Abstract:
:Drug addiction is a chronic and relapsing disorder in which repeated drug exposure compromises brain neuroplasticity. Brain areas normally involved in learning and goal-directed behaviors become corrupted, which may lead to cognitive deficits that coexist with other addiction symptoms and predict a worse treatment outcome. New learning experiences that are not motivated by drugs may improve both cognitive deficits and drug-induced symptoms by promoting adaptive neuroplastic changes that could alleviate or reverse those involved in addiction. The present review will focus on whether potentiating healthy cognitive function, either by formal cognitive training or non-drug related environmental experiences, could exert beneficial effects in the therapeutics of addiction. Although additional studies are needed, the available clinical and preclinical evidence suggests that cognitive stimulation may provide a valuable adjuvant intervention in drug addiction.
journal_name
Neurosci Biobehav Revjournal_title
Neuroscience and biobehavioral reviewsauthors
Sampedro-Piquero P,Ladrón de Guevara-Miranda D,Pavón FJ,Serrano A,Suárez J,Rodríguez de Fonseca F,Santín LJ,Castilla-Ortega Edoi
10.1016/j.neubiorev.2018.11.015subject
Has Abstractpub_date
2019-11-01 00:00:00pages
23-48eissn
0149-7634issn
1873-7528pii
S0149-7634(18)30294-Xjournal_volume
106pub_type
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