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The contributions of resting state and task-based functional connectivity studies to our understanding of adolescent brain network maturation.

Abstract：

:This review summarizes functional magnetic resonance imaging (fMRI) research done over the past decade that examined changes in the function and organization of brain networks across human adolescence. Its over-arching goal is to highlight how both resting state functional connectivity (rs-fcMRI) and task-based functional connectivity (t-fcMRI) have jointly contributed - albeit in different ways - to our understanding of the scope and types of network organization changes that occur from puberty until young adulthood. These two approaches generally have tested different types of hypotheses using different analysis techniques. This has hampered the convergence of findings. Although much has been learned about system-wide changes to adolescents' neural network organization, if both rs-fcMRI and t-fcMRI approaches draw upon each other's methodology and ask broader questions, it will produce a more detailed connectome-informed theory of adolescent neurodevelopment to guide physiological, clinical, and other lines of research.

journal_name

Neurosci Biobehav Rev

journal_title

Neuroscience and biobehavioral reviews

authors

Stevens MC

doi

10.1016/j.neubiorev.2016.07.027

subject

Has Abstract

pub_date

2016-11-01 00:00:00

pages

13-32

eissn

0149-7634

issn

1873-7528

pii

S0149-7634(16)30082-3

journal_volume

70

pub_type

杂志文章,评审

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