Abstract:
:The present article discusses the distribution of free radical processes in the central nervous system (CNS). Specifically, we discuss the involvement of oxyradicals in the normal metabolism of catecholamine. We also review some proposals related to the possible importance of these compounds in the development of neuropsychiatric and movement disorders such as schizophrenia and neuroleptic-induced tardive dyskinesia (TD), respectively. Clinical studies have shown that antioxidant treatment can attenuate the movement abnormalities observed in TD. Further studies are necessary to evaluate the status of specific scavenging systems in these two disorders. The prophylactic use of antioxidants in patients who are treated with neuroleptics needs also to be considered.
journal_name
Neurosci Biobehav Revjournal_title
Neuroscience and biobehavioral reviewsauthors
Cadet JL,Kahler LAdoi
10.1016/0149-7634(94)90001-9subject
Has Abstractpub_date
1994-01-01 00:00:00pages
457-67issue
4eissn
0149-7634issn
1873-7528journal_volume
18pub_type
杂志文章,评审abstract::Many psychiatric illnesses are associated with early mortality and with an increased risk of developing physical diseases that are more typically seen in the elderly. Moreover, certain psychiatric illnesses may be associated with accelerated cellular aging, evidenced by shortened leukocyte telomere length (LTL), which...
journal_title:Neuroscience and biobehavioral reviews
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abstract::For human and non-human primates, vision is one of the most privileged sensory channels used to interact with the environment. The importance of vision is strongly embedded in the organization of the primate brain as about one third of its cortical surface is involved in visual functions. It is therefore not surprisin...
journal_title:Neuroscience and biobehavioral reviews
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doi:10.1016/j.neubiorev.2013.08.001
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abstract::The study of 5-hydroxytryptamine (5-HT) system has benefited from the identification, classification and cloning of multiple 5-HT receptors (5-HT1 to 5-HT7). Growing evidence suggests that 5-HT is important in learning and memory and all its receptors might be implicated in this. Actually, 5-HT pathways, 5-HT reuptake...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
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更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:Although antidepressants are effective, around 50% of depressed patients are non-responsive. At the same time, some patients show alterations in the hypothalamic-pituitary-adrenal (HPA) axis. Due to interactions with central monoaminergic systems, these may profit less from antidepressants. METHOD:To determi...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,meta分析,评审
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abstract::Pupillometry, measuring pupil size and reactivity, has been proposed as a measure of autonomic nervous system functioning, the latter which might be altered in individuals with autism spectrum disorder (ASD). This study aims to evaluate if pupillary responses differ in individuals with and without ASD. After performin...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2020.09.032
更新日期:2020-10-22 00:00:00
abstract::Sex is often overlooked in animal and human research. Cognitive impairment associated with schizophrenia (CIAS) remains an unmet clinical need, as current antipsychotic medication does not provide clinically meaningful improvements. One explanation could be lack of appreciation of gender differences in CIAS. Animal mo...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
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journal_title:Neuroscience and biobehavioral reviews
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更新日期:1990-07-01 00:00:00
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journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章
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journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
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journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2006.06.009
更新日期:2006-01-01 00:00:00
abstract::Exposure to maternal infection in utero increases the risk that offspring will develop neurodevelopmental disorders such as autism spectrum disorder (ASD) and schizophrenia. Research in animal models has confirmed this link and demonstrated that maternal immune activation (MIA) is sufficient to induce alterations in o...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章
doi:10.1016/j.neubiorev.2019.06.020
更新日期:2019-09-01 00:00:00
abstract::Liver glycogen content was determined in free feeding rats sacrificed at the beginning of nocturnal meals or 60 min later. It was found that the glycogen content at the beginning of meals and 60 min later was highly correlated with the cumulative food intake since the beginning of the dark cycle, and therefore, increa...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章
doi:10.1016/0149-7634(80)90044-5
更新日期:1980-01-01 00:00:00
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journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/s0149-7634(88)80008-3
更新日期:1988-07-01 00:00:00
abstract::Unilateral Spatial Neglect (USN) can be considered as a defect in spatial orienting of attention toward the half space contralateral to the damaged hemisphere. Since the classical work of Brain, W.R. Brain 64:224-272 (1941), several authors have emphasized that this defect is definitely more frequent and severe in pat...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/0149-7634(95)00074-7
更新日期:1996-01-01 00:00:00
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journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2017.04.021
更新日期:2017-07-01 00:00:00
abstract::Smokers have substantial individual differences in quit success in response to current treatments for nicotine dependence. This observation may suggest that different underlying motivations for continued tobacco use across individuals and nicotine cessation may require different treatments in different individuals. Al...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2015.06.004
更新日期:2015-11-01 00:00:00
abstract::Drug addiction affects approximately 10% of the population and these numbers are rising. Treatment and prevention of addiction are impeded by current diagnostic systems, such as DSM-5, which are based on outcomes rather than processes. Here, we review the importance of adopting a dimensional framework, specifically th...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2018.06.005
更新日期:2019-11-01 00:00:00
abstract::An atypical pattern of eye contact behaviour is one of the most significant symptoms of Autism Spectrum Disorder (ASD). Recent empirical advances have revealed the developmental, cognitive and neural basis of atypical eye contact behaviour in ASD. We review different models and advance a new 'fast-track modulator mode...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
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journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/0149-7634(84)90005-8
更新日期:1984-01-01 00:00:00
abstract::We have shown repeatedly that pre-treatment of neonatal rats with dexamethasone provides protection against hypoxic-ischemic brain damage. Although the mechanism of action is not certain, hypothermia, an alteration in cerebral perfusion or an induction of antioxidant enzymes does not readily explain this effect. A rel...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
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更新日期:1997-03-01 00:00:00
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journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章
doi:10.1016/j.neubiorev.2019.05.001
更新日期:2019-07-01 00:00:00
abstract::Rapid instructed task learning (RITL) is one of the most remarkable human abilities, when considered from both computational and evolutionary perspectives. A key feature of RITL is that it enables new goals to be immediately pursued (and shared) following formation of task representations. Although RITL is a form of c...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2017.02.009
更新日期:2017-10-01 00:00:00
abstract::It has been widely accepted that the younger the age and/or immaturity of the organism, the greater the brain plasticity, the young age plasticity privilege. This paper examines the relation of a young age to plasticity, reviewing human pediatric brain disorders, as well as selected animal models, human developmental ...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2013.09.010
更新日期:2013-12-01 00:00:00
abstract::This review focuses on facial recognition abilities in children and adolescents with attention deficit hyperactivity disorder (ADHD). A systematic review, using PRISMA guidelines, was conducted to identify original articles published prior to May 2017 pertaining to memory, face recognition, affect recognition, facial ...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章
doi:10.1016/j.neubiorev.2018.03.026
更新日期:2018-06-01 00:00:00
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journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/0149-7634(84)90007-1
更新日期:1984-01-01 00:00:00
abstract::Drug addiction is a chronic and relapsing disorder in which repeated drug exposure compromises brain neuroplasticity. Brain areas normally involved in learning and goal-directed behaviors become corrupted, which may lead to cognitive deficits that coexist with other addiction symptoms and predict a worse treatment out...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2018.11.015
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journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2017.04.007
更新日期:2017-07-01 00:00:00
abstract::Experiments involving the use of LSD and observing its effects on neurons involved in the processing of visual information are reviewed. These studies typically involved either intravenous or iontophoretic application of the compound. Both modes of application appeared to block the optic afferent synapse at the level ...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章
doi:10.1016/0149-7634(82)90032-x
更新日期:1982-01-01 00:00:00
abstract::The risk of improbable, uncertain, but grave potential dangers poses unique adaptive challenges. We argue that to manage such risks, a special motivational system evolved, which we term the security motivation system. Review of work across a range of species indicates that this system is designed to detect subtle indi...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/j.neubiorev.2010.08.003
更新日期:2011-03-01 00:00:00
abstract::Lick sensors are versatile instruments that are routinely used in behavioral and neuroscience research involving fluid ingestion in the rat. There are three different types of sensors: electrical, optical and force sensors. They differ in the exact moment of activation during the tongue protrusion/retraction cycle. Pr...
journal_title:Neuroscience and biobehavioral reviews
pub_type: 杂志文章,评审
doi:10.1016/s0149-7634(98)00003-7
更新日期:1998-10-01 00:00:00