/j.neubiorev.2004.07.003
更新日期：2005-02-01 00:00:00
abstract：:Human adolescence is a time of enormous developmental change, second only to infancy and early childhood in terms of brain shaping and growth. It is also a period in life when the young adult is faced with distinct environmental challenges and stressors. Interestingly, we now know that these external sources of stress...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2016.06.005
更新日期：2016-11-01 00:00:00
abstract：:Risk assessment is the attempt to characterize the chance of obtaining an adverse effect after exposure to an agent. Traditionally, high levels of an agent have been used to estimate the likelihood a lower dose might have an effect either by using low-dose extrapolation models or by attempting to establish a dose with...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/s0149-7634(05)80108-3
更新日期：1991-04-01 00:00:00
abstract：:Abnormalities in the simplest form of learning, habituation, have been reported in a variety of neuropsychiatric disorders as etiologically diverse as Autism Spectrum Disorder, Fragile X syndrome, Schizophrenia, Parkinson's Disease, Huntington's Disease, Attention Deficit Hyperactivity Disorder, Tourette's Syndrome, a...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2017.05.028
更新日期：2017-09-01 00:00:00
abstract：:Birdsong shows striking parallels with human speech. Previous comparisons between birdsong and human vocalizations focused on syntax, phonology and phonetics. In this review, we propose that future comparative research should expand its focus to include prosody, i.e. the temporal and melodic properties that extend ove...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2017.02.016
更新日期：2017-10-01 00:00:00
abstract：:Post-stroke depression (PSD) is the most common mental health issue, afflicting around 33% of stroke survivors. PSD has a negative impact on the rehabilitation, recuperation of motor and cognitive deficits following stroke and significantly increases the chances of relapsing neurovascular events. It has been demonstra...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2018.04.005
更新日期：2018-07-01 00:00:00
abstract：:Although neuroimaging investigations in human cocaine abusers have provided important insights into the brain changes that accompany drug use, the interpretation of reports in human abusers can be very difficult. Studies in nonhuman primates provide a way to systematically evaluate the structural and functional adapta...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2003.11.013
更新日期：2004-01-01 00:00:00
abstract：:The adaptive control of behaviour in response to relevant external objects and events often requires the selection of information delivered by different sensory systems, but from the same region in external space. This can be facilitated by crossmodal links in the attentional processing of information across sensory m...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/s0149-7634(01)00029-x
更新日期：2001-08-01 00:00:00
abstract：:The cognitive states that underlie animal behavior may include conscious, subjective, mental experiences. Familiar arguments to the contrary are inconclusive. Interactive communication between social animals may well include the exchange of information about subjective feelings and thoughts. Objective data about the s...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章
doi：10.1016/0149-7634(85)90008-9
更新日期：1985-01-01 00:00:00
abstract：:Less than two decades after its inception, the burgeoning field of neuroaesthetics continues to grow in interest and momentum. Despite the biological and social importance of the human body and the attention people pay to its appearance in daily life, only recently has neuroaesthetic inquiry turned its attention to qu...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2015.12.005
更新日期：2016-03-01 00:00:00
abstract：:One view of language origins sees it as ancient and selection-driven; the other as recent and emergent. Such disagreement occurs because language is ephemeral, detectable only by indirect proxies. Because internalized language and symbolic thought are tightly linked, the best archaeological proxies for language are sy...
journal_title：Neuroscience and biobehavioral reviews
pub_type： 杂志文章,评审
doi：10.1016/j.neubiorev.2017.01.043
更新日期：2017-10-01 00:00:00
